Vous êtes ici :   Accueil » Sommaires des Revues - Mayo Clinic Proceedings
 
Prévisualiser...  Imprimer...  Imprimer la page...
Menu Principal
Recherche
Recherche
Journal de Neurochirurgie

couv01.jpg

Publications
Sommaires des Revues - Mayo Clinic Proceedings

Mayo Clinic Proceedings

http://www.mayoclinicproceedings.org/issues?publicationCode=jmcp&rss=yes


Mayo Clinic Proceedings RSS feed.


“Needs More Research”—Implications of the Proteus Effect for Researchers and Evidence Adopters  Voir?

As a researcher, I try to avoid starting the concluding paragraph of the manuscript reporting my study's findings with, “We need more research to better understand….” Every researcher wants to perform the definitive study that provides the definitive answer, and funding agencies prefer not to support researchers to repeat studies again and again. Yet Alahdab and colleagues1 show us in this issue of Mayo Clinic Proceedings that treatment trials published early in the chain of evidence can present exaggerated effects.

... / ... Lire la suite

(???)

Treatment Effect in Earlier Trials of Patients With Chronic Medical Conditions: A Meta-Epidemiologic Study  Voir?

To determine whether the early trials in chronic medical conditions demonstrate an effect size that is larger than that in subsequent trials.
(???)

Factors Associated With Positive Margins in Women Undergoing Breast Conservation Surgery  Voir?

To identify factors predicting positive margins at lumpectomy prompting intraoperative reexcision in patients with breast cancer treated at a large referral center.
(???)

Routine Invasive Versus Selective Invasive Strategy in Elderly Patients Older Than 75 Years With Non-ST-Segment Elevation Acute Coronary Syndrome: A Systematic Review and Meta-Analysis  Voir?

To evaluate outcomes of routine invasive strategy (RIS) compared with selective invasive strategy (SIS) in elderly patients older than 75 years with non-ST-segment elevation acute coronary syndrome (NSTE-ACS).
(???)

Association of Resistance Exercise With the Incidence of Hypercholesterolemia in Men  Voir?

To examine the associations of resistance exercise, independent of and combined with aerobic exercise, with the risk of development of hypercholesterolemia in men.
(???)

Frequency of Acute and Subacute Infarcts in a Population-Based Study  Voir?

To determine the frequency of incidental acute or subacute cerebral infarction (CI) in a population-based study.
(???)

The Changing Incidence and Presentation of Urinary Stones Over 3 Decades  Voir?

To evaluate trends in the incidence of kidney stones and characteristics associated with changes in the incidence rate over 3 decades.
(???)

In Reply–Cardiac Compromise in Zika Virus Infection  Voir?

We read with interest the letter from Villamil-Goméz et al,1 which reinforces the possibility of frequent subclinical cardiovascular involvement in Zika virus (ZIKV) infection, especially in immunocompromised patients.
(???)

28-Year-Old Man With Fever, Malaise, and Diarrhea  Voir?

A 28-year-old man presented to the outpatient clinic with pharyngitis. Rapid streptococcal antigen testing was negative, and he was treated supportively. Four weeks later, he developed dysuria. Sexually transmitted infection testing revealed chlamydia and he was treated with azithromycin and ceftriaxone.

... / ... Lire la suite

(???)

42-Year-Old Woman With Bilateral Arm Tightness  Voir?

A 42-year-old woman presented to the emergency department (ED) with acute-onset crushing substernal chest pain that occurred while working in the hospital as a sign language interpreter. At 8:15 am, she developed bilateral arm tightness and heaviness that subsequently radiated to her chest. The symptoms were associated with shortness of breath and nausea. She was urgently transported to the ED.

... / ... Lire la suite

(???)

65-Year-Old Woman With Chronic Eosinophilia  Voir?

