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Sommaires des Revues - Word Neurosurgery

World Neurosurgery

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Spontaneous Intrauterine Depressed Skull Fractures: Report of Two Cases Requiring Neurosurgical Intervention and Literature Review  Voir?

Spontaneous intrauterine depressed skull fractures (IDSF) are rare fractures that often require neurosurgical evaluation and therapy. The majority of reported congenital depressions are secondary to maternal abdominal trauma or instrumentation during delivery. Spontaneous IDSF occur in the setting of uneventful normal spontaneous vaginal delivery (NSVD) or cesarean section, without obvious predisposing risk factors. The etiology and optimal management of spontaneous IDSF remain controversial.

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The Extra-Cranial Consequences of Sub-Arachnoid Haemorrhage  Voir?

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Symptomatic Vasospasms as a life-threatening complication after transsphenoidal surgery  Voir?

To identify symptomatic vasospasms as a rare complication after pituitary surgery with emphasis on management and outcome.
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Efficacy of cone beam computed tomography in treating cavernous sinus dural arteriovenous fistula  Voir?

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Surgery for herniated lumbar disc in daily tobacco smokers: A multicenter observational study  Voir?

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Prognostic factors in skull base chordoma: a systematic literature review and meta-analysis  Voir?

Currently, there are still lack of reviews assessing the complete range of prognostic factors in skull base chordoma (SBC). This study aimed to systematically review the published literature on prognostic factors in SBC and to establish pooled hazard ratios (HRs) of such factors.
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First Depiction of Flow Voids to Differentiate Pituicytomas from Giant Adenomas  Voir?

Pituicytomas are rare low-grade glial lesions of neurohypophysis or adenohypophysis. They are often misdiagnosed as adenomas due to their similar morphology. Previous reports have underlined their non specific aspect. In our experience, presence of flow voids on MR, which usually indicate hypervascularized tumors with strong arterial supply, may be a useful sign to identify pituicytomas. Unlike adenomas, pituicytomas are highly vascularized tumors. Second, we emphasize the strong enhancement of these tumors when compared to normal hypophysis, which may be another sign of the their hypervascularization.

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The First Experience of Triple Nerve Transfer in Proximal Radial Nerve Palsy  Voir?

Injury to distal of posterior cord of brachial plexus leads to palsy of the radial and axillary nerves. The symptoms are usually motor deficits of the deltoid muscle, triceps brachii muscle, and the extensor muscles of the wrist, thumb and fingers. Tendon transfers, nerve grafts, and nerve transfers are options of surgical treatment of proximal radial nerve palsy to restore some motor functions. Tendon transfer is painful, requires a long immobilization, and decreases donor muscle strength; nevertheless, nerve transfer produces promising outcome.

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Primary Diffuse Large B-Cell Lymphoma in a patient with Rubinstein-Taybi Syndrome: case report and review of literature  Voir?

Rubinstein-Taybi syndrome (RSTS) is a rare, congenital syndrome that is known to be associated with neoplasms of various organ systems. Evaluation and treatment of such patients is challenging given the cognitive delay and heterogeneity of pathological presentations that define this syndrome.
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The relevance of Simpson grade resectionsin the modern neurosurgical treatment of World Health Organization Grade 1, 2, and 3meningiomas  Voir?

The Simpson grading system has played an important role in the surgical resections of meningiomas. This study set out to determine if this grading system predicts meningioma recurrence in a modern cohort of patients with tumors of all World Health Organization (WHO) grades.
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Neurosurgical Resident Error: A Survey of U.S. Neurosurgery Residency Training Program Directors’ Perceptions  Voir?

Efforts to address resident errors and enhance patient safety have included systemic reforms such as the ACGME’s mandated duty-hour restrictions and specialty-specific initiatives such as the neurosurgery Milestone Project. However, there is currently little data describing the basis for these errors or outlining trends in neurosurgical resident errors.

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Postoperative Intravenous Acetaminophen for Craniotomy Patients: A Randomized Controlled Trial  Voir?

To determine whether opioids during the first 24 postoperative hours were significantly altered when receiving intravenous (IV) acetaminophen during that time compared to those receiving placebo (normal saline).
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Ruptured Persistent Trigeminal Artery Causing Direct Cavernous Sinus Fistula Treated with Pipeline Embolization and Minimal Coiling  Voir?

Rupture of a persistent trigeminal artery associated with development of a cavernous sinus fistula in a traumatic setting is rare. They are typically treated with coil embolization of the cavernous sinus.
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Rare giant prevertebral thoracic myelomeningocele  Voir?

Here we report a 72-year-old man who presented with complaint of sudden onset weakness and impaired sensation in the left lower extremity. Radiographic evaluation revealed a congenital malformation with multiple formation defects including a giant thoracic prevertebral myelomeningocele. Following microsurgical dethetering of the spinal cord the patient recovered ambulation with assist. While thoracic myelomeningoceles are themselves rare, in this case the patient presented at a late age, and responded well to conservative management.

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Citizens Urge FDA to Restrict High-Potency Opioids  Voir?

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Supraorbital Approach for Resection of Clinoidal Meningioma  Voir?

Meningiomas of the clinoid region pose formidable surgical challenge. Pterional craniotomy is the traditional approach, and often associated with high-risk post-surgical morbidities. In the current presentation, we describe an elderly male with a clinoidal meningioma that underwent a minimally invasive supra-orbital craniotomy for tumor resection. Patient presentation, neuroimaging, and surgical techniques (patient position, incision, anatomical consideration, and surgical steps) are described meticulously.

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Optical coherence tomography in the management of skull base fibrous dysplasia with optic nerve involvement  Voir?

Fibrous dysplasia (FD) of the skull base can present with optic nerve compression. As most patients initially do not experience vision loss, controversy exists whether to proceed with prophylactic surgical decompression or elect for conservative observation. Optical coherence tomography (OCT), a physiologic imaging modality widely used to assess the condition of the retinal nerve fiber layer (RNFL), has been useful in monitoring compressive tumors on the optic nerve. The present study evaluated the potential use of OCT in the management of FD patients with optic nerve involvement.

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Predictors of postoperative recovery based on Health-related Quality-of-Life in patients after Degenerative Lumbar Scoliosis Surgery  Voir?

To investigate the factors associated with the recovery process of elderly patients following degenerative lumbar scoliosis surgery.
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Outcomes of Two Isocenter Gamma Knife radiosurgery for typical trigeminal neuralgia patients: pain response and quality of life  Voir?

To evaluate the effectiveness and safety of two isocenter GKS by reviewing TN patients of last ten years.
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Proposed treatment paradigm for intracranial chondrosarcomas based on multidisciplinary coordination  Voir?

There was no consensus regarding the treatment of intracranial chondrosarcoma (CSA). The study aimed to evaluate the adverse factors for progression-free survival (PFS) and overall survival (OS), and propose a treatment strategy for CSA.
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Evolution of prophylaxis protocols for venous thromboembolism in neurosurgery: results from a prospective comparative study on low-molecular weight heparin, elastic stockings and intermittent pneumatic compression devices  Voir?

The incidence of venous thromboembolism (VT) in neurosurgical practice is astonishingly high representing a major cause of morbidity and mortality. Prophylaxis strategies include elastic stockings (ES), low-molecular weight heparin (LMWH) and intermittent pneumatic compression (IPC) devices.
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Radiosurgery for Treatment of Renal Cell Metastases to Spine: A Systematic Review of the Literature  Voir?

The incidence of renal cell carcinoma (RCC) continues to rise, and the spine is the most common site for bony metastasis. Radiation therapy is one treatment for spinal RCC metastasis. Stereotactic body radiotherapy (SBRT) is a newer treatment that reportedly has benefits over conventional external beam radiotherapy (cEBRT). This study systematically reviewed the current literature on SBRT for metastatic RCC to spine.

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Reversible Parkinson-Like Symptoms in a Patient with Bilateral Chronic Subdural Hematomas and Cervical Spinal Stenosis  Voir?

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A stent-retrieving into an aspiration catheter with proximal balloon (ASAP) technique: A technique of mechanical thrombectomy  Voir?

The best technique for the first attempt at mechanical thrombectomy for acute ischemic stroke is a still matter of debate. In this study, we evaluated the efficacy of a stent-retrieving into an aspiration catheter with proximal balloon (ASAP) technique that employs a series of thrombus extraction by withdrawing the stent retriever into the aspiration catheter, and continuous aspiration from the aspiration catheter in the first attempt.

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Is vertebral column resection (VCR) necessary in correcting severe and rigid thoracic kyphoscoliosis - A single-institution surgical experience  Voir?

Three-column spinal osteotomies were developed to address severe and stiff kyphoscolisis. However, the optimal choice of osteotomy in these patients is still unclear. This retrospective study aims to compare the outcomes and complications between grade 4 and grade 5 osteotomies in patients with severe and stiff thoracic kyphoscoliosis.

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Management of through-and-through penetrating skull injury: a railroad stake that transgressed the anterior skull base  Voir?

Penetrating injuries involving foreign objects that transgress the entirety of the human skull presents challenges in the management of vascular injuries, infectious risk, cerebrospinal fluid leak, and cosmetic repair. Ultimately, effective management of these injuries requires a multi-disciplinary team and judicious surgical planning. Here we present the management of a patient who suffered a penetrating injury from a railroad stake, with entry and exit points involving left and right anterior aspect of the temporal fossa, respectively.

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Progressive functional underdrainage in CSF shunt dependent women during pregnancy. Case report and review of the literature  Voir?

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The Effects of Red Blood Cell Transfusion on Functional Outcome after Aneurysmal Subarachnoid Hemorrhage  Voir?

The optimal red blood cell transfusion (RBCT) trigger for patients with aneurysmal subarachnoid hemorrhage (SAH) is unknown. In patients with cerebral vasospasm, anemia may increase susceptibility to ischemic injury; conversely, RBCT may worsen outcome given known deleterious effects.
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Preoperative Prediction of the Necessity for Anterior Clinoidectomy during Microsurgical Clipping of Ruptured Posterior Communicating Artery Aneurysms  Voir?

Although most posterior communicating artery (PCoA) aneurysms can be clipped easily with excellent results, some require anterior clinoidectomy for safe and complete clipping.
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The Hypoglossal Nerve: Anatomical Study Of Its Entire Course  Voir?

Only a few anatomic studies concerning the entire course of the hypoglossal nerve (cranial nerve XII) have been reported. The purpose of the present study is to analyze all the relationships of the XII nerve with the surrounding structures from the brainstem to the tongue through a microscopic perspective. A comprehensive anatomically and clinically oriented classification of its different segments is proposed.

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Emergency extracranial-intracranial bypass to revascularize salvageable brain tissue in acute ischemic stroke patients  Voir?

To present an algorithm based on clinical and radiological factors including MR perfusion/diffusion mismatch (MR-PDM) for the indication of urgent cerebral bypass in patients with acute ischemic stroke
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Electodiagnostic and Advanced Neuro-imaging Characterization for Successful Treatment of a Spinal Extradural Arachnoid Cyst  Voir?

Spinal extradural arachnoid cysts (SEAC) are relatively uncommon. However, several large cysts have presented with spinal cord compression requiring surgical intervention.
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"Spontaneous Fusion of S2/S3 Spondyloptosis in an Adult: A Case Report"  Voir?

Spondyloptosis is grade V on the Meyerding classification. Traumatic spondyloptosis can occur throughout the spinal column, particularly at junctional levels, and finding the ideal surgical strategy to address it remains a challenge for spinal surgeons. The sacrum is considered a united bone in adults and sacral inter-segmental spondyloptosis is extremely rare. Herein, we present a very unusual case of S2/S3 spondyloptosis in a 27-year-old female patient with spontaneous solid fusion and we discuss the relevant literature.

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Unilateral C1 Sagittal Split Fractures: An Unusual Entity Revisited  Voir?

An isolated, unilateral fracture of the C1 lateral mass is a rare condition that has been only minimally described in the literature. Historically, these fractures have predominantly been managed conservatively with either external immobilization or traction.
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Elevation of Proenkephalin 143-183 in Cerebrospinal Fluid in Moyamoya Disease  Voir?

In moyamoya disease (MMD), the causes of differences in clinical features between children and adults and of the dramatic temporal changes in moyamoya vessels are poorly understood. We previously discovered elevated levels of m/z 4588 and m/z 4473 peptides in cerebrospinal fluid (CSF) in MMD patients. This study examined the amino acid sequences of these peptides and quantified in specimens.

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Pattern of closure of skull base synchondroses in Crouzon syndrome  Voir?

The age of closure of skull base synchondroses has never been analyzed in a homogenous population of children with Crouzon syndrome.
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Clinical Presentation, Diagnosis, and Surgical Treatment of Spontaneous Cervical Intradural Disc Herniations: A Review of the Literature  Voir?

Spontaneous cervical intradural disc herniation (IDH) is a rare occurrence with limited and disparate information available regarding its presentation, diagnosis, and treatment. However, its accurate detection is vital for planning surgical treatment. In this review of the literature, we collected data from all cervical intradural disc herniations described to date. Particular attention is paid to diagnostic findings, surgical approach and causation for cervical IDH, especially at the cervicothoracic junction.

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Cranial Base Meningiomas  Voir?

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Syrinx to subarachnoid shunting for syringomyelia  Voir?

Surgery for syringomyelia generally aims to treat the underlying cause, if it is known. Optimal management is unclear for idiopathic syringomyelia, or where treatment of the putative cause has failed or is high risk. Syrinx to subarachnoid shunting is an option for these cases; a series is reported to assess the outcomes of this approach.

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Suturing treatment for blood blister–like aneurysm in the supraclinoid segment of the internal carotid artery  Voir?

Blood blister–like aneurysms (BBAs) are rare but very dangerous and challenging to treat. Recurrence and rebleeding are often reported, and many neurosurgeons and interventional radiologists are discouraged by such poor outcomes. Currently, there is no standard method to treat this type of aneurysm. We describe 5 cases of ruptured BBAs in the supraclinoid segment of the internal carotid artery, which were treated successfully using a suturing technique. No patient experienced recurrence or rebleeding, and all patients had a good prognosis.

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Outcomes after Transcranial and Endoscopic Endonasal Approach for Tuberculum Meningiomas - a retrospective Comparison  Voir?

Degree of resection and visual outcome are the main concerns in the surgical resection of tuberculum sellae meningioma (TSM). In addition to the transcranial approach (TCA), the endoscopic endonasal approach (EEA) has been increasingly used. However, the controversy regarding the optimal surgical approach is not clearly resolved.

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Analogous 3D CISS sequences enhance the utility of 3D TOF MRA in delineating lenticulostriate arteries in insular gliomas: evidence from a prospective clinico-radiological analysis of 48 patients  Voir?

3D TOF imaging is the current gold standard for non-invasive, preoperative localization of the lenticulostriate arteries (LSAs) in insular gliomas. The utility of this modality is, however, tumour-intensity dependant.
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Predisposing factors of fracture nonunion after posterior C1 lateral mass screws combined with C2 pedicle/laminar screws fixation for type II odontoid fracture  Voir?

The aim of this study was to explore the predisposing factors for fracture nonunion after C1 lateral screw combined with C2 pedicle/laminar screw for type II odontoid fracture, and hope to provide references in decision making and surgical planning for spinal surgeons.
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Superficial Siderosis Associated with a Pineal Cavernous Malformation  Voir?

Cavernous malformations in the pineal region are very rare and are difficult to anticipate from preoperative evaluation in patients with pineal apoplexy. We herein report the first case of a pineal cavernous malformation with superficial siderosis. Radiological findings were helpful in identifying the presence of the cavernous malformation.

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Prolonged Intracisternal Papaverine Toxicity: index case description and proposed mechanism of action  Voir?

Intracisternal papaverine (iPPV) is a vasodilator used for prophylaxis of intra-operative vasospasm during aneurysmal clipping. Its post-operative side effects include transient cranial nerve palsies, most commonly mydriasis due to oculomotor nerve involvement with rapid resolution. We critically review the current literature on the adverse effects of iPPV in aneurysmal surgery, with a focus on oculomotor nerve involvement. In addition, this manuscript portrays the index case of prolonged bilateral mydriasis secondary to iPPV irrigation toxicity and its putative underlying mechanism.

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Transdural spinal cord herniation: tips and tricks  Voir?

Recognition of transdural spinal cord herniation has increased over the past decade. This condition remains little known, particularly outside the specialized fields of spinal surgery and neuroradiology, leading to a significant delay in clinical diagnosis and treatment. It should be considered among the differential diagnoses in patients with gradual-onset lower-limb weakness of presumed spinal origin. Reaching a diagnosis using MRI is essential to refer patients for surgery before their myelopathy worsen.

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Endoscopic transsphenoidal surgery outcomes in 331 nonfunctioning pituitary adenoma cases following a single surgeon learning curve  Voir?

The outcomes of recent endoscopic surgery of nonfunctioning pituitary adenomas (NFPAs) were controversial when compared to traditional microscopic surgery. We aimed to assess the outcomes of endoscopic transsphenoidal surgeries performed by one surgeon with 7 years of experience and elucidate the predictive factors for surgical outcomes for NFPAs.

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Delayed Complications After Transsphenoidal Surgery for Pituitary Adenomas  Voir?

Perioperative complications after transsphenoidal surgery for pituitary adenomas have been well documented in the literature; however, some complications can occur in a delayed fashion postoperatively and reports are sparse about their occurrence, management, and outcome. Here, we describe delayed complications after transsphenoidal surgery and discuss the incidence, temporality from the surgery, and management of these complications based on the findings of studies that reported delayed postoperative epistaxis, delayed postoperative cavernous carotid pseudoaneurysm formation and rupture, vasospasm, delayed symptomatic hyponatremia (DSH), hypopituitarism, hydrocephalus, and sinonasal complications.

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Cerebrospinal Fluid Leak at Percutaneous Exit of Ventricular Catheter as Crucial Risk Factor for External Ventricular Drainage-Related Infection in Adult Neurosurgical Patients  Voir?

The placement of a ventricular catheter for temporary cerebrospinal fluid (CSF) diversion is associated with a considerable risk of CSF infection. The authors investigated the effect of a CSF leak on CSF-related infection and the predisposing factors for a CSF leak.
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Preoperative navigated transcranial magnetic stimulation and tractography to guide endoscopic cystoventriculostomy: A technical note and case report  Voir?

To report a technique for endoscopic cystoventriculostomy guided by preoperative navigated transcranial magnetic stimulation (nTMS) and tractography in a patient suffering from a large speech eloquent arachnoid cyst.
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Supraorbital keyhole approach to the sella and anterior skull base via a forehead wrinkle incision  Voir?

The aim of this study was to evaluate the safety and effectiveness of the supraorbital keyhole approach to the sella and anterior skull base via a forehead wrinkle incision.
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Identification of Driver Genes and Key Pathways of Glioblastoma Demonstrates JNJ-7706621 as a novel Anti-Glioblastoma Drug  Voir?

The aim of this study is to identify novel targets of diagnosis, therapy and prognosis for glioblastoma, as well as to verify the therapeutic effect of JNJ-7706621 regarding to glioblastoma.
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Novel application of time-spatial labeling inversion pulse magnetic resonance imaging for diagnosis of external hydrocephalus  Voir?

Although a subdural fluid collection is frequently observed, diagnostic methods that differentiate between the subdural collection caused by external hydrocephalus and that caused by subdural hygroma have not been established. Here, we report a case of external hydrocephalus caused by Gliadel-induced eosinophilic meningitis that has been previously reported in only one case and can be diagnosed by time-spatial labeling inversion pulse magnetic resonance imaging (Time-SLIP MRI).

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Individual variability of the human cerebral cortex identified using intraoperative mapping  Voir?

The intraoperative functional cortical mapping using direct electrical stimulation may show a wider individual variability than those suggested by non-invasive imaging data on healthy subjects.
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Reappraisal of neonatal greenstick skull fractures caused by birth injuries: Comparison of 3-dimensional reconstructed computed tomography and simple skull x-rays  Voir?

The most common birth-associated head injuries during vaginal delivery are cephalhematomas and subgaleal hematomas, and cranial injuries are rarely encountered. The neonate cranium is soft and pliable, and greenstick skull fractures (GSFs) are expected to be more frequent than linear or depressed fractures, but are extremely difficult to detect by simple skull x-ray (SSXR), and as a result, no reports have been issued on this topic to date. Recent reports suggest that technological advances in 3-dimensional reconstructed computed tomography (3DCT) have successfully enhanced the diagnostic accuracy for cranial fractures.

