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Sommaires des Revues - Word Neurosurgery

World Neurosurgery

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Ventro-lateral motor thalamus abnormal connectivity in essential tremor before and after thalamotomy: a resting-state fMRI study  Voir?

To evaluate functional connectivity (FC) of the ventro-lateral thalamus, a common target for drug-resistant essential tremor (ET), resting-state data were analyzed before and 1 year after stereotactic radiosurgical thalamotomy (SRS-T), and compared against healthy controls (HC).
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DEFUSE - 3: Reinforcing evidence for extended endovascular intervention time window for ischemic stroke  Voir?

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Understanding the Functional Neuroanatomical basis of Meditation for Improving Patient Wellness and Outcomes  Voir?

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The influence of artificial cervical disc prosthesis height on the cervical biomechanics: a finite element study  Voir?

Artificial cervical disc replacement is expected to maintain normal cervical biomechanics. The effect of Prestige LP prosthesis height on cervical biomechanics has not been thoroughly studied yet. This finite element (FE) study of the cervical biomechanics aims to predict how the parameters like range of motion (ROM), adjacent intradiscal pressure, facet joint force and bone-implant interface stress are affected by different Prestige LP prosthesis heights.

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Use of a pediatric craniotome drill for cervical and thoracic spine decompression: Safety and efficacy  Voir?

Laminectomy utilizing a high-speed drill with an unprotected cutting drill bit can be rapid and effective, but it has been associated with known complications. Another technique utilizes a pediatric craniotome drill with the footplate attachment. Currently, there are no studies comparing clinical outcomes between these two stated decompressive techniques.

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Divergent bilateral PLIF with cortical screw fixation: Description of new trajectory for interbody technique from midline exposure  Voir?

A major drawback to the use of cortical bone trajectory pedicle screws (CBTPS) with traditional posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) grafts is that traditional graft insertion trajectories require a wider posterior exposure. This wider exposure, beyond the limits otherwise required for CBTPS placement, negates a primary benefit of CBTPS fixation.

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The effects of intermittent whole-body hypoxic preconditioning on patients with carotid artery stenosis  Voir?

To study the effects of intermittent whole-body hypoxic preconditioning on patients with carotid artery stenosis.
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Anatomical Variations of Brain Venous Sinuses in Patients with Arteriovenous Malformations: Incidental Finding or Causative Factor?  Voir?

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Characteristics and endovascular management of the posterior cerebral artery anterior temporal branch aneurysms  Voir?

To investigate characteristics of the posterior cerebral artery anterior temporal branch (ATB) aneurysm and the safety and efficacy of endovascular management.
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Biomechanical stability afforded by unilateral vs. bilateral pedicle screw fixation with and without interbody support using lateral lumbar interbody fusion  Voir?

To determine the stability of fusion constructs with unilateral pedicle screw (UPS) or bilateral pedicle screw (BPS) fixation with and without an interbody implant using the lateral lumbar interbody (LLIF) approach.
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Another Endovascular Therapy Strategy for Acute Tandem Occlusion: Protect-Expand-Aspiration-Revascularization-Stent (PEARS) Technique  Voir?

Initial stenotic occlusion of the internal carotid artery (ICA) with intracranial artery occlusion in acute ischemic stroke is associated with high morbidity and can benefit from endovascular therapy. However, the optimal endovascular strategy is unclear. This study aimed to evaluate the feasibility of the “half” anterograde approach and clinical outcome of treated patients. Revascularization validity of the two “half” anterograde approach with (PEARS technique) or without (plain technique) using an embolic prevention device and aspiration was also compared.

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Tiny cerebral aneurysms can be safely and effectively treated with LVIS stent-assisted coiling or coiling alone  Voir?

The effect and safety of LVIS stent-coiling is currently not known for treating tiny intracranial aneurysms.
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Age-Dependent Attitudes of Ischemic Patients towards Disability after Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Infarction  Voir?

To improve the process of surgical informed consent, patient attitudes towards acceptable levels of disability after decompressive surgery for malignant middle cerebral artery infarction are investigated, including the impact of patient age.
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A case of subarachnoid hemorrhage from ruptured oncotic fusiform aneurysms from choriocarcinoma metastasis treated with aneurysmectomy and vessel reconstruction  Voir?

Oncotic aneurysm is a rare condition with a high mortality rate. Since no consensus has been reached regarding therapeutic strategy for ruptured oncotic aneurysm, treatment remains challenging.
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Exophytic cerebral hemispheric low grade glioma: An unusual growth pattern of a common central nervous system tumour  Voir?

Exophytic growth (EG), where in the tumor mass grows beyond the neuraxial boundary formed by pia mater, remains a rare pattern of glioma growth. It has been described in gliomas at several locations like the brainstem, cerebellum, suprasellar area, spinal cord and the insula. However, EG in hemispheric grade 2 astrocytomas, particularly affecting the convexity subarachnoid space, as against the more spacious basal subarachnoid space, is exceedingly rare. To the best of our knowledge, there is only one such case reported in the English literature.

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Clinical features and surgical management of cerebellopontine angle cholesteatoma presented as trigeminal neuralgia  Voir?

It is difficult to differentiate patients with cerebellopontine angle (CPA) cholesteatoma and patients with primary trigeminal neuralgia(TN) just according to early symptoms. We aimed to explore the clinical characteristics, early diagnosis and microneurosurgical techniques for CPA cholesteatoma presented as trigeminal neuralgia.

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Preoperative 3-dimensional angiography data and intraoperative real-time vascular data integrated in microscope-based navigation by automatic patient registration applying intraoperative computed tomography  Voir?

To establish a workflow integrating preoperative 3-D angiography data, as well as intraoperative real-time vascular information in microscope-based navigation for aneurysm and arteriovenous malformation surgery.Patients & Methods: In 7 patients (3 arteriovenous malformations, 4 aneurysms) preoperative 3-D rotational angiography or computed tomography (CT) or magnetic resonance angiography data were navigated applying a 32-slice movable CT scanner for low-dose registration scanning. 3-D vasculature was segmented and visualized by microscope-based navigation along with navigated intraoperative real-time imaging data from indocyanin green angiography and duplex ultrasonography.

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Neurosurgery on a pregnant woman with post-mortem fetal extrusion: an unusual case from Medieval Italy  Voir?

Trepanation is one of the most ancient and applied surgical treatments; several archaeologically documented cases are known, dated back from Prehistory to the Middle ages.This case study reports the anthropological analysis of the skeletal remains of a young medieval woman and a fetus (Imola, Italy). The fetal remains were laid between her pelvis and lower limbs. A perforating injury was observed to her frontal bone. After assessing biological profiles, we attempted to interpret the injury and to reconstruct possible circumstances of death.The lesion seems commensurate with a surgical intervention; signs of an osteogenic reaction were detected at its edges.

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Anatomical study of the nutrient foramina of the posterior axis with application to C2 pedicle screw placement  Voir?

Pedicle screws placed into C2 necessitate a thorough understanding of this bone’s unique anatomy. Although multiple landmarks and measurements have been used by surgeons, these are often varied in the literature with no consensus. Herein, we studied one recently proposed landmark using the nutrient foramina of the posterior aspect of C2 for pedicle screw placement.

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Brainstem dose constraints in non-isometric radiosurgical treatment planning of trigeminal neuralgia: a single-institution experience  Voir?

CyberKnife stereotactic radiosurgery (SRS) for trigeminal neuralgia (TGN) administers non-isometric, conformational high-dose radiation to the trigeminal nerve with risk of subsequent hypoesthesia.
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Cardiac Metastasis from Clivus Chordoma: A Case Report  Voir?

Chordomas are rare tumors showing locally aggressive nature and high rates of local recurrences. Distant metastases are infrequently reported and cardiac metastases are extremely rare.
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The factors affecting the difficulty of percutaneous cylindrical electrode placement for spinal cord stimulation  Voir?

Optimal placement of electrodes is important for spinal cord stimulation. Unfortunately, factors affecting the difficulty of percutaneous electrode placement are not well known. In this study, we retrospectively evaluated the factors affecting the difficulty of percutaneous electrode placement.
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Iatrogenic Spondylolisthesis Following Open Lumbar Laminectomy: Case Series and Review of the Literature  Voir?

The diagnosis and surgical management of post-laminectomy spondylolisthesis in patients without pre-operative instability is presented with a review of relevant literature.
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Management of Skull Base Tumors in the Obstetric Population: a Case Series  Voir?

Neoplasms rarely present during pregnancy. However, increase in plasma volume, hormone release induced growth, and tumor hypervascularity, can cause rapid symptoms. These range from not requiring intervention to necessitating emergent operations. Objective: We describe an algorithm for the management of symptomatic neoplasm in the obstetric population, and provide recommendations regarding surgical indications and timing.

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Rope Jumping-induced Traumatic Compression Fractures: The Underestimated Danger of Repetitive Axial Load Forces  Voir?

The author describes a case of a non-osteoporotic adult presenting with multilevel compression fractures at the apex of the thoracic kyphosis after strenuous rope jumping. MRI demonstrated diffuse bone marrow changes in the vertebral bodies with only a very small unilateral endplate fracture. Besides highlighting the oftentimes neglected role of repetitive sub-pathological axial load forces in traumatic spinal injuries, the observed imaging pattern substantiates previous experimental studies which demonstrated that under cyclic axial loading the initial damage occurs in the cancellous regions of the bone (with observation of microscopic/50-100 μM long cracks), ultimately leading to a reduction in its elastic modulus.

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Abscess within a glioblastoma: mimicking a matryoshka doll  Voir?

Abscess co-existing within a brain tumor is a rare entity. Case reports in literature primarily consist of sellar pathology and parenchymal lesions including meningioma, glioma, and metastases. We report a case of glioblastoma with an intra-tumoral abscess in a middle-aged lady with no prior invasive procedure or systemic focus of infection.

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Delayed post-traumatic subacute lumbar subarachnoid hematoma: Case report and review of the literature  Voir?

Traumatic spinal subarachnoid hematoma, associated or not to a concurrent subdural hematoma has rarely been described. The evolution of such hematomas is heterogeneous. This study aims at defining the most accurate management which is currently not standardized.
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Self-Reported Headaches in Patients with Unruptured Intracranial Aneurysms Treated with the Pipeline Embolization Device  Voir?

The objective of this study was to analyze patients’ perceptions of their headaches both prior to and following Pipeline flow diversion treatment of their unruptured intracranial aneurysms, with the goal of identifying prognostic factors associated with headache patterns to improve predictions of overall outcomes.

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Traumatic spinal injury: global epidemiology and worldwide volume  Voir?

Traumatic spinal injury (TSI) results from injury to bony, ligamentous and/or neurological structures of the spinal column and can cause significant morbidity and mortality. The global burden of TSI is poorly understood, so we performed a systematic review and meta-analysis to estimate the global volume of TSI.

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Optic Nerve Atrophy Due To Long-Standing Compression By Planum Sphenoidale Meningioma  Voir?

In this study we report an uncommon endoscopic endonasal image of an atrophic optic nerve as seen after surgical removal of a suprasellar meningioma. The peculiarity of this case is the long-lasting underestimated ocular symptomatology of the patient who reported a 15-year history of impairment of vision on her left eye. After making serendipitously the diagnosis of a suprasellar mass, an endoscopic endonasal surgery was performed and, at the end of tumor removal, the impressive left optic nerve atrophy due to enduring local compression was visualized.

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Cyst With a Twist!: a Diagnostic Dilemma  Voir?

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The differentially expressed genes of Human Sporadic Cerebral Cavernous Malformations  Voir?

To understand the development of Sporadic cerebral cavernous malformations (SCCM) comprehensively, we analyzed gene expression profiles in SCCMs by the gene microarray.
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Complications of impulse generator exchange surgery for deep brain stimulation: A single-centre, retrospective study  Voir?

Non-rechargeable deep brain stimulation (DBS) impulse generators (IG) with a low or empty battery status require surgical IG exchange several years after initial implantation. Complication rates in patients undergoing DBS surgery range from 7.6% to 25.3%. The aim of this study was to investigate the complication rates after IG exchange surgery and to identify risk factors for complications.

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A frontal sinus osteoma accompanied by an intracranial mucocele and local hyperostosis frontalis interna  Voir?

Frontal sinus osteoma accompanied by intracranial mucocele and local hyperostosis frontalis interna has never been reported. A 47-year-old woman presented with a 3-month history of intermittent headache. Physical examination revealed no neurological abnormality. Contrasted MRI showed a frontal heterogeneously enhanced lesion with adjacent non-enhanced cyst. Computed tomography showed a bone-density mass, which was accompanied by local hyperostosis frontalis interna, filled the left frontal sinus and extended intracranially.

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Microsurgical clipping of intracranial aneurysms assisted by neurophysiological monitoring, microvascular flow probe and ICG-VA. Outcomes and intraoperative data on a multimodal strategy  Voir?

The aim of this study is to report data on a multimodal monitoring strategy based on the intraoperative use of neurophysiological monitoring, flowmetry by microflow probe and intraoperative indocyanine green-videoangiography (ICG-VA) during microsurgical clipping of intracranial aneurysms.
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Hypoplastic straight sinus with persistent falcine sinus in an adult with sinus pericranii  Voir?

Open MRI of a 45-year-old man with panic disorder showed a sinus pericranii (SP). Examination of the scalp revealed a discolored scalp mass and MR venography displayed a hypoplastic straight sinus with persistent falcine sinus.SP is a venous anomaly consisting of a transosseous vascular channel connecting an intracranial sinus with subgaleal veins. High venous pressure in the late embryonic stage, as with a hypoplastic straight sinus, has been hypothesized to predispose affected individuals to develop other venous anomalies, i.e.

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The Risk of Traumatic Brain Injury Occurring among Patients with Parkinson’sDisease: A 14-Year Population-Based Study  Voir?

Previous studies have implicated traumatic brain injury (TBI) as a risk factor for Parkinson’s disease (PD). However, the incidence risk of new-onset TBI among patients with PD is not well established. This study investigated the contribution of PD to new-onset TBI associations.
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“White Cord Syndrome” of Acute Hemiparesis after Posterior Cervical Decompression and Fusion for Chronic Cervical Stenosis  Voir?

“White cord syndrome” is a very rare condition thought to be the result of acute reperfusion of chronically ischemic areas of the spinal cord. Its hallmark is the presence of intramedullary hyperintense signal on T2-weighted MRI sequences in a patient with unexplained neurologic deficits following a spinal cord decompression. The syndrome is rare and has been reported previously in two patients following anterior cervical decompression and fusion.

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End-Stage Liver Disease in Patients with Intracranial Hemorrhage is associated with Increased Mortality: A Cohort Study  Voir?

End-stage liver disease (ESLD) is a devastating consequence of hepatocyte destruction that is associated with intracranial hemorrhage (ICH).
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Burr hole surgery for chronic subdural hematoma with extensive scalp burn: a case report  Voir?

Neurosurgical intervention for a patient with an extensive scalp burn is rare, but it might be associated with the high risk of surgical site infection.
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Movement Disorders and Deep Brain Stimulation in the Middle East  Voir?

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Effect and feasibility of endoscopic surgery in the spontaneous intracerebral hemorrhage: a systematic review and meta-analysis  Voir?

The spontaneous intracerebral hemorrhage remains a major cause for death and dependence. Endoscopic surgery (ES) is potential to improve outcomes, but the consensus on the superiority of ES is not achieved. We conducted a systematic review to clarify the effect ES in sICH and compare it with other treatment options (craniotomy, conservation and stereotactic aspiration [SA]).

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Louis Victor Leborgne (“Tan”)  Voir?

Louis Victor Leborgne was a patient of Paul Broca. “Monsieur Leborgne” as Paul Broca would call him was also known around in the hospital by the nickname, “Tan,” His neurological condition left him with a difficulty in speaking and he could only speak the word “Tan”. Leborgne spent nearly half of his entire life in the hospital. He was initially admitted into the psychiatry division of the hospital and was later transferred under the care of Broca towards the end of his life. The story of the Leborgne sits in the crossroads of human thoughts that led to the discovery of cerebral localization.

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Treatment of a wide-neck bifurcation aneurysm using a “WEB device waffle-cone technique”. Technical note and case report.  Voir?

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Awake Microvascular Decompression for Trigeminal Neuralgia: Concept and Initial Results  Voir?

The option of performing MVD under awake anesthesia protocol (“awake” MVD) was examined in this initial series to assess whether intraoperative pain evaluation can identify and mitigate insufficient decompression of the trigeminal nerve, improving surgical outcomes. Additionally, “awake” MVD could expand procedure indications for those with comorbidities that would prohibit general endotracheal anesthesia (GEA).

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Bone Metabolic Markers in the Clinical Assessment of Patients with Superior Semicircular Canal Dehiscence Treated with Middle Fossa Craniotomy  Voir?

Superior semicircular canal dehiscence (SSCD) is a bony defect in the osseous shell of the petrous temporal bone. The pathophysiological association between osteoporosis and SSCD remains poorly understood. We aim to investigate the relationships between serum calcium, 25-hydroxyvitamin D, and thyroid stimulating hormone levels, and symptoms in adult patients with SSCD treated through a middle fossa craniotomy.

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The minimally invasive alternative approaches to the pterional craniotomy: A systematic review of the literature  Voir?

Minimally invasive alternatives to the pterional craniotomy include the minipterional and the supraorbital craniotomy (SOC). The latter is performed via either an eyebrow or an eyelid skin incision. The purpose of this systematic review was to analyze the type and the incidence of approach-related complications of these keyhole craniotomies.

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Endoscopic Neurosurgery: Surgeon vs Machine  Voir?

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Technical Aspects of Awake Craniotomy With Mapping for Brain Tumors in a Limited Resource Setting  Voir?

Brain tumor surgery near or within eloquent regions is increasingly common and is associated with a high risk of neurological injury. Awake craniotomy with mapping has been shown to be a valid method to preserve neurological function while increasing the extent of resection. However, the technique used varies greatly among centers. Most count on professionals such as neuropsychologists, speech therapists, neurophysiologists or neurologists to help in intraoperative patient evaluation. We describe our technique with the sole participation of neurosurgeons and anesthesiologists.

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Atypical teratoid/rhabdoid tumor after in-vitro fertilization: illustrative case report and systematic literature review  Voir?

In vitro fertilization (IVF) is increasingly used for treatment of infertile couples worldwide. The association between IVF and cancer risk in offsprings is conflicting. We present a case of atypical teratoid/rhabdoid tumor (AT/RT) in a girl conceived by IVF and present results of systematic review of literature of primary intracranial neoplasms diagnosed in children conceived by IVF.

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Does the iliac wing influence L5 pedicle screw fixation?  Voir?

To explore whether the iliac wing influenced L5 PS fixation and to propose methods to reduce such influence.
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Necessity of Repeat CT Imaging in Isolated Mild Traumatic Subarachnoid Hemorrhage  Voir?

The standard of care for isolated mild traumatic subarachnoid hemorrhage (itSAH) involves serial head CT examinations at dedicated time-intervals to monitor neurologic status and hemorrhagic progression. Considering recent evidence questioning such an aggressive monitoring protocol, this study aimed to assess the necessity of repeat head CT imaging in managing itSAH.

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S2AI screw insertion: technical note with pictorial guide  Voir?

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Cerebellar Peduncle Localized Oligodendroglioma: A Case Report and Review of the Literature  Voir?

Oligodendrogliomas constitute 5% of all primary brain tumors and are the third most common cancer among intracranial tumors. More than 90% of oligodendrogliomas have supratentorial localization. Oligodendrogliomas arising in cerebellar peduncle are substantially rare even less than 1%. Up to now, six oligodendroglioma cases with cerebellar peduncle localization have been presented. We aimed to discuss our WHO grade II oligodendroglioma case which originated from cerebellar peduncle in the light of literature.

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Sphenoid mucocele with intracranial extension: An anatomical perspective  Voir?

Isolated sphenoid mucoceles are rare, but due to their close proximity to important vasculonervous structures, local extension may result in serious consequences.
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'Suspended Posterior tubercle of atlas' with atlanto-axial dislocation  Voir?

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Cervical Spinal Fusion: 16-Year Trends in Epidemiology, Indications, and In-hospital Outcomes by Surgical Approach  Voir?

The rate of cervical spinal fusion has been increasing significantly. However, there is paucity of literature describing trends based on surgical approach using complete population databases. We investigated the approach-based trends in epidemiology, indications and in-hospital outcomes of cervical spinal fusion.

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Transvertebral bone graft and augmentation versus posterior spinal instrumentation in the treatment of simple thoracolumbar compression fractures  Voir?

This retrospective cohort study was performed to investigate clinical efficacy of TBGA in comparison to the pedicle screw fixation(PSF).
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The First Neurosurgery Boot Camp in Southeast Asia: Evaluating impact on knowledge and regional collaboration in Yangon, Myanmar  Voir?

For the first time in Southeast Asia, a Fundamentals of Neurosurgery Boot Camp was held at the University of Medicine 1 in Yangon, Myanmar, February 24-26, 2017. The aim of this course was to teach and train fundamental skills to neurosurgery residents.
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Improving sperm viability after spinal cord injury using hyperbaric therapy  Voir?

Infertility is one of many complications of spinal cord injury (SCI) in male patients who are often at the peak of their reproductive life. This study evaluated the effects of hyperbaric therapy (HT) on the quality of sperm of rats submitted to SCI, correlating the findings with a histological analysis of the testicles.

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Utility of 3D printed models in enhancing the learning curve of surgery of tuberculum sellae meningioma  Voir?

To investigate the value of 3D printed models with pathological entities in enhancing the learning curve of surgery of tuberculum sellae meningioma.
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Expression of MMP-9, PTTG, HMGA2, and Ki-67 in ACTH-secreting pituitary tumors and their association with tumor recurrence  Voir?

MMP-9, PTTG, and HMGA2 play important roles in the tumorigenesis of adrenocorticotrophic hormone (ACTH)-secreting pituitary tumors, but their associations with tumor recurrence after transsphenoidal adenomectomy remain unclear. The aim of the study was to investigate the immunohistochemical expression profiles of MMP-9, PTTG, HMGA2, and Ki-67 in recurrent and non-recurrent ACTH-secreting pituitary tumors and to identify their associations with tumor behavior and recurrence status.

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Functional-based resection does not worsen quality of life in patients harboring a diffuse low-grade glioma involving eloquent brain regions: a prospective cohort study  Voir?

We assessed the impact of surgery on postoperative cognitive function and ability to work in adult patients harboring a diffuse low-grade glioma involving eloquent brain regions and having a functional-based maximal surgical resection using intraoperative corticosubcortical mapping under awake conditions.

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Postoperative cerebral infarction risk factors and postoperative management of pediatric moyamoya disease patients  Voir?

Though revascularization surgery for moyamoya disease patients can effectively prevent ischemic events and thus improve the long-term clinical outcome, the incidence of postoperative ischemic complications affects patients’ quality of life. This study aimed to clarify the risk factors associated with postoperative ischemic complications and to discuss the appropriate perioperative management.

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Prognostic factors of surgical complications and overall survival of patients with metastatic spinal tumor  Voir?

Achievements of oncological treatments increase the incidence of spinal metastases. The surgical treatment of spinal metastases results in a high complication rate which must set against the expected benefits. The aim of this article is to summarize an extended database of patients with spinal metastases and to study the effect of several prognostic factors on surgical complications and survival time.

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National Trends for Reoperation in Elderly Patients with Glioblastoma  Voir?

Despite multimodal therapies extending patient survival, Glioblastoma (GBM) recurrence is all but a certainty. To date, there are few single-center studies looking at reoperations. Our study aimed to assess GBM reoperation trends nationally in elderly patients, with emphasis on outcomes.
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Digital Footprint of Neurological Surgeons  Voir?

Patients are increasingly turning to online resources to inquire about individual physicians and to gather health information. However, little research exists studying the online presence of neurosurgeons across the country. This study aims to characterize these online profiles and assess the scope of neurosurgeons' digital identities.

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Management and survival of adult patients with pilocytic astrocytoma in the National Cancer Database  Voir?