A 65-year-old Cambodian woman presented to clinic for a general medical examination. Aside from chronic constipation associated with mild abdominal pain, she felt well. Review of her records revealed a 2-decade history of normocytic anemia and mild eosinophilia, both of unknown etiology, and 7 years of worsening kidney function, with her most recent creatinine suggesting chronic kidney disease stage 3. She had no other significant medical history. Labs were notable for normal electrolytes. Her medications included calcium, vitamin D, and vitamin B12 supplements for previous diagnoses of osteopenia and vitamin B12 deficiency.

... / ... Lire la suite

(???)

52-Year-Old Man With Hyposmia, Rhinorrhea, and Wheezing  Voir?

A 52-year-old man presents for evaluation of persistent nasal congestion, hyposmia, rhinorrhea, and wheezing. He had a medical history of gout and gastroesophageal reflux disease. His symptoms initially developed 7 years earlier when he experienced anosmia associated with rhinorrhea and a constant sense of fullness behind the eyebrows. He was diagnosed with nasal polyposis and chronic sinusitis following a computed tomography (CT) of the paranasal sinuses. Over the course of 3 years he underwent multiple surgical procedures including nasal polypectomy and functional endoscopic sinus surgery with clinical improvement.

... / ... Lire la suite

(???)

70-Year-Old Woman With Sudden Onset of Chest Pain and Diaphoresis  Voir?

A 70-year-old woman presented to the emergency department with sudden-onset chest pain of 3 hours duration. She described it as pressing, heavy, substernal with radiation to left shoulder, and associated with profound dyspnea, palpitations, and diaphoresis. Just before symptom onset, her dog had chased her cat, knocking over a birdcage, and causing her bird to escape. The discomfort began immediately after she attempted to corral her dog. She denied any change in her symptoms with exertion or rest.

... / ... Lire la suite

(???)

Cardiac Compromise in Zika Virus Infection  Voir?

We have read with interest the case report of Schwartzmann et al1 reporting a single case of Zika virus (ZIKV) meningoencephalitis, but also with ZIKV propagation to other organs, including the heart. As in other arboviral diseases (dengue and chikungunya),2-4 cardiovascular disorders such as arrhythmias, among others, are being observed in previously healthy cases. But there is a lack of publications assessing it. We take this opportunity to discuss 2 cases of pregnant women from an endemic area (Sucre, Colombia), with confirmed ZIKV infection who presented with cardiovascular and electrocardiographical (ECG) alterations (myocarditis).

... / ... Lire la suite

(???)

The Current Role of Bevacizumab in the Treatment of Hereditary Hemorrhagic Telangiectasia–Related Bleeding  Voir?

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder with a worldwide prevalence rate of approximately 1 case per 5000 persons that results in vascular malformations throughout the body. At least 90% of patients are affected by nosebleeds and up to 81% have gastrointestinal telangiectasias.1 Both of these can result in severe bleeding and anemia that are refractory to conventional therapy (eg, iron infusions and endoscopic cautery of gastrointestinal and nasal telangiectasias) in perhaps as many as 10% to 15% of patients.

... / ... Lire la suite

(???)

Disease Progression and End-Stage Renal Disease in Diverse Glomerulopathies  Voir?

Chronic kidney disease (CKD) is not a functionally static process but rather a potentially progressive one that may culminate in end-stage renal disease (ESRD). The onset of ESRD is a turning point in the course of CKD because ESRD substantially alters the patient's lifestyle and imposes increased morbidity and mortality in patients so afflicted. For most patients, ESRD is managed by in-center hemodialysis, a treatment modality that obligates, among other requirements, the placement and functionality of a vascular access for hemodialysis; the need to travel thrice weekly to the dialysis center; thrice-weekly hemodialysis treatments lasting 3 or more hours; tolerance to the recurrent lassitude and generalized lack of well-being often experienced after each hemodialysis treatment; and restricted intake of fluids and assorted dietary constituents.

... / ... Lire la suite

(???)

Intravenous Bevacizumab for Refractory Hereditary Hemorrhagic Telangiectasia–Related Epistaxis and Gastrointestinal Bleeding  Voir?