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Modular classification of endoscopic endonasal transsphenoidal approaches to the sellar region: anatomical quantitative study  Voir?

Endoscopic visualization does not necessarily correspond to an adequate working space. The need of balancing invasiveness and adequacy of sellar tumor exposure has recently led to the description of multiple endoscopic endonasal transsphenoidal approaches. Comparative anatomical data on these variants are lacking.

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Comparison of Quality Metrics for Pediatric Shunt Surgery and Proposal of the Negative Shunt Revision Rate  Voir?

Shunt surgery is common in pediatric neurosurgery and is associated with relevant complication rates. We sought to compare previously published metrics in a single data set and propose the Negative Shunt Revision Rate (NSRR) as a new quality metric, defined as the proportion of shunt explorations revealing a properly working system.

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Severe subarachnoid hemorrhage due to a fusiform lateral anterior (A1) artery perforator aneurysm with “spontaneous resolution”  Voir?

Perforating arteries are thin and long vessels which originate from the main cerebral arteries. Subarachnoidal hemorrhage from a perforator aneurysm is rare. Here, we report on a 70-year-old woman who presented with severe subarachnoid hemorrhage from a fusiform lateral anterior (A1) artery perforator aneurysm. Unexpectedly, digital subtraction angiography was non-diagnostic. MR imaging, however, demonstrated occlusion of the aneurysm secondary to thrombosis. Surgery was performed to remove the associated hematoma, and histopathological examination verified intraaneurysmal thrombosis.

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Surgery and radiotherapy for symptomatic spinal metastases is more cost effective than radiotherapy alone: a cost utility analysis in a UK spinal center  Voir?

Surgery for symptomatic spinal metastases is effective at prolonging ambulation and life, but may appear costly at first glance. We have studied the difference between the cost of surgery and reimbursement received, as well as the cost-effectiveness of surgery in a UK tertiary referral spinal center.

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Comparison of chronic Dysphagia in Standalone versus Conventional Plate and Cage Fusion  Voir?

Standalone cages have gained popularity due to their ease of implantation, reduced operating time, and lower profile compared to traditional plate and cage systems. The aim of this study was to compare the risk of chronic dysphagia among those who undergo ACDF with traditional plating techniques versus standalone systems.

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Recurrent Cerebral Hemorrhages In Normal Pregnancy Secondary to Mycotic Pseudoaneurysms Related to Choriocarcinoma  Voir?

Choriocarcinoma coexisting with or after normal pregnancy is extremely rare. To our knowledge, our case report is the first time cerebral mycotic pseudoaneurysms from choriocarcinoma have been proven angiographically.
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Suturing and dural wrapping for a blood blister-like aneurysm on the supraclinoid segment of the ICA due to dissection  Voir?

Internal carotid artery (ICA) reconstruction is still the most effective treatment for a blood blister-like aneurysm (BBA) on the supraclinoid segment of the ICA, and clipping after wrapping has the most precise effects. However, the materials used are most often artificial. This study examined the use of autologous dura to replace the artificial materials used for wrapping after suturing a BBA.

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Surgical management of giant intracranial meningioma: operative nuances, challenges and outcome  Voir?

The giant intracranial meningioma [GIM] constitutes a different spectrum of brain tumors which invade the vital neurovascular structures and makes the primary mode of treatment, surgery, a technically challenging one. The surgery of GIM is unique due to its large size, prominent vascularity, entangling and limited visualisation of various neurovascular structures and severe cerebral edema. The study reports the authors surgical experience of 80 GIM cases, the operative challenges and surgical outcome.

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The endoscopic buccal fat pad flap for closure of skull base defects: a report of five cases  Voir?

To demonstrate the clinical utility of the buccal fat pad to close a variety of skull base defects.
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Prevention and Treatment for Hyponatremia in Patients with Subarachnoid Hemorrhage: A Systematic Review  Voir?

Current guidelines have not systematically assessed the literature for the management of hyponatremia in patients with subarachnoid hemorrhage.
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Extraforaminal discal cyst as a cause of radiculopathy  Voir?

We report the first extraforaminal location of a lumbar discal cyst. The patient was treated by hemilaminectomy, arthrectomy, cyst resection and unilateral arthrodesis, achieving complete release of the nerve root. Extraforaminal lumbar discal cyst may represent an unexpected cause of sciatic pain with favorable outcome after surgical resection.

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Contact Aspiration with the New ARC™ Catheter for Thrombectomy of Acute Ischemic Stroke: A Single Center Results  Voir?

Contact aspiration has gained growing acceptance in the endovascular stroke therapy. The safety and efficacy data of the novel ARC™ catheter (Medtronic, Irvine, CA) used for intracranial thrombectomy was poorly evaluated. We reported our preliminary results with the ARC™ with regard to angiographic reperfusion, duration of thrombectomy, safety, and clinical outcome at 90 days.

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Early hemodynamic changes based on initial color-coding angiography as a predictor for developing subsequent symptomatic vasospasm after aneurysmal SAH  Voir?

Prediction of vasospasm following aneurysmal subarachnoid hemorrhage (aSAH) remains imperfect and currently relies on clinical and radiographic characteristics. Whether early hemodynamic changes may refine risk stratification for delayed vasospasm (DV) after aSAH was analyzed.
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WHO grade II meningiomas: the role of adjuvant/salvage Gamma Knife surgery after initial surgery and prognostic factor assessment  Voir?

This study was performed to evaluate the efficiency of gamma knife surgery (GKS) on reducing recurrence for World Health Organization (WHO) grade II meningiomas after surgery, and to define the risk factors associated with tumor recurrence/progression and patient’s death.
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Successful surgical resection of spinal artery aneurysms: Report of three cases  Voir?

Spinal artery aneurysms (SAAs) are extremely rare lesions that can occur in isolation or associated with vascular malformations. Herein, we present three unusual cases of SAAs, and discuss imaging, diagnosis and surgical management strategies.
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Mikulicz’s disease mimicking intraorbital tumors  Voir?

We report a case of Mikulicz’s disease (MD), an immunoglobulin G4 (IgG4)-related disease that affects the lacrimal and salivary glands. IgG4-related disease is a relatively new clinical entity, and not commonly encountered by neurosurgeons. MD sometimes mimics intraorbital tumors such as malignant lymphoma, but responds well to corticosteroid treatment. Thus, it is important to recognize the clinical and radiographic features of MD.

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Factors Associated with 90-Day Outcomes of Patients with Acute Posterior Circulation Stroke Treated By Mechnical Thrombectomy  Voir?

Early recanalization of acute posterior circulation stroke due to large intracranial vessel occlusion by mechanical thrombectomy with stent retrievers may improve the outcome of patients. However, evidence of patient selection is still lacking. The study investigated the prognostic factors of acute posterior circulation stroke due to large intracranial arterial occlusion when treated withstent retriever thrombectomy.

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Post Natal Management of Myelomeningocele: Outcome with a Multidisciplinary Team Experience  Voir?

Myelomeningocele (MMC) is a complex neural tube defect. Few studies report the results of modern post-natal management. The goal of this study was to report the long term outcome of a multidisciplinary approach of MMC patients.
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Orbital compartment syndrome after frontotemporal craniotomy: case report and review of literature  Voir?

Orbital compartment syndrome (OCS) is a rare condition characterized by increased intraorbital pressure and hypoperfusion of critical neural structures and usually associated with external ophthalmoplegia. We report a case of postoperative OCS following a frontotemporal craniotomy and review pertinent literature.

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Agenesis of the Anterior Falx Cerebri in a Patient with Planned Interhemispheric Approach to a Third Ventricle Mass  Voir?

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Physiologic Growth Hormone Replacement Therapy and Craniopharyngioma Recurrence in Pediatric Patients: A Meta-Analysis  Voir?

A systematic review and meta-analysis were conducted to examine the effect of growth hormone replacement therapy (GHRT) on the recurrence of craniopharyngioma in children.
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Postoperative cerebral ischemia due to hypotension in a moyamoya patient with autonomic dysfunction: A case report  Voir?

Hypotension is a significant risk factor for the development of ischemic complication following revascularization surgery for moyamoya disease (MMD). However, it is currently unknown whether autonomic dysfunction also plays a role.
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Training of intra-axial brain tumor resection using a self-made simple device with agar and gelatin  Voir?

Self-made devices composed of agar and gelatin gel have been used for resident training of intra-axial brain tumor resection. The mixture gel of agar and gelatin is retractable and can be suctioned. Hardness of the gel depends on the concentration of the solution. Therefore, by changing the concentration, it is easy to make gels of various hardness. In this study, a mass of gel that looked like a tumor was put into another gel that looked like the brain. A part of the “brain” was regarded as the eloquent area.

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Intracranial Meningioma in patients younger than 35 years of age: An evolution of the disease in the Era of Human Immunodeficiency Virus infection. A retrospective observational study  Voir?

Intracranial meningiomas are more common among patients in their 5th-7th decades of life and rare in children and early adulthood. They constitute between 1.5% of all neoplasms in patients younger than 20 years of age but account for 13.5% of all neoplasms in patients aged between 20-34 years. They are often associated with hereditary or familial syndromes in pediatrics and young adults and tend to be of high grade.

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Contralateral Approach to Middle Cerebral Artery Aneurysms: An Anatomical-Clinical Analysis to Improve Patient Selection  Voir?

A contralateral approach to clip a middle cerebral artery (MCA) aneurysm in case of bilateral intracranial aneurysms reduces surgical time and cost. However, there is a lack of evidence for objective patient selection. In this study, we assessed the change in surgical freedom along the contralateral MCA to provide objective evidence for patient selection.

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Subtemporal approach for gross total resection of retrochiasmatic craniopharyngiomas – our experience on 30 cases  Voir?

Surgical treatment of retrochiasmatic craniopharyngiomas is associated with higher rates of complications, mortality, failure of complete removal, and recurrence when compared to craniopharyngiomas located elsewhere. These tumors lie behind the optic chiasm and, when large, can extend upward into the third ventricle and downward along the brain stem making their adequate exposure challenging. Most of the proposed techniques either employ a trans lamina terminalis route or require wide bony exposures.

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Quality and quantity of memories in patients who underwent awake brain tumor resection  Voir?

Awake craniotomy is performed with increasing frequency for brain tumor surgery in eloquent areas. However, little is known about patient’s memories of this procedure. Therefore, we retrospectively analyzed quality and quantity of memories, in our patients, treated following a standardized protocol.

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Acute response of neurons: an early event of neuronal cell death after facial nerve injury  Voir?

This study was to research the early acute response events of facial nerve injury.
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Big Data and Clinical Research in Traumatic Brain Injury  Voir?

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Effect of single-level transforaminal lumbar interbody fusion on segmental and overall lumbar lordosis in patients with lumbar degenerative disease  Voir?

This study investigated the ability of transforaminal lumbar interbody fusion (TLIF) to improve lumbar lordosis (LL).
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Lumbar disc arthroplasty for degenerative disc disease: a literature review  Voir?

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Endovascular Treatment of Ruptured Vertebrobasilar Dissecting Aneurysms Using Flow Diversion Embolization Devices: Single-Institution Experience  Voir?

Treatment of ruptured posterior circulation dissecting aneurysms is technically challenging with potentially high morbidity and mortality. We sought to assess the safety and feasibility of using a flow diversion devices (FDD) and a specific acute antiplatelet aggregation protocol in the management of ruptured dissecting aneurysms.

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Intracranial Hemorrhage in Patients with Durable Mechanical Circulatory Support Devices: Institutional Review and Proposed Treatment Algorithm  Voir?

Spontaneous intracranial hemorrhage (ICH) is frequently managed in neurosurgery. Patients with durable mechanical circulatory support devices, including total artificial hearts (TAHs) and left ventricular assist devices (LVADs) are often encountered in the setting of ICH. While durable mechanical circulatory support devices have improved survival and quality of life for patients with advanced heart failure, ICH is one of the most feared complications following LVAD and TAH implantation. Due to anti-coagulation and clinically relevant acquired coagulopathies, ICH should be treated promptly by neurosurgeons and cardiac critical care.

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Pediatric intracranial aneurysms: considerations and recommendations for follow-up imaging  Voir?

Pediatric intracranial aneurysms (IAs) are rare. Compared to adult IAs, they are more commonly giant, fusiform, or dissecting. Their treatment often proves more complex and recurrence rate and de novo aneurysmogenesis incidence is higher. A consensus regarding the most appropriate algorithm for following pediatric IAs is lacking.

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Machine Learning and Neurosurgical Outcome Prediction: A Systematic Review  Voir?

Accurate measurement of surgical outcomes is highly desirable to optimize surgical decision-making. An important element of surgical decision making is identification of the patient cohort that will benefit from surgery prior to the intervention. Machine learning (ML) enables computers to learn from previous data to make accurate predictions on new data. In this systematic review, we evaluate the potential of ML for neurosurgical outcome prediction.

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Microsphere Embolization of Hypervascular Posterior Fossa Tumors: A Technical Note  Voir?

Preoperative embolization of highly vascular tumors of the posterior fossa can decrease morbidity and operative blood loss. No clear consensus exists for the embolization agent of choice for optimal devascularization of these tumors.
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Anterior cervical discectomy with instrumented allograft fusion: Lordosis restoration and comparison of functional outcomes among patients of different age groups  Voir?

To investigate clinical parameters of anterior cervical discectomy and fusion (ACDF) treatment and outcomes using osseous allograft in different age groups, study postoperative results of restoring of lordosis, and evaluate the utility of bone allografts for ACDF, including graft subsidence.
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Internal Carotid Artery and Its Relationship with Structures in Sellar Region: Anatomy Study and Its Clinical Applications  Voir?

Complications of the ICA in surgeries are rare but severe. This study aims to locate the ICA with 5 stationary bony structures in the sellar region: the anterior clinoid process (ACP), the tuberculum sellae, the bottom of the hypophyseal fossa, the posterior edge of the hypophyseal fossa and the post clinoid process and do measurements to determine their anatomic relationship with the ICA.

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Analysis of survival prognosis for children with symptomatic optic pathway gliomas who received surgery  Voir?

The feasibility and prognosis of surgical treatment for children with OPGs is controversial. Therefore, this study attempted to evaluate the effects of surgery and discuss prognostic factors related to the survival of children with symptomatic OPGs.
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Application of gelatin sponge impregnated with a mixture of three drugs to intraoperative nerve root block combined with robot-assisted MIS-TLIF surgery in the treatment of adult degenerative scoliosis: A clinical observation from 96 patients  Voir?

Application of nerve root block mainly for the diagnosis. However, less application in intraoperative treatment.
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Image: Extensive Pneumocephalus  Voir?

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Posterior vertebral column resection through unilateral osteotomy approach for old lumbar fracture combined with Kummell’s disease: A case report  Voir?

Kummell’s disease is a clinical syndrome characterized by a minor spinal trauma with a symptom-free period from months to years, followed by progressive painful kyphosis. There are many surgical options for Kummell’s disease in the previous literature, however, no study mentioning the surgical strategy for patients whose fractured vertebrae was severely compressed and only slice of superior and inferior endplate left.

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Intradural spinal tumors - a review of post-operative outcomes comparing intramedullary and extramedullary tumors from a single institution's experience  Voir?

Intradural spinal tumors are rare and can be classified into extramedullary or intramedullary. They commonly present with symptoms such as intractable back pain or neurological deficits. We retrospectively reviewed 91 cases of intradural spinal tumors that underwent surgery in our institution from 2011 to 2016 and their assessed clinical outcomes. The majority of intradural tumors were extramedullary (89%) and the most common pathology was schwanommas (38.5%) followed by meningiomas (29.7%). Comparing extramedullary vs.

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Alarming Internal Carotid Artery Aneurysm Eroding the Sphenoid Sinus  Voir?

In rare instances, extradural internal carotid artery aneurysms can present with massive epistaxis which is often a fatal event. We present the case of a young female with an aneurysm eroding through the sphenoid sinus and whose timely diagnosis resulted in treatment of the aneurysm with coil embolization and satisfactory outcome.

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Benchmarking Distance Control and Virtual Drilling for Lateral Skull Base Surgery  Voir?

Novel audiovisual feedback methods were developed to improve image guidance during skull base surgery by providing audiovisual warnings when the drill tip enters a protective perimeter set at a distance around anatomical structures (‘distance control’), and visualizing bone drilling (‘virtual drilling’).

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Validation of a Predictive Scoring System for Ventriculoperitoneal Shunt Insertion following Aneurysmal Subarachnoid Hemorrhage  Voir?

Hydrocephalus is a frequently encountered complication in the context of aneurysmal subarachnoid hemorrhage (aSAH). Here, we performed an external validation of the recently proposed Post-Subarachnoid Shunt Scoring (PS3) system, which aims to stratify patients presenting with aSAH based on their relative risk of requiring ventriculoperitoneal (VP) shunt insertion.

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Cerebral aneurysm associated with an arachnoid cyst: three case reports and a systematic review of literature  Voir?

Arachnoid cysts and intracranial aneurysms are not rare, but it is unusual for an aneurysm to be associated with an arachnoid cyst.
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An improved microvascular decompression in treating trigeminal neuralgia: application of nest-shaped Teflon fibers  Voir?

The aim of this study was to develop an improved Microvascular decompression (MVD) surgery using nest-shaped Teflon fibers. Eighteen consecutive trigeminal neuralgia (TN) patients who underwent MVD using nest-shaped Teflon fibers between January 2012 and December 2013 were included in this investigation. During the surgery, the nest shape of Teflon was formed by gently pushing Teflon prosthesis at the center position toward the periphery. Immediate postoperative outcome was evaluated using numerical rating scale (NRS) score, then patients were followed up for recurrence.

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Comparative Study of Cortical Bone Trajectory-Pedicle Screw (Cortical Screw) versus Conventional Pedicle Screw in Single-Level Posterior Lumbar Interbody Fusion: A 2-Year Post Hoc Analysis from Prospectively Randomized Data  Voir?

The aim of this study was to report 2-year follow-up outcomes of posterior lumbar interbody fusion (PLIF) with cortical bone trajectory-pedicle screw (CS), in terms of fusion rates, clinical outcomes, surgical outcomes, and complications, and to compare these outcomes with outcomes for PLIF with conventional pedicle screw (PS).

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Endovascular treatment of unruptured intracranial aneurysms by the woven endobridge device (web): are there any aspects influencing aneurysm occlusion?  Voir?

The experience with Woven Endobridge Device (WEB) is still limited. The aim of this study is to discuss the efficacy of this new device focusing on any anatomical and procedural factors influencing aneurysm occlusion.
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The Long and Winding Road: Thoracic Myelopathy associated with Occipitocervical dAVF  Voir?

Spinal DAVFs have diverse presentations. MRIs reveal spinal cord swelling in only 45-74%. We present an unusual case of a 57 yo male with a craniocervical junction DAVFs in which the edema appeared in the thoracolumbar region skipping the cervical spinal cord.A case report and literature review from a tertiary referral center.In our patient, symptoms progressed over 3 months from low back and radicular pain to weakness, saddle anesthesia, and urinary retention. MRI showed T2 hyperintensity from T3-4 to the conus medullaris (Fig 1 a,b).

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CT-angiography spot sign as an indicator for ultra-early stereotactic aspiration of intracerebral hemorrhage  Voir?

Ultra-early surgical clot removal relieves mechanical compression on adjacent normal brain tissue and limits the toxic effects of a hematoma, which might improve the outcomes in patients with intracerebral hemorrhage (ICH); however, hematoma expansion frequently occurs within 20 h after the ictus, and this limits the use of ultra-early surgery. CT-angiography (CTA) spot sign was recently validated as an important predictor of hematoma expansion in ICH patients.

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Call to Action: A Study to Determine the Etiology of Catastrophic Brain Injuries in High Impact Sporting Activities within the Adolescent Population  Voir?

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Primary Intraosseous Lymphoplasmacyte-Rich Meningioma: A Case Report  Voir?

Lymphoplasmacyte-rich meningioma is an uncommon variant of meningioma, and that arising in the extradural site is extremely rare. Herein, we report a case of primary intraosseous lymphoplasmacyte-rich meningioma. A 51-year-old woman presented with left frontal scalp swelling lasting more than 1 year. Magnetic resonance imaging revealed an intraosseous extradural mass in the left frontal region with bone destruction. Surgical resection of the mass and a cranioplasty was performed. The postoperative course was uneventful, and histopathological findings were consistent with lymphoplasmacyte-rich meningioma.