Adult pilocytic astrocytomas (PA) are relatively rare central nervous system (CNS) tumors with a favorable prognosis. We sought to investigate existing clinical management strategies and overall survival (OS) as a function of various clinical characteristics among adult patients with PA.
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Traumatic Lateral spondyloptosis: case series  Voir?

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Life After the Neurosurgical Ward in SubSaharan Africa: Neurosurgical Treatment and Outpatient Outcomes in Uganda  Voir?

In the past decade, neurosurgery in Uganda experienced increasing surgical volume and a new residency training program. While research has examined surgical capacity, minimal data exists on the patient population treated by neurosurgery and their eventual outcomes in sub-Saharan Africa.
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Primary intracranial angioleiomyomas as rare, nonmalignant, and distinct neoplastic entities: a series of 8 cases and a literature review  Voir?

Primary intracranial angioleiomyoma is a rare and distinct neoplasm. Only 29 cases have been reported previously, and we aimed to investigate the clinical and radio-pathological features of these lesions.
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Is edema a matter of concern, after laser ablation of epileptogenic focus?  Voir?

A stereotactically placed laser fiber can deliver thermal energy to an epileptogenic focus in brain. This procedure is done under intraoperative (thermography) magnetic resonance imaging (MRI) guidance. Thermoablation can lead to edema in surrounding area and can cause secondary insult. In this case report of three cases, we have quantified the edema produced after laser ablation, with sequential MRI in immediate post-operative period.

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Intraventricular epithelioid glioblastoma: A case report  Voir?

Epithelioid glioblastoma, a high-grade, diffuse astrocytic tumor variant, comprises closely packed epithelioid cells and rhabdoid cells. This rare tumor usually develops in the cerebral cortex and diencephalon; however, in one woman, it was located intraventricularly.
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Spontaneous cervical spinal epidural hematoma associated with Dabigatran: a case report  Voir?

While spontaneous spinal epidural hematomas are rare, one of the identified risk factors is vitamin K antagonist therapy.
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Defining a Clopidogrel Response Cut-Off Value Using Light Transmission Aggregometry Prior to Pipeline Embolization of Unruptured Intracranial Aneurysms  Voir?

The choice of appropriate antiplatelet therapy prior to the Pipeline Embolization Device (PED) placement is usually guided by platelet function testing such as light transmission aggregometry (LTA). In this study, we aimed to define the optimal threshold LTA value for clopidogrel responsiveness to predict the risk of post-procedural thromboembolic complications and to help guide appropriate antiplatelet regimen.

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Clinical Features and Treatment of Secondary Pituitary Abscess Following Transsphenoidal Surgery: A Retrospective Study of 23 Cases  Voir?

Pituitary abscess (PA) is a rare but serious intrasellar disorder with potentially high disability and mortality. Secondary PA following transsphenoidal surgery (TS) is extremely rare and only a few case reports were identified in the literature. This study explored the salient clinical manifestations and etiologies to determine appropriate treatment.

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Intracranial Aneurysm is Associated with High Intracranial Artery Tortuosity  Voir?

Although intracranial aneurysms (IA) are focal bulges of arterial walls, uncharacterized predisposing factor that affects cerebral arteries may increase the tortuosity of intracranial arteries in subjects with IA.
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Percutaneous endoscopic laminotomy with flavectomy by uniportal, unilateral approach for the lumbar canal or lateral recess stenosis  Voir?

The objective of this retrospective study was to evaluate the clinical feasibility and safety of percutaneous endoscopic decompression by uniportal, unilateral approach for the lumbar canal or lateral recess stenosis.
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Dose-dependent effects of statins for patients with aneurysmal subarachnoid hemorrhage: meta-regression analysis  Voir?

The study utilizes meta-regression analysis to quantify the dose-dependent effects of statin pharmacotherapy on vasospasm, delayed ischemic neurologic deficits (DINDs) and mortality in aneurysmal subarachnoid hemorrhage (aSAH).
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Marriage and partnership integrity after aneurysmal SAH: Small alterations in neurological status matter most  Voir?

Common sequelae of subarachnoid hemorrhage (SAH) include somatic and/or cognitive impairment. This can cause emotional stress, social tensions, and difficulties in relationships. To test our hypothesis that more severe somatic and cognitive impairments increased the likelihood of disruption of a relationship after SAH, we assessed the integrity of marriage or partnership status in a well-evaluated subset of SAH patients.; Abbreviations: GOSE: extended Glasgow outcome scale;mRS: modified Rankin scale;SAH: subarachnoid hemorrhage

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Prognostic significance of magnetic resonance imaging in patients with severe nonpenetrating traumatic brain injury requiring decompressive craniectomy  Voir?

Diffuse axonal injury (DAI) detected on magnetic resonance imaging (MRI) may be useful to predict outcome after traumatic brain injury (TBI).
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Transnasal transphenoidal elevation of optic chiasm in secondary empty sella syndrome following prolactinoma treatment  Voir?

Prolactinomas are typically treated non-surgically with a dopamine agonist. However, once the tumor shrinks, adjacent eloquent structures such as the optic apparatus can become skeletonized and herniate into the dilated parasellar space.
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Intracranial hypertension and cerebral autoregulation: a systematic review and meta-analysis  Voir?

The objective of this paper is to present a systematic review and meta-analysis to establish the relation between cerebral autoregulation (CA) and intracranial hypertension.
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Adrenal Axis Insufficiency Following Endoscopic Transsphenoidal Resection of Pituitary Adenomas  Voir?

Hormonal insufficiency of one or more pituitary axes can appear after pituitary surgery. Adrenal axis impairment after surgery can lead to serious consequences if not identified and treated.
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Morphometric analysis of uncinate process as a landmark for anterior controllable antedisplacement and fusion surgery: A study of radiological anatomy  Voir?

This study used uncinate process (UP) base as the landmark to measure the various distances of the interested anatomic structures, in order to improve the practicality of anterior controllable antedisplacement and fusion (ACAF) for ossification of the posterior longitudinal ligament (OPLL).
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A case of spinal osteoblastoma in the elderly: is it really a young patient’s disease?  Voir?

Osteoblastoma is a benign bone forming tumor, sometimes locally invasive, that may involve any bone. The highest incidence is between 20 and 30 years of age and there are no cases described in the elderly.
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A potential new risk factor for stroke: Streptococcus mutans with collagen-binding protein  Voir?

Among human oral bacteria, particular kinds of Streptococcus mutans (SM) known as dental caries pathogen have a collagen-binding protein called Cnm and show platelet aggregation inhibition and matrix metalloproteinase-9 activation. We have previously reported that these strains may be a risk factor for intracerebral hemorrhage. As a major sample providing hospital, we report here the clinical details including intracranial aneurysms and ischemic stroke.

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Relaxing Sphenoidal Slit Incision to Extend the Anterior and Posterior Reach of Pedicled Nasoseptal Flaps During Endoscopic Skull Base Reconstruction of Transcribriform Defects: Technical Note and Results in 20 Patients  Voir?

Reconstruction of large anterior skull base (ASB) defects after an endoscopic endonasal transcribriform approach (EEA-TC) remains a challenge despite the advent of the vascularized pedicled nasoseptal flap (PNSF).
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Minimally Invasive Approaches for Anterior Skull Base Meningiomas: Supraorbital Eyebrow, Endoscopic Endonasal, or a Combination of Both? Anatomic Study, Limitations, and Surgical Application  Voir?

Minimally invasive accesses to the anterior skull base include the endoscopic endonasal approach (EEA) and the supraorbital eyebrow approach. These 2 are often seen as competing approaches, not alternative or combinatory approaches. In this study, we evaluated the anatomic limitations of each approach and the combined approach for accessing the anterior skull base.

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Potential Uses of Isolated Toxin Peptides in Neuropathic Pain Relief: A Literature Review  Voir?

Neuropathic pain is a subset of chronic pain that is caused by neurons that are damaged or firing aberrantly in the peripheral or central nervous systems. The treatment guidelines for neuropathic pain include antidepressants, calcium channel α 2 delta ligands, topical therapy, and opioids as a second line option. Unfortunately, pharmacotherapy has not been effective in the treatment of neuropathic pain except in the treatment of trigeminal neuralgia with carbamazepine. The inability to properly treat neuropathic pain causes frustration in both the patients and their treating physicians.

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Factors Affecting Long-Term Postoperative Narcotic Use in Discectomy Patients  Voir?

Long-term narcotic use has risks and potentially life-threatening opioid-related side effects. Extended narcotic use in patients undergoing discectomy raises concerns of other underlying causes of pain or overprescription and/or abuse. The goal of this study was to determine which factors have an effect on active narcotic prescription >3 months after discectomy.

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Repeated endovascular treatments in patients with recurrent cerebral vasospasms after subarachnoid hemorrhage – a worthwhile strategy?  Voir?

Endovascular interventions in patients with subarachnoid hemorrhage (SAH) and symptomatic cerebral vasospasm (sCVS) are commonly performed. But potential benefits of repeated interventions have not been proven.The aim of this study was to show the potential burden and opportunities of repeated endovascular interventions in case of recurrent sCVS.

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World Health Organization Grade III (Nonanaplastic) Meningioma: Experience in a Series of 23 Cases  Voir?

Rhabdoid meningioma (RM) and papillary meningioma (PM) are rare variants of World Health Organization grade III meningiomas. In this study, we presented a series of 23 cases from our institution to investigate adverse factors of and appropriate treatment for RM and PM.
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Changes of Facet Joints after Dynamic Stabilization: Continuous Degeneration or Slow Fusion?  Voir?

The non-fusion pedicle-screw system Dynesys stabilization(DS) for lumbar degenerative disease aims to better preservation of range of motion(ROM) than fixation and fusion systems. However, decreased ROM and unexpected facet fusion at the index level were observed after DS applied with unknown etiology. The aim of this study is using radiological parameters to explain the phenomenon of facet arthrodesis.

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The pathogenesis of subacute subdural hematoma: A report of 3 cases and literature review  Voir?

This paper aims to discuss the pathological mechanism of subacute subdural hematoma (sASDH).
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Primary meningeal melanocytoma in sellar region, simulating a nonfunctioning pituitary adenoma; a case report and literature review  Voir?

and Importance Primary meningeal melanocytoma (PMM) is a benign lesion in the central nervous system derived from leptomeningeal melanocytes, most commonly growing in the posterior fossa and cervical spinal cord. The primary sellar melanocytoma is an exceptionally rare tumor. The authors reported the ninth published case of a sellar primary meningeal melanocytoma (SPMM).

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Pain-Free outcomes and Durability of Surgical Intervention for Trigeminal Neuralgia: A Comparison of Gamma Knife and Microvascular Decompression  Voir?

Procedural options for trigeminal neuralgia (TN) include microvascular decompression (MVD) and gamma knife surgery (GKS). Currently, there is no definitive consensus as to which of the two options is more effective at providing immediate and long-lasting pain relief. This study seeks to better evaluate the differences between these two options in terms of rates of complete pain relief and pain-free recurrence

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The effects of memantine on glutamic receptor associated nitrosative stress in a traumatic brain injury rat model  Voir?

The main aim of this study is to elucidate whether the neuroprotective effect of memantine, a non-competitive NMDA receptor 2B (NR2B) antagonist, affect neuronal nitrosative stress, apoptosis, and NR2B expression and ultimately improve functional outcomes.
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An Experimental Study on Repeated Brief Ischemia in Promoting Sciatic Nerve Repair and Regeneration in Rats  Voir?

Researches have shown that ischemic preconditioning reduced the severity of ischemia-reperfusion injury in brain in rats, we have a hypothesis that repeated brief ischemia has positive effects on peripheral nerve damage.
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Surgical Drains in Chronic Subdural Hematoma Surgery: From the Cheapest to the Most Expensive Drains  Voir?

Chronic subdural hematoma is a common neurosurgical condition, and over the years, various surgical techniques have been developed to treat this condition. Among the various neurosurgical techniques currently being used, burr hole craniostomy is the most popular worldwide. Recent studies have strongly recommended that a drain be placed after surgical evacuation of a hematoma, and a broad spectrum of preformed surgical drains is widely available for this purpose. If preformed drains are unavailable, a surgeon-made drain can be used, and various methods are available to develop a drain in the operating room.

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Anatomical Study of the Posterior Ascending Artery: Application to C2 Pedicle Screw Placement  Voir?

Anatomy of the posterior ascending artery (PAA) has been well documented. The PAA forms an apical arcade, which supplies the small branches to the tip of the dens. However, morphometrics of this artery such as diameter and distance from the midline, which could be applied to the diagnosis and surgical procedure, are scant. We aimed to investigate the anatomy of the PAA in order to apply our findings to surgical procedures such as C2 pedicle screw placement.

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Default Mode Network Changes in Moyamoya Disease Before and After Bypass Surgery: Preliminary Report  Voir?

Neurocognitive impairment is often reported in moyamoya disease. We aimed to detect default mode network (DMN) alterations using resting-state functional magnetic resonance imaging and their association with neurocognitive impairments. In addition, the influence of surgical treatment was individually evaluated.

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Ectopic Prolactinoma Presenting as Bacterial Meningitis: A Diagnostic Conundrum  Voir?

Prolactinomas may rarely present with meningitis and cerebrospinal fluid (CSF) rhinorrhea secondary to erosion of the wall of the sella turcica. It is even more un-common for this abnormal communication to be caused by an ectopic prolactinoma arising from the sphenoid sinus and eroding into the sella. This atypical growth pattern makes diagnosis very difficult, as there may be no displacement of the normal pituitary gland. The authors present the first reported case of a patient with an ectopic prolactinoma presenting primarily with meningitis, and discuss the management strategy as well as surgical and non-surgical treatment options for these patients.

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Cortical Reorganizations for Recovery from Depressive State After Spinal Decompression Surgery  Voir?

Depressed mood following neuronal damage not only impedes functional recovery but also negatively affects quality of life for many patients. Depressed patients with cervical myelopathy often show improvement in both mood and motor function after spinal decompression surgery; however, the neural mechanism underlying this psychological benefit from surgery remains unclear. The aim of this study was to clarify the brain sites that relate to alleviation of depression after spinal decompression surgery.

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Incidence, Comorbidities, and Mortality in Idiopathic Normal Pressure Hydrocephalus  Voir?

To investigate the incidence, comorbidities, mortality, and causes of death in idiopathic normal pressure hydrocephalus (iNPH).
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The Single Center Clinical Characteristics and Treatment Experiences of Foramen Magnum Neurenteric Cyst:Report of 6 cases and Brief Review of the Literature  Voir?

To retrospectively analyze the clinical data of 6 foramen magnum neurenteric cyst patients and summarizethe clinical characteristics and treatment experience for this rare disease in our single center.
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Identification of Stria Medullaris Fibers in the Massa Intermedia Using Diffusion Tensor Imaging  Voir?

The massa intermedia (MI) or interthalamic adhesion is an inconsistent band spanning between bilateral medial thalami that is absent in up to 20-30% of individuals. Little is known of its significance, especially in regards to functional pathways. Probabilistic diffusion tensor imaging (DTI) has recently been used to seed the lateral habenula (LHb) and define its afferent white matter pathway, the stria medullaris thalami (SM). We sought to determine if the MI serves as a conduit for crossing of limbic fibers such as the SM.

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Minimally Invasive Lateral Endoscopic Multiport Approach to the Infratemporal Fossa: A Cadaveric Study  Voir?

Expanded endoscopic endonasal approaches to the infratemporal fossa (ITF) are increasingly performed owing to improved visualization and less morbidity compared with classic open approaches. Only a few studies in the literature investigated lateral endoscopic access to the ITF. The aim of this study was to examine the ITF with the minimally invasive endoscopically assisted Gillies approach with a trial of its expansion through a double port technique.

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Stereotactic Radiofrequency thermocoagulation of hypothalamic hamartoma using Robotic guidance (ROSA) co-registered with O-arm guidance – Preliminary Technical Note  Voir?

Treatment options for hypothalamic hamartoma (HH) include microvascular surgery, stereotactic radiofrequency thermocoagulation (SRT), laser interstitial thermal therapy (LITT) or Gamma knife surgery (GKS). During SRT, thermographic monitoring cannot be performed and therefore highly accurate placement of electrode and confirmation of its position are required. We have utilized robotic guidance (ROSA) and co-registered it with O-Arm, for performing ablation of hamartoma.

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Acute Compartment Syndrome as a Complication of the Use of Intraoperative Neuromonitoring Needle Electrodes  Voir?

The use of intraoperative neurophysiologic monitoring (IOM) has become commonplace in many neurosurgical procedures as a tool to reduce the risk of complications through the early identification of reversible neurologic compromise. Although complications related to IOM itself are exceedingly rare, recognizing their clinical presentation in the postoperative neurosurgical patient is essential for the early identification and implementation of appropriate treatment.Case Description: The authors present a case report of a patient who developed postoperative acute compartment syndrome in the right arm after placement of neuromonitoring needles for routine IOM during endovascular treatment of a left internal carotid artery aneurysm.

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Effect of Tubastatin A on the functional recovery of cauda equina injury in rats  Voir?

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The Ultradense Middle Cerebral Artery: A specific sign of Cerebral Lipiodol Embolization  Voir?

Cerebral lipiodol embolization is a rare but known complication of lymphatic embolization for plastic bronchitis. The classic imaging finding on a noncontrast head CT is multiple small areas of hyperdensity within the cerebral hemispheres, which represent lipiodol deposition in the brain. We report a case of lipiodol deposition in the middle cerebral artery following lymphatic embolization, producing an 'ultradense' vessel sign on noncontrast CT.

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Continuous acetylsalicylic acid treatment does not influence bleeding pattern or outcome of aneurysmal subarachnoid hemorrhage: a matched pair analysis  Voir?

Demographic changes are leading to an aging society with a growing number of patients with cardiovascular diseases, relying on antiplatelet drugs like acetylsalicylic acid (ASA). Although antiplatelet agents are suspected to be protective not only in the cardiological but in the neurovascular field, the alteration of the coagulating process could have a major impact on the course and outcome after rupture of intracranial aneurysms.

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True cortical saccular aneurysm presenting as an acute subdural hematoma  Voir?

Subdural hematoma, without any radiographic evidence of subarachnoid hemorrhage, is a rare presentation of a ruptured intracranial aneurysm. Even more rare is the occurrence of a pure subdural hematoma due to a ruptured cortical saccular aneurysm. We report the eighth case of pure subdural hematoma secondary to a ruptured non-mycotic cortical berry aneurysm.

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Relationship Between Citation-Based Scholarly Activity of United States Radiation Oncology Residents and Subsequent Choice of Academic versus Private Practice Career  Voir?

Posttraumatic hydrocephalus (PTH) and posthemorrhagic hydrocephalus (PHH) were previously considered not suitable for neuroendoscopic treatment. New hydrocephalus theories support possible successful neuroendoscopy in such patients.
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International Neurosurgical Care: Attending to Those in Need  Voir?

A woman dies months after hemiplegia slowly begins and gradually progresses to coma. It shouldn't happen. But it does. A 2 year-old with a deep scalp ulceration from lying on one side too long, the head too large and the body too frail to change position, stops eating and dies. It shouldn't happen. But it does. A young man overturns a motorcycle, strikes his head, dilates a pupil and an hour later lapses into coma and dies. It shouldn't happen. But it does.

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Knowledge and Attitude Regarding Radiation Exposure Amongst Spine Surgeons: Latin America  Voir?

Spine surgeons are exposed to high amounts of radiation from fluoroscopic procedures during their lifetime. The objective is to evaluate spine surgeons’ knowledge and attitude regarding radiation exposure during spine surgery.
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The Most Cited Works in Severe Traumatic Brain Injury: A Bibliometric Analysis of the 100 Most Cited Articles  Voir?

There is an abundance of works published on severe traumatic brain injury (sTBI). Bibliometric analyses are aiming to have a macroscopic view of research activities about sTBI and are helpful in determining the most impactful studies within this field.
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Comparison of adjuvant radiation therapy alone and chemotherapy alone in surgically resected low-grade gliomas: survival analyses of 2253 cases from the National Cancer Data Base  Voir?

It is becoming increasingly common to incorporate chemotherapy (CT) with radiotherapy (RT) in the treatment of low-grade gliomas (LGGs) after surgical resection. However, there is a lack of literature comparing survival of patients who underwent RT and CT alone.
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The efficacy of cauda epidural steroid injections with targeted indwelling catheter and manipulation in managing patients with lumbar disc herniation with radiculopathy: a prospective, randomized, single-blind controlled trial  Voir?

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Mortality after Spontaneous Subarachnoid Hemorrhage: Causality and Validation of a Prediction Model  Voir?

To evaluate primary causes of death after spontaneous subarachnoid hemorrhage (SAH) and externally validate the HAIR score, a prognostication tool, in a single academic institution.
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Clinical and radiological features of Three Reconstructive Procedures for the Surgical Management of Patients with Bi-level Cervical Degenerative Disc Disease at a Minimum Follow Up Period of Five Years: A Comparative Study  Voir?

To assess the mid-long-term follow-up of the safety and efficacy of anterior cervical discectomy and fusion (ACDF), cervical artificial disc replacement (CADR) and hybrid surgery (HS) for bi-level cervical degenerative disc disease (cDDD).
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Impact of Additional Treatment of Paralumbar Spine and Peripheral Nerve Diseases After Lumbar Spine Surgery  Voir?

Some patients experience failed back surgery syndrome after lumbar spine surgery. We report the effect of additional treatments for paralumbar spine and peripheral nerve diseases addressing residual symptoms after surgery.
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Supratentorial Cortical Ependymomas: A Retrospective Series of 13 Cases at a Single Center  Voir?

Cortical ependymomas (CEs), supratentorial ependymoma that selectively involve the cerebral cortex, is relatively rare neoplasm which have not been extensively described. The purpose of our study was to identify the clinical features, radiologic characteristics, and treatment of a series of such tumors.

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Scanning fiber endoscope improves detection of 5-ALA induced protoporphyrin IX fluorescence at the boundary of infiltrative glioma  Voir?

Fluorescence-guided surgery with protoporphyrin IX (PpIX) as a photodiagnostic marker is gaining acceptance for resection of malignant gliomas. Current wide-field imaging technologies do not have sufficient sensitivity to detect low PpIX concentrations. We evaluated a scanning fiber endoscope (SFE) for detection of PpIX fluorescence in gliomas and compared it with an operating microscope (OPMI) equipped with fluorescence module and a benchtop confocal laser scanning microscope (CLSM).

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Hypertrophic Olivary Degeneration: Neurosurgical Perspective and Literature Review  Voir?

Hypertrophic olivary degeneration (HOD) occurs as a result of posterior fossa or brainstem lesions that disrupt the dentato-rubro-olivary tract, well known as the Guillain-Mollaret triangle. Clinical and radiological hallmarks of this condition are palatal myoclonus and T2 hyperintensity of the inferior olivary complex on MRI, respectively. Since symptomatic HOD may complicate the recovery of patients with posterior fossa or brainstem lesions, the purpose of this study is to evaluate clinical and imaging findings of patients with HOD.

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Telemedicine for Neurotrauma in Albania: Initial Results from a Case Series of 146 Patients  Voir?

Use of telemedicine for neurotrauma when performed by neurosurgeons is an innovative care option for traumatic brain injury (TBI) patients, particularly in countries with limited neurosurgery expertise resources. In recent years, Albania has developed a robust telemedicine program and teleneurotrauma is the flagship of the program. We aimed to evaluate the outcomes of the first neurotrauma patients managed via telemedicine in Albania.

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A case of primary central nervous system lymphoma arising at the site of remote herpes encephalitis.  Voir?

Primary central nervous system lymphoma (PCNSL) is a rare malignancy that usually arises in the context of severe immunosuppression, but has incompletely understood etiology, limiting effective treatments.
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Incidence and Risk Factors for Facet Joint Violation in Open Versus Minimally Invasive Procedures During Pedicle Screw Placement in Patients with Trauma  Voir?

A possible risk factor for premature facet joint degeneration or adjacent segment degeneration after surgical treatment of spine fractures is facet joint violation (FV) during insertion of pedicle screws. The aim of this study was to determine risk factors for FV in the thoracic and lumbar spine after minimally invasive screw insertion or open instrumentation (OI).

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When Are Complications After Brain Tumor Surgery Detected?  Voir?