To present a multiyear clinical experience with intravenous bevacizumab for the management of severe gastrointestinal bleeding and/or epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT).
(???)

End-Stage Renal Disease and Mortality Outcomes Across Different Glomerulonephropathies in a Large Diverse US Population  Voir?

To compare renal function decline, incident end-stage renal disease (ESRD), and mortality among patients with 5 common glomerular diseases in a large diverse population.
(???)

Reducing Risk of Dementia in AF—Is Oral Anticoagulation the Key?  Voir?

The prevalence of dementia and atrial fibrillation (AF) are both on the rise with the aging population and increasing burden of vascular risk factors. Numerous studies have described an association between AF and dementia.1-4 However, little is known about strategies that could be employed to reduce the risk of dementia in those with AF. In this context, Madhavan et al5 have attempted to address this gap by examining the effect of warfarin on the risk of incident dementia in a community cohort of patients with AF.

... / ... Lire la suite

(???)

The Evolving Face of Myocardial Reperfusion in Acute Coronary Syndromes: A Primer for the Internist  Voir?

Acute coronary syndromes (ACSs) account for a large proportion of disease burden in the United States and worldwide, and our understanding of ACS management continues to evolve. In this review we take a practical approach to evaluating and treating a patient with ACS, focusing on the optimal timing and methods of coronary reperfusion. Beginning with initial assessment and risk stratification, a provider managing the patient with ACS must be able to expeditiously decide on and implement the correct guideline-directed pathway to optimize outcomes.

... / ... Lire la suite

(???)

Efficacy of Warfarin Anticoagulation and Incident Dementia in a Community-Based Cohort of Atrial Fibrillation  Voir?

To study the association between time in therapeutic range (TTR) during warfarin therapy and risk of dementia in a population-based cohort of incident atrial fibrillation (AF).
(???)

Aortic Root Dilation in Patients With Leptosomic Features  Voir?

Marfan syndrome is an autosomal-dominant disorder usually due to mutations in the FBN1 gene, which encodes the protein fibrillin; a mutation in FBN1 can be defined in up to 97% of the patients with Marfan syndrome.1 Patients with Marfan syndrome are at risk for developing aortic aneurysm and dissection, and these patients need genetic and exercise counseling, and regular follow-up to monitor aortic size to determine the timing for aortic root replacement. These risks of aortic aneurysm and dissection and the need for closely monitoring aortic size highlight the importance of establishing the diagnosis of Marfan syndrome.

... / ... Lire la suite

(???)

The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes  Voir?

Type 2 diabetes is a disease involving both inadequate insulin levels and increased glucagon levels. While glucagon and insulin work together to achieve optimal plasma glucose concentrations in healthy individuals, the usual regulatory balance between these 2 critical pancreatic hormones is awry in patients with diabetes. Although clinical discussion often focuses on the role of insulin, glucagon is equally important in understanding type 2 diabetes. Furthermore, an awareness of the role of glucagon is essential to appreciate differences in the mechanisms of action of various classes of glucose-lowering therapies.

... / ... Lire la suite

(???)

Change in Submaximal Cardiorespiratory Fitness and All-Cause Mortality  Voir?

To evaluate the relationship between change in submaximal cardiorespiratory fitness (sCRF) and all-cause mortality risk in adult men and women.
(???)

Aortic Root Dilation: Do Patients With Marfan Syndrome Fare Worse Than Those With Marfanoid Features?  Voir?

To discover whether patients with aortic root dilation and leptosomic features but without a diagnosis of Marfan syndrome (MFS) fare similarly to patients with MFS.
(???)

The Diagnostic Accuracy of Fractional Exhaled Nitric Oxide Testing in Asthma: A Systematic Review and Meta-analyses  Voir?

To evaluate the diagnostic accuracy of fractional exhaled nitric oxide (FeNO) measurement in individuals with suspected asthma.
(???)

67-Year-Old Woman With an Adrenal Mass  Voir?