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Discogenic reactivation of Herpes Zoster  Voir?

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Natalizumab Associated Primary Central Nervous System Lymphoma  Voir?

Natalizumab, a selective adhesion molecule inhibitor binding to α-4 subunit of integrin, has emerged to be an effective immuno-modulator especially in the treatment of relapsing-remitting Multiple Sclerosis and Crohn’s disease. Literature documenting the development of progressive multifocal leukoencephalopathy from its use is widely available. However, only handful of reports cites the development of a more concerning pathology, primary CNS lymphoma (PCNSL) from its administration, thereby triggering a debate on a possible causal association.

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Lymphoblastic lymphoma involving multiple vertebrae  Voir?

Acute lymphoblastic lymphoma (ALL) was a malignant hematological disease in childhood but rarely, initially involved epidural compartment in adult. A 20-year-old male presented with progressive osphyalgia for 2 months and left lower motor weakness for 2 weeks with constipation. Physical examination revealed decreased muscle strength and numbness of left lower limb, and abnormal gait. Contrasted MRI showed multiple vertebrae of hypointense T1 signals (C2/C4/C7/T5/T8/T9/T12/L2/L4) and an intraspinal epidural lesion (L2-4).

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Maggots in the brain: sequelae of ignored scalp wound  Voir?

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A patient with a recurrent anterior cerebral artery dissecting aneurysm after stent-assisted coil embolization successfully treated with A3-A3 anastomosis  Voir?

With recent advances in endovascular devices and techniques, the use of endovascular treatment has been reported for intracranial dissecting aneurysms. However, the efficacy of this endovascular approach for intracranial dissection is still unknown. We report the case of a patient with a recurrent anterior cerebral artery (ACA) dissecting aneurysm after endovascular treatment.

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Intracranial Aneurysms In Adult Moyamoya Disease  Voir?

Reportedly, the prevalence of aneurysm formation in adults with Moyamoya disease (MMD) is approximately 14%, and it represents a major potential hemorrhagic risk. Objectives: We aimed to study the characteristics of intracranial aneurysms occurring in patients with MMD. We retrospectively reviewed our 10-year-experience of patients with intracranial aneurysms who visited our hospital and were diagnosed as having MMD.

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The Effect of July Admission on Inpatient Morbidity, Mortality, and Discharge Disposition after Endovascular Coiling in Subarachnoid Hemorrhage  Voir?

To investigate the effect of July admission on short-term outcome after endovascular coiling of patients with subarachnoid hemorrhage (SAH) due to ruptured aneurysms.
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Transoral Decompression And Stabilization Of The Upper Cervical Segments Of The Spine Using Custom-Made Implants In Various Pathological Conditions Of The Craniovertebral Junction  Voir?

Surgical treatment of patients with atlantoaxial instability caused by pathological changes of the skull base and craniovertebral junction combined with anterior compression of the brain stem is still associated with substantial technical difficulties and remains a matter of debate.Currently, anterior stabilization of the atlantoaxial junction is a promising approach that allows for the resection of the pathological lesion of the skull base and craniovertebral junction with subsequent stabilization of C1-C2 or C1-C3 in one stage.

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Effect of Interlaminar Epidural Steroid Injection in Patients with Central Cervical Spinal Stenosis  Voir?

The authors investigated the effect of interlaminar ESI for the management of central cervical spinal stenosis-induced posterior neck pain.
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Two-Year Results of the Prospective Spine Treatment Outcomes Study: Analysis of Postoperative Clinical Outcomes Between Patients with and without a History of Previous Cervical Spine Surgery  Voir?

History of previous cervical spine surgery is a frequently cited cause of worse outcomes after cervical spine surgery. The purpose of this study was to determine any differences in clinical outcomes after cervical spine surgery between patients with and without a history of previous cervical spine surgery.

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Low Pressure Hydrocephalus: A Case Report and Review of the Literature  Voir?

The entity of low pressure hydrocephalus remains poorly understood and thoroughly debated. Symptomatic improvement accompanied by decrease in ventricular size following prolonged sub-atmospheric drainage has been well documented and this method has been considered the gold standard of management. Few studies have examined alternative treatment options, either to avoid the risks associated with prolonged external ventricular drainage or due to failure of traditional methods.

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Emergency Optic Canal Decompression for Vision Salvage in Fibrous Dysplasia: A Case Report  Voir?

The most common neurological manifestations of fibrous dysplasia (FD) are vision and hearing loss. Optic decompression for progressive vision loss has been shown to yield positive results in terms of visual outcomes, however, emergency optic decompression surgery for sudden loss of vision in FD has not to date been reported in the pediatric population. We report the first case of FD presenting with sudden vision loss and successfully managed with emergency optic decompression.

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Anterior Communicating Artery Aneurysm Morphology and the Risk of Rupture  Voir?

Recently, with improvements in computed tomography angiography (CTA) and digital subtraction angiography (DSA), the assessment of certain morphological traits of anterior communicating artery aneurysms (ACoAAs) has drawn great attention. The determination of specific factors associated with rupture would provide much needed guidance for the treatment of unruptured intracranial aneurysms, such as surgical clipping or endovascular coiling. Morphological factors include, but are not limited to, aneurysm size, number, shape, dome direction, neck-to-dome ratio, and relationship of the aneurysm to the surrounding vessels.

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Evaluating the effectiveness and the impact of donated neurosurgical equipment on neurosurgical units in low and middle income countries: the WFNS experience  Voir?

Surgical practice highly depends on the availability of surgical equipment; this is particularly relevant to low and middle income countries (LMICs), where resources are limited. A key part of the efforts to improve surgical provision globally include providing affordable equipment to LMICs; however, the effectiveness and the impact of these initiatives has not yet been assessed. We aim to evaluate the WFNS neurosurgical equipment program in this context.

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Arachnoid cyst associated chronic subdural hematoma: report of 14 cases and a systematic literature review  Voir?

Arachnoid cyst (AC) associated chronic subdural hematoma (CSDH) differs a lot from its counterparts without AC in epidemiological, demographic, and clinical characteristics, management, and prognosis. To further illustrate the epidemiological, demographic, and clinical characteristics, diagnosis, treatment, and prognosis of AC associated CSDH.

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Recovery of patients with pure diffuse axonal injury who remained in a coma for six hours or more  Voir?

Diffuse axonal injury (DAI) is a traumatic brain injury and one of the most common causes of unfavorable outcome and death. The aim of this study was to investigate the recovery of patients with pure DAI who remained in a coma for 6 hours or more after brain injury.
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Moyamoya disease associated with tuberculum sellae meningioma and cavernous sinus hemangioma: case report  Voir?

Primary moyamoya disease associated with skull base tumors has been rarely reported in the literature. Surgical treatment can be complicated due to the compensatory collateral circulation through meningeal and leptomeningeal anastomosis. The standard frontotemporal craniotomy may interrupt critical transdural anastomoses.

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Microscopic minimally invasive keyhole technique for surgical resection of spinal dumbbell tumors  Voir?

Multiple surgical modalities have been developed and applied for surgical excision of spinal dumbbell tumors. However, the microscopic minimally invasive keyhole technique has not yet been well characterized for this purpose. Here we report our experience with one-stage surgical resection of both intra- and extra-foraminal /paraspinal components of spinal dumbbell tumors using the microsurgical keyhole technique.

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Effectiveness of the 3D monitor system for medical education during neurosurgical operation  Voir?

Three-dimensional (3D) graphics are used in the medical field, especially during surgery. Although 3D monitoring is useful for medical education, its effectiveness needs to be objectively evaluated. The aim of this study was to investigate the efficacy of 3D monitoring in the surgical education of medical students.

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Comparison of Recanalization and In-stent Stenosis between LVIS stent and Enterprise stent-assisted coiling for 254 intracranial aneurysms  Voir?

We compared the rates of recanalization and in-stent stenosis between the Enterprise and Low-profile Visualized Intraluminal Support(LVIS) stent deployments for intracranial aneurysms(IAs), and the factors associated therein.
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Clinical Features, Treatment and Long-term Outcomes of Central Neurocytoma: A 20-Year Experience at a Single Center  Voir?

Central neurocytoma (CN) is a rare central nervous system tumor whose optimal management strategy remains controversial due to their rarity. A thorough research of detail information of CN is very necessary to establish optimal management strategies. The purpose of this study was to demonstrate the clinical features, treatments and long-term clinical outcomes of CN.

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Early transient mild hypothermia attenuates neurological deficits and brain damage after experimental subarachnoid hemorrhage in rats  Voir?

Metabolic exhaustion in ischemic tissue is the basis for a detrimental cascade of cell damage. In the acute stage of subarachnoid hemorrhage (SAH), a sequence of global and focal ischemia occurs, threatening brain tissue to undergo ischemic damage. This study was conducted to investigate whether early therapy with moderate hypothermia can offer neuroprotection after experimental SAH.

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Minimally invasive excision of thoracic arachnoid web  Voir?

Arachnoid webs are rare intradural lesions which can cause direct spinal cord compression and/or alteration of the CSF flow with syringomielia. Surgery has been historically performed via wide open laminectomies. The aim of this study is to prove the feasibility of minimally invasive techniques for the excision of arachnoid webs.

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Stenosis Before Thrombosis – Intracranial Hypertension from Jugular Foramen Stenosis Secondary to Renal Osteodystrophy  Voir?

Venous outflow obstructions are rare anatomic findings that can present with symptoms of elevated intracranial pressure, including headache and vision loss, and can be mistaken for more common diagnoses, such as idiopathic intracranial hypertension (IIH) or cerebral venous sinus thrombosis (CVST). While venous outflow obstructions have been reported in rare bone dysplasias and congenital abnormalities, to date they have not been reported in renal osteodystrophy (ROD), a relatively common disorder seen in patients with chronic kidney disease.

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Diagnosis and Outcomes of 341 patients with Cushing's disease following transsphenoid surgery, a single center experience  Voir?

Transsphenoid surgery (TSS) is a standard treatment modality for Cushing's disease (CD). However, postoperative remission and recurrence rates vary among studies. Here we analyze the diagnosis and outcomes of 341 patients with preoperative diagnosis of CD undergoing TSS in a single center over 3 years.

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Survival Outcomes Prognostication in Glioblastoma Diagnosed Patients  Voir?

Glioblastoma multiforme (GBM) is an aggressive primary brain tumor with most dismal survival rates. This study aims to examine the prognostic value of primary tumor sites and race on survival outcomes.
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Histopathological Features in Relation to Pretreatment Growth in Glioblastoma Patients  Voir?

Rapid growth is a well-known property of glioblastoma (GBM), however, growth rates vary among patients. Mechanisms behind such variation have not been widely studied in human patients. We sought to investigate relationships between histopathological features and tumor growth estimated from pretreatment magnetic resonance imaging (MRI) scans.

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Intraoperative MR imaging and neuronavigation during resection of FCD Type II in adult epilepsy surgery offers better seizure outcome  Voir?

Focal cortical dysplasia (FCD) is one important cause of drug-resistant epilepsy potentially curable by epilepsy surgery. We investigated the options utilizing neuronavigation and intraoperative MR imaging to avoid residual epileptogenic tissue during resection of FCD II patients in order to improve seizure outcome.

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Spinal metastasis of unknown primary accompanied by neurological deficit or vertebral instability  Voir?

Spinal bone metastases are highly common. They are mostly localized to the lumbar, thoracic, and cervical spine, respectively. The most common primaries to result in spinal metastases include lung, breast, and prostate carcinomas in adults as opposed to leukemia, Ewing’s sarcoma, rhabdomyosarcoma, and neuroblastoma in children. In patients diagnosed with a cancer, bone metastases are found in 40% and spinal metastases in 10% of the patients. In this study, we aimed to present 25 patients diagnosed with a spinal metastasis of unknown primary who presented with a low back pain or acute-onset neurological deficits and underwent operative treatment.

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Acute Bilateral Foot Drop as a Presenting Symptom of Hemorrhagic Synovial Cyst of the Lumbar Spine  Voir?

Acute bilateral foot drop is a rare clinical presentation. A 77-year-old male presented with acute bilateral weakness of the foot and ankle dorsiflexion. Magnetic resonance imaging of the lumbar spine revealed ligamentum flavum hypertrophy as well as a mass lesion that appeared hyperintense on T1-weighted images and hypointense on T2-weighted images. Emergent decompressive laminectomy and hemorrhagic synovial cyst excision were performed. Histopathological examination of the tissue revealed a synovial cyst with hemorrhage.

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Occipital intraosseous hemangioma over torcula: unusual presentation with raised intracranial pressure  Voir?

Hemangiomas of the bone are benign, uncommon, slow growing lesions of the bone accounting for less than 1.0% of all bony neoplasms. Intra osseous occipital hemangiomas are very rare and occipital hemangioma presenting with features of raised intracranial tension is still rare, till now only 2 of such cases are reported.

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Effects of different therapeutic approaches on the diagnosis of glioblastoma and detection of its recurrence  Voir?

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Revision Rate of Misplaced Pedicle Screws of the Thoracolumbar Spine - Comparison of 3D Fluoroscopy Navigated with Freehand Placement - A Systematic Analysis and Review of the Literature  Voir?

Recent studies could show higher accuracy rates of image-guided pedicle screw placement compared to freehand placement. However, data focusing on the impact of spinal navigation on the rate of revision surgeries due to misplaced pedicle screws (PS) are scarce.
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Clinical Accuracy of Customized Stereotactic Fixtures for Stereo-EEG  Voir?

Stereo-EEG is a diagnostic methodology involving 3D exploration of brain structures using depth electrodes for locating epileptogenic foci in patients with drug-resistant epilepsy. A variety of frame-based, frameless, and robotic stereotactic systems have been designed for the accurate placement of depth electrodes.

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Surgical Treatment of Mirror MCA Aneurysms: Bilateral and Unilateral Approach  Voir?

Currently, the optimal surgical approach for bilateral aneurysms remains controversial. Alternative interventional methods, such as unilateral or bilateral approaches, have been employed during a single session or two different sessions. The unilateral approach can be employed successfully to treat contralateral aneurysms that develop in a paramedian location. However, such an approach is more difficult for treating contralateral aneurysms in more distant locations. Unilateral approach can decrease complication rates, operation time and the length of hospital stay.

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Schwannomas of the Frontal Sinus: Cases and Review of the Literature  Voir?

Although schwannomas are commonly found in the head and neck region, their presence in the sinonasal tract involvement is extremely rare, estimated as less than 4%. The presence of these lesions in the frontal sinus are even less common. We report two patients with schwannomas originating in the frontal sinus, with variable degrees of extension. These patients underwent resection of the tumors via an endoscopic or combined approach. The histological diagnosis confirmed schwannoma. Though these lesions have traditionally been approached through larger craniotomies and open procedures, these cases represent less invasive approaches for these rare frontal sinus schwannomas, and demonstrate them as a valid alternative with minimal morbidity for the patient.

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Giant Cell Ependymoma of the Lateral Ventricle: Case Report, Literature Review, and Analysis of Prognostic Factors and Genetic Profile  Voir?

Giant cell ependymoma (GCE) is a rare primary CNS neoplasm. We report a case of GCE arising in the lateral ventricle. A 22-year-old female presented with generalized seizures. MRI demonstrated a diffuse, non-enhancing, multi-cystic mass centered in the atrium of the right lateral ventricle with extension throughout the frontal and temporal horns. An initial subtotal resection yielded the signature biphasic pattern of GCE. The dominant component contained pleomorphic, bizarre-appearing giant cells with low mitotic index, and a minor component comprised monomorphic, highly cellular, mitotically active cells that formed perivascular pseudorosettes.

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Occipital microAVM Resection, Strategy and Nuances  Voir?

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Rotational Vertebral Artery Dissection Secondary to an Anomalous Entrance into Transverse Foramen: Case Report  Voir?

Rotational vertebral artery occlusion is a rare syndrome characterized by vertebrobasilar insufficiency secondary to position-dependent occlusion of the vertebral artery. Most cases reported in the literature have been attributed to osteophytic compression, either from the occipital condyle or within the transverse foramen. However, vertebral artery dissection secondary to motion in the setting of anomalous anatomy has not been reported.

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The availability of a tin-alloyed omnidirectional retractor-supporting ring for ventriculoperitoneal shunt laparotomy: technical note  Voir?

We report the availability of a newly developed, malleable, tin-alloyed omnidirectional retractor-supporting (OD) ring for steady and safe ventriculoperitoneal (VP) shunt laparotomy.
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Top 100 most-cited articles on Spontaneous Intracerebral Hemorrhage: A bibliometric analysis  Voir?

A bibliometric uses the citation count of an article to determine its impact on the clinical world. There is a paucity of literature concerning top article citations on spontaneous intracerebral hemorrhage (ICH). The main objective of this investigation was to bridge this gap and to provide understanding of the trends on the most influential articles written on this subject.

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Severe cerebral complications secondary to perforation injury of the anterior skull base during sinonasal surgery: an underappreciated problem?  Voir?

Functional endonasal sinus surgery (FESS) is widely practiced and is considered a generally safe procedure. Skull base injuries occur in less than 1% of procedures and are typically associated with cerebrospinal fluid leaks. Rarely, skull base injuries might result in cerebral lesions. Here we present a series of four patients with iatrogenic perforating injuries of the anterior skull base and cerebral lesions after routine FESS.

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First Report of Renal Cell Carcinoma Metastasizing to the Clivus in a Pediatric Patient  Voir?

The clivus is a rare site of tumor occurrence in general, and metastases to this site are especially rare. Renal cell carcinoma is an uncommon entity in the pediatric population. Although not infrequent in adults, when it does occur, metastases to the clivus are extremely uncommon, only having been reported 3 times in the literature. All of these cases involved adults in their sixth decade.

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Integration of fMRI and MEG functional maps into a CyberKnife planning system: feasibility study for motor activity localization and dose planning  Voir?

Magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) provide non-invasive localization of eloquent brain areas for pre-surgical planning. The aim of this study is the integration of MEG and fMRI maps into a CyberKnife (CK) system to optimize dose planning.
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Ganglioglioma Progression to Combined Anaplastic Ganglioglioma and Anaplastic Pleomorphic Xanthoastrocytoma. Case Report and Literature Review  Voir?

Composite ganglioma and pleomorphic xanthoastrocytoma with anaplastic features in both components is an extremely rare glioneuronal tumor. Five cases of anaplastic progression in the glioma component have been reported. These tumors generally affect young patients who have brain tumor-related epilepsy, which are usually located in the temporal lobe or in the cerebellum and may have associated leptomeningeal spreading. Its current optimal treatment consists of maximal safe surgical resection and adjuvant chemoradiotherapy.

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Lumbar Spine Infection by Granulicatella and Abiotrophia Species  Voir?

The Granulicatella and Abiotrophia species are streptococci and natural inhabitants of the oral and urogenital flora. They are uncommonly associated with human pathology, although they can cause septicemia, endocarditis, or bacteremia. These microorganisms are difficult to culture and identify due to particular microenvironment requirements. Rarely, presentation is osteomyelitis or infections of the spine.

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Minimally Invasive Separation Surgery with Intraoperative Stereotactic Guidance: A Feasibility Study  Voir?

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Long-Term Patency of Posterior Auricular Artery—Middle Cerebral Artery Bypass for Adult-Onset Moyamoya Disease: Case Report and Review of Literature  Voir?

Direct extracranial-intracranial (EC-IC) bypass is one of the fundamental techniques to prevent recurrent stroke in patients with adult-onset ischemic moyamoya disease. When the standard superficial temporal artery (STA) cannot be used for a graft, the posterior auricular artery (PAA) can be a potential surrogate graft.

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Chronic Subdural Hematoma: a Historical and Clinical Perspective  Voir?

Chronic subdural hematoma (cSDH) affects 1-5.3 per 100,000 individuals annually, with the incidence expected to rise as the U.S. population ages. The symptoms of cSDH are often nonspecific, with headaches being the most common complaint. Other symptoms include weakness, balance and gait problems, and memory problems. A variety of clinical factors must be taken into account in the treatment of cSDH, and the multifaceted treatment paradigms continue to evolve. This review aims to highlight the clinical complexity of cSDH, while presenting a brief historical discussion of cSDH.