To optimize follow-up and surveillance routines after intracranial surgery, knowledge about when complications occur is needed. We sought to explore when postoperative complications are detected after brain tumor surgery and assess their severity.
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Analysis of Four Scoring Systems for the Prognosis of Patients with Metastasis of the Vertebral Column  Voir?

Metastatic spinal diseases are common health problems and there is no consensus on the appropriate treatment of metastases in several conditions. Using clinical measures (e.g., survival time and functional status), prognosis prediction systems advise on the appropriate interventions. The aim of this article is to assess and compare 4 widely used scoring systems (revised Tokuhashi, Tomita, van der Linden, and modified Bauer scores) on a single-center cohort.

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Dural repair in cranial surgery is associated with moderate rates of complications with both autologous and non-autologous dural substitutes  Voir?

Duraplasty, a common neurosurgical intervention, involves synthetic or biological graft placement to ensure dural closure. The objective of this study is to advance our understanding of the use of dural substitutes in cranial surgery.
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A Large Multicenter Retrospective Research on Embedded Cranioplasty and Covered Cranioplasty  Voir?

Cranioplasty (CP) can be either embedded or covered, according to the implants used. However, determining which one is better in treating cranial defects is difficult. This study aimed to compare the clinical outcomes and complications of embedded CP and covered CP.
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Is Eighty the New Sixty? Outcomes and Complications after Lumbar Decompression Surgery in Elderly Patients over 80 Years of Age  Voir?

An increasing demographic aging of the general population results in a rising incidence of octogenarians and nonagenarians with spine disease. Patients older than 65 years represent the majority of patients with degenerative lumbar spine disease in our daily clinical routine. Surgical treatment is undertaken reluctantly because of an increased rate of comorbidities. We therefore assessed complication rates of lumbar decompression in regard to neurological outcome and medical conditions in patients age 80 years or older in a retrospective single-center series.

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Using the Reversed Temporal Island Flap to Cover Small Forehead Defects from Titanium Mesh Exposure After Cranial Reconstruction  Voir?

Skin ulcers and alloplastic implant exposure are intractable complications that arise after cranial defect reconstruction. Many methods have been used to repair these defects, including skin grafting, local flaps, and free flaps; however, in most cases, alloplastic implants must be removed to control infections. Here, we describe the use of a reversed temporal island flap to repair exposed titanium mesh without removing it.

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Pretherapeutic Functional Imaging Allows Prediction of Head Tremor Arrest After Thalamotomy for Essential Tremor: The Role of Altered Interconnectivity Between Thalamolimbic and Supplementary Motor Circuits  Voir?

To correlate pretherapeutic resting-state functional magnetic resonance imaging (rs-fMRI) measures with pretherapeutic head tremor presence and/or further improvement 1 year after stereotactic radiosurgical thalamotomy (SRS-T) for essential tremor (ET).
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Malignant peripheral nerve sheath tumor of the trigeminal nerve involving the middle and posterior cranial fossa  Voir?

Although benign trigeminal schwannomas are uncommon, malignant peripheral nerve sheath tumors (MPNSTs) of the trigeminal nerve are extraordinarily rare. This study aimed to describe an exceedingly rare case of MPNST of the trigeminal nerve involving the middle and posterior cranial fossa. Only 20 similar cases of MPNSTs of the trigeminal nerve have been reported so far. The clinical characteristics and management of these extremely rare tumors have also been explored in this study.

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Cervical Epidural Hematoma that Induced Sudden Paraparesis After a Cervical Spine Massage: A Case Report and Literature Review  Voir?

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A novel C2 screw trajectory: Preliminary anatomical feasibility and biomechanical comparison  Voir?

Pedicle screw and translaminar screw fixation in C2 may not be applicable in many patients with anatomical abnormalities or narrow laminar thickness and spinous process height. The objective of the current study was to assess the morphometric and mechanical feasibilities of a novel alternate C2 screw trajectory.

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The potential of minimally invasive surgery to treat metastatic spinal disease versus open surgery: a systematic review and meta-analysis.  Voir?

and Purpose: Metastasis to the spinal column is a common feature of primary tumors of breast, prostate, lung and other organs. Currently surgical intervention can be performed via the traditional open surgery (OS) approach or the minimally invasive surgery (MIS) approach. This study aims to assess the available evidence of perioperative outcomes of MIS vs OS for metastatic spinal disease patients.

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From Hypothermia to Cephalo-somatic Anastomoses: the legacy of Robert White (1926-2010) at Case Western Reserve University of Cleveland  Voir?

Dr. Robert J. White (1926-2010) was an eminent neurosurgeon and bioethicist, renowned for his classic work in hypothermia and pioneering mammalian head transplant experiments. He founded the Division of Neurosurgery at the Cleveland Metropolitan General Hospital (currently MetroHealth Medical Center, a level 1 Trauma County Hospital) and eventually became the youngest full Professor at the Case Western Reserve University in Cleveland, Ohio. With over 500 research papers to his credit, he founded the Brain Research Laboratory at what was then the Cleveland Metropolitan General Hospital which was also home to future leaders in Neurosurgery, Neurosciences and allied specialties.

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Adjustable polyurethane foam as filling material for a novel spondyloplasty: biomechanics and biocompatibility  Voir?

To investigate the biomechanics and biocompatibility of polyurethane (PU) foam with adjustable stiffness as a filling material for a novel spondyloplasty that is designed to reduce the risk of postoperative adjacent level fractures.
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A Comparison of Cerebellar Retraction Pressures in Posterior Fossa Surgery: Extended Retrosigmoid Versus Traditional Retrosigmoid Approach  Voir?

The retrosigmoid approach is broadly applicable to many procedures in the posterior fossa. However, cerebellar retraction is often necessary for lesions in the cerebellopontine (CP) angle which can lead to complications. An extended retrosigmoid approach skeletonizes the sigmoid sinus and allows a wider corridor with less retraction. This study aimed to investigate the differences in retraction pressure between the retrosigmoid and extended retrosigmoid approach in a cadaver model.

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Multimodality Management of Vein of Galen Malformations - an institutional experience  Voir?

The Vein of Galen Aneurysmal Malformation (VGM) is a rare intracranial arterio-venous fistula with a dramatic manifestation during infancy and a 100% mortality without treatment. Therapeutic strategies for VGMs have changed over time due to advances in endovascular techniques. We present our experience and multimodality approach within the last 4 decades.

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Misclassification of Case Control Studies in Neurosurgery and Proposed Solutions  Voir?

Case control and cohort studies are common research designs in neurosurgery. But the term “case–control study” (CCS) is frequently misused in the neurosurgical literature with many articles reported as CCS, even though their methodology does not respect the basic components of a CCS. We sought to estimate the extent of these discrepancies in neurosurgical literature, explore factors contributing to mislabeling and shed some light on study design reporting.

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Percutaneous transforaminal endoscopic discectomy for adjacent segment disease after lumbar fusion in elderly patients over 65 years old  Voir?

The aim of the study was to evaluate the short-term efficacy and safety of percutaneous transforaminal endoscopic discectomy (PTED) in the treatment of symptomatic ASD after lumbar fusion in elderly patients over 65 years old.
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Novel segmentation of placed coils in the treatment of cavernous sinus dural arteriovenous fistulas provides a reliable predictor of the long-term outcome in abducens nerve palsy  Voir?

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Endoscopic Endonasal Transphenoidal ApproachVisual Outcome in Pituitary Macroadenomas: Quantitative Assessment with Diffusion Tensor imaging (DTI): Early and Long Term Results  Voir?

Postoperative visual recovery in patients with pituitary adenoma can be influenced by the duration of symptoms, age, and tumor volume. Diffusion tensor imaging (DTI) allows visualization of white matter structure along with quantitative information. The aims of our study were to predict the visual recovery process in the early and long-term periods and to define the parameters affecting the recovery course.

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Use of Pipeline Embolization Device for Posterior Circulation Aneurysms: Single-Center Experiences with Comparison with Anterior Circulation Aneurysms  Voir?

To evaluate the performance of the Pipeline embolization device (PED) for posterior circulation aneurysms.
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Association Between Neurological Outcomes Related to Aneurysmal Subarachnoid Hemorrhage and Onsite Access to Neurointerventional Radiology  Voir?

An onsite access to neurointerventional radiology (NIR) may be useful for managing patients with aneurysmal subarachnoid hemorrhage (aSAH) after the aneurysm-securing procedure. We aimed to assess the association between neurological outcomes related to aSAH and onsite access to NIR service.
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Local Spinal Cord Decompression through a Full-endoscopic Percutaneouus Transcorporeal Approach for the Cervicothoracic Ossification of the Posterior Longitudinal Ligament at the T1-T2 Level:A Technical Note  Voir?

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Diffusion Tensor Imaging of Axonal and Myelin Changes in Classical Trigeminal Neuralgia  Voir?

Trigeminal neuralgia (TN) is commonly associated with pathologic factors of axonopathy and demyelination resulting from neurovascular compression at the trigeminal root entry zone (REZ). Decompression surgery can relieve TN pain, likely by resolving such structural abnormalities. To test this hypothesis, we used diffusion tensor imaging (DTI) to capture the full extent of trigeminal microarchitecture changes in vivo in patients with TN.

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Comparison of 4 Different Methods for Direct Hypoglossal-Facial Nerve Anastomosis in Rats  Voir?

Classic hypoglossal–facial nerve anastomosis inevitably causes hemitongue atrophy and dysfunction. Thus, many variants have been developed to reduce tongue-related morbidities. A comparative study concerning these techniques was conducted in rats to systematically evaluate long-term functional and histologic outcomes of the recipient and donor systems.

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Hemorrhagic complications of arachnoid cysts: When, Why and Who?  Voir?

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Initial Attempt to Select Patients for Mechanical Thrombectomy Using Noncontrast Computed Tomography and Symptom-Based Criteria: Single-Center Experience  Voir?

In the treatment of acute ischemic stroke (AIS), patients need to be selected for mechanical thrombectomy (MT) in the acute phase. Selection criteria vary, however, depending on the patient's situation. This study investigated the effectiveness of a noncontrast computed tomography and symptom-based protocol for selecting patients for MT.

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Intracranial Pressure: A Comparison of the Noninvasive HeadSense Monitor versus Lumbar Pressure Measurement  Voir?

To compare a new method of noninvasive intracranial pressure (nICP) measurement with conventional lumbar puncture (LP) opening pressure.
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Corrigendum to “In Reply to the Letter to the Editor Regarding “Endoscopic Endonasal Surgery for Pituitary Apoplexy: Evidence On a 75 Case-Series From a Tertiary Care Center”” [World Neurosurgery 109 (2018) 502]  Voir?

The authors regret that their names and surnames were reversed in the author list in the original published article. The correct author list is the following: Matteo Zoli, Laura Milanese, Marco Faustini-Fustini, Federica Guaraldi, Sofia Asioli, Corrado Zenesini, Alberto Righi, Giorgio Frank, Maria Pia Foschini, Carmelo Sturiale, Ernesto Pasquini, Diego Mazzatenta.

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Accuracy of Susceptibility-Weighted Imaging and Dynamic Susceptibility Contrast Magnetic Resonance Imaging for Differentiating High-Grade Glioma from Primary Central Nervous System Lymphomas: Meta-Analysis  Voir?

It is always a great challenge to distinguish high-grade glioma (HGG) from primary central nervous system lymphoma (PCNSL). We conducted a meta-analysis to assess the performance of dynamic susceptibility contrast (DSC) and susceptibility-weighted imaging (SWI) in differentiating HGGs from PCNSLs.
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Early Stereotactic Radiosurgery for Medically Refractory Trigeminal Neuralgia  Voir?

To evaluate effectiveness of early Gamma Knife radiosurgery (GKRS) in treatment of medically refractory trigeminal neuralgia (TN).
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Clinical and Radiologic Results of Anterior Cervical Discectomy and Fusion for Cervical Spondylotic Myelopathy in Elderly Patients with T2-Weighted Increased Signal Intensity  Voir?

To investigate clinical and radiologic results of anterior cervical discectomy and fusion for cervical spondylotic myelopathy in elderly patients with T2-weighted increased signal intensity (ISI), focusing specifically on the quantitative analysis of ISI.
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The Radiographic Effects of Surgical Approach and Use of Retractors on the Brain After Anterior Cranial Fossa Meningioma Resection  Voir?

There is an increasing trend toward skull base (SB) approaches and retractorless surgery to minimize brain manipulation during surgery. We evaluated the radiographic changes over time after surgical resection of anterior cranial fossa meningiomas with and without both SB approaches and/or fixed retractor systems.

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The Role of Neurosurgery in Countries with Limited Facilities: Facts and Challenges  Voir?

The Lancet Commission on Global Surgery has recently focused its attention on the lack of surgical care worldwide. Like other surgical subspecialties, neurosurgical care needs to be better distributed around the world, with a major focus on low- to middle-income countries. Neurosurgical diseases like hydrocephalus, traumatic brain injury, and brain tumors have a high impact on families, individual quality of life, and cost for the society. Implementation of neurosurgical care in poor settings is not easy.

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Coloring Technique of Magnetic Resonance Angiography for Superficial Temporal Artery to Middle Cerebral Artery Bypass Surgery  Voir?

Superficial temporal artery (STA)–to–middle cerebral artery (MCA) bypass is an established surgical technique for achieving revascularization. It is important to select the proper recipient artery of the MCA. Three-dimensional computed tomographic angiography (3D-CTA) and conventional angiography are useful in the selection process but need contrast agents. The authors have designed a coloring MRA technique that needs no agents to visualize the recipient artery. Retrospective evaluation of the efficacy and limitation for selection of the recipient artery and decision of the place and size of the craniotomy were carried out.

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Somatotrophic Adenoma in Children Younger than 14 Years: Clinical Features and Treatment of 22 Cases at a Large Pituitary Center  Voir?

To investigate the clinical features of somatotrophic adenoma in children younger than 14 years and to evaluate the short-term and long-term outcomes of transsphenoidal surgery.
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Frailty and Health-Related Quality of Life Improvement Following Adult Spinal Deformity Surgery  Voir?

Although the Adult Spinal Deformity Frailty Index (ASD-FI) predicts major complications and prolonged hospital length of stay after adult spinal deformity surgery, the impact of frailty on postoperative changes in health-related quality of life (HRQoL) is unknown.
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Occipital Artery and Its Segments in Vertebral Artery Revascularization Surgery: A Microsurgical Anatomic Study  Voir?

To study the microsurgical anatomy of the occipital artery (OA) to determine the optimal segment for use as a conduit in revascularization bypass surgery.
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Genetic Variations of the COL4A1 Gene and Intracerebral Hemorrhage Risk: A Case-Control Study in a Chinese Han Population  Voir?

To investigate the association between single nucleotide polymorphisms or haplotypes of the COL4A1 gene and the risk of intracerebral hemorrhage (ICH).
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Motor Cortex Reorganization in Patients with Glioma Assessed by Repeated Navigated Transcranial Magnetic Stimulation–A Longitudinal Study  Voir?

Evidence for cerebral reorganization after resection of low-grade glioma has mainly been obtained by serial intraoperative cerebral mapping. Noninvasively collected data on cortical plasticity in tumor patients over a surgery-free period are still scarce. The present study therefore aimed at evaluating motor cortex reorganization by navigated transcranial magnetic stimulation (nTMS) in patients after perirolandic glioma surgery.

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Current Perspectives in Imaging Modalities for the Assessment of Unruptured Intracranial Aneurysms: A Comparative Analysis and Review  Voir?

Intracranial aneurysms (IA) are pathological dilatations of cerebral arteries. This systematic review summarizes and compares imaging techniques for assessing unruptured intracranial aneurysms (UIAs). This review also addresses their uses in different scopes of practice. Pathophysiologic mechanisms are reviewed to better understand the clinical utility of each imaging modality.

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Outcomes of Microsurgical Clipping of Recurrent Aneurysms After Endovascular Coiling  Voir?

The outcomes of microsurgery of previously coiled aneurysms have been poorly described, and little is known about the factors predictive of poor outcome. Here we aimed to identify predictors of poor outcome following microsurgery for previously coiled recurrent aneurysms.
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Continuous lumbar cistern drainage before surgical clipping for aneurysmal subarachnoid hemorrhage  Voir?

Lumbar drainage (LD) is the choice for the treatment of acute hydrocephalus and increased intracranial pressure in patients with subarachnoid hemorrhage (SAH). It also reduces vasospasm risk and delayed ischemic neurological events. We evaluated the role of LD in the preoperative management of patients with aneurysmal SAH (aSAH).

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Fusion Rate and Clinical Outcomes in Two-Level Posterior Lumbar Interbody Fusion  Voir?

Posterior lumbar interbody fusion (PLIF) has become a general surgical method for degenerative lumbar diseases. Although many reports have focused on single-level PLIF, few have focused on 2-level PLIF, and no report has covered the fusion status of 2-level PLIF. The purpose of this study is to investigate clinical outcomes and fusion for 2-level PLIF by using a combination of dynamic radiographs and multiplanar-reconstruction computed tomography scans.

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Surgical Results of Common Peroneal Nerve Neuroplasty at Lateral Fibular Neck  Voir?

Common peroneal nerve (CPN) compressive neuropathy is the most common lower-extremity entrapment neuropathy.
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Risk Factors Analyses for Seizure Recurrence in Different Periods After Refractory Epilepsy Surgery: A Prospective Single-Center Study  Voir?

To evaluate the potential risk factors associated with seizure recurrence in different periods after epilepsy surgery.
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Surgical Management of Myelomeningocele-Related Spinal Deformities  Voir?

To evaluate the optimal timing and type of surgical treatment of myelomeningocele (MMC)-related spinal deformities and long-term follow-up of surgical treatment.
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CyberKnife Radiosurgery in the Multimodal Management of Patients with Cushing Disease  Voir?

Surgery is the primary treatment for Cushing disease. When surgery is unsuccessful in normalizing hypercortisolism, adjuvant radiation, such as stereotactic radiosurgery, may be useful to improve biochemical control.
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Microvascular Brainstem Ischemia After Vestibular Schwannoma Surgery: A Clinical and Microanatomic Study  Voir?

To identify a potential microvascular etiology in patients who underwent vestibular schwannoma surgery (VSS) complicated by postoperative microvascular brainstem ischemia.
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Correlation Between Tumor Location and Clinical Properties of Glioblastomas in Frontal and Temporal Lobes  Voir?

Tumor location is a major prognostic factor in glioblastomas and may be associated with clinical properties. This study established and analyzed the correlation between tumor location and clinical properties of glioblastomas in frontal and temporal lobes.
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Awake Surgery for Gliomas within the Right Inferior Parietal Lobule: New Insights into the Functional Connectivity Gained from Stimulation Mapping and Surgical Implications  Voir?

Little is known about the functional role of the white matter connections running within and around the right inferior parietal lobule (IPL). We used direct electrostimulation during awake surgery to investigate this connectivity and to avoid permanent deficit after resection for right IPL gliomas.
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Seizures After Intracerebral Hemorrhage: Incidence, Risk Factors, and Impact on Mortality and Morbidity  Voir?

Spontaneous intracerebral hemorrhage (ICH) is one of the most frequent causes of epilepsy in the United States. However, reported risk factors for seizure after are inconsistent, and their impact on inpatient morbidity and mortality is unclear. We aimed to study the incidence, risk factors, and impact of seizures after ICH in a nationwide patient sample.

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Surgical Approaches for the Treatment of Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: Results of a Decision Analysis  Voir?

Ossification of the posterior longitudinal ligament (OPLL) often leads to cervical myelopathy. Although multiple procedures have been shown to be effective in the treatment of OPLL, outcomes are less predictable than in degenerative cervical myelopathy, and surgery is associated with high rates of complications and reoperation, which affect quality of life. In this study, we performed a decision analysis using postoperative complication data and health-related quality of life (HRQoL) utility scores to assess the average expected health utility and 5-year quality-adjusted life years (QALYs) associated with the most common surgical approaches for multilevel cervical OPLL.

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Clinical Utility of Serum Procalcitonin Level and Infection in the Neurosurgical Intensive Care Unit  Voir?

Procalcitonin, a bloodstream inflammatory biomarker, has proven useful in the diagnosis of sepsis in critically ill patients treated in medical and surgical intensive care units. This study aims to further our understanding of the significance of procalcitonin levels in neuroscience intensive care unit (NICU) patients.

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Endovascular Mechanical Thrombectomy for Acute Ischemic Stroke Under General Anesthesia Versus Conscious Sedation: A Systematic Review and Meta-Analysis  Voir?

Endovascular mechanical thrombectomy (EMT) is the standard of care for eligible patients presenting with anterior circulation acute ischemic stroke (AIS) due to emergent large vessel occlusion (ELVO). The aim of this systematic review and meta-analysis is to compare the outcomes between patients undergoing general anesthesia (GA) versus conscious sedation (CS) for these procedures.

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Preoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity  Voir?

Measures of health care use such as length of hospital stay (LOS) are used as proxies for quality of care after spine surgery. Accordingly, hospitals and health systems are investing considerable resources into the preoperative identification of patients at risk for prolonged LOS. This study aims to investigate the impact of preoperative level on outcomes and LOS after spinal fusion.

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Endovascular Treatment of Middle Cerebral Artery Dissecting Aneurysms: A 7-Year Single-Center Study  Voir?

To evaluate safety and efficacy of endovascular treatment of middle cerebral artery dissecting aneurysms (MCADAs).
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Estrogen Receptor-α is Involved in Tamoxifen Neuroprotective Effects in a Traumatic Brain Injury Male Rat Model  Voir?

To determine the neuroprotective mechanisms of tamoxifen (TMX) during traumatic brain injury (TBI), especially the effects on estrogen receptor-α (ERα) expression, as well as neuroinflammatory associations.
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Endoscopic Endonasal Craniofacial Surgery for Recurrent Skull Base Meningiomas Involving the Pterygopalatine Fossa, the Infratemporal Fossa, the Orbit, and the Paranasal Sinus  Voir?

Skull base meningiomas carry a nonnegligible risk of recurrence. In particular, those arising from the sphenoid wings or middle cranial fossa penetrate into extracranial regions, uncommonly showing massive expansion into the craniofacial regions on recurrence. The role of endoscopic endonasal surgery for those intractable lesions remains unclear.

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Internal Thoracic Artery to Middle Cerebral Artery Bypass Surgery: Cadaveric Feasibsility Study  Voir?

A few options of extracranial donor vessels exist for use in intracranial vascular bypass procedures. To our knowledge, the use of an internal thoracic artery for cerebral revascularization has not been studied previously. Hence, this cadaveric feasibility study was performed.
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Primary Obstruction of the Foramen of Luschka: Anatomy, Histology, and Clinical Significance  Voir?

The foramen of Luschka is a natural aperture between the fourth ventricle and the subarachnoid space at the cerebellopontine angle. Membranous closure of this foramen is referred to as primary obstruction. Available information about this variant and its role in the development of the cysts of the posterior fossa is contradictory.

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The Prognostic Roles of Gender and O6-Methylguanine-DNA Methyltransferase Methylation Status in Glioblastoma Patients: The Female Power  Voir?

Clinical and molecular factors are essential to define the prognosis in patients with glioblastoma (GBM). O6-methylguanine-DNA methyltransferase (MGMT) methylation status, age, Karnofsky Performance Status (KPS), and extent of surgical resection are the most relevant prognostic factors. Our investigation of the role of gender in predicting prognosis shows a slight survival advantage for female patients.

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Aggressive Resection of Congenital Lumbosacral Lipomas in Adults: Indications, Techniques, and Outcomes in 122 Patients  Voir?

The authors reviewed the treatment of adult patients with congenital intraspinal lipomas with total/near-total resection and discussed their preoperative characteristics, prognostic factors, and surgical outcomes.
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Is Early Tracheostomy Better for Severe Traumatic Brain Injury? A Meta-Analysis  Voir?

Tracheostomy has proven benefits for patients requiring prolonged mechanical ventilation. However, whether early tracheostomy (ET; <10 days after injury) can also improve outcomes in patients with severe traumatic brain injury (TBI) (Glasgow Coma Scale score ≤8) remains controversial. The aim of this study was to clarify this question.