A 67-year-old woman presented to the emergency department with a 2-day history of right-sided flank pain. A noncontrast abdominal computed tomography (CT) scan revealed a partially obstructing right ureteral calculus. Incidentally found on noncontrast CT was a 2.7-cm right-sided adrenal mass that measured 15 Hounsfield units (HU), appeared homogenous and round, had smooth borders, and did not have calcifications or necrotic areas. The patient had no prior cross-sectional imaging for comparison. She spontaneously passed the kidney stone, with resolution of her pain.

... / ... Lire la suite

(???)

79-Year-Old Woman With Jaundice and Anemia  Voir?

A 79-year-old woman was referred by her primary care physician to the emergency department for evaluation and management of a 2-week history of jaundice, bilateral leg edema, and increased dyspnea. A complete blood count (CBC) obtained by her primary care physician was remarkable (reference ranges provided parenthetically) for a hemoglobin level of 5.8 g/dL (12.0-15.5 g/dL), which had decreased from 11.0 g/dL 4 months before presentation. She reported a 2-month history of intermittent right upper-quadrant pain, generalized weakness, fatigue, increased urinary frequency, decreased appetite, and subjective fevers and chills.

... / ... Lire la suite

(???)

23-Year-Old Man With Jaundice and Elevated Liver Enzymes  Voir?

A 23-year-old man presented to an outside hospital with a 3-day history of dark-colored urine, yellow discoloration of the eyes, and pain in the chest and lumbar area. He denied having confusion, fever, chills, or light-colored stools. He reported consuming small amounts of alcohol once a month and never using tobacco or illicit drugs. His medical history was positive only for anxiety, which was not treated pharmacologically. The patient stated that he had not taken nonprescription medications, herbal supplements, or prescribed medication in the preceding year.

... / ... Lire la suite

(???)

61-Year-Old Woman With Episodic Dysphagia and Chest Pain  Voir?

A 61-year-old woman presented to an outpatient clinic with an 18-month history of episodic dysphagia and chest pain. She described several nonprogressive episodes of dysphagia related to solid food only and associated with sharp, nonradiating, lower retrosternal pain. On each occasion, the symptoms resolved when she regurgitated partially digested food. She reported no oropharyngeal dysphagia, such as nasopharyngeal regurgitation or difficulty initiating swallowing, odynophagia, history of aspiration, melena, weight loss, fevers, chills, or altered bowel habits.

... / ... Lire la suite

(???)

Relationship Between Obesity and Survival in Patients Hospitalized for Hypertensive Emergency  Voir?

Recently in Mayo Clinic Proceedings, Carbone et al1 discussed the obesity paradox in patients with heart failure, and we have also discussed this paradox in patients hospitalized with pulmonary hypertension.2 In fact, despite the clear association of obesity and increased cardiovascular disease (CVD), obese patients have also been reported to have paradoxical lower mortality, referred to as the “obesity paradox,” in CVD conditions such as coronary heart disease, heart failure, peripheral arterial disease, atrial fibrillation, and hypertension (HTN).

... / ... Lire la suite

(???)

Cardiorespiratory Fitness and Health Outcomes: A Call to Standardize Fitness Categories  Voir?

An inverse association between physical activity or fitness status and health outcomes has been reported by several cohort studies. When fitness categories are established in quartiles or quintiles based on the peak exercise capacity achieved, the association is graded. Although significant health benefits of increased cardiorespiratory fitness (CRF) have been uniformly reported, the degree of protection has varied substantially between studies. This variability is likely due to varying methods used to define CRF categories, and not considering age, despite its strong effect on CRF.

... / ... Lire la suite

(???)

Highlights from the Current Issue – Audiovisual Summary  Voir?

Karl A. Nath, MBChB, Editor-in-Chief of Mayo Clinic Proceedings, discusses the Editor's Choice and Highlights articles appearing in the February 2018 issue.
(???)

General Information  Voir?

(???)

Table of Contents  Voir?

(???)

Editorial Board  Voir?

(???)

Water Lily, Black-eyed Susan, Fern by Yulia Hanansen  Voir?

Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author.

... / ... Lire la suite

(???)

Mucinous Neoplasm of the Appendix and Pseudomyxoma Peritonei  Voir?

This image shows a mucinous neoplasm replacing the appendix, extending through the wall of the appendix, causing mucin accumulation in the peritoneum with extensive involvement of the serosa and omentum.
(???)

Diagnosis and Management of Headache in Older Adults  Voir?

Headache is a common, disabling neurologic problem in all age groups, including older adults. In older adults, headache is most likely a primary disorder, such as tension-type headache or migraine; however, there is a higher risk of secondary causes, such as giant cell arteritis or intracranial lesions, than in younger adults. Thus, based on the headache history, clinical examination, and presence of headache red flags, a focused diagnostic evaluation is recommended, ranging from blood tests to neuroimaging, depending on the headache characteristics.

... / ... Lire la suite

(???)

Evidence, Not Evangelism, for Dietary Recommendations  Voir?

The conundrum about what and how much to eat is a uniquely human predicament. Every other free-living animal on Earth eats and drinks according to instincts that compel them to consume the diet for which they are genetically adapted—which ensures optimal nutrition. We have similar intuitive abilities, and in fact, indigenous humans living in the wild generally do not develop obesity, diabetes, hypertension, coronary artery disease, or the other chronic noncommunicable diseases prevalent in modern societies.

... / ... Lire la suite

(???)

Proton Pump Inhibitors: Review of Emerging Concerns  Voir?

First introduced in 1989, proton pump inhibitors (PPIs) are among the most widely utilized medications worldwide, both in the ambulatory and inpatient clinical settings. The PPIs are currently approved by the US Food and Drug Administration for the management of a variety of gastrointestinal disorders including symptomatic peptic ulcer disease, gastroesophageal reflux disease, and nonulcer dyspepsia as well as for prevention of gastrointestinal bleeding in patients receiving antiplatelet therapy.

... / ... Lire la suite

(???)

In Reply—Diaphragmatic Pacemaker for Perry Syndrome  Voir?

We thank Drs Konno and Wszolek for their comments and insights on our review of current implantable neurostimulation devices to treat neurologic disorders. Their presented work using a phrenic neurostimulation device to treat Perry syndrome is extremely exciting and highlights the potential for neuromodulation treatment in a broad range of disorders across many symptoms. Their work also highlights a very important aspect of emerging neurostimulation therapies, in the summative and long-term response that they observed in this study.

... / ... Lire la suite

(???)

Diaphragmatic Pacemaker for Perry Syndrome  Voir?

We read with a great interest the excellent article by Edwards et al1 in the September 2017 issue of Mayo Clinic Proceedings. The authors elegantly reviewed the current knowledge of neurostimulation devices clinically used for neurologic disorders. These devices included deep brain stimulation, motor cortex stimulation, responsive neurostimulation, spinal cord stimulation, and vagus nerve stimulation. The authors described clinical indications for each device in detail as well as historical aspects of device development.

... / ... Lire la suite

(???)

A Stony Gland!  Voir?

A 35-year-old man presented with a swelling below the jaw on the right side. The swelling increased on taking food. On examination, a 3 × 3 cm firm swelling was seen in the right submandibular region (Figure 1). The swelling was bidigitally palpable. The computed tomography scan of the swelling revealed an enlarged submandibular gland with dense white opacities suggestive of multiple stones (Figure 2). A diagnosis of submandibular sialolithiasis was made and the gland was removed surgically. The patient was asymptomatic at 4-month follow-up.

... / ... Lire la suite

(???)

Dernière mise à jour : 21/02/2018 : 11:50


Préférences

Se reconnecter :
Votre nom (ou pseudo) :
Votre mot de passe
Captcha reload
Recopier le code :


  Nombre de membres 413 membres
Connectés :
( personne )
Snif !!!
Lettre d'information
Pour avoir des nouvelles de ce site, inscrivez-vous à notre Newsletter.
Captcha reload
Recopier le code :