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Chronic Subdural Hematoma: a Perspective on Subdural Membranes and Dementia  Voir?

Chronic subdural hematoma (cSDH) is a common intracranial pathology, and a leading cause of reversible dementia. cSDH is projected to affect at least 60,000 new individuals in the United States annually by 2030.This can result from mild to moderate head trauma that leads to hemorrhaging in the dura-arachnoid interface. The short and long-term effects of cSDH and the subdural membrane on the pathogenesis of dementia and the newly discovered dural lymphatics is a topic of increasing importance. This manuscript aims to review the complex pathogenesis of the subdural membrane, and the link between head trauma, dementia, and dural lymphatics.

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Results of combined intraventricular neuroendoscopic procedures in 130 cases with special focus on fornix contusions  Voir?

The growing experience with intraventricular neuroendoscopic procedures showed good results in the combination of ETV and tumor biopsy. Other possible combinations are mainly presented in subgroups in the literature. Here, the authors present their experience with combined intraventricular procedures within one setting over the last two decades.

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Photoacoustic Imaging for Maximizing Glioma Resection  Voir?

Increased extent of resection for both low- and high-grade gliomas has been shown to improve progression-free and overall survival. An extent of resection >98% or a contrast-enhancing residual tumor volume of <2 cm3 has been shown to significantly increase survival for patients with glioblastoma multiforme.1 Similarly, residual tumor volume of <15 cm3 improves survival for patients with low-grade gliomas.2 Current modalities used to maximize resection are 5-aminolevulinic acid (5-ALA) fluorescence and intraoperative magnetic resonance imaging (MRI).

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Reading Between the Joints—Using Spinal Magnetic Resonance Imaging for Evaluation of Instability  Voir?

Magnetic resonance imaging (MRI) is one of the most common investigations ordered for the evaluation of back and leg pain. Usually, supine MRI is one of the initial tests for the screening of degenerative spine diseases and lumbar spinal stenosis. It is useful for assessing disease severity, involvement of the spine and its surrounding structures, and making decisions about surgery. With all of these advantages in hand, the role of MRI is considered limited in a few aspects—one is the determination of instability.

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Treatment of Large or Giant Cavernous Aneurysm Associated with Persistent Trigeminal Artery: Case Report and Review of Literature  Voir?

Primitive trigeminal artery (PTA) is the most common anomaly of primitive carotid-basilar anastomosis and is associated with cerebrovascular anomalies, such as aneurysm. Large or giant cavernous aneurysm associated with PTA is rare, and the treatment strategies differ in comparison with large or giant aneurysm without PTA. In this article, we report an unusual case of a giant cavernous aneurysm associated with PTA and review treatment strategies for large or giant cavernous aneurysm associated with PTA.

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Spontaneous Hemorrhagic Glioblastoma Revealed by Arterial Spin Labeling  Voir?

We report a case of hemorrhagic tumor detected early by pseudocontinuous arterial spin labeling sequence when conventional magnetic resonance imaging sequences were not contributive.
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Robotic Stereotactic Assistance (ROSA) utilization for minimally invasive placement of intraparenchymal hematoma and intraventricular catheters: Case report  Voir?

In patients with supratentorial spontaneous intracerebral hemorrhage, intrahematomal catheter placement may allow for intra-clot thrombolysis and drainage. Robotic assistance may be used for the stereotactic placement of catheters.
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Spine Surgery: Tricks of the Trade, Third Edition  Voir?

Spine Surgery: Tricks of the Trade, Third Edition, by Drs. Alexander R. Vaccaro and Todd J. Albert, offers an outstanding update to their already-essential spine surgery reference manual. At more than 400 pages, the content in this book has been significantly expanded from the previous edition. Surgeons in need of a quick, yet thorough, review of key procedures in the field of spine surgery will find that this reference delivers. The field of spine surgery is broad, dynamic, and constantly evolving with new technology and procedures, and to summarize all of the relevant traditional and newer techniques in a concise yet complete manner is a monumental task.

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Craniospinal Germinomas in Patient with Down Syndrome Successfully Treated with Standard-Dose Chemotherapy and Craniospinal Irradiation: Case Report and Literature Review  Voir?

Patients with Down syndrome (DS) are more likely to develop chemotherapy-related complications. The standard treatment for these patients with cancer has not yet been established, and the risks of standard chemotherapy are unclear. In this paper, a rare case of multiple craniospinal germinomas in a patient with DS, which was successfully treated with standard-dose chemotherapy combined with craniospinal irradiation, is reported.

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A Tortuous Process of Surgical Treatment for a Large Calcified Chronic Subdural Hematoma  Voir?

Calcified chronic subdural hematoma (CCSDH) is a rare disease for which no standard approach to treatment has been established. Reports covering both burr hole trepanation and craniotomy for CCSDH are rare. Furthermore, infection of CCSDH after the burr hole trepanation has not been reported in the literature.

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Morbidity and Mortality of Meningioma Resection Increases in Octogenarians  Voir?

The incidence of meningioma has increased drastically recently, particularly in the elderly. Surgical intervention has the potential to reduce neurological symptoms and to achieve favorable, long-term outcomes. There is considerable variability in the literature examining the relationship between age and outcomes following meningioma surgery. The objective of this study was to identify the relationship between age and postoperative complications following craniotomy for resection of meningioma.

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Stereoscopic Three-Dimensional Neuroanatomy Lectures Enhance Neurosurgical Training: Prospective Comparison with Traditional Teaching  Voir?

Stereoscopic three-dimensional (3D) imaging is increasingly used in the teaching of neuroanatomy and although this is mainly aimed at undergraduate medical students, it has enormous potential for enhancing the training of neurosurgeons. This study aims to assess whether 3D lecturing is an effective method of enhancing the knowledge and confidence of neurosurgeons and how it compares with traditional two-dimensional (2D) lecturing and cadaveric training.

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Early outcomes of endoscopic contralateral foraminal and lateral recess decompression via an interlaminar approach in patients with unilateral radiculopathy from unilateral foraminal stenosis  Voir?

Percutaneous endoscopic contralateral interlaminar lumbar foraminotomy (PECILF) for lumbar degenerative spinal stenosis is an established procedure. Better preservation of contralateral facet joint compared to that of the approach side has been demonstrated with uniportal bilateral decompression. The aim of this retrospective case series was to analyze the early clinical and radiological outcomes of standalone contralateral foraminotomy and lateral recess decompression using PECILF.

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Successful treatment by microvascular decompression surgery of a patient with hemiparesis due to vertebral artery compression of the medulla oblongata: A case report and literature review  Voir?

Little literature is available on hemiparesis caused by vascular medullary compression, which may occur as a result of dolichoectasia of the vertebrobasilar arterial system. In this paper, we report a case of vertebral artery compression of the medulla oblongata in a 67-year old woman. The patient was hypertensive and developed hemiparesis and intermittent spasms for five years, which became worsened for one year. Cranial nerve MRI showed compression of the medulla oblongata by the left vertebral artery.

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Acquired Chiari I Malformation with Syringomyelia Secondary to Colloid Cyst with Hydrocephalus—Case Report and Review of Literature  Voir?

Acquired Chiari malformation and associated syringomyelia have been previously described following lumbar puncture/drainage, lumboperitoneal shunts, and spontaneous cerebrospinal fluid leakage. In addition to these etiologies, space-occupying lesions such as meningiomas, epidermoid cysts, medulloblastomas, and arachnoid cysts are rare causes of acquired Chiari malformation and syringomyelia. We report a rare case of colloid cyst with hydrocephalus causing secondary Chiari malformation with syringomyelia.

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A Pilot Study of the Level of Evidence and Collaboration in Published Neurosurgical Research  Voir?

Large-scale studies analyzing neurosurgical published research are lacking.
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Medullary Decompression by Sling Repositioning of Vertebral Artery with Operative Video  Voir?

Vascular compression of the medullary pyramid resulting in neurologic compromise is rare; therefore diagnosis is difficult and ultimately delayed. Most patients present with a combination of cranial nerve, autonomic, and/or motor and sensory dysfunction. Presentation with a single sign such as hemiparesis is rare. The low number of cases reported has made it impossible to define a standard treatment for this unusual disorder.

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Altered Expression of MicroRNA-15a and Kruppel-Like Factor 4 in Cerebrospinal Fluid and Plasma After Aneurysmal Subarachnoid Hemorrhage  Voir?

Cerebral vasospasm (CVS) is a major determinant of prognosis in patients with subarachnoid hemorrhage (SAH). Alteration in the vascular phenotype contributes to development of CVS. However, little is known about the role of microRNAs (miRNAs) in the phenotypic alteration after SAH. We investigated the expression profile of miRNAs and the chronologic changes in the expression of microRNA-15a (miR-15a) and Kruppel-like factor 4 (KLF4), a potent regulator of vascular phenotype modulation that modulates the expression of miR-15a, in the plasma and cerebrospinal fluid (CSF) of patients with SAH.

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Cervical En-Plaque Extradural Meningioma Involving Brachial Plexus  Voir?

Meningioma is one of the commonest spinal tumors, with a predilection for intradural occurrence. Its occurrence as an extradural, en plaque variety with extension into the brachial plexus is unusual.
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Minimally Invasive Treatment for a Sacral Tarlov Cyst Through Tubular Retractors  Voir?

Tarlov cysts (TC) are focal dilations of arachnoid and dura mater of the spinal posterior nerve root sheath that appear as cystic lesions of the nerve roots typically in the lower spine, especially in the sacrum, which can cause radicular symptoms when they increase in size and compress the nerve roots. Different open procedures have been described to treat TCs, but no minimally invasive procedures have been described to effectively address this pathology.

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Lumbosacral Subdural Hematoma After Glioblastoma Multiforme Resection: Possible Radiographic Evidence for the Downward Migration of Intracranial Blood  Voir?

Spinal subdural hematomas (SSDHs) are rare and usually associated with bleeding diatheses, trauma, iatrogenic injury, spinal vascular malformations, or intraspinal tumors.
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Marginal en bloc resection of C2-3 chordoma with bilateral vertebral artery preservation and mesh cage reconstruction with review of previously published cases  Voir?

Chordomas arise from remnants of the notocord and occur throughout the neuroaxis. En bloc resection of chordomas can prove especially challenging in the upper cervical spine secondary to the unique structural anatomy and intimate relationship to the vertebral arteries and spinal cord.
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Cerebrospinal Fluid Leak Rhinorrhea after Systemic Erlotinib Chemotherapy for Metastatic Lung Cancer: A Familiar Problem from an Unfamiliar Culprit  Voir?

Cerebrospinal fluid (CSF) rhinorrhea after medical therapy for pituitary prolactinoma is a rare but well-described phenomenon. To our knowledge, no CSF leaks have been reported after targeted medical treatment of pituitary or anterior skull base metastases. We report this unusual case to raise awareness of spontaneous CSF leaks in the setting of skull base metastatic disease.

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Comparison of unilateral and bilateral craniotomy for the treatment of bilateral middle cerebral artery aneurysms: anatomical and clinical parameters and surgical outcomes  Voir?

To compare two craniotomy approaches (unilateral and bilateral) in terms of anatomical and clinical parameters and surgical outcomes.
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Corrigendum to ‘Jack Nicholson: A Reel and Real-Life Contribution to Neurosciences’ [World Neurosurgery 101 (2017) 718–721]  Voir?

The authors regret that the following Acknowledgement text was missing from the original published article: “We sincerely thank Dr. Kulbir Singh Walia (MD) from New Jersey for his valuable inputs. We also thank Miss Shtantika Mukherjee for language edits and Dr. Prashant K Prasad for his valuable inputs.”

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Short-Term Outcome Comparison Between Full-Endoscopic Interlaminar Approach and Open Minimally Invasive Microsurgical Technique for Treatment of Lumbar Disc Herniation  Voir?

To compare postoperative pain control and functional outcome between full-endoscopic interlaminar approach (FEIA) and open minimally invasive microsurgical technique (MMST) for lumbar discectomy.
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Joint Capsule–Like Intracranial Osteochondroma Mimicking Cystic Meningioma  Voir?

This report provides the first representative images of an intracranial osteochondroma with a cystic component mimicking cystic meningioma. A 40-year-old male presented at our outpatient clinic with decreased sensation in his right upper extremity. Preoperative computed tomography showed a tumor with a cystic meningioma–like appearance and prominent calcifications. On magnetic resonance imaging, calcification of the lesion was suggested by the T2-weighted image; weak enhancement was seen on the T1-weighted image.

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A systematic review of radiosurgery versus surgery for neurofibromatosis type 2 vestibular schwannomas  Voir?

Neurofibromatosis type 2 (NF2) is an autosomal dominant disease characterized by bilateral vestibular schwannomas (VS). NF2-associated VS (NF2-VS) are routinely treated with microsurgery; however, stereotactic radiosurgery (SRS) has emerged as an effective alternative in recent decades. To better elucidate the role of SRS in NF2-VS, a systematic review of the literature was conducted to compare outcomes of SRS versus surgery.

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Remote Thoracic Myelopathy From a Spinal Dural Arteriovenous Fistula at the Craniocervical Junction: Case Report and Review of Literature  Voir?

The craniocervical junction is a rare location for spinal dural arteriovenous fistulas (dAVFs). Typically, fistulas at this location present with findings related to intracranial cortical venous reflux or cervical myelopathy. We present a case of craniocervical junction dAVF with isolated clinical and radiographic findings of thoracolumbar myelopathy.

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Nontraumatic Multiple Vertebral Compression Fractures Induced by Primary Hyperparathyroidism: A Case Report and Literature Review  Voir?

Primary hyperparathyroidism (PHPT) is one of the causes of osteoporosis and is known to increase the fracture risk of bone. However, multiple vertebral compression fracture because of PHPT is extremely rare.
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Models of Mortality and Morbidity in Severe Traumatic Brain Injury: An Analysis of a Singapore Neurotrauma Database  Voir?

Current prognostic models for traumatic brain injury (TBI) are developed from diverse historical data sets. We aimed to construct a prognostication tool for patients with severe TBI, as this group would benefit most from an accurate model.
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Decompressive Cranioplasty in a Patient with Osteopetrosis  Voir?

Osteopetrosis is a heterogeneous group of uncommon congenital disorders that causes bony sclerosis and remodeling. Patients who are symptomatic can show significant neurologic consequences with the involvement of cranial nerves and symptoms of increased intracranial pressure (ICP).
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Extensive Mirror-Image Neurofibromas of Entire Spine Resulting in Spastic Tetraplegia  Voir?

Neurofibromatosis 1 (NF1) is associated with increased incidence of spinal tumors including neurofibromas. The majority of NF1-associated spine neurofibromas are asymptomatic; however, a minority of patients will experience neurologic symptoms that can range from mild paresthesia, radiculopathy, myelopathy, and focal weakness to quadriplegia in extreme cases.We present a 21-year-old male diagnosed with NF1 in infancy and followed for multiple mirror-image neurofibromas involving the entire spine.

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Regression of Recurrent High-Grade Glioma with Temozolomide, Dexamethasone, and Levetiracetam: Case Report and Review of the Literature  Voir?

Treatment options for recurrent glioma of the brain include chemotherapy, radiotherapy, surgery, and palliation. Temozolomide appears to be effective in patients with recurrent high-grade gliomas.
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Recurrent Bleeding After Perimesencephalic Hemorrhage  Voir?

Perimesencephalic hemorrhage (PMH) is a type of subarachnoid hemorrhage with excellent long-term outcomes. Only 1 well-documented case of in-hospital rebleeding after PMH is described in the literature, which occurred after initiating antithrombotic treatment because of myocardial ischemia. We describe a patient with PMH without antithrombotic treatment who had 2 episodes of recurrent bleeding on the day of ictus. To validate the radiologic findings, we conducted a case-control study. Six neuroradiologists and 2 neuroradiology fellows performed a blinded assessment of serial unenhanced head computed tomography (CT) scans of 8 patients with a perimesencephalic bleeding pattern (1 index patient, 6 patients with PMH, 1 patient with perimesencephalic bleeding pattern and basilar artery aneurysm) to investigate a potential increase in amount of subarachnoid blood.

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Is There a Place for the Posterior Approach in Cases of Acute Myelopathy on Thoracic Disc Hernia?  Voir?

Acute myelopathy in cases of thoracic disc herniation (TDH) is an exceptional condition for which the treatment is not codified. Here we present the results of a standardized procedure in 10 patients who underwent surgery for acute myelopathy on TDH between December 2009 and December 2016.
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Surgical “Fat Patch” Improves Secondary Intracranial Hypotension Orthostatic Headache Associated with Lumbosacral Dural Ectasia  Voir?

Secondary intracranial hypotension is a clinical syndrome associated with reduction of cerebrospinal fluid volume and dural continuity violation. The main symptoms are orthostatic headache associated with nausea, vomiting, diplopia, dizziness, and tinnitus. The treatment is usually nonspecific.
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Staged Trapping of Traumatic Basilar Trunk Pseudoaneurysm: Case Report and Review of Literature  Voir?

Traumatic intracranial aneurysms (TICAs) of the posterior circulation in the pediatric populations are rare. Only a few reports in the literature document basilar artery TICA in the pediatric population. These cases were typically associated with a clival fracture and commonly diagnosed weeks to months after trauma. We present a case of a patient with a basilar TICA diagnosed after a motor vehicle collision treated with staged trapping and review of the literature.

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Spinal Cord Astrocytoma with Isocitrate Dehydrogenase 1 Gene Mutation  Voir?

In 2016, the World Health Organization updated its classification of tumors, adding genetic profiles to the conventional histopathologic typing.
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Revascularization Operation for Moyamoya Disease with Concurrent von Willebrand Disease  Voir?

Although extracranial-intracranial (EC-IC) bypass is an effective treatment strategy for symptomatic moyamoya disease, surgeons need to be cautious regarding the possibility of postoperative hemorrhagic complications in patients with a concurrent coagulation disorder. Here, we describe a case of EC-IC bypass for moyamoya disease concurrent with von Willebrand disease type 1.

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Intradural Chordoma of Cerebellopontine Angle: Case Report and Review  Voir?

Chordomas are rare, notochord-derived neoplasms. Of these tumors, intradural chordomas are exceedingly rare. Most occur within the prepontine, parasellar, or other midline intradural locations. An intradural chordoma arising from the cerebellopontine angle has not been described previously.
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Presurgical Administration of mTOR Inhibitors in Patients with Large Subependymal Giant Cell Astrocytoma Associated with Tuberous Sclerosis Complex  Voir?

Direct surgical resection remains the standard treatment for patients with tuberous sclerosis complex (TSC) with a large subependymal giant cell astrocytoma (SEGA). Rapamycin or everolimus is seldom used in these patients because of the risk of increased intracranial pressure and possibility of sudden death.

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Treating Cerebrospinal Fluid Rhinorrhea without Dura Repair: A Case Report of Posterior Fossa Choroid Plexus Papilloma and Review of the Literature  Voir?

Choroid plexus papilloma revealed by nontraumatic cerebrospinal fluid (CSF) rhinorrhea has only been described 5 times, to our knowledge, in the literature. The challenges in this situation are to recognize CSF leak, to rapidly understand the pathophysiology of the leak, and to choose the best treatment strategy in emergency. We report an original case of posterior fossa choroid plexus papilloma revealed by CSF leak. We then discuss the surgical strategy and the pathophysiology of CSF leak, which is explained, in this case, by both hyperproduction of CSF and local skull base erosion.

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Effects of Transcranial Direct-Current Stimulation on Neurosurgical Skill Acquisition: A Randomized Controlled Trial  Voir?

Recent changes in surgical training environments may have limited opportunities for trainees to gain proficiency in skill. Complex skills such as neurosurgery require extended periods of training. Methods to enhance surgical training are required to overcome duty-hour restrictions, to ensure the acquisition of skill proficiency. Transcranial direct-current stimulation (tDCS) can enhance motor skill learning, but is untested in surgical procedural training. We aimed to determine the effects of tDCS on simulation-based neurosurgical skill acquisition.

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Mechanisms, Treatment, and Patient Outcome of Iatrogenic Injury to the Brachial Plexus–A Retrospective Single-Center Study  Voir?

Injury to the brachial plexus is a devastating condition, with severe impairment of upper extremity function resulting in distinct disability. There are no systematic reports on epidemiology, causative mechanisms, treatment strategies. or outcomes of iatrogenic brachial plexus injury (iBPI).
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Prognostic Impact of Health Care–Associated Meningitis in Adults with Intracranial Hemorrhage  Voir?