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Virtual Cerebral Aneurysm Clipping with Real-Time Haptic Force Feedback in Neurosurgical Education  Voir?

Realistic, safe, and efficient modalities for simulation-based training are highly warranted to enhance the quality of surgical education, and they should be incorporated in resident training. The aim of this study was to develop a patient-specific virtual cerebral aneurysm-clipping simulator with haptic force feedback and real-time deformation of the aneurysm and vessels.

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Prognostic Factors for Survival Outcome of High-Grade Multicentric Glioma  Voir?

The purpose of this study was to perform a survival analysis of patients with high-grade multicentric gliomas and to assess the influence of various prognostic factors on overall survival (OS).
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Canadian Neurosurgery Educators' Views on Stereotactic Radiosurgery in Residency Training  Voir?

Despite the increasing prominence of stereotactic radiosurgery (SRS) in treating intracranial and spinal pathologies, there is currently a dearth of exposure to this modality in the neurosurgical residency. To address this gap, the aim of this study is to assess neurosurgery educators' views regarding the current state of SRS exposure, and to identify potential approaches to improve residency education in this domain.

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Intraoperative Flow Cytometry Enables the Differentiation of Primary Central Nervous System Lymphoma from Glioblastoma  Voir?

Accurate preoperative and intraoperative differentiation between primary central nervous system lymphoma (PCNSL) and glioblastoma (GBM) is sometimes difficult. Distinguishing between these tumors during surgery is important because surgical treatment is different between the 2 tumors. In this study, we established a new method of intraoperative differentiation between PCNSL and GBM using intraoperative flow cytometry (iFC), and we retrospectively tested whether iFC was useful for the intraoperative diagnosis of PCNSL and GBM.

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Blood Ethanol Levels Are Not Related to Coagulation Changes, as Measured by Thromboelastography, in Traumatic Brain Injury Patients  Voir?

Brain injury is a leading cause of death and disability in trauma patients. Ethanol (EtOH) use near the time of injury may contribute to worse outcomes in these patients by exacerbating coagulopathy. There are limited data regarding the effects of EtOH on coagulation and progression of traumatic intracranial hemorrhage (TICH).

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Impact of Platelet Transfusion on Intracerebral Hemorrhage in Patients on Antiplatelet Therapy–An Analysis Based on Intracerebral Hemorrhage Score  Voir?

Platelet transfusions for patients with intracerebral hemorrhage (ICH) on antiplatelet therapy (APT) remain controversial. Diverging past research and differences in platelet preparation warrant further investigation of this topic. In this study, the association between platelet transfusion and clinical outcomes of ICH is investigated in patients matched by ICH score, a validated predictor of mortality.

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Abdominal Pseudocysts and Peritoneal Catheter Revisions: Surgical Long-Term Results in Pediatric Hydrocephalus  Voir?

An abdominal pseudocyst (APC) is a distal catheter site-specific failure in patients treated with ventriculoperitoneal shunts. Few studies with more than 10 patients have been reported. The aim of this study was to analyze causes of peritoneal catheter revisions with special emphasis on revisions because of an APC.

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Perineural Spread of Melanoma to the Brachial Plexus: Identifying the Anatomic Pathway(s)  Voir?

Perineural spread of melanoma is a well-known mechanism of metastasis in cases involving cranial nerves. Brachial plexus involvement is rare, and the pathway is unknown.
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Comparison of MED and PELD in the Treatment of Adolescent Lumbar Disc Herniation: A 5-Year Retrospective Follow-Up  Voir?

To compare the efficacy and safety of minimally endoscopic discectomy (MED) and percutaneous endoscopic lumbar discectomy (PELD) in the treatment of adolescent lumbar disc herniation (ALDH).
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Neurosurgical Care: Availability and Access in Low-Income and Middle-Income Countries  Voir?

An estimated 5 billion people worldwide lack access to basic surgical care. In particular, the vast majority of low-income and middle-income countries (LMICs) currently struggle to provide adequate neurosurgical services. Significant barriers exist, including limited access to trained medical, nursing, and allied health staff; lack of equipment; and availability of services at reasonable distance and at reasonable cost to patients. An accurate assessment of current neurosurgical capacity in LIMCs is an essential first step in tackling this deficit.

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Results of Biopsy-Proven Sellar Germ Cell Tumors: Nine Years' Experience in a Single Center  Voir?

The biopsy is recognized as the most accurate method to determine the histologic characterization of sellar germ cell tumors. It is difficult to evaluate the prognosis before histologic confirmation.
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Endovascular Treatment of Intracranial Aneurysms Concomitant with Severe Adjacent Atherosclerotic Stenosis  Voir?

To investigate the effect and safety of endovascular treatment of intracranial aneurysms concomitant with severe adjacent atherosclerotic stenosis.
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Carotid Atherosclerotic Plaque Features in Patients with Acute Ischemic Stroke  Voir?

To investigate the carotid atherosclerotic plaque features in patients with acute ischemic stroke.
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Skip Hemilaminectomy for Large, Multilevel Spinal Epidural Hematomas: Report of a Series of 11 Patients  Voir?

We present our experience with a modification of the conventional techniques for the removal of large spinal epidural hematomas (SEHs), based on multilevel “skip hemilaminectomies.”
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Usefulness of oblique coronal CT and MRI imaging in the endoscopic endonasal approach to treat skull base lesions  Voir?

This report examines the utility of the preoperative image to orientate the surgeon in the sphenoid sinus during an endoscopic endonasal transsphenoidal approach (ETSS).
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Effect and Feasibility of Therapeutic Hypothermia in Patients with Hemorrhagic Stroke: A Systematic Review and Meta-Analysis  Voir?

Therapeutic hypothermia (TH) has shown good results in experimental models of hemorrhagic stroke. The clinical application of TH, however, remains controversial, since reports regarding its therapeutic effect are inconsistent.
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Endovascular patch embolization for blood blister–like aneurysms in the dorsal segment of the internal carotid artery  Voir?

Blood blister–like aneurysms (BBAs) in the dorsal segment of the internal carotid artery (ICA) are fragile and difficult to treat, and the optimal treatment for BBAs is still controversial. We report clinical and angiographic results with procedural details for the treatment of BBA by using the endovascular patch embolization method.

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Systematic review of factors influencing surgical performance: Practical recommendations for microsurgical procedures in neurosurgery  Voir?

Microneurosurgical techniques involve complex manual skills and hand-eye coordination that require substantial training. Many factors affect microneurosurgical skills. The goal of this study was to use a systematic evidence-based approach to analyze the quality of evidence for intrinsic and extrinsic factors that influence microneurosurgical performance and to make weighted practical recommendations.

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Histopathologic Analysis of Tamoxifen on Epidural Fibrosis  Voir?

Epidural fibrosis is a challenging topic in spinal surgery. This phenomenon constitutes one of the main reasons behind postlaminectomy syndrome or failed back surgery syndrome, which leads to persistent back and leg pain in association with compression and/or stretching the nerve root or the dura. The exact mechanism of action in epidural fibrosis is complex and remains uncertain. Excessive deposition of collagen, fibronectin, and dermatan sulfate, known as the “extracellular matrix,” and decrease of tissue cellularity results in epidural fibrosis.

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Surgical Anatomy of the Eustachian Tube for Endoscopic Transnasal Skull Base Surgery: A Cadaveric and Radiologic Study  Voir?

The endoscopic endonasal approach to the anatomically complex lateral skull base presents technical challenges. The use of the eustachian tube as a landmark to identify the petrous internal carotid artery has recently been reported, and this study aims to define the anatomic relationship between the eustachian tube and its surrounding structures using cadaveric dissection and radiologic analysis.

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Impact of Right-Sided Aneurysm, Rupture Status, and Size of Aneurysm on Perforator Infarction Following Microsurgical Clipping of Posterior Communicating Artery Aneurysms with a Distal Transsylvian Approach  Voir?

Posterior communicating artery (PCoA) aneurysms are among the most common aneurysms. Because blockage of the PCoA and perforators can cause adverse outcomes, occlusion of these arteries by surgical clipping should be avoided. The impact of factors on PCoA perforator infarction when using a distal transsylvian approach for PCoA aneurysms was examined.

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Novel Assessment of Cerebrospinal Fluid Dynamics by Time-Spatial Labeling Inversion Pulse Magnetic Resonance Imaging in Patients with Chiari Malformation Type I  Voir?

We investigated cerebrospinal fluid (CSF) dynamics at the craniocervical junction (CCJ) using Time-SLIP magnetic resonance imaging to demonstrate the significance of ventral and dorsal combined CSF dynamics in assessing CSF flow disturbance in patients with Chiari malformation type I.
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Physical Risk Factors of Hemorrhagic Complications Associated with Angio-Seal Closure Device Use in Neurointerventional Procedures  Voir?

Few studies have demonstrated detailed physical risk factors of hemorrhagic complications (HCs) associated with the Angio-Seal closure device. This retrospective study aimed to identify the risk factors of HC due to Angio-Seal use.
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Agreement Between Extent of Meningioma Resection Based on Surgical Simpson Grade and Based on Postoperative Magnetic Resonance Imaging Findings  Voir?

The surgical Simpson grade, introduced in 1957, is the standard measure for meningioma resection and prediction of recurrences. We used an magnetic resonance (MR)–based grading system for the radiologic extent of resection, and assessed agreement of the extent of resection between the surgical Simpson grade and the MR-based scale.

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Anterior Skull Base Tumor Resection by Transciliary Supraorbital Keyhole Craniotomy: A Single Institutional Experience  Voir?

The prognosis and recurrence rate after resection of an anterior skull base lesion via transciliary supraorbital keyhole craniotomy depend on residual tumor volume. The extent to which pathology and size of tumor influence the resection rate using this approach is unknown.
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Toward Shorter Hospitalization After Endoscopic Transsphenoidal Pituitary Surgery: Day-by-Day Analysis of Early Postoperative Complications and Interventions  Voir?

It is unclear which patients have the greatest risk of developing complications in the first days after endoscopic transsphenoidal pituitary surgery (ETS) and how long patients should stay hospitalized after surgery. The objective of this study is to identify which patients are at risk for early postoperative medical and surgical reinterventions to optimize the length of hospitalization.

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Clinical Features, Treatment, and Prognostic Factors of 56 Intracranial and Intraspinal Clear Cell Meningiomas  Voir?

Intracranial and intraspinal clear cell meningiomas (CCMs) are rarely reported because of their extremely low incidence, and the current understanding of CCM is poor. The purpose of this study was to analyze the incidence and the clinical, radiologic, pathologic, and prognostic features of intracranial and intraspinal CCMs.

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Lumbar Dorsal Root Ganglion Block as a Prognostic Tool Before Pulsed Radiofrequency: A Randomized, Prospective, and Comparative Study on Cost-Effectiveness  Voir?

In the study, we discuss the predictive value and cost-effectiveness of dorsal root ganglion (DRG) blocks before using dorsal root ganglion pulsed radiofrequency (DRG-PRF) in the treatment of low back pain.
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Spheno-Orbital Meningiomas Surgery: Multicenter Management Study for Complex Extensive Tumors  Voir?

Spheno-orbital meningiomas (SOMs) are complex tumors involving the sphenoid wing, the orbit, and sometimes the cavernous sinus with bone hyperostosis and sheet-like dural involvement. Optimal removal, proptosis cure, and visual preservation remain a challenge.
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Intraarticular Pulsed Radiofrequency to Treat Refractory Lumbar Facet Joint Pain in Patients with Low Back Pain  Voir?

Many treatment techniques have been used for refractory lumbar facet joint pain; however, their efficacy has been controversial. In this study, we investigated the clinical efficacy and safety of intra-articular pulsed radiofrequency for the treatment of refractory lumbar facet joint pain in patients with low back pain.

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Interdisciplinary Care Model Independently Decreases Use of Critical Care Services After Corrective Surgery for Adult Degenerative Scoliosis  Voir?

Interdisciplinary management of elderly patients requiring spine surgery has been shown to improve short- and long-term outcomes. The aim of this study was to determine whether an interdisciplinary team approach mitigates use of intensive care unit (ICU) resources.
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Autologous Bone Harvest in Anterior Cervical Spine Surgery: A Quantitative and Qualitative In Vitro Analysis of Cadaveric Tissue  Voir?

The cervical spine may be used as a harvesting site of local autograft material during anterior cervical discectomy and fusion procedures. We analyzed the quality and composition of bone grafts obtained from different parts of the cervical vertebrae in a cadaveric model.
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Management of Solitary Intracranial Metastases of Differentiated Thyroid Carcinoma: 11 Pathologically Confirmed Cases and Systematic Literature Review  Voir?

Solitary intracranial metastases of differentiated thyroid carcinoma (DTC) are rare, and their management is still controversial. This research aimed to seek suitable therapeutic methods for this disease.
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Biomechanical Role of the Thoracolumbar Ligaments of the Posterior Ligamentous Complex: A Finite Element Study  Voir?

To investigate the effect of sequential ligament failure on the range of motion (ROM) and location of the instantaneous axes of rotation (IAR) of the thoracolumbar spine (T12–L1) finite element (FE) model, and to verify the role of the supraspinous ligament (SSL) in maintaining the stability of the injured thoracolumbar spine.

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Microsurgical Treatment for Complex Basilar Artery Aneurysms with Long-Term Follow-Up in a Series of 35 Cases  Voir?

There has been a massive shift in the balance toward endovascular therapy for basilar artery (BA) aneurysms in the modern era.
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Early Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Infarction in Asian Patients: A Single-Center Study  Voir?

Early decompression craniectomy (within 48 hours of stroke onset) in acute and malignant middle cerebral artery (MCA) ischemic stroke (IS) reduces mortality and increases the proportion of patients with favorable functional outcome. Various cultural and social issues among Asians lead to some differences in clinical practice, especially when surgical interventions are involved. Accordingly, decompressive craniectomy in Asian patients with stroke is often delayed.

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How Should Syringomyelia be Defined and Diagnosed?  Voir?

Syringomyelia is considered as a fluid-filled cavitation inside the spinal cord. However, there is no agreement whether a dilated central canal should be included under this heading or how glioependymal cysts, myelomalacias, or cystic tumors should be distinguished from syringomyelia. This article provides a definition of syringomyelia and guidelines for its diagnosis.

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The Real impact of Intraoperative MRI in newly diagnosed Glioblastoma Multiforme Resection: an Observational Analytic Cohort study from a Single Surgeon Experience  Voir?

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Headache Resolution After Rathke Cleft Cyst Resection: A Meta-Analysis  Voir?

Rathke cleft cysts (RCC) are benign lesions of the sella that often present with headache. It is not currently well established whether surgical resection of RCC results in resolution of headache. We conducted a meta-analysis to examine the effect of RCC resection on headache resolution.
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Three-Dimensional Printed Skull Base Simulation for Transnasal Endoscopic Surgical Training  Voir?

Transnasal endoscopic skull base surgery (SBS) presents a major challenge for inexperienced neurosurgeons because of the complicated anatomic structures, 2-dimensional endoscopic view, limited operative field, and required skills. We designed a personalized multimaterial and multicolor three-dimensional (3D)-printed SBS simulation to reproduce the complex anatomy of the skull base. The fidelity and feasibility for anatomic education and surgical training were assessed.

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Digital Polymerase Chain Reaction Quantification of SERPINA1 Predicts Prognosis in High-Grade Glioma  Voir?

SERPINA1 plays an anti-inflammatory role in protecting tissues from proteolytic mechanisms. SERPINA1 is positive in gliomas by immunohistochemical analysis; however, the role of SERPINA1, including the relationship with prognosis, has been uncertain. In recent years, digital polymerase chain reaction (PCR) has provided ultra-sensitive assessment of messenger RNA expression from formalin-fixed paraffin-embedded (FFPE) tissues.

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Interaction Between the Contributions of Tumor Location, Tumor Grade, and Patient Age to the Survival Benefit Associated with Gross Total Resection  Voir?

Gross total resection (GTR) in patients with glioblastoma (GB) and anaplastic astrocytoma (AA) is associated with improved survival. We examined how tumor location, tumor grade, and age affected this benefit.
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Usefulness and Stability of Intraoperative Digital Subtraction Angiography Using the Transradial Route in Arteriovenous Malformation Surgery  Voir?

Digital subtraction angiography is the gold standard to confirm complete removal of an arteriovenous malformation (AVM) nidus. However, the transfemoral approach requires specialized instrumentation and is cumbersome and difficult to perform with the patient in the prone or decubitus position. We report the use of intraoperative digital subtraction angiography (iDSA) with the transradial approach and examine its usefulness and safety.

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Loss of Subcortical Language Pathways Correlates with Surgery-Related Aphasia in Patients with Brain Tumor: An Investigation via Repetitive Navigated Transcranial Magnetic Stimulation–Based Diffusion Tensor Imaging Fiber Tracking  Voir?

Within language function research, there is a shift of focus from cortical specialization to a more hodotopical view including subcortical fiber tracts in functional and oncologic considerations. Diffusion tensor imaging fiber tracking (DTI FT) is well established to visualize subcortical fiber tracts. Recently, a new technique has been developed using cortical regions mapped via repetitive navigated transcranial magnetic stimulation (rTMS) as seed regions. This study investigates if rTMS-based DTI FT for language pathways is also feasible postoperatively and whether preoperative versus postoperative fiber changes correlate with changes and severity of the patients' aphasia grades.

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Microsurgical and Endovascular Treatments of Spinal Extradural Arteriovenous Fistulas with or without Intradural Venous Drainage  Voir?

To present treatment strategies for spinal extradural arteriovenous fistulas (AVFs) in relation to angioarchitecture.
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Anterior versus Posterior Selective Fusion in Treating Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-Analysis of Radiologic Parameters  Voir?

To compare the clinical efficacy of anterior and posterior approaches for selective thoracic fusion (STF) and selective thoracolumbar/lumbar fusion (SLF) in treating adolescent idiopathic scoliosis (AIS).
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Surgical Treatment of Spinal Ependymomas: Experience in 49 Patients  Voir?

Ependymomas are rare central nervous system tumors. Local tumor distribution in the central nervous system depends on age: among adults, ependymomas occur mostly in the spinal cord, whereas among children, intracranial manifestations are more common. To date, there are no prospective studies about treatment strategies for ependymomas. In most cases, complete tumor resection is recommended. The role of radiation therapy in low-grade ependymomas is unclear.

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Salvage Anterior Lumbar Interbody Fusion for Pseudoarthrosis After Posterior or Transforaminal Lumbar Interbody Fusion: A Review of 10 Patients  Voir?

After interbody cage implantation for posterior or transforaminal lumbar interbody fusion (PLIF or TLIF) spinal fusion surgery, pseudoarthrosis can develop. However, there are several shortcomings of the posterior approach if the interbody cage requires removal. Therefore, an anterior approach may be useful.

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Epidural Fluid Collection After Percutaneous Endoscopic Lumbar Discectomy  Voir?

The frequency and extent of epidural fluid collection after percutaneous endoscopic lumbar discectomy (PELD) have not been previously described. The purpose of this study was to evaluate the significance of epidural fluid collection after PELD.
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Comparison of Monitoring of Cerebral Blood Flow by c-FLOW and Transcranial Doppler in Carotid Endarterectomy  Voir?

To prospectively compare the use of the cerebral blood flow monitor (c-FLOW) and transcranial Doppler (TCD) as 2 techniques for assessing brain perfusion during carotid endarterectomy.
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Intraventricular Hemorrhage Caused by Subarachnoid Hemorrhage: Does the Severity Matter?  Voir?

Aneurysm rupture might be accompanied by intraventricular hemorrhage (IVH), which is associated with poor outcome of subarachnoid hemorrhage (SAH). The aim of this study was to analyze risk factors and clinical impact of IVH severity.
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Endoscope Holders in Cranial Neurosurgery: Part 2—An International Survey  Voir?

Following a previous systematic review of currently available endoscope holders (EHs), we aspired to detect trends, task-specific preferences, and pitfalls of EH in various cranial neuroendoscopic procedures.
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Effect of Pulsed Radiofrequency Treatment on the Thoracic Medial Branch for Managing Chronic Thoracic Facet Joint Pain Refractory to Medial Branch Block with Local Anesthetics  Voir?

To evaluate the effect of pulsed radiofrequency (PRF) stimulation of the thoracic medial branch of the dorsal ramus in patients with chronic thoracic facet joint (TFJ) pain who were refractory to medial branch block (MBB).
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Top-100 Highest-Cited Original Articles in Ischemic Stroke: A Bibliometric Analysis  Voir?

The total number of citations of a research article can be used to determine its impact on the scientific community. We aimed to identify the top-100 articles published on ischemic stroke and evaluate their characteristics.
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High Incidence of Deep Vein Thrombosis in the Perioperative Period of Neurosurgical Patients  Voir?

A prospective study was designed to elucidate incidence and predictors of deep venous thrombosis (DVT) in patients undergoing craniotomies.
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Transradial Stenting for Carotid Stenosis in Patients with Bovine Type and Type III Aortic Arch: Experience in 28 Patients  Voir?

The effects and safety of transradial access for stenting of carotid artery stenosis in patients with bovine-type and type III aortic arch are currently unknown and are the purpose of this study.
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Atlantoaxial Fixation for Chiari 1 Formation in Pediatric Age-Group Patients: Report of Treatment in 33 Patients  Voir?

The role of atlantoaxial instability in the pathogenesis of Chiari 1 formation (Chiari formation) in pediatric age-group patients is evaluated.
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Morphometric MRI Imaging Study of the Corridor for the Oblique Lumbar Interbody Fusion Technique at L1-L5  Voir?

Anterior lumbar interbody fusion and lateral lumbar interbody fusion are associated with approach-related disadvantages. Oblique lumbar interbody fusion (OLIF) is the proposed solution, especially for upper lumbar levels. We analyzed the size and regional anatomy of the corridor used in the OLIF technique between levels L1 and L5.

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Prevalence of Petrosquamosal Sinus and Its Clinical Significance: Radiologic Study and Meta-analysis  Voir?

The petrosquamosal sinus (PSS) is clinically important as it represents a potential hemorrhagic hazard during neurosurgical procedures. This double-approach radiologic study and meta-analysis aimed to assess the imaging characteristics of the PSS on computed tomography (CT) and systematically analyze its prevalence to improve imaging accuracy and assist in neurosurgical management.

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Trends of Platelet Volume Index Predicts Delayed Cerebral Ischemia After Subarachnoid Hemorrhage  Voir?

Delayed cerebral ischemia (DCI) is a major cause of disability after aneurysmal subarachnoid hemorrhage (aSAH). Activated platelets are surrogate markers for DCI occurrence and are reliably represented by mean platelet volume (MPV) to platelet count (PLT) ratio. If validated as a predictor of DCI, the ratio will allow clinicians to use it as a readily available tool in patient management.

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Comparing Uniplanar and Multiaxial Pedicle Screws in the Derotation of Apical Vertebrae for Lenke V Adolescent Idiopathic Scoliosis: A Case-Controlled Study  Voir?

To compare effects of uniplanar and multiaxial pedicle screws on apical vertebral derotation efficiency in patients with Lenke V adolescent idiopathic scoliosis.
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Differentiating Optic Meningioma from Cavernous Hemangioma Using Multiparametric Magnetic Resonance Imaging  Voir?

Thank you for your excellent remarks about surgical management of orbital masses associated with rapid vision loss, where excision must be performed. In the case of an apical mass compressing the optic nerve, surgery must also be considered urgent.
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Biomechanical Analysis of Porous Additive Manufactured Cages for Lateral Lumbar Interbody Fusion: A Finite Element Analysis  Voir?

A porous additive manufactured (AM) cage may provide stability similar to that of traditional solid cages and may be beneficial to bone ingrowth. The biomechanical influence of various porous cages on stability, subsidence, stresses in cage, and facet contact force has not been fully described. The purpose of this study was to verify biomechanical effects of porous AM cages.

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An Integrative Survival Analysis with Identification of Prognostic Factors in the Patients with Coexisting Glioma and Intracranial Aneurysm  Voir?

This study aimed to perform an integrative clinical and survival analysis for patients with coexisting glioma and intracranial aneurysm and to assess the influence of prognostic factors on overall survival (OS).
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In Reply  Voir?