Health care–associated meningitis and ventriculitis (HCAMV) occurs in adults with intracranial hemorrhage (ICH) and is associated with high rates of morbidity and mortality, but the prognostic impact of this infectious complication in a controlled matched study of ICH is unknown.
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Surgical Treatment of Cavernous Malformations Involving the Midbrain: A Single-Center Case Series of 34 Patients  Voir?

Cavernous malformations (CMs) involving the midbrain are more challenging for surgical treatment than are CMs at other sites because of the surrounding critical structures and deep location. However, specific features and treatment strategies have not been well illustrated.
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Multilevel Posterior Column Osteotomies Are Not Inferior For the Correction of Rigid Adult Spinal Deformity Compared with Pedicle Subtraction Osteotomy  Voir?

Posterior column osteotomy (PCO) has been used for the correction of various spinal deformities. However, little evidence is available regarding the effects of multilevel PCO in adult spinal deformity (ASD) surgery. This study aimed to show the usefulness of PCO in rigid ASD surgery by assessing radiographic and clinical outcomes. We also aimed to assess the corrective potential of multilevel PCOs compared with a single-level pedicle subtraction osteotomy (PSO).

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Posttraumatic Uncal Herniation in a Conscious Patient  Voir?

The incidence of primary traumatic oculomotor nerve palsies in craniocerebral trauma is approximately 1.2% and is usually persistent and associated with loss of consciousness, other neurologic deficits, and skull base or orbital fractures. This case is a rare demonstration of complete left third nerve palsy from uncal herniation after trauma without any loss of consciousness.

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Delayed Catheter-Related Intracranial Hemorrhage After a Ventriculoperitoneal or Ventriculoatrial Shunt in Hydrocephalus  Voir?

Delayed catheter-related intracranial hemorrhage is not rare after a ventriculoperitoneal (VP) or ventriculoatrial (VA) shunt for the treatment of hydrocephalus. Immediate postoperative catheter-related intracranial hemorrhage is possibly due to the procedure itself; however, delayed intracranial hemorrhage may have other underlying mechanisms. This study aimed to investigate the clinical characteristics and reveal the risk factors of delayed catheter-related intracranial hemorrhage after a VP or VA shunt.

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Hybrid Bone SPECT/CT Imaging in Evaluation of Chronic Low Back Pain: Correlation with Facet Joint Arthropathy  Voir?

Evidence to support the use of bone hydroxydiphosphonate (HDP) single photon emission computed tomography (SPECT/CT) in patients with facetogenic low back pain (LBP) is still limited. In this study we compared the scintigraphic patterns on bone SPECT/CT with the degree of structural facet joint (FJ) degeneration on CT in patients with LBP.

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Comparison of the Total and Hidden Blood Loss in Patients Undergoing Open and Minimally Invasive Transforaminal Lumbar Interbody Fusion  Voir?

This study examined the volume of hidden blood loss (HBL) and compared perioperative blood loss between minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and open transforaminal lumbar interbody fusion (O-TLIF).
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It Is Time to Reduce Free-Hand Manipulation: Case Report of Our Proposal for an Innovative 1-Step Cranioplasty  Voir?

Cranioplasty is a well-known procedure, and autologous graft bone is usually considered the best choice in this procedure, but it cannot be used in conditions such as bone-infiltrating tumors, spheno-orbital en plaque meningiomas, and bone infections. Polymethylmethacrylate (PMMA) offers great possibility of intraoperative adaption. We describe a case of 1-step cranioplasty performed in a patient with a meningeal fibrosarcoma using a custom-made silicon mold.

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Risk Factors of Postoperative Low Back Pain for Low-Grade Degenerative Spondylolisthesis: An At Least 2-Year Follow-Up Retrospective Study  Voir?

A retrospective study was conducted to clarify the risk factors of postoperative low back pain (LBP) for low-grade degenerative spondylolisthesis.
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Endovascular Mechanical Thrombectomy for Acute Middle Cerebral Artery M2 Segment Occlusion: A Systematic Review  Voir?

The benefit of endovascular mechanical thrombectomy (EMT) for acute distal occlusions of the middle cerebral artery M2 segment is incompletely defined. The aim of this systematic review is to analyze the recent literature regarding EMT for acute M2 occlusions.
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Regression of Pineal Lesions: Spontaneous or Iatrogenic? A Case Report and Systematic Literature Review  Voir?

Tumors arising from the pineal region account for approximately 1% of intracranial neoplasms. We present a case of a previously healthy 5-year-old boy with an acute onset of headache. A magnetic resonance imaging (MRI) scan showed a pineal mass with aqueduct compression. The patient was scheduled for tumor resection. An endoscopic third ventriculostomy was performed in advance for the treatment of hydrocephalus. Afterwards, MRI showed a relevant regression of the pineal mass without specific treatment.

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Relationship Between Clot Quality and Microguidewire Configuration During Endovascular Thrombectomy for Acute Ischemic Stroke  Voir?

Although endovascular approaches for acute ischemic stroke have been developed, the appropriate selection and sequence of device application or other treatments is unclear. If information about the clot quality can be obtained before the selection of devices, fast recanalization with a suitable device and strategy can be achieved. We studied the relationship between clot quality and the configuration of a microguidewire during endovascular thrombectomy.

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Skull Metastasis from the Liver: Case Report and Literature Review  Voir?

Calvarial metastasis from liver cirrhosis in the absence of a primary focus is exceptionally rare. Few reports of metastases from hepatocellular carcinoma of an unknown primary focus have been published.
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Guidewire Breakage During Cavernous Sinus Sampling: A Rare Complication and Its Treatment  Voir?

Venous sampling methods are valuable tools for the diagnosis of pituitary adenomas. However, these interventions also have complications, which may complicate the treatment process.
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Clinical Investigation of Refractory Chronic Subdural Hematoma: A Comparison of Clinical Factors Between Single and Repeated Recurrences  Voir?

Chronic subdural hematoma (CSDH) is sometimes refractory, and this is troublesome for neurosurgeons. Although many studies have reported risk factors or treatments in efforts to prevent recurrence, those have focused on single recurrence, and few cumulative data are available to analyze refractory CSDH.

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Analysis of Predictors and Probability of Aneurysm Occlusion in the Internal Carotid Artery After Treatment with Pipeline Embolization Device  Voir?

Although the Pipeline Embolization Device (PED) has proved to be an excellent option for internal carotid artery (ICA) aneurysms, the rate of occlusion remains difficult to predict and factors associated with aneurysm occlusion are not well elucidated. This study aimed to investigate predictors and the rate of occlusion for aneurysms along the ICA.

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Relevance of Postoperative Magnetic Resonance Images in Evaluating Epidural Hematoma After Thoracic Fixation Surgery  Voir?

It is difficult to evaluate the significant findings of epidural hematoma in magnetic resonance images (MRIs) obtained immediately after thoracic posterior screw fixation (PSF).
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Long-Term Outcomes of Surgical Treatment in 181 Patients with Supratentorial Cerebral Cavernous Malformation–Associated Epilepsy  Voir?

To evaluate the efficacy of surgery as a treatment for supratentorial cerebral cavernous malformation–associated epilepsy (SCCMAE) and determine the factors that influence outcomes.
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An Unusual Combination of Mirror-Image Dextrocardia with Familial Medulloblastoma: Is There a Histogenetic Relationship?  Voir?

The occurrence of medulloblastoma in the absence of hereditary syndromes is rare. Dextrocardia with situs inversus is also called mirror-image dextrocardia. A combination of mirror-image dextrocardia with medulloblastoma has not been reported previously. To the best of our knowledge, this is the first report of this rare combination in a family with medulloblastoma.

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A Retrospective Study of Thoracolumbar Fractures Treated with Fixation and Non-fusion Surgery of Intra-vertebral Bone Graft Assisted with Balloon Kyphoplasty  Voir?

Posterior fixation and fusion is the primary treatment for thoracolumbar fractures, although this treatment may sacrifice range of motion (ROM) to achieve stability, rather than treating the fracture itself. Two issues addressed when treating thoracolumbar fractures include 1) replacing the fractured vertebrae, especially the upper endplate of the injured vertebrae, and 2) providing strong fixation with biomechanical stability and flexibility.

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Multimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma  Voir?

Structural magnetic resonance imaging (MRI) and histopathologic tissue sampling are routinely performed as part of the diagnostic workup for patients with glioma. Because of the heterogeneous nature of gliomas, there is a risk of undergrading caused by histopathologic sampling errors. MRI has limitations in identifying tumor grade and type, detecting diffuse invasive growth, and separating recurrences from treatment induced changes. Positron emission tomography (PET) can provide quantitative information of cellular activity and metabolism, and may therefore complement MRI.

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Changing Operating Room Culture: Implementation of a Postoperative Debrief and Improved Safety Culture  Voir?

Patient safety is foundational to neurosurgical care. Postprocedural “debrief” checklists have been proposed to improve patient safety, but data about their use in neurosurgery are limited. Here, we implemented an initiative to routinely perform postoperative debriefs and evaluated the impact of debriefing on operating room (OR) safety culture.

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Preventing Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage with Aggressive Cisternal Clot Removal and Nicardipine  Voir?

A subarachnoid clot is the strongest predictor of cerebral vasospasm. Our purpose was to analyze the relationship between the number of postoperative cisternal clots and cerebral vasospasm and to assess the efficacy of surgical clot removal.
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Association of Perforator Infarction with Clinical Courses and Outcomes Following Surgical Clipping of Ruptured Anterior Communicating Artery Aneurysms  Voir?

Perforator infarction is a procedure-related complication of surgical clipping of ruptured anterior communicating artery (ACoA) aneurysms. Patients with perforator infarction may present with specific clinical features. The aim of this study was to elucidate incidence, risk factors, clinical course, and outcomes of perforator infarction following surgical clipping of ruptured ACoA aneurysms.

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Metastatic Basal Cell Adenocarcinoma of Submandibular Gland to the Spine: An Extremely Rare Condition  Voir?

Basal cell adenocarcinomas are rare malignant neoplasms of salivary glands, accounting for <1% of salivary gland tumors. Few cases of distant metastases have been reported.
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VITOM 3D: Preliminary Experience in Cranial Surgery  Voir?

Optimal vision and ergonomics are important factors contributing to achievement of good results during neurosurgical interventions. The operating microscope and the endoscope have partially filled the gap between the need for good surgical vision and maintenance of a comfortable posture during surgery. Recently, a new technology called video-assisted telescope operating monitor or exoscope has been used in cranial surgery. The main drawback with previous prototypes was lack of stereopsis. We present the first case report of cranial surgery performed using the VITOM 3D, an exoscope conjugating 4K resolution view and three-dimensional technology, and discuss advantages and disadvantages compared with the operating microscope.

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More Learning in Less Time: Optimizing the Resident Educational Experience with Limited Clinical and Educational Work Hours  Voir?

Resident education in the United States and elsewhere has undergone significant changes in recent years owing to work hour restrictions, requiring didactics to fit within a limited schedule, while being increasingly effective at accomplishing educational goals.
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Hybrid Technique for the Treatment of Refractory Vertebrobasilar Insufficiencies  Voir?

Tortuous or occluded vertebral arteries (VAs) can make the endovascular treatment of vertebrobasilar insufficiency impractical. Bypass surgery is an option, but a craniotomy of the posterior fossa is complicated when physiologic vessels must be abandoned. We report 3 cases of refractory vertebrobasilar insufficiency with different presentations requiring problematic approaches in which the patients were treated by different hybrid strategies.

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New Technique for Chiasmapexy Using Iliac Crest Bone Graft: 2 Cases of Visual Impairment Caused by Empty Sella Syndrome  Voir?

Chiasmapexy is used to treat empty sella syndrome, and various materials are used for the elevation of the optic chiasm. However, the use of artificial substances may have the risk of graft infection, and fat and muscle may be absorbed over the long term after surgery. In addition, bone and cartilage may be unavailable in adequate amounts. Here, we describe a new technique for chiasmapexy using an iliac crest bone graft.

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Recurrent Perimesencephalic Nonaneurysmal Subarachnoid Hemorrhage: Case Report and Review of the Literature  Voir?

Perimesencephalic nonaneurysmal subarachnoid hemorrhage (PNSAH) is a benign form of subarachnoid hemorrhage (SAH) with a favorable prognosis. The risk of recurrent hemorrhage of this benign entity is extremely low.
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Microelectrode Recording–Guided Versus Intraoperative Magnetic Resonance Imaging–Guided Subthalamic Nucleus Deep Brain Stimulation Surgery for Parkinson Disease: A 1-Year Follow-Up Study  Voir?

Microelectrode recording (MER) and intraoperative magnetic resonance imaging (iMRI) have been used in deep brain stimulation surgery for Parkinson disease (PD), but comparative methodology is lacking. Therefore, we compared the 1-year follow-up outcomes of MER-guided and iMRI-guided subthalamic nucleus (STN) deep brain stimulation (DBS) surgery in PD patients.

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Factors Predicting Ventricle Volume Increase After Aneurysmal Clipping in Patients with Subarachnoid Hemorrhage  Voir?

Although many studies have evaluated risk factors associated with hydrocephalus after aneurysmal subarachnoid hemorrhage, specific ventricle volume changes after subarachnoid hemorrhage have not been evaluated. We sought to evaluate factors predicting ventricle volume enlargement in patients with aneurysmal subarachnoid hemorrhage by measuring ventricle volume with a validated, semiautomated tool.

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Evaluation of Correction of Radiologic Parameters (Angulation and Displacement) and Accuracy of C2 Pedicle Screw Placement in Unstable Hangman's Fracture with Intraoperative Computed Tomography–Based Navigation  Voir?

Opinions vary regarding optimal treatment of unstable hangman's fractures, including rigid orthosis and internal fixation. The anatomy of upper cervical spine is complex. The advent of intraoperative 3-dimensional navigation systems facilitates safe and accurate instrumentation.
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Frozen Section Can “Sharpen” or “Sand Off” the Surgeon's Knife: 2 Case Illustrations with Skull Base Meningioma Mimics  Voir?

Lesions at the skull base warrant careful evaluation of imaging and meticulous preoperative planning. Unnecessary radical resection of these lesions could add to surgical morbidity. Occasionally, dural-based inflammatory or infectious lesions at this site radiologically mimic meningiomas, which are commonly encountered entities at this site. Not all lesions require excision, and it could be harmful in a few cases.

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Pattern of Corticospinal Projections Defined by Brain Mapping During Resective Epilepsy Surgery in a Patient with Congenital Hemiparesis and Intractable Epilepsy  Voir?

Congenital or early-onset brain structural lesions often cause contralateral hemiparesis, cognitive deficits, developmental delays, and seizures. Seizure is the most debilitating condition, as it greatly impairs quality of life in both the affected individuals and their caregivers and prevents them from active social participation.

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Staged Endovascular Occlusion of a Posterior Communicating Artery-Cavernous Sinus Fistula and a Basilar Artery-Cavernous Sinus Fistula Associated with Traumatic Pseudoaneurysms: Technical Consideration and Literature Review  Voir?

Traumatic injury of the posterior communicating artery or the basilar artery causing arteriovenous fistulae is rare.
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T1-T2 Herniated Disk Presenting with Horner Syndrome  Voir?

The incidence of thoracic disk herniation is estimated to be 1000 to 1,000,000. Upper thoracic disk herniation is an exceedingly rare pathology with unique neurologic features. We report a case of a young patient who presented with Horner syndrome caused by a T1-T2 disk herniation.
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The Management of Patients with Chronic Subdural Hematoma Treated with Low-Dose Acetylsalicylic Acid: An International Survey of Practice  Voir?

The aim of this international survey was to investigate the current management of patients undergoing surgery for chronic subdural hematoma (cSDH) treated with low-dose acetylsalicylic acid (ASA).
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Treatment of Syringomyelia in Patients with Arachnoiditis at the Craniocervical Junction  Voir?

Craniocervical junction arachnoiditis (CCJA) is an uncommon cause of syringomyelia. The pathophysiology of syrinx formation is uncertain, and the appropriate management unclear. A series of cases is reported to demonstrate variations in etiology, uniformity of functional cerebrospinal fluid obstruction at the foramen magnum, and results of surgical intervention.

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Endoscopic Endonasal Odontoidectomy with Anterior C1 Arch Preservation in Rheumatoid Arthritis: Long-Term Follow-Up and Further Technical Improvement by Anterior Endoscopic C1-C2 Screw Fixation and Fusion  Voir?

To examine the long-term outcomes (minimum of 4.5 years) of endoscopic endonasal odontoidectomy (EEO) with preservation of anterior C1 ring to treat irreducible ventral bulbo-medullary compressions in rheumatoid arthritis (RA) and to illustrate a novel technique of anterior pure endoscopic craniovertebral junction (CVJ) reconstruction and fusion. In fact, long-term clinical studies are still lacking to elucidate the effective role of EEO and whether it can obviate the need for posterior fixation.

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Innervation of the Anterior Sacroiliac Joint  Voir?

Sacroiliac joint pain can be disabling and recalcitrant to medical therapy. The innervation of this joint is poorly understood, especially its anterior aspect. Therefore, the present cadaveric study was performed to better elucidate this anatomy.
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“Wait-and-See” Strategies for Newly Diagnosed Intracranial Meningiomas Based on the Risk of Future Observation Failure  Voir?

To analyze factors affecting observation failure (Ob-F) of untreated intracranial meningiomas (IMs) and to develop a “wait-and-see” strategy for newly diagnosed IMs based on risk.
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Ventriculoscopic Approach for Intraventricular Neurocysticercosis: A Single Neurosurgical Center's Experience  Voir?

To retrospectively analyze patients with intraventricular neurocysticercosis (NCC) who underwent a ventriculoscopic approach at a single neurosurgical center and assess the efficacy of this treatment in patients with intraventricular NCC.
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Progression-Free Survival and Factors Associated with Postoperative Recurrence in 126 Patients with Atypical Intracranial Meningioma  Voir?

Atypical meningioma has a higher recurrence rate than benign meningioma. The mainstay of treatment is surgery with or without radiation therapy (RT). The objective of this study was to investigate progression-free survival (PFS) and factors associated with postoperative recurrence in patients with atypical meningioma.

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Transvenous Endovascular Treatment for Scalp Arteriovenous Fistulas: Results with Combined Use of Onyx and Coils  Voir?

Scalp arteriovenous fistulas (AVFs) are rare lesions that may occur spontaneously or secondary to head trauma. A standard treatment strategy for these lesions has not been established to date. We present 3 cases of successful treatment of scalp AVFs using a combination of Onyx-18 and coils via a transvenous approach.

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The Value of Short-Term Pain Relief in Predicting the Long-Term Outcome of Lumbar Transforaminal Epidural Steroid Injections  Voir?

A previous report demonstrated predictive power of short-term leg pain relief after lumbar transforaminal epidural steroid injections for 1-month treatment response. The question whether the long-term response could be similarly predicted remained unanswered.
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Endoscopic Third Ventriculostomy in Patients with Neurofibromatosis Type 1: A Multicenter International Experience  Voir?

Hydrocephalus in patients with neurofibromatosis (NF) type 1 is usually obstructive and may arise secondary to tumoral or nontumoral causes. Treatment of hydrocephalus in these patients is often challenging owing to combined pathologies and unique anatomic changes. The use of endoscopic third ventriculostomy (ETV) as treatment has rarely been described in this group. We aimed to characterize indications, considerations, and outcome of ETV in patients with NF 1 gathered in a multicenter international cohort.

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Three-Dimensional Cortical Surface Reconstruction Versus Operative Findings: Their Similarity and Applications  Voir?

Three-dimensional cortical surface reconstruction (3DCSR) is an important tool for operations involving cerebral cortex, but data on its similarity to actual cortical architecture are lacking. In this study, the authors systematically tested the similarity between operative findings and 3DCSR built by a neuronavigation system and illustrated its applications.

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Intraoperative Navigation Is Associated with Reduced Blood Loss During C1–C2 Posterior Cervical Fixation  Voir?

Traumatic injuries, degenerative/rheumatologic conditions, tumors, or infections of the upper cervical spine may in certain circumstances require surgical stabilization. C1 lateral mass screws (Harms technique) in combination with C2 instrumentation (pars, pedicle, translaminar screws) have become a mainstay of surgical treatment. The surgical anatomy of the C1 lateral mass can be challenging especially with the robust venous plexus that often causes significant bleeding with exposure of the C1–C2 articular complex.