We thank the commenter(s) for his/her/their very professional comments regarding our recent paper.1 We appreciate the careful review and valuable suggestions on the further research of the Gamma Knife Surgery (GKS) effect on World Health Organization grade II meningiomas. We would like to respond to the comments.

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Evaluation of Patient Perspectives Toward Awake, Frame-Based Deep-Brain Stimulation Surgery  Voir?

Deep brain stimulation (DBS) is an effective therapeutic modality; however, only a percentage of eligible patients undergo the procedure.
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Surgical Revascularization for the Treatment of Complex Anterior Cerebral Artery Aneurysms: Experience and Illustrative Review  Voir?

Many methods for treating complex anterior cerebral artery (ACA) aneurysms are available; however, there is substantial variation among methods because of various aneurysm locations, the relationship of the aneurysm to arterial branches, aneurysm size and other morphologic characteristics, and the diameters of the parent or branching arteries.

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Flat Posterior Cranial Fossa Affects Outcomes of Microvascular Decompression for Trigeminal Neuralgia  Voir?

To investigate the prognostic factors for microvascular decompression (MVD) in patients with primary trigeminal neuralgia (TN), with a particular focus on the morphology of the posterior cranial fossa (PCF).
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Risk Factors and Management of Dural Defects in Anterior Surgery for Cervical Ossification of the Posterior Longitudinal Ligament  Voir?

To investigate risk factors and outcomes and to develop a cogent perioperative management algorithm for dural defects (DDs) in anterior surgery for cervical ossification of the posterior longitudinal ligament (OPLL).
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Association Between IDH1 and IDH2 Mutations and Preoperative Seizures in Patients with Low-Grade Versus High-Grade Glioma: A Systematic Review and Meta-Analysis  Voir?

Patients with brain tumors, particularly gliomas, commonly present with seizures. Higher incidence of seizure has been reported in low-grade gliomas and tumors located within the temporal and insular area. The association between IDH1 and IDH2 mutations with preoperative seizures in glioma and the magnitude of this association in low-grade versus high-grade gliomas are unclear. To clarify this relationship, a systematic review and meta-analysis was performed.

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Risk Factors Associated with Meningitis after Neurosurgery: A Retrospective Cohort Study in a Chinese Hospital  Voir?

Meningitis is a serious complication occurring after neurosurgical operations, which can result in severe morbidity and high mortality. This retrospective cohort study aimed to determine the risk factors of postoperative meningitis in a large clinical center of neurosurgery in China.
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Variability in Surgical Treatment of Spondylolisthesis Among Spine Surgeons  Voir?

There are a multitude of treatments for low-grade lumbar spondylolisthesis. There are no clear guidelines for the optimal approach.
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Decision Making for the Surgical Treatment of Vertebral Metastases Among Patients with Short Predicted Survival  Voir?

A wide spectrum of treatment choices is proposed for poor-prognosis patients with vertebral metastases. The continuous increase of this population and the propagation of less invasive techniques necessitate further study concerning which patients could benefit from palliative surgery.
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Risk Factors for Unfavorable Outcomes in Surgically Treated Brainstem Cavernous Malformations  Voir?

Brainstem cavernous malformations (BSCMs) account for up to 18% of all intracranial cavernous malformations. Due to their complex anatomic location, they represent a significant challenge for neurosurgeons. As such, the identification of risk factors associated with negative outcomes is of significant importance. We analyze a series of 50 cases of BSCMs treated surgically in order to identify risk factors for unfavorable outcomes.

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Cerebral Radiation Necrosis: An Analysis of Clinical and Quantitative Imaging and Volumetric Features  Voir?

Radiation therapy is an effective treatment for primary brain tumors and intracranial metastases but can occasionally precede new enhancing lesions on imaging studies that are difficult to discern between tumor recurrence (TR) and radiation necrosis (RN). The aim of this study was to identify clinical presentation and imaging patterns of RN compared with TR that may obviate the need for invasive definitive biopsy.

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Pituitary Apoplexy: Should Endoscopic Surgery Be the Gold Standard?  Voir?

Pituitary apoplexy is an uncommon, potentially fatal condition due to spontaneous ischemia or hemorrhage in a pituitary adenoma. The treatment of this disorder has long been a matter of debate.
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Memory Deficits After Aneurysmal Subarachnoid Hemorrhage: A Functional Magnetic Resonance Imaging Study  Voir?

Patients who have sustained aneurysmal subarachnoid hemorrhage (aSAH) are thought to have cognitive impairment. However, little is known about the characteristics of functional imaging in patients with aSAH. In this study, we explored whole brain activity patterns in patients with aSAH using amplitude of low-frequency fluctuation (ALFF) and functional connectivity (FC).

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Sexual Dysfunction After Good-Grade Aneurysmal Subarachnoid Hemorrhage  Voir?

To assess the consequences of aneurysmal subarachnoid hemorrhage (aSAH) on sexual pleasure in patients with an otherwise favorable neurologic outcome.
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The Top 50 Most-Cited Articles on Acoustic Neuroma  Voir?

Acoustic neuroma is the most common extra-axial primary cerebellopontine angle tumor in adults. A plethora of studies have been published on acoustic neuroma, but none of the previous works have highlighted the most influential articles. Our objective was to perform a bibliometric analysis of the 50 most-cited articles on acoustic neuroma.

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Corrigendum to “Coma and Stroke Following Surgical Treatment of Unruptured Intracranial Aneurysm: An American College of Surgeons National Surgical Quality Improvement Program Study” [World Neurosurgery (2016) 91:272–278]  Voir?

The authors regret that during post-submission review of our accepted manuscript, we discovered that the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) Participant User File issued a data update reporting a coding error for the postoperative coma outcome variable from 2011 onward. For this reason, we repeated our analysis excluding those patients who developed coma alone (n=3). Overall, the results remained the same. As such, we believe that the validity of our study is not threatened after excluding the inaccurate coma cases.

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The Use of Flow Diverter in Ruptured, Dissecting Intracranial Aneurysms of the Posterior Circulation  Voir?

Acute dissecting aneurysms of the posterior circulation are a rare cause of subarachnoid hemorrhage. Established endovascular treatment options include parent artery occlusion and stent-assisted coiling, but appear to be associated with an increased risk of ischemic stroke. Vessel reconstruction with flow diverters is an alternative treatment option; however, its safety and efficacy in the acute stage remains unclear.

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Sport-Related Traumatic Brain Injury with and without Helmets in Children  Voir?

Soccer, bicycling, and horseback riding are sports most commonly associated with traumatic brain injury (TBI) in Germany. The latter 2 sports activities are commonly practiced with helmets, and data on helmet use and usefulness vary widely.
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Colloid Cyst of the Third Ventricle: Long-Term Results of Endoscopic Management in a Series of 112 Cases  Voir?

The endoscopic approach increasingly is used to treat third ventricular colloid cysts. Our objective was to assess the results of endoscopic resection of colloid cysts of the third ventricle.
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Feasibility of a Modified E-PASS and POSSUM System for Postoperative Risk Assessment in Patients with Spinal Disease  Voir?

This retrospective case control study aimed to evaluate the feasibility of using Estimation of Physiological Ability and Surgical Stress (E-PASS) and Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity (POSSUM) systems in patients undergoing spinal surgical procedures. Degenerative spine disease has increased in incidence in aging societies, as has the number of older adult patients undergoing spinal surgery. Many older adults are at a high surgical risk because of comorbidity and poor general health.

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Smartphone Usage Patterns by Canadian Neurosurgery Residents: A National Cross-Sectional Survey  Voir?

Smartphones and their apps are used ubiquitously in medical practice. However, in some cases their use can be at odds with current patient data safety regulations such as Canada's Personal Health Information Protection Act of 2004. To assess current practices and inform mobile application development, we sought to better understand mobile device usage patterns among Canadian neurosurgery residents.

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Long-Term Follow-Up Comparative Study of Hydroxyapatite and Autologous Cranioplasties: Complications, Cosmetic Results, Osseointegration  Voir?

A three-dimensional reconstruction technique using the CustomBone (CB) prosthesis allows custom-made cranioplasty (CP) possessing osseointegration properties owing to its porous hydroxyapatite (HA) composition. This reconstruction technique has replaced less expensive techniques such as subcutaneously preserved autologous bone (SP). Our primary objective was to evaluate complications between CB and SP CP techniques. A secondary objective was to assess cosmetic results and osseointegration of CPs.

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Gadobutrol and the End of the Tap Test  Voir?

Normal pressure hydrocephalus (NPH) is a neurologic syndrome characterized by a triad of clinical symptoms consisting of gait apraxia, dementia, and urinary incontinence associated with ventriculomegaly (radiologically detected) and normal cerebrospinal fluid (CSF) pressure.1 Treatment of NPH is mainly aimed at restoring the patient's functional capacity. In this way, the decision about when a surgical intervention should be carried out requires that the probability of such restoration be taken into account through the use of some tools that predict the postoperative result.

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It's Not Just Time; Imaging Is Brain, Too: The DAWN Trial and Changing Definition of the Therapeutic Window for Acute Ischemic Stroke  Voir?

The benefit of immediate recanalization of an occluded large intracranial artery in the anterior circulation (internal carotid artery, middle cerebral artery) by endovascular mechanical thrombectomy was conclusively established by several pivotal multicenter randomized trials published more than 2 years ago.1 The recommended therapeutic window is 6 hours from symptom onset (last known normal or time last seen well). According to the 2015 American Heart Association/American Stroke Association, most studies have recruited patients within this time frame and the ones that recruited patients up to 8 and 12 hours (ESCAPE, REVASCAT) have had insufficient numbers to derive firm conclusions.

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Instrumented Spinal Stabilization without Fusion for Spinal Metastatic Disease  Voir?

Spinal stabilization surgery is an integral part of the treatment of spinal metastatic disease. Bony fusion is the hallmark of spinal stabilization in non-oncology patients. Spinal oncology patients are unlikely to achieve bony fusion because of their overall prognosis and concurrent therapies. Stabilization surgery without fusion may be a reasonable approach for these patients. Literature evaluating the effectiveness of this approach is limited. The object of this study was to investigate the rate of instrumentation failure in patients undergoing posterior spinal instrumented stabilization without fusion for spinal metastatic disease.

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Visualization of Needle-Tip Localization by Ultrasound Guidance with Contrast Bubble in Lumbar Selective Nerve Root Block: Clinical Pilot Study  Voir?

Epidural steroid injection for low back and leg pain has been shown to result in a positive clinical outcome. Lumbosacral selective nerve root block (SNRB) via a transforaminal approach is commonly performed under fluoroscopic guidance. However, ultrasound guidance is an alternative to overcome the radiologic disadvantages. This study examined the accuracy of needle-tip localization under ultrasound guidance with a contrast bubble, compared with fluoroscopic guidance.

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Acute Effects of Electrical Stimulation of the Bed Nucleus of the Stria Terminalis/Internal Capsule in Obsessive-Compulsive Disorder  Voir?

Deep brain stimulation (DBS) has been introduced as a treatment option for treatment-resistant obsessive-compulsive disorder (OCD). However, the optimal stimulation target and the corresponding stimulation settings remain unclear. Furthermore, there is limited knowledge about the acute effects of DBS.

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Comparative Cohort Study of Percutaneous Pedicle Screw Implantation without Versus with Navigation in Patients Undergoing Surgery for Degenerative Lumbar Disc Disease  Voir?

The major limitation of computer-based three-dimensional fluoroscopy is increased radiation exposure of patients and operating room staff. Combining spine navigation with intraoperative three-dimensional fluoroscopy (io3DF) can likely overcome this shortcoming, while increasing pedicle screw accuracy rate. We compared data from a cohort of patients undergoing lumbar percutaneous pedicle screw placement using io3DF alone or in combination with spine navigation.

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Proton Magnetic Resonance Spectroscopy Detection of High Lipid Levels and Low Apparent Diffusion Coefficient Is Characteristic of Germinomas  Voir?

The differentiation of germinoma from other tumors by conventional magnetic resonance imaging (MRI) can be very difficult. The purpose of our study was to determine whether diffusion-weighted imaging (DWI) and single-voxel proton magnetic resonance spectroscopy (1H-MRS) could provide additional useful information for a definitive diagnosis of germinomas.

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The Prevalence of Cerebrovascular Abnormalities Detected in Various Diagnostic Subgroups of Spontaneous Subarachnoid Hemorrhage in the Modern Era  Voir?

To determine prevalence of cerebrovascular abnormalities in diagnostic subgroups of spontaneous subarachnoid hemorrhage (SAH) in a regional neurosurgical center in the modern era.
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Does Obesity Affect Perioperative and Postoperative Morbidity and Complication Rates After Minimal Access Spinal Technologies in Surgery for Lumbar Degenerative Disc Disease  Voir?

The impact of obesity on spine surgery has been studied extensively, but only a few investigations have been focused on minimally invasive spinal fusion techniques and complication rates in normal-weight, preobese, or obese patients. Obesity was found to be a risk factor for intraoperative complications. Published data tend to favor minimal access surgery techniques (MAST) for obese patients. In a prospective study, we assessed the perioperative and postoperative complications of MAST in a large population of 187 patients.

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Risk Factor Analysis for Poor Outcomes in Supraorbital Keyhole Aneurysm Clipping for Ruptured Anterior Circulation Aneurysms  Voir?

The transciliary keyhole approach has been actively employed for unruptured intracranial aneurysms in many institutions, although applying this technique to ruptured aneurysms remains controversial. We investigated risk factors related to poor surgical outcomes in ruptured aneurysms and attempted to clarify the differences between conventional craniotomy and keyhole surgery.

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Levels of Interleukin-1β, Interleukin-18, and Tumor Necrosis Factor-α in Cerebrospinal Fluid of Aneurysmal Subarachnoid Hemorrhage Patients May Be Predictors of Early Brain Injury and Clinical Prognosis  Voir?

Aneurysmal subarachnoid hemorrhage (aSAH) is a severe cerebrovascular accident with high morbidity and mortality. The aim of this study is to investigate the relationship between level of inflammatory cytokines in cerebrospinal fluid (CSF) of aSAH patients, the severity of aSAH, and the outcome of aSAH patients.

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Infection Rate after Cranial Neurosurgical Procedures: A Prospective Single-Center Study  Voir?

To determine infection rate (IR) and to identify modifiable risk factors (RF) in cranial neurosurgery in a neurosurgical department for tertiary referral as part of an infection control surveillance to reduce surgical site infections (SSI).
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Carotid–Carotid Artery Crossover Bypass with a Synthetic Vascular Graft for Symptomatic Type 1A Common Carotid Artery Occlusion  Voir?

To investigate the effect of carotid–carotid artery crossover bypass with a synthetic vascular graft for symptomatic type 1A common carotid artery occlusion (CCAO).
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Multimodal Treatment of Intracranial Aneurysms in Children: Clinical Case Series and Review of the Literature  Voir?

The management of intracranial aneurysms in the pediatric population presents unique challenges. Cases are rare and tend to be of higher complexity compared with aneurysms in adults. Outcomes in long-term follow-up are not well-characterized. Here we present illustrative case examples to demonstrate key concepts in managing these lesions in the context of the modern neurovascular era.

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In Reply to “A Reply to Commentaries to: Surgical and Medical Mission to Mongolia: Experience and Lessons”  Voir?

We offer several additional comments based on the authors' response to several Perspectives on their original article.1,2 We would also like to note that the Virtue Foundation has been returning to Mongolia for “Surgical and Teaching Missions” for 9 years, although the neurosurgery program did not start until 2014.3 The other specialties include ophthalmology, ear-nose-throat, oral-maxillofacial surgery, anesthesiology, hepatobiliary surgery, and microvascular surgery.

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Computed Tomography Evaluation of the Correspondence Between the Arcuate Eminence and the Superior Semicircular Canal  Voir?

The arcuate eminence (AE) has been traditionally used in middle cranial fossa (MCF) surgery as a guide to accurate location of the superior semicircular canal (SSC) deep within the temporal bone. However, the anatomic relationship between the AE and SSC is controversial. We evaluated the anatomic coincidence between the AE and the SSC in the MCF surface. Distances between the most relevant anatomic structures in the MCF and prevalence of SSC dehiscence were measured.

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Rupture Risk of Cerebral Arteriovenous Malformations During Pregnancy and Puerperium: A Single-Center Experience and Pooled Data Analysis  Voir?

Whether rupture risk of cerebral arteriovenous malformation (AVM) is higher during pregnancy and puerperium remains controversial. This study aimed to compare risk of rupture in pregnant and nonpregnant female patients with AVM in a singer-center series and assess current evidence regarding rupture risk of AVM during pregnancy and puerperium by pooled data analysis.

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Lentivirus Is an Efficient and Stable Transduction Vector for Intervertebral Disc Cells  Voir?

To evaluate transduction efficacy and sustainability of lentiviral vector for intervertebral disc cells both in vitro and in vivo.
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Management of Isolated Atlas Fractures: A Retrospective Study of 65 Patients  Voir?

Jefferson fractures, or burst fractures of the C1 vertebra, can be managed surgically or conservatively, depending on their stability.
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Survival of Ventricular and Periventricular High-Grade Gliomas: A Surveillance, Epidemiology, and End Results Program–Based Study  Voir?

Aggressiveness of surgical resection for periventricular/ventricular high-grade gliomas (HGGs) is determined by operative risks and assumed effectiveness of radiation therapy (RT) on residual tumor. We aimed to clarify the impact of surgery and postoperative RT on patient survival in a population-based study.

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Prospective Study of Neuroendoscopy versus Microscopy: 213 Cases of Microvascular Decompression for Trigeminal Neuralgia Performed by One Neurosurgeon  Voir?

To compare the efficacy and complications of microvascular decompression (MVD) by complete neuroendoscopy versus microscopy for 213 cases of trigeminal neuralgia (TN).
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Retrosigmoid Approach: Investigating the Role of a C-Shaped Skin Incision and Muscle Flaps in Improving Functional Outcome and Reducing Postoperative Pain  Voir?

To investigate the impact on functional outcome and postoperative pain of a modified C-shaped skin incision and muscle flaps in patients undergoing mini-craniotomy via a retrosigmoid approach (mCRSA).
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Predictors of Occurrence and Anatomic Distribution of Multiple Aneurysms in Patients with Aneurysmal Subarachnoid Hemorrhage  Voir?

The literature on multiple intracranial aneurysms (MIA) in patients with aneurysmal subarachnoid hemorrhage (aSAH) focuses largely on risk factor analysis and consists essentially of retrospective cohort studies of limited sample size, or studies in populations outside Europe and North America. The purpose of this cohort study was to identify predictors for aneurysm multiplicity and to investigate the anatomic distribution of MIA in a representative Western cohort of patients with aSAH.

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Delayed coil migration after treatment of traumatic pseudoaneurysm  Voir?

A teenager with epistaxis after head trauma was diagnosed with pseudoaneurysm of internal carotid artery. Three years after the first aneurysm embolization, delayed coil migration was detected. Then the migrated coil was removed through nasal-endoscopy.
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The Utility of Early Postoperative Head Computed Tomography in Brain Tumor Surgery: A Retrospective Analysis of 755 Cases  Voir?

Scheduled early postoperative computed tomography (EPOCT) after craniotomy for brain tumor resection is standard at many institutions. We analyzed utility of preplanned EPOCT after elective craniotomy for brain tumor resection.
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A Novel Method to Measure the Tentorial Angle and the Implications on Surgeries of the Pineal Region  Voir?

There is no standard way to define the angle of the tentorium. The current trend to use the Twining line to define this angle has significant pitfalls. The goal of the current study was to provide a new and accurate way to measure the tentorial angle and demonstrate its impact on surgeries of the pineal region.

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Utility of Intracranial Pressure Monitoring for Diagnosis of Idiopathic Intracranial Hypertension in the Absence of Papilledema  Voir?

Idiopathic intracranial hypertension (IIH) is characterized by headaches, visual obscurations, and papilledema, and the diagnosis involves lumbar puncture (LP) with an elevated opening pressure (OP) ≥20 cm H20. When papilledema is absent, the diagnosis becomes less clear. Some physicians have argued that the absence of papilledema rules out IIH, whereas others maintain that elevated OP is sufficient for diagnosis.

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Differential Tumor Progression Patterns in Skull Base Versus Non–Skull Base Meningiomas: A Critical Analysis from a Long-Term Follow-Up Study and Review of Literature  Voir?

To analyze the differences in tumor progression patterns and histopathologic characteristics between skull base meningiomas (SBMs) and non–skull base meningiomas (NSBMs).
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Outcome of Traumatic Brain Injury in the Elderly Population: A Tertiary Center Experience in a Developing Country  Voir?

The growing elderly population has contributed to an increasing incidence of traumatic brain injury (TBI) in this cohort worldwide. Here we describe our institutional experience in the management of TBI in elderly Indian patients.
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Comparison of Single-Level and Multilevel Decompressive Laminectomy for Multilevel Lumbar Spinal Stenosis  Voir?

This study aimed to clarify whether multiple compressions of nerve roots resulted in poorer surgical outcome when patients were treated with single-level decompressive laminectomy or multilevel decompressive laminectomy. To reach this we compared preoperative and postoperative Oswestry Disability Index (ODI) scores, Visual Analogue Scale (VAS) scores, and walking duration of multilevel lumbar spinal stenosis (LSS) patients treated with single-level and multilevel decompressive laminectomy.

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Early Postoperative Magnetic Resonance Imaging Findings After Percutaneous Endoscopic Lumbar Discectomy and Their Correlations with Clinical Outcomes  Voir?

To investigate the imaging features on early postoperative magnetic resonance imaging (MRI) after percutaneous endoscopic lumbar discectomy (PELD) and their correlations with surgical outcomes.
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Impacts of a Size Ratio on Outcome in Patients with Surgically Treated Unruptured Nondissecting Anterior Cerebral Artery Aneurysms  Voir?

Anterior cerebral artery aneurysms (ACAs) are characterized by higher rupture rate and small size at rupture. It was shown that the aneurysm/vessel size ratio, and not the absolute size, might predict the risk of rupture in small unruptured intracranial aneurysms.The present study aimed to investigate the relationship between a size ratio and outcome in patients with unruptured nondissecting ACA aneurysms (UNDAs).

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Predictive Value of Intraoperative Facial Motor Evoked Potentials in Vestibular Schwannoma Surgery Under 2 Anesthesia Protocols  Voir?

We sought to validate the feasibility of facial motor evoked potential (FMEP) in facial nerve (FN) monitoring during vestibular schwannoma (VS) surgery under 2 anesthesia protocols and to examine its value for postoperative prognosis.
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MyD88 Mutation in Elderly Predicts Poor Prognosis in Primary Central Nervous System Lymphoma: Multi-Institutional Analysis  Voir?

Recent genetic analysis of primary central nervous system lymphoma (PCNSL) showed that the MyD88 L265P mutation, which is related to NF-κB signaling, was a genetic hallmark for PCNSL; thus it could serve as a genetic marker for diagnosis and a potential target for molecular therapy. However, the role of the MyD88 mutation in PCNSL has not been defined. In this study, we investigated the role of the MyD88 mutation and clinical features of PCNSL-treated patients at several institutions to determine its significance as a prognostic factor.

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Effect of Epineurial Neurorrhaphy on Restoration of Facial Nerve Injuries with Different Levels of Neurotmesis in a Rat Model: A Pilot Study  Voir?

Different degrees of neurotmesis of the peripheral facial nerve frequently are encountered in clinic, for which the epineurial neurorrhaphy is the preferred technique. However, because of the capability of self-restoration of nerves and the side effects of surgery, neurorrhaphy may not be an optimal choice for various degrees of neurotmesis. In this study, we explored the necessity of epineurial neurorrhaphy for different degrees of neurotmesis, in addition to investigating factors that impact neural functional recovery.

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Use of Tubular Retractor for Resection of Deep-Seated Cerebral Tumors and Colloid Cysts: Single Surgeon Experience and Review of the Literature  Voir?

Brain retraction is often required to develop a surgical corridor during the resection of deep-seated intracranial lesions. Traditional blade retractors distribute pressure asymmetrically and may case local tissue damage. Tubular retractors minimize this pitfall by distributing pressure evenly, which has been shown to translate to significant safety and efficacy data. Further qualified reports regarding the use of tubular retractors are of interest.

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Effectiveness of Transpedicular Dynamic Stabilization in Treating Discogenic Low Back Pain  Voir?

To assess clinical outcomes after dynamic stabilization in discogenic low back pain.
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Role of Visuohaptic Surgical Training Simulator in Resident Education of Orthopedic Surgery  Voir?

We sought to assess the validity of a virtual surgical training system on lumbar pedicle screw placement for residents.
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Effect positive end-expiratory pressure (PEEP) on risk of postoperative pulmonary complications in patients undergoing elective craniotomy  Voir?

Intraoperative use of positive end-expiratory pressure (PEEP) has a protective effect in patients with acute lung injury and is recommended during anesthesia to minimize postoperative pulmonary complications. However, high levels of pressure might also cause harm to the lung due to over distension. This retrospective study was designed to compare the effect of low and high levels of PEEP on the risk of postoperative pulmonary complications in patients with normal lung function undergoing an elective craniotomy.

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Opioid Prescribing Practices of Neurosurgeons: Analysis of Medicare Part D  Voir?

The Centers for Disease Control have declared that the United States is amidst a continuing opioid epidemic, with drug overdose−related death tripling between 1999 and 2014. Among the 47,055 overdose-related deaths that occurred in 2014, 28,647 (60.9%) of them involved an opioid.
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Delayed Postoperative Neurologic Deficit After Spine Deformity Surgery: Analysis of 5377 Cases at 1 Institution  Voir?

To our knowledge, few studies have focused on delayed postoperative neurologic deficit (DPND) after spine deformity surgery.
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Traumatic and Nontraumatic Spinal Cord Injuries  Voir?

Owing to the aging of the population in the United States, it is anticipated that injury mechanisms, treatment, and outcomes of spinal cord injuries (SCI) will change. There is a scarcity of literature on nontraumatic SCI. Our goal in this study was to evaluate the causes, management, complications, and outcomes after SCI.

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Radiologic Factors Predicting Deterioration of Mental Status in Patients with Acute Traumatic Subdural Hematoma  Voir?

To evaluate whether subdural hematoma (SDH) volume and other radiologic factors predict deterioration of mental status in patients with acute traumatic SDH.
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Drivers of Cervical Deformity Have a Strong Influence on Achieving Optimal Radiographic and Clinical Outcomes at 1 year Following Cervical Deformity Surgery  Voir?

The primary driver (PD) of cervical malalignment is important in characterizing cervical deformity(CD) and should be included in fusion to achieve alignment and quality-of-life goals. This study aims to define how PDs improve understanding of the mechanisms of cervical deformity, and assesses the impact of driver region on re-alignment/outcomes.

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Atlantoaxial Joint Distraction for the Treatment of Basilar Invagination: Clinical Outcomes and Radiographic Evaluation  Voir?

To investigate the causes of partial remission in patients with basilar invagination (BI) and irreducible atlantoaxial dislocation (IAAD) treated with transoral atlantoaxial reduction plate (TARP) without odontoidectomy and quantify the distance of odontoid descent.
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Presenting Symptoms and Prognostic Factors for Symptomatic Outcomes Following Resection of Meningioma  Voir?

Meningioma is the most common primary intracranial tumor and patients present with diverse neurologic symptoms related to meningioma location. This study aimed to systematically quantify the presenting symptoms of meningioma and identify prognostic factors for symptomatic outcome following resection.

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Decompression Alone Versus Decompression and Fusion for Lumbar Degenerative Spondylolisthesis: A Meta-Analysis  Voir?

To compare the effectiveness and safety of decompression alone (D group) with decompression and fusion (DF group) for patients who were diagnosed with lumbar degenerative spondylolisthesis (LDS).
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Correlation of Lactate Concentration in Peripheral Plasma and Cerebrospinal Fluid with Glasgow Outcome Scale for Patients with Tuberculous Meningitis Complicated by Acute Hydrocephalus Treated with Fluid Diversions  Voir?

Tuberculous meningitis (TBM) is an endemic infectious disease in developing countries, and it can become a serious illness in children. Treatment of TBM is more difficult and prone to failure than treatment of pulmonary tuberculosis. TBM causes hydrocephalus, cerebral edema, increased intracranial pressure, global ischemia, and neurologic deficits, which disturb cellular metabolism and increase lactate levels. A reliable, widely available clinical indicator of TBM severity is needed. Successful treatment of TBM is assessed using the Glasgow Outcome Scale (GOS).

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Spinal Epidural Cavernous Hemangioma: A Clinical Series of 7 Patients  Voir?

To investigate imaging characteristics of spinal epidural cavernous hemangiomas (ECHs) and improve understanding of this rare disease.
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Preoperative Embolization of Meningiomas: Differences in Surgical Operability and Histopathologic Changes Between Embosphere and N-butyl 2-cyanoacrylate  Voir?

This study aimed to examine whether there is a difference in the difficulty of extirpation after use of Embosphere versus n-butyl 2-cyanoacrylate (NBCA) for the embolization of meningiomas.
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Serious Concomitant Injuries in Pediatric Patients with Severe Traumatic Brain Injury  Voir?

Severe traumatic brain injury (TBI) is a leading cause of death among children. Although several studies have reported the negative effects of concomitant injuries on mortality in adults with TBI, their effect on pediatric patients remains unclear. Our objective was to describe the effect of serious concomitant injuries on outcomes in pediatric patients with severe TBI.

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Percutaneous Full-Endoscopic Anterior Transcorporeal Procedure for Cervical Disc Herniation: A Novel Procedure and Early Follow-Up Study  Voir?

To describe the surgical technique of percutaneous full-endoscopic anterior transcorporeal cervical discectomy (PEATCD) in detail and report the clinical outcomes and radiologic changes in patients with cervical intervertebral disc herniation (CIVDH).
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Design and application of a novel patient-specific 3D printed drill navigational guiding template in atlantoaxial pedicle screw placement  Voir?

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Rationale Behind the Use of Double-Layer Polypropylene Patch (G-patch) Dural Substitute During Decompressive Craniectomy as an Adhesion Preventive Material for Subsequent Cranioplasty with Special Reference to Flap Elevation Time  Voir?

Dural substitutes are used in decompressive craniectomy (DC) to prevent adhesions during subsequent cranioplasty. Current literature attributes them to reduced blood loss and reduction in operative time of cranioplasty. The use of double-layer substitute has rarely been documented. We studied the use of double-layer G-patch as a dural substitute in DC and evaluated its outcome during subsequent cranioplasty with special focus on flap elevation time and blood loss during cranioplasty.

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Delayed Occurrence of Diabetes Insipidus After Transsphenoidal Surgery with Radiologic Evaluation of the Pituitary Stalk on Magnetic Resonance Imaging  Voir?

Diabetes insipidus (DI) is a major complication of transsphenoidal surgery (TSS). DI usually occurs within a couple of days after TSS. Delayed occurrence of postoperative DI is rarely observed and its developing mechanisms remain unknown.
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Diagnostic Performance of Increased Signal Intensity Within the Resection Cavity on Fluid-Attenuated Inversion Recovery Sequences for Detection of Progression in Patients with Glioma  Voir?

To systematically evaluate the diagnostic performance of increased signal intensity within the resection cavity on fluid-attenuated inversion recovery (FLAIR) sequences for detection of progression in patients with glioma through performing a meta-analysis.
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Cavernous Sinus Hemangioma: Rare Vascular Tumor of Cavernous Sinus  Voir?

Cavernous sinus hemangiomas (CSHs) are rare vascular tumors, which are infrequently encountered in everyday neurosurgical practice. Attempted resection of this lesion without preoperative planning carries a high risk for significant blood loss and cranial neuropathies. Radiation treatments can provide an alternative and safe treatment modality for these lesions. Therefore an increased awareness is warranted for their clinical suspicion. We reported on a patient who presented with visual deficits and a mass in the sellar, suprasellar, and middle fossa regions.

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Comparison of Outcomes in 3 Surgical Approaches for Dystrophic Cervical Kyphosis in Patients with Neurofibromatosis 1  Voir?

To compare outcomes of anterior-only (AO), posterior-only (PO), and anteroposterior (AP) surgical approaches for treatment of dystrophic cervical kyphosis in patients with neurofibromatosis 1 (NF1).
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Hemangioblastomas of the Posterior Cranial Fossa in Adults: Demographics, Clinical, Morphologic, Pathologic, Surgical Features, and Outcomes. A Systematic Review  Voir?

Posterior cranial fossa (PCF) hemangioblastomas are benign, highly vascularized, and well-differentiated tumors with well-described histopathologic features. Although relatively rare, this tumor is the most prevalent primary tumor of the cerebellum in adults.
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Heat Generation During Bony Decompression of Lumbar Spinal Stenosis Using a High-Speed Diamond Drill with or without Automated Irrigation and an Ultrasonic Bone-Cutting Knife: A Single-Blinded Prospective Randomized Controlled Study  Voir?

The main objective of the present prospective, randomized, single-blinded controlled study was to measure heat during bony decompression of lumbar spinal stenosis with high-speed drills and an ultrasonic bone-cutting knife.
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The Outcome of Severe Traumatic Brain Injury in Latin America  Voir?

Traumatic brain injury (TBI) disproportionately affects lower- and middle-income countries (LMIC). The factors influencing outcomes in LMIC have not been examined as rigorously as in higher-income countries.
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Parahippocampectomy as a New Surgical Approach to Mesial Temporal Lobe Epilepsy Caused By Hippocampal Sclerosis: A Pilot Randomized Comparative Clinical Trial  Voir?

The parahippocampal gyrus plays an important role in the epileptogenic pathways of mesial temporal lobe epilepsy caused by hippocampal sclerosis (mTLE-HS); its resection could prevent epileptic seizures with fewer complications. This study evaluates the initial efficacy and safety of anterior temporal lobectomy (ATL), selective amygdalohipppocampectomy (SAH), and parahippocampectomy (PHC) surgical approaches in mTLE-HS.

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Predictors of Readmissions and Reoperations Related to Venous Thromboembolic Events After Spine Surgery: A Single-Institution Experience with 6869 Patients  Voir?

Readmission and reoperation are used as hospital and surgeon quality metrics. Venous thromboembolic (VTE) events, including deep vein thrombosis and pulmonary embolism (PE), are a major cause of readmission, morbidity, and mortality after spine surgery. Specific procedural, perioperative, and patient characteristics may be associated with these outcomes.

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Evaluation of Measuring Methods of Spinal Canal Occupation Rate in Thoracic Ossification of Ligamentum Flavum  Voir?

The degree of hypertrophy of thoracic ossification of ligamentum flavum (TOLF) is related to the severity of the myelopathy. There is no uniform measuring method to calculate the spinal canal occupation ratio (COR) of TOLF simply and effectively. The study was to determine an appropriate measuring method to calculate the COR of TOLF.

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Severe Facial Fracture is Related to Severe Traumatic Brain Injury  Voir?

Facial fractures frequently occur with traumatic brain injury (TBI). The relationship between facial fractures and brain trauma remains controversial. The objective of this study was to analyze the correlation between facial fracture and TBI.
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Adult Spinal Ependymomas: An Epidemiologic Study  Voir?

In adults, spinal ependymomas constitute only 3% to 6% of central nervous system tumors. Because of their rarity and poor prognosis, large population-based studies are needed to assess the epidemiology and survival risk factors associated with these tumors in the hope of improving outcome. The authors undertook this retrospective study to explore factors that may influence survival in adult patients with spinal ependymomas.

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Gamma Knife Stereotactic Radiosurgery for Nonvestibular Cranial Nerve Schwannomas  Voir?

Nonvestibular cranial schwannomas represent a rare type of benign intracranial tumor. Few studies have evaluated the use of stereotactic radiosurgery (SRS) as a primary management option for these lesions. We performed a retrospective review of our institution's experience focusing on efficacy with regard to tumor control and clinical symptom stabilization as well as treatment safety.

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Combined Spinal Arteriovenous Malformation and Spinal Dysraphism  Voir?

Spinal vascular malformations as a group are rare, and coexistence of a spinal arteriovenous malformation (AVM) in or around the spinal dysraphism is extremely rare. We report 2 cases of combined spinal dysraphism and vascular malformations of the spinal cord.
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Rare Thymoma Metastases to the Spine: Case Reports and Review of the Literature  Voir?

We report a series of 3 cases of metastatic thymoma to the spine with spinal cord compression. An extensive literature review of thymic metastases to the spine was completed to provide a comprehensive appraisal of current prognostic indicators and potential treatment algorithms to help guide clinicians in treatment management.

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Spontaneous Spinal Arthrodesis in Stand-Alone Percutaneous Pedicle Screw Fixation Without in Situ Fusion in Patients With Lumbar Segmental Instability: Long-Term Clinical, Radiologic, and Functional Outcomes  Voir?

No study to date has established how commonly spontaneous fusion occurs after stand-alone percutaneous pedicle screw fixation in adult population. In this retrospective single-center study, we investigated the effectiveness, long-term solidity and safety of stand-alone percutaneous pedicle screw fixation without in situ fusion and the influence of presence or absence of fusion on the clinical outcome of patients with low-grade lumbar segmental instability.

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Effect of Smoking Status on Successful Arthrodesis, Clinical Outcome, and Complications After Anterior Lumbar Interbody Fusion (ALIF)  Voir?

Anterior lumbar interbody fusion (ALIF) is a surgical technique indicated for the treatment of several lumbar pathologies. Smoking has been suggested as a possible cause of reduced fusion rates after ALIF, although the literature regarding the impact of smoking status on lumbar spine surgery is not well established. This study aims to assess the impact of perioperative smoking status on the rates of perioperative complications, fusion, and adverse clinical outcomes in patients undergoing ALIF surgery.

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Lumbar Microdiscectomy in Obese Patients: A Multicenter Observational Study  Voir?

To evaluate the association between obesity and outcomes after microdiscectomy for lumbar disc herniation.
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Efficacy of Reinforced Restriction of Physical Activity on Chronic Subdural Hematoma: Prospective Pilot Study  Voir?

Chronic subdural hematoma (CSDH) is a common entity in neurosurgical practice. However, as a result of the high rate in recurrence, morbidity, and mortality for surgical management, conservative management of CSDH is emerging as a new treatment strategy. Head trauma is a known risk factor of CSDH and plays as an initiator in the genesis of CSDH. We hypothesized that physical activity might also play an important role in the progression of an asymptomatic CSDH.

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Risk Factors Analysis for Foot Drop Associated with Lumbar Disc Herniation: An Analysis of 236 Patients  Voir?

To identify the risk factors for foot drop in patients with lumbar disc herniation (LDH).
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Surgical Treatment of Thoracic Spinal Tuberculosis: A Multicenter Retrospective Study  Voir?

The aim of the present multicenter, retrospective study was to assess the safety and effectiveness of different surgery strategies for the treatment of thoracic tuberculosis and to provide a reference for surgical treatment of thoracic tuberculosis.
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Endoscopic Transseptal Approach with Posterior Nasal Spine Removal: A Wide Surgical Corridor to the Craniovertebral Junction and Odontoid: Technical Note and Case Series  Voir?

The transnasal approach to lesions involving the craniovertebral junction represents a technical challenge because of limited inferior exposure. The endoscopic transseptal approach (EtsA) with posterior nasal spine (PNS) removal is described. This technique can create a wide exposure of the craniovertebral junction, thereby increasing the caudal exposure.

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Spontaneous Acute Arterial Subdural Hematoma  Voir?

Spontaneous acute arterial subdural hematoma (SDH) is a rare entity caused by hemorrhage from a cortical perisylvian artery without a known precipitant.
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Magnetic Resonance Imaging Undetectable Epiduroscopic Hotspot in Chronic Diskogenic Back Pain—Does Sinuvertebral Neuropathy Actually Exist?  Voir?

The causes of chronic diskogenic back pain have not yet been clearly identified. Neural ingrowth around the annulus is widely considered to be one of the possible cause. However, neuropathy around the annulus has yet to be observed visually. We report a case of a hotspot that was observed in an epiduroscopic view, but not in imaging findings.

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Long-Term Remission of Recurrent Brainstem Pilocytic Astrocytoma with Neuraxis Dissemination Using Recombinant Human Endostatin After Failure of Vincristine and Carboplatin  Voir?

There is no standard salvage treatment for recurrent and/or unresectable brainstem low-grade gliomas after failure from carboplatin and vincristine chemotherapy. Recombinant human endostatin (rh-ES), a mild inhibitor of angiogenesis, has been used for treating lung cancer. But so far as we know, there is no experience for brainstem gliomas.

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Lateral Ventricular Volume Asymmetry Predicts Poor Outcome After Spontaneous Intracerebral Hemorrhage  Voir?

Midline shift (MLS) has been a known predictor for prognosis after spontaneous intracerebral hemorrhage (ICH), whereas it is secondary to lateral ventricular compression. In this study, we investigated whether lateral ventricular volume (LVV) asymmetry caused by ventricular compression was independently associated with poor outcome of ICH.

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Cervical Rib Prevalence and its Association with Thoracic Outlet Syndrome: A Meta-Analysis of 141 Studies with Surgical Considerations  Voir?

Cervical ribs (CR) are supernumerary ribs that arise from the seventh cervical vertebra. In the presence of CR, the boundaries of the interscalene triangle can be further constricted and result in neurovascular compression and thoracic outlet syndrome (TOS). The aim of our study was to provide a comprehensive evidence-based assessment of CR prevalence and their association with TOS as well as surgical approach to excision of CR and surgical patients' characteristics.

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Microvascular Decompression for Treatment of Trigeminal Neuralgia: Factors That Predict Complete Pain Relief and Study of Efficacy and Safety in Older Patients  Voir?

Microvascular decompression (MVD) is an effective method for directly treating the etiology of trigeminal neuralgia (TGN). This study aims to investigate the factors that predict complete pain relief after MVD for treatment of TGN, and to study efficacy and safety in older patients.
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Determining the Lower Limit of Cerebral Perfusion Pressure in Patients Undergoing Decompressive Craniectomy Following Traumatic Brain Injury  Voir?

In patients with severe traumatic brain injury (TBI), maintaining systolic blood pressure >90 mm Hg, intracranial pressure (ICP) <20 mm Hg and cerebral perfusion pressure (CPP) >60–70 mm Hg is recommended to improve clinical outcomes. A recommended CPP value for patients treated with decompressive craniectomy (DC) has not been clearly studied. We aimed to determine whether the targeted CPP can be lowered in patients treated with DC.

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Rosiglitazone Infusion Therapy Following Minimally Invasive Surgery for Intracranial Hemorrhage Evacuation Decreased Perihematomal Glutamate Content and Blood-Brain Barrier Permeability in Rabbits  Voir?

To observe effects of rosiglitazone (RSG) infusion therapy on perihematomal peroxisome-proliferator-activated receptor gamma (PPARγ), glutamate, blood-brain barrier (BBB) permeability, and brain edema.
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Long-Term Outcome of Repeat Microvascular Decompression for Hemifacial Spasm  Voir?

Although repeat microvascular decompression (MVD) for hemifacial spasm (HFS) in patients with failed prior MVD is potentially curative, little is known about the long-term results of repeat MVD. We aimed to evaluate the long-term outcomes and complications after repeat MVD for HFS.
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Development of a Severe Traumatic Brain Injury Consensus-Based Treatment Protocol Conference in Latin America  Voir?

Severe traumatic brain injury (sTBI) is a significant global health problem disproportionately affecting low- and middle-income countries (LMICs). Management of intracranial hypertension in sTBI is crucial to survival and optimal recovery. Practitioners in high-income countries routinely use intracranial pressure (ICP) monitors although their usefulness has been questioned. ICP monitors are usually unavailable in LMICs. No consensus-based/tested protocols or literature exists for sTBI treatment without ICP monitoring.

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Salvage Therapy for Brain Arteriovenous Malformations After Failure of Gamma Knife Stereotactic Radiosurgery  Voir?

The aim of this study was to investigate delayed complications in patients with brain arteriovenous malformation (BAVM) after Gamma Knife stereotactic radiosurgery and to present the salvage therapy experiences of patients with BAVM with radiation-induced changes (RICs) or intracranial hemorrhage (ICH).

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Virtual Reality–Based Simulators for Cranial Tumor Surgery: A Systematic Review  Voir?

Virtual reality (VR) simulators have become useful tools in various fields of medicine. Prominent uses of VR technologies include assessment of physician skills and presurgical planning. VR has shown effectiveness in multiple surgical specialties, yet its use in neurosurgery remains limited.
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Evaluation of Patency After Vascular Anastomosis Using Quantitative Evaluation of Visualization Time in Indocyanine Green Video Angiography  Voir?

In vascular reconstructive surgery, intraoperative confirmation of patency is performed by angiography, Doppler, or indocyanine videoangiography, but it is sometimes insufficient.
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Self-Inflicted Drywall Screws in the Sagittal Sinus  Voir?

A 30-year-old right-handed man with a history of schizophrenia presented with 2 self-inflicted drywall screws in the skull. The patient was sleepy but easily arousable; blood tests showed he had taken methamphetamines. Computed tomography and computed tomography angiography of the head showed the frontal screw abutted left of the superior sagittal sinus, and the posterior screw went through the superior sagittal sinus with no extravasation of contrast material at either site. Both screws were removed with exposure of the sagittal sinus using U-shaped craniectomies.

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Utility of Retrograde Amnesia Assessment Alone, Compared with Anterograde Amnesia Assessment in Determining Recovery After Traumatic Brain Injury: Prospective Cohort Study  Voir?

Posttraumatic amnesia (PTA) after traumatic brain injury (TBI) comprises anterograde amnesia (AA), disorientation, and retrograde amnesia (RA). However, RA is often neither assessed nor emphasized. A recent study demonstrated that although AA and disorientation were both present in non-TBI inpatients uniformly taking opioids, RA was absent. This suggests potentially significant utility with RA assessment alone since opioids are commonly prescribed post TBI.

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Collet-Sicard Syndrome Attributable to Extramedullary Plasmacytoma of the Jugular Foramen  Voir?

Collet-Sicard syndrome is a rare manifestation of skull base disease involving the jugular and hypoglossal foramina. We report the first case of Collet-Sicard attributable to extramedullary plasmacytoma—multiple myeloma (EP-MM) and the second case of EP-MM precipitating a jugular foramen syndrome (JFS)-spectrum disorder.

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Microsurgical Clipping of a Giant Middle Cerebral Artery Aneurysm with Successful Postoperative Endovascular Mechanical Thrombectomy for Emergent Treatment of Large Vessel Occlusion  Voir?

Giant intracranial aneurysms (>25 mm) are uncommon. These lesions typically manifest clinically due to mass effect, acute hemorrhage, or thromboembolic events. To minimize the risk of poor clinical outcome, detailed operative planning and a consideration of all neurosurgical and endovascular techniques are essential before proceeding with microsurgical clipping of ruptured giant aneurysms.

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Acute Bilateral Isolated Foot Drop: Changing the Paradigm in Management of Degenerative Spine Surgery with Percutaneous Endoscopy  Voir?

Acute bilateral isolated foot drop due to lumbar disk prolapse with canal stenosis is rare with only 3 cases reported in literature. Our patient was managed using the percutaneous full endoscopic technique. This is mainly to highlight the ease of access and patient outcome with preoperative and postoperative images to support our minimally invasive treatment for this rare condition.

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Subtemporal “Interdural” Surgical Approach for “Giant” Facial Nerve Neurinomas  Voir?

The management issues of 15 cases of giant and dumbbell-shaped facial neurinomas that extended both in the middle and posterior cranial fossa are reported.
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Risk Factors and Microbiology of Meningitis and/or Bacteremia After Transsphenoidal Surgery for Pituitary Adenoma  Voir?

To investigate the incidence, bacteriologic features, and risk factors of posttranssphenoidal surgery (post-TSS) meningitis and/or bacteremia.
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Postoperative Neurologic Outcome in Patients with Pituitary Apoplexy After Transsphenoidal Surgery  Voir?