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Mastoid Epidermoid Tumor and Associated Dural Arteriovenous Fistula with Venous Sinus Occlusion  Voir?

Dural arteriovenous fistula (DAVF) is an abnormal vascular connection between arterial and venous channels within dura mater. Although DAVFs have been linked to other types of intracranial tumors, this is the first case reporting the association between DAVF and an epidermoid tumor.
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Anatomy of Alar Ligament Part III: Biomechanical Study  Voir?

Four layers of ligamentous stabilizers comprise the craniocervical junction, and the second layer is composed of apical and paired alar ligaments. The purpose of this study is to establish the tensile strength of the alar ligaments for better understanding the implications that can arise from trauma and other pathologies in the craniocervical region.

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Medial Tentorial Dural Arteriovenous Fistula Embolization: Single Experience with Embolic Liquid Polymer SQUID and Review of the Literature  Voir?

Tentorial dural arteriovenous fistulas (DAVFs) are uncommon, complex fistulas located between the leaves of the tentorium cerebelli with a specific anatomic and clinical presentation characterized by high hemorrhagic risk. We present a rare case of a medial tentorial DAVF successfully managed via transarterial embolization using SQUID liquid polymer.

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Surgical Outcomes of Cavernous Sinus Syndrome in Pituitary Adenomas  Voir?

The type of pituitary adenoma with a manifestation that includes cavernous sinus syndrome is rare. Based on the clinical data of 70 patients, this study investigated the pathogenesis, imaging characteristics, and prognostic factors of pituitary adenoma with cavernous sinus syndrome.
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Identification of the Facial Nerve in Relation to Vestibular Schwannoma Using Preoperative Diffusion Tensor Tractography and Intraoperative Tractography-Integrated Neuronavigation System  Voir?

Preoperative visualization of the facial nerve could help neurosurgeons to prevent facial nerve injury during vestibular schwannoma surgery. Some studies have addressed diffusion tensor tractography (DTT) for preoperative identification of the facial nerve. However, few studies have focused on tractography-integrated neuronavigation for DTT verification. This study aimed to explore the appropriate DTT tracing parameters and evaluate the effect of intraoperative facial nerve tractography-integrated neuronavigation for verifying the DTT accuracy.

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Pilot Use of a Novel Tool to Assess Neurosurgical Capacity in Uganda  Voir?

There is a significant burden of unmet surgical need in many low- and middle-income countries (>80% in parts of Africa). This need is even larger for specialties such as neurosurgery. Surgical capacity tools have been developed and used to assess needs and plan for resource allocation. This study piloted a new tool to assess neurosurgical capacity and describes its use.

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Improvement of Quality of Life in Patients with Hemifacial Spasm After Microvascular Decompression: A Prospective Study  Voir?

Although not life threatening, hemifacial spasm (HFS) can be disabling and significantly affect quality of life (QOL). The aim of this study was to assess the major factors affecting the QOL and further to investigate the impact of microvascular decompression (MVD) on QOL in patients with HFS.
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Single-Center Experience of Mechanical Thrombectomy with the Trevo XP ProVue 6 × 25 mm Stent Retriever in Middle Cerebral Artery Occlusion: Comparison with Trevo XP ProVue 4 × 20 mm  Voir?

There are few studies assessing the suitable stent size for mechanical thrombectomy in middle cerebral artery (MCA) occlusion. We attempted to determine what size of stent is suitable for thrombectomy in MCA occlusion through a comparison of Trevo XP 6 × 25 mm and 4 × 20 mm stents.
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Anatomy of Alar Ligament Part I: Morphometrics and Variants  Voir?

The alar ligaments are among the primary ligamentous structures contributing to craniovertebral stability. The purpose of this study is to clarify the morphology of the alar ligament using fresh cadaveric specimens.
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Impact of Smartphone Applications on Timing of Endovascular Therapy for Ischemic Stroke: A Preliminary Study  Voir?

The metrics of imaging-to-puncture and imaging-to-reperfusion were recently found to be associated with the clinical outcomes of endovascular thrombectomy for acute ischemic stroke. However, measures for improving workflow within hospitals to achieve better timing results are largely unexplored for endovascular therapy. The aim of this study was to examine our experience with a novel smartphone application developed in house to improve our timing metrics for endovascular treatment.

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Surgical Resection and Cellular Proliferation Index Predict Prognosis for Patients with Papillary Glioneuronal Tumor: Systematic Review and Pooled Analysis  Voir?

Although the World Health Organization classifies papillary glioneuronal tumor (PGNT) as a grade I tumor, several malignant cases have been reported. In this study, we examined the clinical and prognostic characteristics of PGNT.
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Endovascular Thrombectomy Alone versus Combined with Intravenous Thrombolysis  Voir?

To date, no randomized trial has directly addressed the question of whether intravenous (IV) tissue plasminogen activator (tPA) improves outcomes in IV tPA-eligible patients who will eventually undergo endovascular therapy (EVT), or whether a direct EVT strategy is equally effective. We performed a systematic review and meta-analysis to compare the efficacy and safety of direct EVT versus endovascular treatment with IV tPA (EVT+IV tPA) in adults with acute ischemic stroke.

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Anatomic Variations of the Anterior Atlantodental Joint and Relations to the Apical and Alar Ligaments in a Geriatric Population  Voir?

Degenerative changes in the upper cervical spine may be age related degeneration or a pathological process such as rheumatoid arthritis. However, to our knowledge, the relationship between the apical and alar ligaments and these anomalies has not been discussed. We present anatomical variations of the anterior atlantodental joint observed during cadaveric dissection of adult craniovertebral junctions, the relationship with the alar and apical ligaments and discuss possible origins and clinical implications.

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Calcified Spinal Meningioma: A Lurking Danger  Voir?

Tumors of the spine with an intradural location have an incidence ranging from 3 to 10 per 100,000 persons per year, and intradural extramedullary tumors account for two thirds of all intraspinal neoplasms.1 Among these, spinal meningiomas account for 25%–46% of all spinal cord tumors.2 They develop from the arachnoid cells that differentiate from neural crest cells and, like cerebral meningioma, they have a slow-growing behavior. Although spinal meningiomas are not uncommon, calcified spinal meningioma is rare in spinal location.

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One of the Earliest Accounts of Head Wounds in Firdaws al-Ḥikma by al-Ṭabarī from the 9th Century  Voir?

To present the first Arabic text on suturing scalp wounds.
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Thoracic Arachnoid Cyst Made Symptomatic by Demyelination  Voir?

Spinal arachnoid cysts are uncommon distinct pouches of cerebrospinal fluid (CSF) or CSF-like fluid found adjacent to normal CSF spaces commonly extradural and rarely intradural. They are usually asymptomatic and discovered incidentally. We present a patient with rapid upper motor neuron neurologic deterioration over the course of 1 week. Findings on magnetic resonance imaging revealed various central nervous system demyelination lesions and thoracic arachnoid cyst with cord compression. This acute presentation, in the absence of trauma, is not in favor of the natural history of the intradural thoracic arachnoid cysts.

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Nontuberculous Antineutrophil Cytoplasmic Antibody–Positive Pachymeningitis Presenting as High Cervical Myelopathy  Voir?

High cervical myelopathy is a common entity and often encountered in clinical practice. Various pathologies can present with this symptomatology. Detailed history and a meticulous neurological examination can help us differentiate and rule out some of the close differentials. Non tuberculous ANCA positive pachymeningitis is a rare entity and a diagnosis of exclusion or following histopathological confirmation. Here we describe a case of high cervical myelopathy, the presentation, imaging and the various differentials considered and how we arrived at the diagnosis.

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Risk of Complications with Simultaneous Cranioplasty and Placement of Ventriculoperitoneal Shunt  Voir?

The development of hydrocephalus (HCP) necessitating placement of a ventriculoperitoneal shunt (VPS) after decompressive hemicraniectomy occurs at a rate of approximately 5%–15%. The ideal approach for addressing both HCP and a cranial defect remains unclear, and whether concomitant VPS and cranioplasty (CP) increases the risk of complications is uncertain.

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Surgical Management of Hemifacial Spasm Associated with Chiari I Malformation: Analysis of 28 Cases  Voir?

Hemifacial spasm (HFS) associated with Chiari I malformation (CIM) is rare. This study aimed to analyze the frequency of HFS associated with CIM in our department and further to investigate the clinical characteristics, treatment strategies, and outcomes of these cases.
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Neurosurgical “Squeeze Play”: Single Incision with Dual Ipsilateral Craniotomies Versus 2 Separate Approaches for Intracranial Aneurysm Treatment  Voir?

Patients with bilateral, multiple intracranial aneurysms (IA) can be safely treated using 1 lateral craniotomy. However, in patients with an additional pericallosal artery (PcaA) or distal anterior cerebral artery (ACA) aneurysm, an interhemispheric approach through a bifrontal craniotomy is needed. We investigated the safety of a single incision with dual ipsilateral craniotomies (“squeeze play”) and compared results with 2 separate staged surgeries.

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Intradural-Extramedullary Capillary Hemangioma with Acute Bleeding: Case Report and Literature Review  Voir?

Capillary hemangiomas are benign vascular tumors. They are commonly founded in the vertebral bodies but very seldom in the spinal cord. The most common symptom at onset is long-lasting axial pain without neurologic deficit. In rare cases, the onset may be acute with neurological deficit due to an intratumoral hemorrhage.

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Rescue Implantation of Expandable Cages for Severe Osteolysis and Cage Dislocation in the Lumbosacral Junction  Voir?

Osteolysis and implant loosening are commonly encountered problems after spinal instrumentation.
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Operative Complications of Microvascular Decompression for Hemifacial Spasm: Experience of 1548 Cases  Voir?

Although microvascular decompression (MVD) surgery is considered the gold standard treatment for hemifacial spasm, there are some MVD-related complications.
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Long-Term Outcome and Prognostic Factors After Repeated Surgeries for Intracranial Hemangiopericytomas  Voir?

The goals of the present study were to identify predictors of better survival and to propose appropriate management strategies for recurrent hemangiopericytomas (HPC) and anaplastic hemangiopericytomas (AHPC).
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Application of 3-Dimensional Printing in a Case of Osteogenesis Imperfecta for Patient Education, Anatomic Understanding, Preoperative Planning, and Intraoperative Evaluation  Voir?

The techniques and applications of 3-dimensional (3D) printing have progressed at a fast pace. In the last 10 years, there has been significant progress in applying this technology to medical applications. We present a case of osteogenesis imperfecta in which treatment was aided by prospectively using patient-specific, anatomically accurate 3D prints of the calvaria. The patient-specific, anatomically accurate 3D prints were used in the clinic and in the operating room to augment patient education, improve surgical decision making, and enhance preoperative planning.

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Body Mass Index >35 as Independent Predictor of Mortality in Severe Traumatic Brain Injury  Voir?

Severe traumatic brain injury (TBI) has a major influence on polytrauma outcome. The aim of this study was to evaluate the impact of body mass index (BMI) on mortality and early neurologic outcome in patients suffering from severe TBI with a special focus on obesity classes II and III (BMI ≥35).
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Endovascular Management of Ruptured Distal Anterior Cerebral Artery (DACA) Aneurysms: A Retrospective Review Study  Voir?

Distal anterior cerebral artery (DACA) aneurysms are rare, and their treatment by either surgical clipping or endovascular treatment poses technical difficulties. Earlier studies have reported higher complication rates in DACA aneurysms compared with other aneurysms in the circle of Willis. Therefore, endovascular management of DACA aneurysms still remains a challenge. The aim of this report is to review clinical presentation, angiographic presentation of DACA aneurysms, complications, and outcome of their endovascular treatment in our institutional experience.

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Characterization of Pyramidal Tract Shift in High-Grade Glioma Resection  Voir?

This study aimed to characterize pyramidal tract shift in different regions of the brain during glioma resection and its association with head position and tumor location.
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Anterior Lumbar Dural Tear: A Transthecal Route for Primary Closure After Iatrogenic Durotomy  Voir?

Durotomies are not infrequent in spine surgery and have increased complication rates. Primary repair is the gold standard and is feasible when access is not limited by the anatomy. A patient who presented 1 week after spinal fusion with cerebrospinal fluid (CSF) leak underwent a novel transthecal approach to repair an anterior dural tear.

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Bilateral Temporal Myofascial Flap for the Reconstruction of Frontal Sinus Defects  Voir?

A frontal sinus infection, following a transsinus skull base procedure, portends potentially life-threatening complications, making surgical revision mandatory in refractory infections. The authors describe the application of the bilateral temporal myofascial flap (BTMF) as a valuable option for frontal sinus reconstruction, when pericranial or galeal-frontalis myofascial flap (GFMF) is no longer available.

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Syringo-Subarachnoid Shunt for the Treatment of Persistent Syringomyelia Following Decompression for Chiari Type I Malformation: Surgical Results  Voir?

Approximately 30% of patients treated with foramen magnum decompression (FMD) for Chiari I–associated syringomyelia will show persistence, recurrence, or progression of the syrinx.
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Open Versus Minimally Invasive Surgery for Extraforaminal Lumbar Disk Herniation: A Systematic Review and Meta-Analysis  Voir?

Extraforaminal disk herniation (EDH) accounts for 3%–11% of all disk herniations. Despite the heterogeneity of spinal procedures, there is a paucity of literature comparing the outcomes from different surgical approaches.
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The Top-100 Most-Cited Articles on Meningioma  Voir?

There is an abundance of articles published on meningioma.
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Cell Therapy as a New Approach to the Treatment of Posttraumatic Syringomyelia  Voir?

Cell transplantation with autologous bone marrow–derived mesenchymal stromal cells (MSCs) seems to be a therapeutic promise for patients with established spinal cord injury, achieving improvement in their quality of life, but there is no experience with the application of this type of cell therapy in patients suffering posttraumatic syringomyelia.

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Unusual Magnetic Resonance Imaging Findings of a Glioblastoma Arising During Treatment with Lenvatinib for Thyroid Cancer  Voir?

Glioblastoma (GBM) is a lesion radiologically characterized by magnetic resonance imaging findings, such as ring enhancement with extensive perifocal edema and a butterfly appearance extending into the bilateral lobes. However, these characteristic findings could be changed by antiangiogenic therapy, with decreased contrast enhancement and improved perifocal edema. Herein, we report a case of GBM that arose during treatment with a tyrosine kinase inhibitor for another cancer.

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Subependymomas Are Low-Grade Heterogeneous Glial Neoplasms Defined by Subventricular Zone Lineage Markers  Voir?

Subependymomas are infrequent, low-grade gliomas associated with the ventricular system and the spinal cord. Little is known about the origin and natural history of these slow-growing lesions.
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Four-Hand Suction-Irrigation Technique Leads to Gross Total Resection and Long-Term Progression-Free Survival in Fourth Ventricular Ependymoma  Voir?

Gross total resection is often avoided in posterior fossa ependymoma surgery because of the fear of permanent neurologic deficits after operation. However, the extent of resection is a major prognostic factor for progression-free and overall survival. This study evaluates the outcome of posterior fossa ependymoma gross total resection in adult patients using a 4-hand suction-irrigation technique at the floor of the fourth ventricle.

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Real-Time Ultrasound Doppler Enhances Precision in Image-Guided Approaches to the Cerebellopontine Angle  Voir?

To evaluate efficacy and reliability of intraoperative Doppler sonography in localizing the transverse and sigmoid sinuses during lateral suboccipital craniotomy.
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Easy, Efficient, and Mobile Way to Train Microsurgical Skills During Busy Life of Neurosurgical Residency in Resource-Challenged Environment  Voir?

Residents' lives are hectic—it is hard to find a place and time for training basic and advanced microsurgical skills. Surgical instruments and sutures can be purchased (or loaned from another department), but the most expensive and space-occupying device is the microscope. In developing countries, microscopes are used where they are needed most, in operating rooms. Furthermore, a conventional microscope is not portable. For all of these reasons, the availability of microscopes for training microsurgery is limited.

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Metastatic Cardiac Angiosarcoma to the Lung, Spine, and Brain: A Case Report and Review of the Literature  Voir?

Metastatic angiosarcoma to the brain is a rare entity without an established management protocol.
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Ruptured Vertebral Artery Dissecting Aneurysm Concurrent with Spontaneous Cervical Internal Carotid Artery Dissection: A Report of Three Cases and Literature Review  Voir?

Multiple dissections rarely occur with ruptured vertebral artery dissecting aneurysms (VADAs). Here we report 3 cases of ruptured VADA concurrent with spontaneous cervical internal carotid artery (ICA) dissection.
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Seeding of Abdomen with Primary Intracranial Hemangiopericytoma by Ventriculoperitoneal Shunt: Case Report  Voir?

Ventriculoperitoneal shunt (VPS) placement has been implicated in extraneural metastasis of many primary central nervous system tumors. Reported cases include, but are not limited to, medulloblastoma, germ cell tumor, astrocytoma, oligodendroglioma, lymphoma, ependymoma, melanoma, and choroid plexus tumors. However, a literature review reveals no reported cases of extraneural metastasis of solitary fibrous tumor/hemangiopericytoma (SFT/HPC).

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Influence of Obesity on Complications, Clinical Outcome, and Subsidence After Anterior Lumbar Interbody Fusion (ALIF): Prospective Observational Study  Voir?

The complications associated with obesity have been well described for posterior lumbar spinal surgery. However, the influence of obesity on anterior lumbar interbody fusion (ALIF) is not well established. We aimed to compare complication risks, functional outcomes, and subsidence rates in normal-weight, overweight, and obese patients who underwent ALIF.

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IgG4-Related Disease: A New Etiology Underlying Diffuse Intracranial Dilating Vasculopathy  Voir?

Diffuse intracranial aneurysmal vasculopathy is a rare condition, previously described in patients with human immunodeficiency virus infection. IgG4-related disease (IgG4-RD) is a recognized inflammatory disease of systemic organs, leading to fibrosis of connective tissues. It also has been linked to inflammatory dilating aortic aneurysms, coronary vascular disease, hypophysitis, orbital pseudotumor, and pachymeningitis. It has not yet been described as a cause of diffuse intracranial dilating vasculopathy.

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Intraoperative Vascular Neuromonitoring in Patients with Subarachnoid Hemorrhage: A Pilot Study Using Combined Laser-Doppler Spectrophotometry  Voir?

Intraoperative monitoring of cerebral microcirculation in patients with subarachnoid hemorrhage (SAH) may predict the postoperative neurologic outcome. In this pilot study, we examined the value of a novel noninvasive real-time measurement technique for detecting changes in local microcirculation.
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Treatment of Unstable Thoracolumbar Fractures: Does Fracture-Level Fixation Accelerate the Bone Healing?  Voir?

To investigate the effect of fusion on short segment including fractured level (SSIFL) and long segment (LS) transpedicular fixation after acute thoracolumbar junction burst fractures. The 2-year clinical and radiologic follow-up results of the 2 groups also were compared.
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Clusterin, a New Cerebrospinal Fluid Biomarker in Severe Subarachnoid Hemorrhage: A Pilot Study  Voir?

Inflammation following subarachnoid hemorrhage (SAH) involves numerous mediators with biomarker properties. Preliminary studies indicated that clusterin, a multifunctional chaperon protein, was a potential biomarker in SAH. We aimed to clarify the status of clusterin in SAH.
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Anatomy of the Alar Ligament: Part II: Variations of Its Attachment onto the Dens  Voir?

Various authors have described the morphology of the alar ligaments; however, there are no reports of a cadaveric study focusing on their attachments onto the dens. The purpose of this study was to use fresh cadaveric specimens to describe in detail different attachment patterns of the alar ligaments onto the dens.

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Bevacizumab Plus Radiosurgery for Nonsquamous Non–Small Cell Lung Cancer Patients with Brain Metastases: Safe Combination?  Voir?

In the context of bronchial cancers, the brain is one of the most frequent sites for metastases. Local treatments of these metastases have evolved and are often combined to obtain greater efficiency, while the main objective remains to reduce the symptoms. Radiosurgery is currently used as a primary option for patients harboring few numbers of small to middle-sized brain metastases. In nonsquamous non–small cell lung cancer (NSCLC), chemotherapy is often associated with bevacizumab. Our goal was to assess the safety of this early combination.