Pituitary apoplexy can cause severe neuro-ophthalmologic or endocrinologic sequelae, requiring timely treatment. The present study was performed to evaluate postoperative neurologic outcomes and to identify their risk factors in patients who underwent transsphenoidal surgery for pituitary apoplexy.
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Clinical Application of an Open-Source 3D Volume Rendering Software to Neurosurgical Approaches  Voir?

Preoperative recognition of the anatomic individualities of each patient can help to achieve more precise and less invasive approaches. It also may help to anticipate potential complications and intraoperative difficulties. Here we describe the use, accuracy, and precision of a free tool for planning microsurgical approaches using 3-dimensional (3D) reconstructions from magnetic resonance imaging (MRI).

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Health-Related Quality of Life and Posttraumatic Growth in Low-Grade Gliomas in China: A Prospective Study  Voir?

The present study aimed to describe the quality of life (QoL) changes of survivors of low-grade gliomas (LGGs) 1 year after surgery and to identify determinants of QoL with an emphasis on the role of perceived posttraumatic growth (PTG). We also tried to examine the linear and quadratic relationship between QoL and PTG.

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Pial Arteriovenous Fistula: A Brief Review and Report of 14 Surgically Treated Cases  Voir?

The authors report their successful experience of treating 14 cases of pial arteriovenous fistula (PAVF) by direct surgery.
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Prognostic Role of Microembolic Signals After Endovascular Treatment in Anterior Circulation Ischemic Stroke Patients  Voir?

Endovascular treatment (EVT) is an effective therapy for acute ischemic stroke due to large artery occlusion of the anterior circulation. Yet some patients do not experience clinical improvement despite successful recanalization and reperfusion. The reasons are unknown, but one possible explanation is microvessel obstruction downstream. The aim of this study was to assess the presence of microembolic signals (MES) with transcranial Doppler and define their role as predictors of clinical outcome in stroke patients after EVT.

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Evaluation of Enterprise Stent-Assisted Coiling and Telescoping Stent Technique as Treatment of Supraclinoid Blister Aneurysms of the Internal Carotid Artery  Voir?

Supraclinoid blister aneurysms (BAs) of the internal carotid artery are uncommon and deadly, and appropriate treatment is controversial. Endovascular reconstruction may allow treatment through aneurysm isolation. We report a single-institution experience in the use of Enterprise stent-assisted coiling (ESAC) for treating BAs to appraise the safety and efficacy of this technique.

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What Should We Do for Those Hemifacial Spasm Patients Without Efficacy Following Microvascular Decompression: Expectation of Delayed Relief or Early Reoperation?  Voir?

Although microvascular decompression (MVD) has been widely accepted as an effective treatment for hemifacial spasm (HFS), some patients may experience delayed relief instead of immediate improvement after the surgery. The need for and timing of repeat MVD has been controversial to date; thus, we conducted the present study with emphasis on those unrelieved patients.

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Oncogenic viruses in Skull Base Chordomas.  Voir?

Chordomas are rare tumors assumed to derive from notochordal remnants. We believe that a molecular switch is responsible for their malignant behaviour. However, the involvement of oncogenic viruses has not been studied. Thus, in the present study we investigate the presence of oncogenic viruses in chordomas.

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Early and Late Posttraumatic Epilepsy in the Setting of Traumatic Brain Injury: A Meta-analysis and Review of Antiepileptic Management  Voir?

Moderate to severe traumatic brain injury confers increased risk of posttraumatic seizures (PTSs). Early PTSs are diagnosed when seizures develop within 7 days after injury, whereas seizures diagnosed as late PTSs occur later. Patients have been treated with phenytoin (PHT) to prevent early PTSs and more recently with levetiracetam (LEV). Various regimens have been tried in patients to prevent late PTSs with variable success. We assessed and compared effectiveness of these drugs on early and late PTS prevention.

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Web Vessels: Literature Review and Neurointerventional Management  Voir?

The aim of this study was to describe 27 patients with 32 web vessels (WVs) from our practice and provide a review of the literature regarding imaging diagnostics, clinical presentation, and treatment of WVs.
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Treatment of Brain Arteriovenous Malformations with Hemodynamic Aneurysms: A Series of 131 Consecutive Cases  Voir?

The natural history of hemodynamic aneurysms (HAs) associated with brain arteriovenous malformations (AVMs) remains controversial, with no single approach to treatment. The purpose of this study was to justify preventive treatment tactics for HAs that pose an increased risk of rupture based on hemodynamic studies demonstrating hypertension in the afferent bed after AVM exclusion.

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Effectiveness of Ipsilateral Stroke Prevention Between Conservative Management and Indirect Revascularization for Moyamoya Disease in a North American Cohort  Voir?

Few reports have compared surgical intervention with conservative treatment for moyamoya disease (MMD) in non-Asian cohorts. This study describes the effectiveness of follow-up stroke prevention by indirect revascularization relative to conservative management in a Northeast United States study population.

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The Influence of Sedation Level Guided by Bispectral Index on Therapeutic Effects for Patients with Severe Traumatic Brain Injury  Voir?

Sedation therapy is vital for treating severe traumatic brain injury (TBI). Yet, types of sedation assessment tools and sedation levels that are suitable for sedation treatment have not been investigated.
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Deep Brain Stimulation for Essential Tremor: A Comparison of Targets  Voir?

Deep brain stimulation (DBS) is an established treatment for refractory essential tremor (ET). Initially, the target of choice was the thalamic ventralis intermedius nucleus (VIM). However, the zona incerta (ZI) has been suggested as a superior target. Both targets are considered safe and effective, but a direct comparison between these targets is lacking.

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Coagulation Factor Hyperfunction After Subarachnoid Hemorrhage Induces Deep Venous Thrombosis  Voir?

To explore the change of coagulation function and associated potential mechanisms and the relationship between coagulation disorders and deep venous thrombosis (DVT) after subarachnoid hemorrhage (SAH) within 3 days of onset.
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Atypical and Malignant Meningiomas: Neurooncologic Management in a Brazilian cohort  Voir?

To analyze the surgical and oncologic treatment of a Brazilian cohort of patients with grade II and III meningioma at a follow-up time of 15 years to get an overview of these patients' outcomes.
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The Incidence and Risk Factors of In-Stent Restenosis for Vertebrobasilar Artery Stenting  Voir?

In-stent restenosis (ISR) remains a challenge for vertebrobasilar artery stenting (VBAS). We aimed to investigate the incidence and risk factors of ISR.
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The Enigma of Orbital Compartment Syndrome After Lumbar Spine Surgery in the Prone Position: Case Report and Literature Review  Voir?

Perioperative visual loss after spinal surgery is a devastating complication for the patient and the surgical team. Two known major causes are ischemic optic neuropathy and central retinal artery occlusion (CRAO). Traditional understanding of CRAO has been consistently related to occurrence of periocular trauma and signs of increased intraorbital pressure in addition to visual loss. However, such orbital signs are not a feature of any common perioperative visual loss syndrome.

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Patched Closure of Dural Outlet of External Ventricular Drainage Catheter: Better Way to Prevent Cerebrospinal Fluid Leakage  Voir?

Postoperative continuous bloody cerebral spinal fluid drainage with external ventricular drainage catheter could decrease the incidence of inflammation. But the drainage catheter left in place will interrupt the watertight dura matter closure. To prevent the related cerebrospinal fluid leakage and subgaleal pseudomeningocele after the catheter removal, we developed a patched closure method to seal the dural outlet of the drainage catheter with a favorable clinical outcome.

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One-Level or Multilevel Interbody Fusion for Multilevel Lumbar Degenerative Diseases: A Prospective Randomized Control Study with a 4-Year Follow-Up  Voir?

The treatment of multilevel lumbar degenerative disease (LDD) is complicated and challenging, and the optimal surgical strategy remains controversial.
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Association of SOX17 Gene Polymorphisms and Intracranial Aneurysm: A Case-Control Study and Meta-Analysis  Voir?

Genome-wide association studies have revealed an association between SRY-box 17 (SOX17) gene and intracranial aneurysm (IA) formation. However, results were mainly derived from European and Japanese populations. We investigated the association between SOX17 gene polymorphisms and IA in a homogeneous Korean population. We performed a meta-analysis to assess these results in East-Asian populations.

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Optic Nerve Meningioma Mimicking Cavernous Hemangioma  Voir?

A 38-year-old woman presented with rapidly worsening, painless right monocular vision loss. An examination revealed a visual acuity of 1.4/10 and a central scotoma in the right eye. The orbital magnetic resonance imaging (MRI) showed a well-delineated ovoid intraconal mass of the right eye, hyperintense on T2-weighted MRI with homogenous enhancement after contrast injection. The mass abutted and displaced the optic nerve. A diagnosis of cavernous hemangioma was evoked, which is the most common benign adult orbital mass with these MRI features.

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Intracranial Erdheim-Chester Disease Mimicking Parafalcine Meningioma: Report of Two Cases and Review of the Literature  Voir?

Erdheim-Chester disease (ECD) is a rare, non-Langerhans cell histiocytosis that typically occurs in middle-aged patients. It is usually characterized by multifocal osteosclerotic lesions of the long-bones, however many cases have extraskeletal involvement. Central nervous system (CNS) involvement is common, but isolated CNS involvement at presentation has rarely been reported.

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Intraventricular Glioblastoma Multiforme in A Child with L2-Hydroxyglutaric Aciduria  Voir?

L2-hydroxyglutaric aciduria (L2-HGA) is a rare neurometabolic disease characterized by accumulation of L2-hydroxyglutarate (L2-HG), a potential oncometabolite resulting in significant lifetime risk for cerebral tumors. Herein, we present a case of intraventricular glioblastoma multiforme (GBM) in a 16-year-old child with L2-HGA who presented with rapid functional decline and persistent vomiting. The tumor was completely resected, and the patient remained well at 2-year follow-up. Clinicians should be aware of the usual insidious nature of the disease.

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Surgery for Recurrent High-Grade Glioma After Treatment with Bevacizumab  Voir?

Bevacizumab (BVZ) is an antiangiogenic agent approved by the Food and Drug Administration that is used for the treatment of recurrent glioblastoma. Complications related to impaired healing may adversely affect patients resected for recurrent high-grade glioma (HGG) after treatment with BVZ.
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History, Current Situation, and Future Development of Endoscopic Neurosurgery in China  Voir?

During the past few decades, Chinese endoscopic neurosurgery has rapidly developed in synchrony with the rest of the world. The aim of this article is to review the development of Chinese endoscopic neurosurgery, including its birth, growth, current situation, and prospects.
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Adult Pilocytic Astrocytoma: An Institutional Series and Systematic Literature Review for Extent of Resection and Recurrence  Voir?

Pilocytic astrocytoma is a classically benign tumor that most often affects pediatric patients. Rarely, it occurs during adulthood. We present a case series and systematic literature review of adult pilocytic astrocytoma (APA) to examine the clinical presentation, extent of resection, and recurrence rate associated with this tumor in this population.

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Cerebellar Mutism Syndrome and Other Complications After Surgery in the Posterior Fossa in Adults: A Prospective Study  Voir?

Cerebellar mutism syndrome (CMS) is rarely described in adults; however, data on self-assessed linguistic complications after posterior fossa surgery do not exist.
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Prevalence of Surgically Untreated Face, Head, and Neck Conditions in Uganda: A Cross-Sectional Nationwide Household Survey  Voir?

The Surgeons OverSeas Assessment of Surgical Need tool (SOSAS) was created to evaluate the burden of surgically treatable conditions in low- and middle-income countries. The goal of our study is to describe the face, head, and neck (FHN) conditions that need surgical care in Uganda, along with barriers to that care and disability from these conditions.

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Quantitative Volumetric Analysis Following Magnetic Resonance–Guided Laser Interstitial Thermal Ablation of Cerebellar Metastases  Voir?

Treating recurrent posterior fossa metastases after previous radiation therapy and surgical resection remains challenging. Magnetic resonance laser-induced thermal therapy (MR-LITT) is a promising treatment for recurrent lesions, but data on safety, efficacy, and postablation volume change in the posterior fossa are lacking.

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The pCONus2 Neck-Bridging Device: Early Clinical Experience and Immediate Angiographic Results  Voir?

Treating wide-necked aneurysms is challenging for the interventional neuroradiologist. Recently, numerous devices dedicated to the treatment of these aneurysms have become available. We report our early experience using the pCONus2 device and present the technical success rate, clinical outcomes, and immediate angiographic occlusion rates.

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Transvenous Embolization of Ethmoidal Dural Arteriovenous Fistulas: Case Series and Review of the Literature  Voir?

Ethmoidal dural arteriovenous fistulas (DAVFs) are rare and aggressive lesions, usually treated by microsurgical disconnection of the fistula. Transarterial embolization rarely is performed because of the risk of retinal ischemia. Transvenous embolization has been reported as an alternative approach. We describe our experience in transvenous embolization of ethmoidal DAVFs and review the literature focusing on technical and safety aspects of the procedure.

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Neurologic Deterioration in Patients with Moyamoya Disease during Pregnancy, Delivery, and Puerperium  Voir?

We reviewed our clinical experience of patients with moyamoya disease (MMD) who gave birth and assessed characteristics of those experiencing neurologic deterioration.
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Rupture Resemblance Models May Correlate to Growth Rates of Intracranial Aneurysms: Preliminary Results  Voir?

Treatment of intracranial aneurysms (IAs) is largely guided by IA size and growth. Preliminary investigations have found a relationship between clinical factors and growth; yet, the relationship between morphologic and hemodynamic risk prediction models in IA growth is unknown.
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Long-Term Outcome After Carotid Endarterectomy in Patients with Ischemic Heart Disease  Voir?

The long-term outcome after carotid endarterectomy (CEA) is determined by many confounding factors. Ischemic heart disease (IHD) is linked to atherosclerotic stroke, and it is an important cause of death during the perioperative and follow-up periods after CEA. We aimed to investigate mortality and long-term major adverse cardiovascular events (MACEs) in patients with IHD compared with patients who do not have IHD.

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A simple new screw insertion technique without extraction for broken pedicle screws  Voir?

Spinal transpedicular screw fixation is widely performed. Broken pedicle screw rates range from 3 to 7.1%. Several techniques have been described for extraction of broken pedicle screws. However, most of these techniques require special instruments. We describe a simple, modified technique for management of broken pedicle screws without extraction. No special instruments or drilling in an adjacent pedicle are required.

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Changes in Blood Flow Velocity of the Middle Cerebral Artery After Carotid Endarterectomy: Daily Assessment with Transcranial Color-Coded Sonography  Voir?

Hyperperfusion syndrome (HPS) is a well-known complication of carotid endarterectomy (CEA) warranting repeatable inexpensive monitoring. Transcranial color-coded sonography (TCCS) may provide a potential modality for such monitoring, but little is known about TCCS trends after CEA.
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Expression of CD133 as a Putative Prognostic Biomarker to Predict Intracranial Dissemination of Primary Spinal Cord Astrocytoma  Voir?

Spinal cord astrocytoma with intracranial dissemination carries a poor prognosis. The mechanisms leading to dissemination remain to be elucidated. A stem cell marker, CD133, was reported to predict recurrence patterns in intracranial glioblastoma. We evaluated the significance of CD133 as a putative prognostic biomarker to predict intracranial dissemination in spinal cord astrocytoma.

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Surgical Orthopedics in a Spondylometaphyseal Dysplastic Patient  Voir?

Spondylometaphyseal dysplasia (SMD) is a rare disease characterized by vertebral and metaphyseal abnormalities. The treatment of SMD spinal deformities remains a challenge for spinal surgeons. The purpose of this study is to demonstrate the feasibility and effectiveness of vertebral column resection of SMD by thoracolumbar kyphosis and scoliosis.

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The Patient Size Setting: A Novel Dose Reduction Strategy in Cerebral Endovascular Neurosurgery Using Biplane Fluoroscopy  Voir?

In some fluoroscopy machines, the dose-rate output of the fluoroscope is tied to a selectable patient size. Although patient size may play a significant role in visceral or cardiac procedures, head morphology is less variable, and high dose outputs may not be necessary even in very obese patients. We hypothesized that very small patient size setting can be used to reduce dose for cerebral angiography without compromising image quality.

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Effectiveness of Gamma Knife Radiosurgery in Improving Psychophysical Performance and Patient's Quality of Life in Idiopathic Trigeminal Neuralgia  Voir?

To assess effectiveness of Gamma Knife Radiosurgery (GKRS) in improving quality of life (QoL) in patients with idiopathic trigeminal neuralgia (TN).
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In Situ Side-to-Side Anastomosis: Surgical Technique and Complication Avoidance  Voir?

In situ side-to-side (STS) anastomosis is a unique technique used for intracranial artery–intracranial artery revascularization. Over a 7-year period, 7 STS anastomoses were performed for anterior cerebral artery aneurysms in 6 patients and a posteroinferior cerebellar artery aneurysm in 1 patient. We provide a step-by-step guide for suturing techniques from arteriotomy to vessel wall sutures based on clinical experiences, with detailed illustrations. Technical considerations in each stage are also discussed.

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A Novel Skin and Fascia Opening for Subfascial Inserting of Intrathecal Baclofen Pump  Voir?

The aim of this article is to introduce a new skin and fascia opening for intrathecal baclofen pump implantation in the abdomen, with the purpose of reducing complications related to wound breakdown.
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Angiographic Appearance of Pulsatile Blister Aneurysm  Voir?

A male with detected subarachnoid hemorrhage was admitted to our center. During the first angiography, a pulsatile blister aneurysm was revealed and the aneurysm was also noticeably enlarged during the surveillance angiography. The patient accepted balloon-assisted clipping successfully. Blister aneurysms are at a high risk of rupture, high risk of regrowth, and need for multimodal management.

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Efficiency and Safety of Autologous Fat Grafts in Reconstructing Skull Base Defects After Resection of Skull Base Meningiomas  Voir?

Reconstruction of the skull base after resection of skull base meningiomas is of paramount importance. Here we describe a safe and effective method of skull base reconstruction using autologous free fat grafts.
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Repair of Cerebrospinal Fluid Leakage Using a Transfrontal, Radial Adipofascial Flap: An Individual Approach Supported by Three-Dimensional Printing for Surgical Planning  Voir?

Leakage of cerebrospinal fluid (CSF) because of large prolactinomas represents a complex issue. Because of limited anatomic space, multiple leakage sites, and scarce locally available tissue for repair, surgical possibilities are limited. We report an initial case of using a radial fasciocutaneous flap applied subfrontally to cover a large skull base defect, supported by preoperative three-dimensional (3D) printing for surgical planning.

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Rare Concurrent Retroclival and Pan-Spinal Subdural Empyema: Review of Literature with an Uncommon Illustrative Case  Voir?

Subdural empyema can present as a spinal subdural empyema (SSE) or a cranial subdural empyema (CSE). Although they differ somewhat in epidemiology, etiology, pathophysiology, and symptomatology and occur separately, they rarely manifest together. The aim of this article is to review the literature concerning the clinical presentation, clinical course, and treatment options for managing concurrently occurring SSE and CSE.

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Hybrid Recanalization for Symptomatic Long-Segmental Occlusion Post Vertebral Artery Stenting  Voir?

A hybrid operation combining endovascular and open surgery procedures is supposed to achieve recanalization for post-stenting long-segmental occlusion of the vertebral artery (VA) ostium simultaneously.
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Paradoxical Distraction with Upright Position After Halo Fixation in 2 Patients with Atlanto-Occipital Dislocation  Voir?

Atlanto-occipital dislocation (AOD) is the most uncommon form of traumatic cervical spine injury. The majority of patients die before reaching higher-level care, and only a small percentage of patients with AOD survive the initial injury after receiving tertiary care. As such, there is a paucity of evidence-based management guidelines for treating this condition. Halo vest fixation has been a proposed method for interim stability while these patients undergo medical optimization for surgical intervention.

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Predicting Resident Performance from Preresidency Factors: A Systematic Review and Applicability to Neurosurgical Training  Voir?

Neurosurgical educators strive to identify the best applicants, yet formal study of resident selection has proved difficult. We conducted a systematic review to answer the following question: What objective and subjective preresidency factors predict resident success?
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Endovascular Mechanical Thrombectomy in Large-Vessel Occlusion Ischemic Stroke Presenting with Low National Institutes of Health Stroke Scale: Systematic Review and Meta-Analysis  Voir?

Mechanical thrombectomy has become the standard of care for management of most large vessel occlusion (LVO) strokes. When patients with LVO present with minor stroke symptomatology, no consensus on the role of mechanical thrombectomy exists.
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Midline Ligamentum Flavum Cyst of Lumbar Spine  Voir?

Ligamentum flavum cysts are thought to develop due to facet joint hypermobility; however, the etiology of these lesions is not completely elucidated. These cysts may lead to compressive pathologies of the spine requiring surgical intervention.
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Utility of the Lateral Base Dural Tacking Method in Cord Tumor Surgery Performed Using Unilateral Hemilaminectomy: A Comparison of Dural Window Widths  Voir?

Unilateral hemilaminectomy, which is used to remove spinal cord tumors, is simpler than laminoplastic laminotomy and affords certain biomechanical advantages. However, both incomplete tumor removal and inadvertent infliction of spinal cord damage attributable to the narrow surgical corridor remain of concern. When a spinal cord tumor is to be removed, it is important to ensure that the dural window along the surgical corridor is of adequate width. This study aimed to determine that the utility of lateral base dural tacking (LBT) method when cord tumor surgery is performed using a unilateral hemilaminectomy—a comparison of dural window widths with a traditional dural tack-up and a suspending-out (DSO) method with the aid of digital image-analysis software.

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Association of Hospital Teaching Status with Neurosurgical Outcomes: An Instrumental Variable Analysis  Voir?

The interpretation of the results of prior studies on the association of hospital teaching status with surgical outcomes is limited by selection bias. We investigated whether undergoing surgical operations in teaching hospitals is associated with improved outcomes.
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A Randomized Controlled Trial of Low-Dose Tranexamic Acid versus Placebo to Reduce Red Blood Cell Transfusion During Complex Multilevel Spine Fusion Surgery  Voir?

Multilevel spine fusion surgery for adult deformity correction is associated with significant blood loss and coagulopathy. Tranexamic acid reduces blood loss in high-risk surgery, but the efficacy of a low-dose regimen is unknown.
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Hypoglossal Schwannoma of Neck: Case Report and Review of Literature  Voir?

Schwannomas are benign, slow-growing neoplasms of the myelin-producing Schwann cells of peripheral nervous system that most commonly affect sensory nerves. Hypoglossal schwannomas, tumors of purely motor nerves, comprise <5% of all head and neck schwannomas. Since the first description of a hypoglossal schwannoma in 1933, there have been few case reports of extracranial origins. The most common location of an extracranial hypoglossal schwannoma is in the parapharyngeal space and can mimic paragangliomas.

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Borderline Alberta Stroke Programme Early CT Score Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion May Find Benefit with Endovascular Thrombectomy  Voir?

Selection of patients with acute ischemic stroke for endovascular thrombectomy (EVT) is complex and time-critical. Benefits of EVT are well established for patients with small core infarcts. The aim of this study was to compare clinical outcomes of EVT in patients with larger established infarcts (Alberta Stroke Programme Early CT Score [ASPECTS] ≤6) with patients with smaller infarcts (ASPECTS 7–10).

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Surgical Management and Long-Term Seizure Outcome After Surgery for Temporal Lobe Epilepsy Associated with Cerebral Cavernous Malformations  Voir?

Operative strategies for cerebral cavernous malformation (CCM)-associated temporal lobe epilepsy and timing of surgical intervention continue to be debated. This study aimed to establish an algorithm to evaluate the efficacy of surgical intervention strategies, to maximize positive surgical outcomes and minimize postsurgical neurologic deficits.

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Brain Granuloma: Rare Complication of a Retained Catheter  Voir?

Ventriculoperitoneal (VP) shunt is the most frequent treatment for hydrocephalus. VP shunt malfunction is a very common problem in neurosurgical practice, often requiring shunt revision procedures. In some cases, complete removal of a VP shunt may present difficulties, leading the surgeon to leave the ventricular catheter in situ. This decision is often made to avoid possible adverse events, primarily risk of life-threatening hemorrhage. However, a nonfunctioning catheter left in the ventricular system may lead to further complications.