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Stereotactic Radiosurgery for Dural Arteriovenous Fistulas without Cortical Venous Reflux  Voir?

The rationale for treatment of dural arteriovenous fistulas (dAVFs) without cortical venous reflux is symptomatic resolution. Most studies of dAVF treatment, including those for stereotactic radiosurgery, have focused on angiographic obliteration instead of clinical symptomatic outcome.
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Fatal Colloid Cysts: A Systematic Review  Voir?

To accurately describe patient characteristics and the clinical presentation of fatal colloid cysts.
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Ewing Sarcoma of the Cervical Epidural Space Presenting with Tetraplegia: Case Report and Review of Literature  Voir?

Ewing sarcoma (ES) is among the most frequented extremity osseous tumor in childhood. It was first described by James Ewing as diffuse endotheliomas in 1921. The name Ewing sarcoma was coined by Oberling in 1928 as a tribute to the legend who described this disease. ES exists in osseous and extraosseous forms. It shares much of its molecular typing with primitive neuroectodermal tumor (PNET); hence, they are regarded as different ends of the same molecular spectrum. ES, extraosseous ES, PNET, and Askins tumor are the other members of this family termed the Ewing sarcoma family of tumors.

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Rhabdoid Meningioma Arising Concurrent in Pulmonary and Intracranial with a Rare Malignant Clinical Progression: Case Report and Literature Review  Voir?

Rhabdoid meningioma (RM) is an unusual variant of meningioma, classified as World Health Organization grade III. Although its recurrence is common, extracranial metastasis is rare and usually misdiagnosed. The transfer mechanism and pathway are ambiguous; once the metastasis occurs, the prognosis is poor, and there is no effective management. The present case is the first report of concurrent intracranial and pulmonary RM with rapid and widespread metastasis. We hope this report can serve as a helpful reference for clinicians and radiologists.

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Rationalization of the Irrational Neuropathologic Basis of Hypothyroidism-Olfaction Disorders Paradox: Experimental Study  Voir?

Hypothyroidism is defined as an underactive thyroid gland and one of the reasons for inadequate stimulation of thyroid is dysfunction of the hormone regulating brain centers. Olfaction disorders have been considered as a problem in hypothyroidism. It has been hypothesized that olfaction disorders reduce olfactory stimulation and diminished olfactory stimulus may trigger hypothyroidism. In this study, an examination was made of the thyroid hormone levels, histologic features of thyroid glands, and vagal nerve network degradation in an experimental animal model of olfactory bulbectomy (OBX).

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Correlation of Circulating T Lymphocytes and Intracranial Hypertension in Intracerebral Hemorrhage  Voir?

The close correlation between intracerebral pressure (ICP) and immunologic responses has been well described, but the role of T lymphocytes in this process remains unknown. This study targeted the relationship of circulating T lymphocytes and ICP in patients with intracerebral hemorrhage (ICH).
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Variation in Psoas Muscle Location Relative to the Safe Working Zone for L4/5 Lateral Transpsoas Interbody Fusion: A Morphometric Analysis  Voir?

The safe working zone for lateral access to the L4/5 disc space has been said to lie in the anteroposterior (AP) midpoint of the disc space due to the location of the femoral nerve at that level. However, the AP location of the psoas muscle (and thus the lumbosacral plexus within) at L4/5 is variable. A psoas muscle lying excessively anteriorly at the L4/5 disc space may preclude safe access to the L4/5 disc space from a lateral transpsoas approach.

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Identification of Preoperative and Intraoperative Risk Factors for Complications in the Elderly Undergoing Elective Craniotomy  Voir?

Neurosurgical patients are aging as the general population is becoming older.
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Characterization of a Factual Knowledge–Associated Brain Memory Area by Functional Magnetic Resonance Imaging and Implementation in Tumor and Epilepsy Brain Surgery  Voir?

The role of the dominant hippocampus in verbal and episodic memory recall has been extensively investigated. However, there are categories of memory estimated independent of hippocampal function. In particular, factual knowledge is solely constituted from written or spoken input independent on undertaken experience, but the temporal structures involved are not well defined.

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Physiologic Mechanisms of Water and Electrolyte Disturbances After Transsphenoidal Pituitary Surgery  Voir?

Disturbances in water and electrolyte homeostasis are common after transsphenoidal surgery. These disorders are variable and unpredictable, increasing patient risk and complicating postsurgical treatment. Clinically, it is generally accepted that damage to the pituitary is the cause, but the mechanisms behind the response variability and underlying pathophysiology remain unknown.

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Can Fan-Beam Interactive Computed Tomography Accurately Predict Indirect Decompression in Minimally Invasive Spine Surgery Fusion Procedures?  Voir?

Recently, novel mobile intraoperative fan-beam computed tomography (CT) was introduced, allowing for real-time navigation and immediate intraoperative evaluation of neural decompression in spine surgery. This study sought to investigate whether intraoperatively assessed neural decompression during minimally invasive spine surgery (MISS) has a predictive value for clinical and radiographic outcome.

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Frontal Fibers Connecting the Superior Frontal Gyrus to Broca Area: A Corticocortical Evoked Potential Study  Voir?

The frontal aslant tract is a deep frontal pathway connecting the superior frontal gyrus (SFG) to Broca area. This fiber is assumed to be associated with language functions, especially speech initiation and spontaneity. The aim of this study was to electrophysiologically investigate this network using corticocortical evoked potentials (CCEPs).

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A Portable Training Model for Deep Bypass Surgery  Voir?

Deep bypass surgery remains a challenging operative procedure. For novice trainees, there is a high barrier to improving the microsurgical skills needed for this procedure because of the relatively low number of cases and the high cost of microsurgical instruments. Here, the authors introduce a training model that includes highly accessible devices and does not require a microscope.

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Varied Spectrum of Supratentorial Arteriovenous Malformations: Technical Challenges  Voir?

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Reduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients  Voir?

Smoking status has been shown to affect postoperative outcomes after surgery. The aim of this study was to determine whether patients' smoking status impacts 30-day complication and readmission rates after elective complex spinal fusion (≥3 levels).
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Cervical Paraspinal Muscle Atrophy Rates Following Laminoplasty and Laminectomy with Fusion for Cervical Spondylotic Myelopathy  Voir?

Cervical spondylotic myelopathy (CSM) is a disorder that can cause neurologic deterioration. Studies on paraspinal muscular atrophy (PMA) in the lumbar spine have shown that these changes are caused by several perioperative factors. It is possible that PMA in the cervical spine could behave similarly. In this retrospective study, we compared the degree of PMA after laminoplasty versus laminectomy and fusion (LF) using a standard posterior approach to the cervical spine.

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A Modified Technique for Occipitocervical Fusion Using Compressed Iliac Crest Allograft Results in a High Rate of Fusion in the Pediatric Population  Voir?

In children, high rates of occipitocervical (OC) fusion have been demonstrated with the use of rigid instrumentation in combination with harvested autograft, with or without bone morphogenetic protein (BMP). Historically, the use of allograft materials demonstrated inferior OC fusion outcomes compared with autograft. However, autograft harvest harbors an increased risk of patient morbidity, and the use of BMP is costly and controversial in children. Thus, there remains a need for safer, less costly, yet efficacious techniques for OC fusion in the pediatric population.

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Increased Ratio of Superficial Temporal Artery Flow Rate After Superficial Temporal Artery-to-Middle Cerebral Artery Anastomosis: Can It Reflect the Extent of Collateral Flow?  Voir?

There are several ways to identify donor artery patency and success of surgery after an anastomosis of the superficial temporal artery (STA) to the middle cerebral artery (MCA). The purpose of this study was to evaluate the ratio of bilateral STA mean flow rate (MFR) with the use of color Doppler ultrasonography (CDUS) after bypass surgery and to confirm the possibility of this value as a predictor of the extent of collateral flow.

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The Relationship Between the Direction of Putaminal Intracerebral Hemorrhage and Anterior Cerebral Artery Predominance  Voir?

It is expected that anatomic variations in the circle of Willis have a direct effect on blood flow in the internal carotid artery. Rupture of the lenticulostriate artery of the middle cerebral artery 1st segment (M1) is the most common cause of putaminal intracerebral hemorrhage (ICH), and we hypothesized that this could be related to the anatomic variations of the circle of Willis and the predominance of the anterior cerebral artery 1st segment (A1).

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Targeted Epidural Blood Patch Under O-Arm–Guided Stereotactic Navigation in Patients with Intracranial Hypotension Associated with a Spinal Cerebrospinal Fluid Leak and Ventral Dural Defect  Voir?

Targeted epidural blood patch (EBP) at the site of a presumed cerebrospinal fluid leak reportedly has better outcomes than non-targeted EBP; however, it is associated with a higher risk of wrong-site injection, such as iatrogenic subarachnoid or intramuscular injections, which lead to reintervention because of the insufficient coverage of injected blood.

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Relationship Among Koenig Depression Scale and Postoperative Outcomes, Ambulation, and Perception of Pain in Elderly Patients (≥65 Years) Undergoing Elective Spinal Surgery for Adult Scoliosis  Voir?

The aim of this study was to assess whether the Koenig Depression Scale (KDS) can identify depressed elderly patients undergoing elective spine surgery for deformity at risk for inferior postoperative outcomes including complication rates, ambulation ability, and patient-reported outcomes.
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Surgical Management of Rathke Cleft Cysts  Voir?

The diagnosis of Rathke cleft cysts (RCC) has increased in recent times as a result of improvements in imaging techniques; however, symptomatic patients are uncommon and accurate preoperative diagnosis may sometimes be difficult. The indications of surgical management protocol are evolving. We aim to provide a comprehensive review of clinical, imaging, and histopathologic features with operative management strategies along with outcome and prognosis in RCC.

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Biomechanical Analysis of Bilateral Facet Joint Stabilization Using Bioderived Tendon for Posterior Cervical Spine Motion Reservation in Goats  Voir?

To investigate the biomechanical properties of a novel stabilization method for posterior cervical motion preservation using bioderived freeze-dried tendon.
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Surgical Decompression for Chiari Malformation Type I: An Age-Based Outcomes Study Based on the Chicago Chiari Outcome Scale  Voir?

There is currently inadequate evidence on the efficacy of surgical decompression for Chiari malformation type I (CM1) in different age groups of patients. In this study, we compared postoperative outcomes across 3 different age groups using the Chicago Chiari Outcome Scale (CCOS).
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Occlusion Status on Magnetic Resonance Angiography Is Associated with Risk of Delayed Ischemic Events in Cerebral Aneurysms Treated with Stent-Assisted Coiling  Voir?

Management after stent-assisted coiling (SAC) for unruptured intracranial aneurysm is sometimes difficult because close monitoring for ischemic events for a long period of time after the procedure is necessary. The purpose of this study was to clarify the usefulness of magnetic resonance angiography (MRA) at follow-up after SAC.

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Head Computed Tomography Scan in Isolated Traumatic Brain Injury in a Low-Income Country  Voir?

Head computed tomography scan (HCTS) is the cornerstone of the management of traumatic brain injury (TBI). The impact of performing a HCTS in TBI has been scarcely investigated in low-income countries (LICs). Furthermore, the cost of a HCTS is a burden for family finances.
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Modified Posterior C1 Lateral Mass Screw Insertion for Type II Odontoid Process Fractures Using Intraoperative Computed Tomography–Based Spinal Navigation to Minimize Postoperative Occipital Neuralgia  Voir?

Various surgical techniques have been described for treating odontoid instability and achieving effective stabilization. The earliest technique to be described proposed a C1 lateral mass entry point including neurectomy of the C2 nerve roots to ensure hemostasis. Because C2 neurectomy remains controversial, preservation of the C2 nerve root as described in Goel-Harms technique can lead to intractable occipital neuralgia and significant blood loss. The aim of this study was to modify the Goel-Harms technique with a high C1 lateral mass screw entry point to enhance overall intraoperative safety.

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Internal Maxillary Artery to Upper Posterior Circulation Bypass Using a Superficial Temporal Artery Graft: Surgical Anatomy and Feasibility Assessment  Voir?

Revascularization of the upper posterior circulation (UPC), including the superior cerebellar artery (SCA) and posterior cerebral artery (PCA), may be necessary as part of the surgical treatment of complex UPC aneurysms or vertebrobasilar insufficiency. The existing bypass options have relative advantages and disadvantages. However, the use of a superficial temporal artery graft (STAg) in a bypass from the internal maxillary artery (IMA) to the UPC has not been previously assessed. We studied the surgical anatomy and assessed the technical feasibility of the IMA-STAg-UPC bypass.

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Flow Diversion and Outcomes of Vertebral Fusiform Aneurysms After Stent-Only Treatment: A Hemodynamic Study  Voir?

The aim of this study was to determine the effectiveness of treating vertebral fusiform aneurysms (VFAs) only with stents. Using computational fluid dynamics, we evaluated the hemodynamic patterns of VFAs after stent-only treatment (SOT) and monitored hemodynamic changes in the side branches.
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Preservation of Motor Function After Resection of Lower-Grade Glioma at the Precentral Gyrus and Prediction by Presurgical Functional Magnetic Resonance Imaging and Magnetoencephalography  Voir?

Intra-axial brain tumors located at anatomically eloquent areas are challenging conditions. On one hand, it is often difficult to pursue maximum extent of resection of tumor in these locations. On the other hand, neuroplasticity occurs in some patients with low-grade glioma, and the primary neural functions are known to sometimes shift from conventional “eloquent cortices.”

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Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report  Voir?

Intramedullary ependymal cysts of the spinal cord are rare, benign, fluid-filled cysts usually situated along the ventral surface of the spinal cord. Only 32 cases have been reported since they were first described. Thus, owing to the rarity at which these cysts are encountered, their management and pathogenesis remain controversial. Whereas some investigators have advocated for cystosubarachnoid shunt placement for symptomatic ependymal cysts, others have argued for complete cyst resection or simple fenestration.

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Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle in Children: Case Report and Literature Review  Voir?

Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a rare World Health Organization (WHO) grade I neoplasm. Gross total resection (GTR) is the treatment of choice, and there is no firm evidence supporting other treatment options when GTR is not feasible.
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The Application of a Three-Dimensional Printed Product to Fill the Space After Organ Removal  Voir?

Maintaining body integrity, especially in Asian societies, is an independent predictor of organ donation.
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Predictive Factors of Unfavorable Events After Gamma Knife Radiosurgery for Vestibular Schwannoma  Voir?

Gamma Knife radiosurgery (GKS) for the treatment of vestibular schwannoma (VS) introduces risks to the facial nerve and auditory perception and may involve post-treatment complications such as pseudoprogression, hydrocephalus, and other cranial neuropathies. This study of patients with VS who underwent GKS investigated radiosurgical results, focusing on post-treatment complications and identifying the factors that predict such complications.

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First Case of Autonomic Dysreflexia Following Elective Lower Thoracic Spinal Cord Transection in a Spina Bifida Adult  Voir?

Spinal cord transection is a radical but effective treatment for highly selective cases of symptomatic spinal retethering in paraplegic spina bifida patients. Autonomic dysreflexia (AD) is a potentially life-threatening syndrome involving a dysregulated sympathetic discharge reflex commonly seen following cervical and high thoracic spinal cord injury, leading to a disconnect between autonomic pathways above and below the lesion that can lead to severe complications including uncontrolled hypertension, bradycardia, stroke, and potentially death.

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Flow Diverter Treatment of Tandem Intracranial Aneurysms  Voir?

To assess technical success and clinical and imaging outcomes of flow diversion (FD) treatment of multiple, tandem intracranial aneurysms.
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Urinary F2-Isoprostane Concentration as a Poor Prognostic Factor After Subarachnoid Hemorrhage.  Voir?

The role of isoprostanes in cerebral vasospasm (CVS) following aneurysmal subarachnoid hemorrhage (aSAH) is controversial. Recent studies have suggested that the level of isoprostanes in cerebrospinal fluid could play a role in outcomes of patients with aSAH. We measured concentration of urinary F2-isoprostanes (F2-IsoPs), which is simple and noninvasive.

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Biocompatible Amniotic Sac Implant Maintains a Scar-Free Brain Surface During Recurrent Glioma Surgery  Voir?

Dissection of brain surface adhesions during recurrent glioma surgery carries a risk of injury to cortical vessels and important surface vessels. We present our experience with the use of BioD film, a biocompatible amniotic membrane implant, to help prevent postoperative adhesions. We describe a novel method for preventing postoperative adhesions after high-grade glioma surgery using BioD film.

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Forgotten? Not Yet. Cardiogenic Brain Abscess in Children: A Case Series–Based Review  Voir?

Brain abscess is a significant cause of morbidity in patients with uncorrected or partially palliated congenital cyanotic heart disease (CCHD). Unfortunately, in the developing world, the majority of patients with CCHD remain either uncorrected or only partially palliated. Furthermore, a risk of this feared complication also exists even among those undergoing staged corrective operations in the interval in between operations. There have been no recent articles in the literature on the outcomes of surgical management of cardiogenic brain abscess in children.

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Correlation of Aggressive Intracranial Lesions and Venous Reflux Patterns in Dural Arteriovenous Fistulas  Voir?

The association between venous reflux patterns with aggressive intracranial lesions (AILs), including intracranial edema (IE), intraparenphymal hemorrhage (IPH), and subarachnoid hemorrhage (SAH), has not been well established in cranial dural arteriovenous fistulas (DAVFs). We propose an updated classification system based on venous drainage.

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The Likelihood of Remnant Nonfunctioning Pituitary Adenomas Shrinking Is Associated with the Lesion's Blood Supply Pattern  Voir?

Nonfunctioning pituitary adenomas (NFPA) often shrink after transsphenoidal surgery. However, little is known about the predictors of spontaneous NFPA regression. The aim of this study was to determine whether the blood supply pattern of remnant NFPA lesions was associated with the likelihood of such lesions shrinking.

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Malignant Cerebral Swelling After Cranioplasty due to Ipsilateral Intracranial Vasculopathy: Case Report and Literature Review  Voir?

Cranioplasty is a well-established surgical operation that is used worldwide for patients with skull defects following decompressive craniectomy (DC). However, in some cases, potentially fatal complications may occur, such as malignant cerebral swelling after uneventful cranioplasty.
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Local Fibrinolytic Therapy for Intraventricular Hemorrhage: A Meta-Analysis of Randomized Controlled trials  Voir?

The safety and efficacy of intraventricular fibrinolysis (IVF) in patients with intraventricular hemorrhage (IVH) are unclear. We aimed to determine these issues and to evaluate whether there are differences between recombinant tissue-plasminogen activator (rt-PA) and urokinase according to subgroup analyses.

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Linguistic Validation of Interactive Educational Interventions in Neurologic Trauma  Voir?

Neurological surgeons oftentimes educate patients and their families on complex medical conditions and treatment options. Time constraints and varied linguistic and cultural backgrounds limit the amount of information that can be disbursed. In this study, we assessed the linguistic validity of interactive educational interventions in non-English-speaking patients with traumatic brain injury (TBI) and concussion and their families.

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Degree and Duration of Functional Improvement on Long-Term Follow-Up of Spinal Dural Arteriovenous Fistulae Occluded by Endovascular and Surgical Treatment  Voir?

Long-term outcomes following occlusion of spinal dural arteriovenous fistula (SDAVF) are poorly understood and are based on small series reporting predominantly short-term outcomes. The degree and duration of improvement remain unclear. In this study, we analyzed long-term outcomes following occlusion in a cohort of patients with SDAVF.

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Anatomic Targeting of the Optimal Location for Thalamic Deep Brain Stimulation in Patients with Essential Tremor  Voir?

Thalamic deep brain stimulation (DBS) is an effective strategy for treatment of essential tremor (ET). With limitations of imaging modalities, targeting largely relies on indirect methods. This study was designed to determine the optimal target for DBS in ET and construct a targeting method based on probabilistic maps.

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Epidemiology of Mild Traumatic Brain Injury with Intracranial Hemorrhage: Focusing Predictive Models for Neurosurgical Intervention  Voir?

To outline differences in neurosurgical intervention (NI) rates between intracranial hemorrhage (ICH) types in mild traumatic brain injuries and help identify which ICH types are most likely to benefit from creation of predictive models for NI.
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Reevaluation of Classic Posterior Ventricular Puncture Sites Using a 3-Dimensional Brain Simulation Model  Voir?

To revalidate the craniometric dimensions of classic posterior burr holes for ventricular catheter insertion in hydrocephalic patients, based on ideal catheter position on a 3-dimensional simulated computed tomography (CT) reconstruction model of the ventricles.
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Delayed Intracerebral Hemorrhage Secondary to Ventriculoperitoneal Shunt: A Retrospective Study  Voir?

Postoperative delayed intracerebral hemorrhage (DICH) secondary to ventriculoperitoneal (VP) shunt is a rare but severe event. The present study aimed to investigate the incidence and risk factors related to DICH after placement of the VP shunt.
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Factors Determining the Outcome in Trigeminal Neuralgia Treated With Percutaneous Balloon Compression  Voir?

To analyze 3T magnetic resonance imaging (MRI) findings and clinical features of patients with trigeminal neuralgia (TN) who underwent percutaneous balloon compression and to determine whether these findings had an impact on prognosis of TN.
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Congenital Malformations of the Central Nervous System in Rural Western Honduras: A 6-Year Report on Trends  Voir?

Central nervous system (CNS) malformations, including neural tube defects (NTDs), are the second most common type of birth defects worldwide and are major causes of childhood disability and mortality. We report the first analysis of birth prevalence in Western Honduras of CNS malformations including NTDs over 6 consecutive years.

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Surgeries for Patients with Tandem Spinal Stenosis in Cervical and Thoracic Spine: Combined or Staged Surgeries?  Voir?

Cervical and thoracic tandem spinal stenosis (ct-TSS) is a rare yet challenging degenerative disease. When the diagnosis is made, surgical decompression is indicated for both lesions. However, literature about the surgical approaches and prognosis of this disease is lacking.
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AMD3100 Accelerates Reendothelialization of Neointima in Rabbit Saccular Aneurysm After Flow Diverter Treatment  Voir?

We sought to inspect the role of AMD3100, which acts as an antagonist of stromal cell–derived factor-1/CXC chemokine receptor 4 on the formation of neointima in rabbit saccular aneurysm after flow diverter (FD) treatment.
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Condylar Joint Fusion and Stabilization (by Screws and Plates) in Nontraumatic Atlanto-Occipital Dislocation: Technical Report of 2 Cases  Voir?

Nontraumatic spontaneous atlanto-occipital dislocation (AOD) is rare. In this report, we discuss the technical steps of condylar joint fusion and stabilization (by screws and plates) in nontraumatic AOD. To the best of our knowledge, it is the first report of such techniques.
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Takotsubo Cardiomyopathy Triggered by Venous Air Embolism During Craniotomy in the Sitting Position  Voir?

We present a case of stress-induced cardiomyopathy (Takotsubo cardiomyopathy) caused by a venous air embolism during a craniotomy performed in the sitting position.
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The Resolution of Oculomotor Nerve Palsy Caused by Unruptured Posterior Communicating Artery Aneurysms: A Cohort Study and Narrative Review  Voir?

Recovery of oculomotor nerve palsy after microsurgical and endovascular treatment has been studied in numerous small series of predominantly ruptured aneurysms. Little consideration has been given to the distinction between ruptured and unruptured aneurysms. This study examines the influence of treatment modality on oculomotor palsy recovery as a result of unruptured posterior communicating artery aneurysms.

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Recurrent Lumbar Disc Herniation After Tubular Microdiscectomy: Analysis of Learning Curve Progression  Voir?

Tubular microdiscectomy has become a staple technique among spine surgeons. Yet the associated learning curve, especially its later stages, has not been extensively studied. With studies reporting a higher rate of recurrent herniation using tubular microdiscectomy, surgeons' level of experience becomes of primary importance for the interpretation of such findings. We aimed to analyze possible improvements in the later stages of the learning curve and to identify factors independently associated with recurrent herniation.

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Passive Smoking Is Not Associated with Risk of Intracranial Aneurysm Rupture in Nonsmoking Women  Voir?

Active smoking is a major risk factor for intracranial aneurysm rupture (IAR); however, little is known about the effects of passive smoking on IAR. In China, female passive smoking is widespread and severe. This study aimed to assess whether passive smoking is associated with increased risk of IAR among nonsmoking women.

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Effect of Stereoscopic Anaglyphic 3-Dimensional Video Didactics on Learning Neuroanatomy  Voir?

The teaching of neuroanatomy in medical education has historically been based on didactic instruction, cadaveric dissections, and intraoperative experience for students. Multiple novel 3-dimensional (3D) modalities have recently emerged. Among these, stereoscopic anaglyphic video is easily accessible and affordable, however, its effects have not yet formally been investigated.

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Multicenter Retrospective Cohort Study of “Talk and Die” After Traumatic Brain Injury  Voir?

Patients who “talk and die” after traumatic brain injury (TBI) are potentially salvageable. The reported incidences and risk factors for the “talk and die” phenomenon are conflicting and do not take into account recent improvements in trauma care. The aim of this study was to determine the incidences of “talk and die” after TBI in a modern trauma care system, as well as associated risk factors.

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Subdural Hemorrhage from Cerebral Amyloid Angiopathy–Related Intracerebral Hemorrhage: A Risk Factor for Postoperative Hemorrhage  Voir?

Surgical treatment for cerebral amyloid angiopathy (CAA)–related intracerebral hemorrhage (ICH) is controversial. A subset of CAA-related ICH with associated subdural hemorrhage (SDH) has been reported. This study aimed to evaluate clinical results and surgical outcomes of this type of ICH with associated SDH.

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Incidence, Morbidity, and Surgical Outcomes of Complex Spinal Inflammatory Syndromes in Adults  Voir?

Spondylodiscitis is a rare inflammatory syndrome affecting intervertebral discs and adjacent vertebral bodies. Without appropriate therapy, serious complications, such as secondary spinal epidural abscess (SEA), may prolong recovery time. In this study, we compared the main characteristics of our cohort of patients with spondylodiscitis with those of patients reported in the international literature and analyzed the impact of complications associated with spondylodiscitis on clinical outcomes.

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Emerging Markers of Early Brain Injury and Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage  Voir?

Delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage is characterized by a highly complex pathophysiology and results in neurologic deterioration after the inciting bleed. Despite its significant consequences, prompt diagnosis can be elusive and treatment is often administered too late. Early brain injury, which occurs within the first 72 hours after ictus, may be an important factor for delayed cerebral ischemia and poor overall outcome. Here, we explore the purported clinical and pathologic manifestations of early brain injury to identify biomarkers that could have prognostic value.

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Use of Sodium Fluorescein in Meningioma Surgery Performed Under the YELLOW-560 nm Surgical Microscope Filter: Feasibility and Preliminary Results  Voir?

To evaluate the feasibility of sodium fluorescein (Na-Fl)–guided surgery involving the use of the PENTERO 900 surgical microscope equipped with the YELLOW-560 nm filter and low-dose Na-FL (200 mg/2–4 mg/kg) in meningioma surgery.
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Postoperative Radiculopathy Caused by a Retained Fractured Pedicle Cannulation Probe and Its Mechanism of Extraction  Voir?

Spine surgery relies heavily on technology and surgical instrumentation. Improperly used instrumentation can be detrimental to the patient. Despite multiple checkpoints to ensure that foreign bodies are not retained in surgery, numerous case reports have described retained foreign bodies; however, none of these cases involve retained instrumentation after open spine surgery. Of the retained objects, 4 were sponges and one was a Jamshidi needle fragment. Although smaller objects are more commonly the culprits, surgical instruments can break off, remain stuck, and cause clinical sequelae.

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Bevacizumab for Radiation Induced Optic Neuritis Among Aggressive Residual/Recurrent Suprasellar Tumors: More Than a Mere Antineoplastic Effect  Voir?

Angiogenesis and vascular endothelial growth factor (VEGF) have recently been implicated in animal and clinical models of radiation-induced optic nerve, retinal, and brain necrosis. Although there are isolated case reports of anti-VEGF therapy with bevacizumab for management of radiation-induced brain necrosis, there are little data defining its role in radiation-induced optic nerve damage.

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The Pathogenesis of Chronic Subdural Hematomas: A Study on the Formation of Chronic Subdural Hematomas and Analysis of Computed Tomography Findings  Voir?

The origin of chronic subdural hematomas (CSDH) and the pathophysiology of its enlargement remain unknown. The chemical fluid composition of CSDH, the contribution of cerebrospinal fluid (CSF) to its enlargement, and the relationship to its appearance on computed tomography (CT) also are not entirely clear.

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Probabilistic Tractography of the Cranial Nerves in Vestibular Schwannoma  Voir?

Multiple recent studies have reported on diffusion tensor-based fiber tracking of cranial nerves in vestibular schwannoma, with conflicting results as to the accuracy of the method and the occurrence of cochlear nerve depiction. Probabilistic nontensor-based tractography might offer advantages in terms of better extraction of directional information from the underlying data in cranial nerves, which are of subvoxel size.

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Histology-Stratified Tumor Control and Patient Survival After Stereotactic Radiosurgery for Pineal Region Tumors: A Report From the International Gamma Knife Research Foundation  Voir?

Pineal region tumors represent a rare and histologically diverse group of lesions. Few studies are available to guide management and the outcomes after stereotactic radiosurgery (SRS).
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Lumbosacral Transitional Vertebra: Possible Role in the Pathogenesis of Adolescent Lumbar Disc Herniation  Voir?

To investigate the role of lumbosacral transitional vertebra (LSTV) in the pathogenesis of adolescent lumbar disc herniation (ALDH) and the association between LSTV type and the herniation level of ALDH.
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Identification of Driver Genes and Key Pathways of Pediatric Brain Tumors and Comparison of Molecular Pathogenesis Based on Pathologic Types  Voir?

This study is to identify pediatric brain tumors (PBT) driver genes and key pathways to detect the expression of the driver genes and also to clarify the relationship between patients' prognosis and expression of driver genes.
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Impact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients  Voir?

There is a paucity of data determining the impact that gender disparities have on spine outcomes, particularly perception of health and satisfaction. The aim of this study was to determine whether there is a difference in 3-month and 1-year patient-reported outcomes and satisfaction after elective lumbar spine surgery.

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Novel Use of the Leksell Gamma Frame for Stereotactic Biopsy of Posterior Fossa Lesions  Voir?

Stereotactic transcerebellar biopsies of brainstem tumors have often been reported. The Leksell frame or Cosman-Roberts-Wells frame is often used in transcerebellar approaches. However, to access lesions via the cerebellum, these frames should be secured as inferiorly on the cranium as possible, which can require exaggerated neck flexion and limit the flexible trajectory to the target. To overcome these disadvantages, we have devised a new way to use the Leksell frame for transcerebellar approaches.

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Preoperative Frailty Score for 30-Day Morbidity and Mortality After Cranial Neurosurgery  Voir?

Evaluating preoperative frailty is critical for guiding shared surgical decision-making. The purpose of this study was to develop a novel preoperative frailty index for classification of adverse outcomes following cranial neurosurgery procedures.
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Incidence, Demographics, and Outcome of Traumatic Brain Injury in The Middle East: A Systematic Review  Voir?

Traumatic brain injury (TBI) is a serious global public health challenge. We aimed to assess the pattern of TBI in the Middle East, as reported in the last decade.
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Endoscope-Assisted Abscess Drainage Secondary to Endoscope-Assisted Transforaminal Lumbar Interbody Fusion: 1-Year Follow-Up  Voir?

Endoscopic discectomy and fusions have been gaining popularity in the recent past and are noted to be safe for their application in elderly population. The procedure involves ultra-small incision for discectomy followed by placement of percutaneous screws in awake patients. Treatment of advanced spinal pathology with endoscope-assisted techniques is challenging. Although not common with the endoscopic approach, postoperative infection can be problematic, as there are no established guidelines on its management.

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Bifurcation Location and Growth of Aneurysm Size Are Significantly Associated with an Irregular Shape of Unruptured Intracranial Aneurysms  Voir?

Previous studies firmly proved that an irregular aneurysmal shape was associated strongly with intracranial aneurysm (IA) rupture, but it is unclear how irregularly shaped IAs form. We aimed to identify the factors related to irregular shape of IAs.
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Survival Patterns of 5750 Stereotactic Radiosurgery–Treated Patients with Brain Metastasis as a Function of the Number of Lesions  Voir?

The number of brain metastases (BMs) plays an important role in the decision between stereotactic radiosurgery (SRS) and whole-brain radiation therapy.
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Isolated Subcallosal Artery Infarction Secondary to Localized Cerebral Vasospasm of Anterior Communicating Artery Complex Following Subarachnoid Hemorrhage  Voir?

Subcallosal artery (ScA) infarction is a well-recognized but uncommon complication of surgical treatment of anterior communicating artery aneurysms.
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Kinase Activity in Recurring Primary Skull Base Chordomas and Chondrosarcomas: Identification of Novel Pathways of Oncogenesis and Potential Drug Targets  Voir?

Chordomas and chondrosarcomas can occur in the skull base. Currently, 45% of chordomas and 56% of chondrosarcomas recur within 5 years of surgery. The role of adjuvant therapy is highly debated. No pharmacotherapies have been approved by the U.S. Food and Drug Administration for chordomas or chondrosarcomas. High propensity for recurrence and lack of definitive adjuvant therapy necessitate additional basic science research to identify molecular anomalies associated with recurrent disease.

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Microsurgical Bypass Training Rat Model, Part 1: Technical Nuances of Exposure of the Aorta and Iliac Arteries  Voir?

Animal models using rodents are frequently used for practicing microvascular anastomosis—an essential technique in cerebrovascular surgery. However, safely and efficiently exposing rat's target vessels is technically difficult. Such difficulty may lead to excessive hemorrhage and shorten animal survival. This limits the ability to perform multiple anastomoses on a single animal and may increase the overall training time and costs. We report our model for microsurgical bypass training in rodents in 2 consecutive articles.

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Can We Make Simple In Situ Decompression of the Ulnar Nerve at the Elbow Still Easier?  Voir?

In situ decompression and transposition are equally effective in cubital tunnel syndrome treatment. Both are traditionally performed in the supine position.
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Spinal Arteriovenous Malformation Associated with Parkes Weber Syndrome: Report of Two Cases and Literature Review  Voir?

To present 2 cases of Parkes Weber syndrome (PWS) with spinal arteriovenous malformation (AVM) and discuss the radiologic features and clinical treatment with literature review.
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Protective Functions of PJ34, a Poly(ADP-ribose) Polymerase Inhibitor, Are Related to Down-Regulation of Calpain and Nuclear Factor-κB in a Mouse Model of Traumatic Brain Injury  Voir?

Poly(ADP-ribose) polymerase (PARP), calpain, and nuclear factor-κB (NF-κB) are reported to participate in inflammatory reactions in pathologic conditions and are involved in traumatic brain injury. The objective of this study was to investigate whether PARP participates in inflammation related to calpain and NF-κB in a mouse model of controlled cortical impact (CCI).

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Microsurgical Bypass Training Rat Model: Part 2–Anastomosis Configurations  Voir?

Mastery of microsurgical anastomosis is key to achieving good outcomes in cerebrovascular bypass procedures. Animal models (especially rodents) provide an optimal preclinical bypass training platform. However, the existing models for practicing different anastomosis configurations have several limitations.

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Cranium Bifidum Occultum Associated with Hypertelorism Treated with Posterior Vault Reconstruction and Orbital Box Osteotomies: Case Report and Technical Note  Voir?

Cranium bifidum occultum is a disorder of skull ossification presenting as an enlarged posterior fontanelle in the upper posterior angle of the parietal bone near the intersection of the sagittal and lambdoid sutures. The standard treatment for cranium bifidum occultum is observation. We present a case of a 5-year-old boy who presented with a 15 × 4.5 cm midline posterior cranial vault defect consistent with diagnosis of cranium bifidum occultum associated with orbital hypertelorism and a widened nose.

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Endovascular Treatment of Complex Distal Posterior Cerebral Artery Aneurysms with the Pipeline Embolization Device  Voir?

To assess the safety and efficacy of the Pipeline Embolization Device (PED) for endovascular treatment of complex, distal posterior cerebral artery (PCA) aneurysms.
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Micro-Multileaf Collimator LINAC Radiosurgery for Vestibular Schwannomas  Voir?

This study evaluates the efficacy of linear accelerator (LINAC) radiosurgery using micro multi-leaf collimator technique (μMLC) in the treatment of a consecutive series of patients with vestibular schwannomas.
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WITHDRAWN: The modified impact factor; a letter to the editor  Voir?

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
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WITHDRAWN: Outcomes After Anterior Lumbar Interbody Fusion Versus Transforaminal Lumbar Interbody Fusion for the Treatment of Symptomatic L5–S1 Spondylolisthesis: A Prospective, Multi-Institutional Comparative Effectiveness Study  Voir?

Available online 25 September 2015
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WITHDRAWN: Refining the Role for Evacuation of Spontaneous Intracerebral Hematomas: Results of STICH II  Voir?

The Publisher regrets that this article is an accidental duplication of an article that has already been published, DOI of original article: http://dx.doi.org/10.1016/j.wneu.2014.08.046. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

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Upcoming Events  Voir?

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Editor's Choices  Voir?

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Subscription Information  Voir?

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Editorial Board  Voir?

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Contents  Voir?

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WORLD NEUROSURGERY's Mission Statement  Voir?

We at WORLD NEUROSURGERY have felt, for some time, that it was time to revisit our mission statement. In the July issue of WORLD NEUROSURGERY, my Editor-in-Chief letter addressed the original mission statement. I provided a “rough draft” modification of the first and only rendition of the statement and asked for advice from the readership. The original mission statement is provided here as a reference:

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In Reply to the Letter to the Editor “Imaging Classification and Treatment of Spontaneous Intracranial Fusiform and Dissecting Aneurysms”  Voir?

Dear Editor-in-Chief,
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Imaging Classification and Treatment of Spontaneous Intracranial Fusiform and Dissecting Aneurysms  Voir?

We read with great interest the article by Zhang et al.1 titled “Endovascular Treatment of Spontaneous Intracranial Fusiform and Dissecting Aneurysms: Outcomes Related to Imaging Classification of 309 Cases.” We appreciate the authors' attempt to try to classify an unusual and diverse (rather black spot) pathology, i.e., various forms of dilations of intracranial artery segments, in a single setting. Unlike Zhang et al., we do not include intracranial artery wall dissections within the category of intracranial aneurysms.

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Letter to the Editor Regarding “The Extended Lateral Supraorbital Approach and Extradural Anterior Clinoidectomy Through a Frontopterio-Orbital Window: Technical Note and Pilot Surgical Series”  Voir?

Andrade-Barazarte et al.1 present a well-written report about an improvement of the lateral supraorbital (LSO) approach of Hernesniemi by combining it with the extradural anterior clinoidectomy popularized by Dolenc named the extended LSO approach. One of the most important limitations of the LSO approach are the lesions located in the skull base, which is why the extended LSO approach was developed by the authors. The approach presented by Andrade-Barazarte et al.1 is an attempt to partially resolve the problem of lesions with skull base extension.

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Letter to the Editor Regarding “Extent of T1+C Intensity Is a Predictor of Blood Loss in Resection of Meningioma”  Voir?

We read with great interest the article by Nguyen et al.1 They concluded that along with gender and tumor volume, extent of T1+C intensity is also an independent predictor of estimated blood loss in meningioma surgery. We commend the authors for performing this study on a topic that is clinically very much relevant. However, we would like to bring a few facts to the attention of the readers.

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Letter to the Editor Regarding “Burr-Hole Drainage for Chronic Subdural Hematoma under Low-Dose Acetylsalicylic Acid: a Comparative Risk Analysis Study”  Voir?

This is in reference to the article “Burr-Hole Drainage for Chronic Subdural Hematoma Under Low-Dose Acetylsalicylic Acid: A Comparative Risk Analysis Study” by Kamenova et al.1 The authors compared the perioperative and postoperative bleeding and cardiovascular complication rates of patients undergoing burr-hole drainage for chronic subdural hematoma with and without discontinuation of low-dose acetylsalicylic acid (ASA). We would like to point out a few limitations of the study that we found on reading the article.

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Meningocele and Meningoencephalocele of the Lateral Wall of Sphenoidal Sinus  Voir?

We thank Basant Kumar Misra and Milind V. Kirtane for their commentary1 on our article entitled “Meningocele and meningoencephalocele of the lateral wall of sphenoidal sinus: the role of the endoscopic endonasal surgery.”2
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Dernière mise à jour : 16/10/2017 : 17:44


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