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Flat-Detector Computed Tomography for Evaluation of Intracerebral Vasculature for Planning of Stereoelectroencephalography Electrode Implantation  Voir?

Stereoelectroencephalography (sEEG) requires extensive preoperative planning to optimize placement of electrodes and limit the potential for complications. Flat-detector computed tomography (FD-CT) has previously been used for perioperative vascular imaging to guide the treatment of vascular lesions. This imaging modality provides a detailed depiction of cerebrovascular and bony cranial anatomy, which can be used to guide intracranial electrode implantation. We have developed a novel method to improve preoperative planning for sEEG electrode implantation and limit the potential for postoperative complications by using FD-CT imaging merged with preoperative magnetic resonance imaging (MRI).

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Gamma Knife Surgery for Recurrent Trigeminal Neuralgia in Cases with Previous Microvascular Decompression  Voir?

Microvascular decompression (MVD) and Gamma Knife surgery (GKS) are the primary treatments for trigeminal neuralgia (TN). However, many patients require further surgical treatment after initial surgery for recurrent TN. The aim of this study was to evaluate efficacy and safety of GKS for recurrent TN cases with prior MVD.

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Cost-Effectiveness of Postoperative Ketamine in Chiari Decompression  Voir?

In Chiari I patients, postoperative pain and discomfort frequently slow the transition back to the home setting.
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Reliability of Tokuhashi Score to Predict Prognosis: Comparison of 117 Patients  Voir?

Spinal metastatic disease compromises the quality of life and prognosis of the patients. Prognosis is an important factor for the decision-making process and needs to be precise in order to adjust the intensity of therapy. The Tokuhashi score is a universal instrument to determine the prognosis. The objective was to analyze the effectiveness of the Tokuhashi score in determining the prognosis of the patients with spine metastasis by comparing the expected survival time from the Tokuhashi score with the survival time observed among surgical patients.

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Surgical Outcome of Very Small Intracranial Aneurysms Utilizing the Double Clip Technique  Voir?

To report the outcome of patients with very small intracranial aneurysm (VSIA) undergoing surgical clipping using a double-clip technique.
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Surgical Resection of Anterior and Posterior Butterfly Glioblastoma  Voir?

Evidence suggests a survival benefit for patients with glioblastoma who undergo maximal safe surgical resection. Not all glioblastomas are amenable to surgical resection and anatomic location is one potentially limiting factor. Glioblastomas that invade the corpus callosum and cross midline to the contralateral hemisphere—butterfly glioblastomas (bGBMs)—are one subgroup of tumors traditionally deemed inoperable.

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The Impact of Aneurysm Location on Incidence and Etiology of Hyponatremia Following Subarachnoid Hemorrhage  Voir?

Hyponatremia is the most common electrolyte abnormality in patients with aneurysmal subarachnoid hemorrhage (aSAH). Syndrome of inappropriate antidiuretic hormone secretion (SIADH) and cerebral salt wasting (CSW) are the most common etiologies. Whether or not the location of the ruptured aneurysm is associated with the etiology of hyponatremia is unknown. We sought to determine whether or not the incidence of SIADH and CSW after aSAH differed based on aneurysm location.

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Risk Factors Associated with Readmission and Reoperation in Patients Undergoing Spine Surgery  Voir?

Reoperation and readmission are often avoidable, costly, and difficult to predict. We sought to identify risk factors for readmission and reoperation after spine surgery and to use these factors to develop a scoring system predictive of readmission and reoperation.
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Adult Patients with Pneumococcal Meningitis at a Neurosurgical Neurologic Center: Different Predisposing Conditions?  Voir?

In previous studies of pneumococcal meningitis in adults within general hospitals or national cohorts, the most common predisposing conditions were otitis media, sinusitis, pneumonia, immunosuppression, alcoholism, and diabetes. The epidemiology of pneumococcal meningitis is changing because of the use of vaccines in childhood, and antibiotic resistance has increased.

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Usefulness of 18F-fluorodeoxyglucose−Positron Emission Tomography in Comparison with Methionine−Positron Emission Tomography in Differentiating Solid Hemangioblastoma from Adult Cerebellar Tumors  Voir?

Among adults with posterior fossa tumors, an intraaxial location of the tumor is less common than an extraaxial location. Moreover, the differential diagnosis of a single cerebellar tumor in adults is sometimes difficult by conventional magnetic resonance imaging. We aimed to report the findings of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) and methionine in adult patients with intraaxial and solitary metastatic brain tumors.

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Risk Factors of Postoperative Sacroiliac Joint Pain for Posterior Lumbar Surgery: ≥2-Year Follow-up Retrospective Study  Voir?

A retrospective study was conducted to clarify the risk factors of postoperative sacroiliac joint pain (SIJP) for posterior open lumbar surgery.
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Medical Malpractice in Neurosurgery: A Comprehensive Analysis  Voir?

Of all specialists, neurosurgeons have the highest probability of facing a medical malpractice claim. Here we report the first specialty-wide review of malpractice claims in neurosurgery performed using a well-established national online legal database.
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Observation of Effects of Different Surgical Treatments on Unilateral Masticatory Muscle Spasm  Voir?

Unilateral masticatory muscle spasm is a rare disease without a generally accepted and efficacious treatment plan.
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Sagittal Alignment as Predictor of Adjacent Segment Disease After Lumbar Transforaminal Interbody Fusion  Voir?

This study was carried out to explore the diagnostic value of sagittal measurements for adjacent segment disease after lumbar transforaminal interbody fusion (TLIF).
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Microsurgical Treatment of Ruptured Intracranial Aneurysms in Sub-Saharan Africa: A Series of 102 Consecutive Cases Treated in Senegal  Voir?

In sub-Saharan Africa, the management of ruptured intracranial aneurysms (RIAs) is difficult for many reasons. In this retrospective, 3-year study, the authors will demonstrate the particularities of the management of RIAs in Senegal.
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Novel Minimally Invasive Treatment Strategy for Acute Traumatic Epidural Hematoma: Endovascular Embolization Combined with Drainage Surgery and Use of Urokinase  Voir?

Hematoma evacuation is regular treatment for acute traumatic epidural hematoma (ATEDH) patients meeting with surgery indications. However, it is an invasive approach performed under general anesthesia. Here, a novel minimally invasive method of endovascular embolization with subsequent drainage surgery and use of urokinase was established to treat ATEDH under local anesthesia.

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Cost-Effectiveness of Endoscopic Versus Microscopic Transsphenoidal Surgery for Pituitary Adenoma  Voir?

Endoscopic transsphenoidal surgery (ETPS) has become increasingly popular for resection of pituitary tumors, whereas microscopic transsphenoidal surgery (MTPS) also remains a commonly used approach. The economic sustainability of new techniques and technologies is rarely evaluated in the neurosurgical skull base literature. The aim of this study was to determine the cost-effectiveness of ETPS compared with MTPS.

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A Novel Dissection Method Using a Flexible Neuroendoscope for Resection of Tumors Around the Aqueduct of Sylvius  Voir?

Flexible endoscopes have both a wide range of movement and a wide field of view and are therefore widely used for endoscopic third ventriculostomy and biopsy. However, tumor resection around the aqueduct of Sylvius using flexible endoscopes has scarcely been reported.
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Postoperative Gamma Knife Radiosurgery for Cavernous Sinus–Invading Growth Hormone–Secreting Pituitary Adenomas  Voir?

We aimed to determine the long-term effects of Gamma knife radiosurgery (GKS) on remnants in the cavernous sinus (CS) after transsphenoidal surgery (TSS) for acromegaly and to identify its possible adverse effects.
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The Relationship Between Hematoma and Pachymeninges in an Interdural Hematoma: Diagnosis and Surgical Strategy  Voir?

The exact location of a hematoma in relation to the pachymeninges contributes to typical radiographic presentations. However, because of the complexity of hematoma evolution and neomembrane formation, an unexpected intraoperative finding can lead to a change of surgical strategy. In addition, the concentration of hemoglobin and its degradation products, the integrity of red blood cells, and the infiltration of fibroblasts, polymorphonuclear neutrophils, and macrophages are factors that affect the imaging characteristics on computed tomography and magnetic resonance imaging as the hematoma ages.

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Intraoperative Monitoring of the Integrity of the Anterior Visual Pathways: A Methodologic Review and Meta-Analysis  Voir?

Diverse methods have been developed for intraoperative monitoring of the integrity of the visual pathways. We performed a review of the literature to determine the methodology of each technique as well as their recent development. The predictive power of each eligible technique was determined based on a meta-analysis.

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Small Cell Glioblastoma of the Sella Turcica Region: Case Report and Review of the Literature  Voir?

Glioblastomas in the sellar region are very rare; in most cases, the tumor originates from the optic nerve or optic chiasm. Only 4 cases of sellar glioblastoma with a nonoptic origin have been reported. We present such a case with detailed clinical, imaging, and histopathologic information. We also review similar published cases.

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Pediatric Nonmissile Penetrating Head Injury: Case Series and Literature Review  Voir?

Pediatric nonmissile penetrating head injury (NMPHI) is usually accidental attributed mainly to the softer skulls of growing children. However, it is a rare entity, and therefore no consensus exists regarding treatment to effectively prevent immediate and long-term complications. Throughout the literature, these injuries are mostly discussed in case reviews and case series in the general population. No data originating from randomized studies are available because of ethical and practical limitations.

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Risks of Endoscopic Temporal Ventriculocisternostomy for Isolated Lateral Ventricle: Anatomic Surgical Nuances  Voir?

Entrapment of the temporal horn, known as isolated lateral ventricle (ILV), is a rare type of noncommunicating focal hydrocephalus, and standard treatment has not been established. We report 2 cases of endoscopic surgery for ILV and highlight the anatomic surgical nuances to avoid associated surgical risks.

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Delayed Traumatic Aortic Pseudoaneurysm Formation Causing Vertebral Body Erosion and Back Pain: Case Report and Literature Review  Voir?

Aortic pseudoaneurysms are a rare cause of chronic back pain, usually resulting from compression of the adjacent neurovasculature. It is uncommon for patients with pseudoaneurysms of the abdominal aorta to present in a delayed fashion after initial traumatic injury.
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Posterior Lumbar Interbody Fusion with 3D-Navigation Guided Cortical Bone Trajectory Screws for L4/5 Degenerative Spondylolisthesis: 1-Year Clinical and Radiographic Outcomes  Voir?

We describe our technique and evaluate clinical and radiographic outcomes for patients undergoing L4/5 posterior lumbar interbody fusion with 3D-navigation guided cortical bone trajectory screws (PLIF-CBT) for grade 1 or 2 degenerative spondylolisthesis with a minimum follow-up time of 12 months.
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Transtentorial Distortion Syndrome: Consistent Complication Following Lateral and Fourth Ventricular Shunting in Adults  Voir?

Complex hydrocephalus affecting lateral and fourth ventricles separately is occasionally managed with cerebrospinal fluid diversion via supratentorial and infratentorial ventricular catheters. The optimal configuration to reduce complications is currently unknown in adults. We describe a consistently similar clinical presentation of patients with complex hydrocephalus and a fourth ventricle separately drained by infratentorial shunt insertion.

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Surgical Treatment of Spinal Synovial Cysts in Elderly Patients: Symptoms, Treatment Course, and Outcome in Patients >75 Years of Age  Voir?

With the aging of our society comes a rising number of elderly patients with progressive degeneration of the spine associated with synovial cysts. Surgical treatment may be particularly challenging in elderly patients because of comorbidities.
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The Effect of Steroids on Complications, Readmission, and Reoperation After Posterior Lumbar Fusion  Voir?

The effects of chronic corticosteroid therapy on complications, readmission, and reoperation after posterior lumbar fusion (PLF) remain underinvestigated, and were examined to determine differences in outcomes.
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Intradural–Extramedullary Cervical Cord Lipoma: Case Report and Literature Review  Voir?

Spinal lipomas are generally thought to occur as a result of failed primary neurulation. Failed primary neurulation allows invasion of mesenchymal tissue of mesodermic origin into the neural structure, leading to the formation of a spinal lipoma. Despite most spinal lipomas being regarded as the result of failed primary neurulation, some confusion in terms of the embryogenesis of spinal lipomas remains. Recently, a novel classification of spinal lipomas based on embryonic changes seen during primary and secondary neurulation was has been proposed.

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Enterprise Deployment Through PulseRider To Treat Anterior Communicating Artery Aneurysm Recurrence  Voir?

PulseRider (Pulsar Vascular, Los Gatos, California, USA) is a new endovascular device designed to treat wide-neck bifurcation intracranial aneurysms. Deployment of a stent through a PulseRider to treat an aneurysm's recurrence has never been described before.
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Fusion, Failure, Fatality: Long-term Outcomes After Surgical Versus Nonoperative Management of Type II Odontoid Fracture in Octogenarians  Voir?

Type II odontoid fracture is a highly morbid injury among octogenarians, with 41% 1-year mortality. Our objective was to assess long-term fusion, complication, and survival rates.
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Unruptured Versus Ruptured AVMs: Outcome Analysis from a Multicentric Consecutive Series of 545 Surgically Treated Cases  Voir?

Recent literature strongly challenged indications to perform preventive surgery in unruptured arteriovenous malformation (AVM) claiming that invasive AVM treatment is associated with a significant risk of complications and thus conservative management may be a preferable alternative in many patients. On the other hand, the recent improvement of surgical instrumentation and treatment strategies (both surgical and interventional) yielded better outcomes than those achieved only a decade ago. Therefore, even among specialists, a wide variety of opinions, concerning the treatment of unruptured AVM, can be found.

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Cerebral Hyperperfusion Syndrome After Endovascular Reperfusion Therapy in a Patient with Acute Internal Carotid Artery and Middle Cerebral Artery Occlusions  Voir?

Cerebral hyperperfusion syndrome (CHS) is known to be a rare but devastating complication of carotid artery revascularization. Because patients with acute ischemic stroke due to acute major cerebral and/or cervical artery occlusion treated with endovascular reperfusion therapy may have impaired autoregulation in the cerebral vasculature, these patients may also develop CHS. Despite the growing number of endovascular reperfusion procedures for acute ischemic stroke, this complication has only rarely been reported.

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Efficacy of Biomedical Glue Sling Technique Versus Traditional Technique for Microvascular Decompression for Hemifacial Spasm with Refractory Hypertension  Voir?

Microvascular decompression (MVD) is useful treatment for hemifacial spasm (HFS) with refractory hypertension (RHTN). The biomedical glue sling technique is a new method for MVD. In this study, we retrospectively compared the outcome of the biomedical glue sling technique with traditional technique in MVD for HFS with RHTN.

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Epidemiology and Management of Spinal Trauma in Children and Adolescents <18 Years Old  Voir?

This retrospective study reports the epidemiology, clinical aspects, and management of spinal trauma in children and adolescents.
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Rupture of Intraventricular Hydatid Cyst: Camalote Sign  Voir?

Only a few cases of intraventricular hydatid cysts have been described. The camalote or water lily sign is described when there is detachment of the endocyst membrane, resulting in a floating appearance like a water lily. This sign has been described most commonly in hepatic cysts. Here, we describe the camalote sign in an iatrogenically ruptured intraventricular hydatid cyst. Rupture of an intraventricular hydatid cyst poses the threat of widespread dissemination and is described in our case.

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A Novel Technique for Cervical Facet Joint Hyperplasia-Spondylotic Radiculopathy by Laminar and Lateral Mass Screw Cofixations  Voir?

We sought to describe the novel technique and report the outcomes of cervical spondylotic radiculopathy caused by facet joint hyperplasia treated with minimally invasive surgery by laminar and lateral mass screw cofixations.
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Predictors of Hospital Length of Stay and 30-Day Readmission in Cervical Spondylotic Myelopathy Patients: An Analysis of 3057 Patients Using the ACS-NSQIP Database  Voir?

Hospital length of stay (LOS), 30-day readmission rate, and other metrics are increasingly being used to evaluate quality of surgical care. The factors most relevant to cervical spondylotic myelopathy (CSM) are not yet established.
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Posterior Cervical Laminectomy Results in Better Radiographic Decompression of Spinal Cord Compared with Anterior Cervical Discectomy and Fusion  Voir?

Cervical spondylitic myelopathy is a degenerative condition resulting from chronic spinal cord compression and a leading cause of nontraumatic spinal cord dysfunction. The chief surgical goal in the management of cervical spondylitic myelopathy is adequate spinal cord decompression with or without fusion to slow or prevent further neurologic decline. We conducted a radiographic analysis of canal parameters preoperatively and postoperatively for patients undergoing either anterior or posterior cervical decompression.

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Is There an Indication for Intraoperative MRI in Subtotal Resection of Glioblastoma? A Multicenter Retrospective Comparative Analysis  Voir?

Surgery in patients with highly eloquent glioblastoma (GB) remains challenging. The aim of this study was to evaluate influence of use of intraoperative magnetic resonance imaging (iMRI) on extent of resection (EOR), clinical outcome, and survival in patients with preoperatively intended subtotal resection of GB.

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Outcome of Transforaminal Epidural Steroid Injection According to Severity of Cervical Foraminal Stenosis  Voir?

Cervical transforaminal epidural steroid injection (TFESI) is considered one of the most effective treatments for radicular pain induced by cervical foraminal stenosis.
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The Optimal Treatment Options of Septated Chronic Subdural Hematoma: A Retrospective Comparison of Craniotomy Versus Endoscopic-Assisted Burr-Hole Craniostomy  Voir?

To complete a retrospective comparison of endoscope-assisted burr-hole craniostomy (EBHC) and craniotomy in the treatment of septated chronic subdural hematoma (SCSH).
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Preoperative Assessment of Craniopharyngioma Adherence: Magnetic Resonance Imaging Findings Correlated with the Severity of Tumor Attachment to the Hypothalamus  Voir?

Craniopharyngioma (CP) adherence represents a heterogeneous pathologic feature that critically influences the potentially safe and radical resection. The aim of this study was to define the magnetic resonance imaging (MRI) predictors of CP adherence severity.
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Traumatic Fractures of the Cervical Spine: Analysis of Changes in Incidence, Cause, Concurrent Injuries, and Complications Among 488,262 Patients from 2005 to 2013  Voir?

The causes and epidemiology of traumatic cervical spine fracture have not been described with sufficient power or recency. Our goal is to describe demographics, incidence, cause, spinal cord injuries (SCIs), concurrent injuries, treatments, and complications of traumatic cervical spine fractures.
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The Effect of Obesity on Clinical Outcomes After Minimally Invasive Surgery of the Spine: A Systematic Review and Meta-Analysis  Voir?

Obesity is associated with increasing morbidity and mortality in many prevalent diseases, especially lumbar degenerative disease. The relationship between minimally invasive surgery (MIS) of the spine and perioperative adverse events in obese patients with lumbar degenerative disease has not been well evaluated.

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Comparison of Results Between Posterior Fossa Decompression with and without Duraplasty for the Surgical Treatment of Chiari Malformation Type I: A Systematic Review and Meta-Analysis  Voir?

Posterior fossa decompression without (PFD) or with duraplasty (PFDD) for the treatment of type 1 Chiari malformation (CM-1) is controversial. We thus performed a systematic review and meta-analysis of studies to assess the effect on clinical and imaging improvement, operative time, complications, and recurrence rate between PFD and PFDD in patients with CM-1.

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Anterior Transdiscal Axial Screw Fixation for Subaxial Cervical Spine: A Biomechanical Study  Voir?

To evaluate stability of anterior transdiscal axial screw (ATAS) fixation for anterior instrumentation and to compare with standard anterior cervical decompression and fusion and plate (ACDFP) fixation in human subaxial cervical spine.
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Comparison of Clinical and Radiographic Outcomes for Posterior Fossa Decompression with and without Duraplasty for Treatment of Pediatric Chiari I Malformation: A Prospective Study  Voir?

The aim of this study was to prospectively compare the radiographic and clinical outcomes between the posterior fossa decompression (PFD) and PFD with duraplasty (PFDD) procedures in adolescent patients with Chiari malformation type I (CMI).
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Atlanto-Occipital Rotatory Dislocation: A Case Report and Systematic Review  Voir?

Atlanto-occipital rotatory dislocation (AORD) has rarely been reported in the literature; for this reason, the clinicoradiologic characteristics of this injury are not well described.
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Neuroendoscopic Treatment of Cystic Craniopharyngiomas: A Case Series with Systematic Review of the Literature  Voir?

Total removal of craniopharyngiomas is burdened by high morbidity. In cases of a cystic or mixed craniopharyngioma, when the symptoms are caused by the cystic component of the tumor, a less invasive surgical approach aiming at cyst drainage may be recommended. Here, we report our experience with intraventricular neuroendoscopy, describe our clear-cut surgical technique, and analyze results in the context of literature data.

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Clinical Characteristics of Lumbosacral Spinal Dural Arteriovenous Fistula (DAVF)–Comparison with Thoracic DAVF  Voir?

Spinal dural arteriovenous fistula (DAVF) occurs at any spinal level, but the clinical characteristics of lumbosacral DAVF have not been well documented. The purpose of this study was to evaluate clinical characteristics of lumbosacral DAVF and compare these features with those in thoracic DAVF.
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Correlation Between Contrast Time–Density Time on Digital Subtraction Angiography and Flow: An in Vitro Study  Voir?

Digital subtraction angiography (DSA) provides an excellent anatomic characterization of cerebral vasculature, but hemodynamic assessment is often qualitative and subjective. Various clinical algorithms have been produced to semiquantify flow from the data obtained from DSA, but few have tested them against reliable flow values.

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Effectiveness of a Decision-Making Protocol for the Surgical Treatment of Lumbar Stenosis with Grade 1 Degenerative Spondylolisthesis  Voir?

Addition of fusion to decompression for stenosis with grade 1 degenerative spondylolisthesis is a controversial topic, and the question remains if fusion provides any benefit to the patient that warrants the increased health care utilization and perioperative morbidity. There is no consensus on indications for use of fusion over decompression alone.

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Effects of Low Bone Mineral Status on Biomechanical Characteristics in Idiopathic Scoliotic Spinal Deformity  Voir?

Low bone mass in patients with adolescent idiopathic scoliosis has been well reported. Poor bone quality was regarded as a new and unique prognostic factor in aggravating curve progression. However, the potential biomechanical correlation between them remains unclear.
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Retrosigmoid Intradural Suprameatal-Inframeatal Approach for Complete Surgical Removal of a Giant Recurrent Vestibular Schwannoma with Severe Petrous Bone Involvement: Technical Case Report  Voir?

Surgical removal of giant vestibular schwannomas with severe petrous bone involvement remains challenging due to the high risk of complications. The retrosigmoid intradural suprameatal-inframeatal approach (RISIA) allows for safe exposure extending from Meckel's cave to the petrous internal carotid artery (ICA).

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Treatment of Spontaneous Dissecting Aneurysm in Extracranial Vertebral Artery with Covered Stent  Voir?

To treat a 13-year-old boy with a spontaneous vertebrobasilar artery dissecting aneurysm in the extracranial artery, which was only 1 mm away from the initial segment of subclavian artery.
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Risk Factors for the Rupture of Intracranial Aneurysms Using Computed Tomography Angiography  Voir?

To study the clinical and morphologic characteristics associated with risk factors for the rupture of intracranial aneurysms (IAs).
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Are Antiplatelet and Anticoagulants Drugs A Risk Factor for Bleeding in Mild Traumatic Brain Injury?  Voir?

Facing mild traumatic brain injury, clinicians must decide whether to perform a computed tomography (CT) scan to detect a potential intracranial hemorrhage. Many useful guidelines have been developed for the general population, but there is no general consensus about the best practice to adopt when dealing with patients on antiplatelet or anticoagulation drugs. The relatively recent introduction of new anticoagulants and second-generation antiplatelet drugs poses new challenges in this field. There are no data in the literature about the relative risk of intracranial bleeding in such categories.

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Low-Grade Glioma with Foci of Early Transformation Does Not Necessarily Require Adjuvant Therapy After Radical Surgical Resection  Voir?

Low-grade glioma (LGG) is a slow-growing tumor often found in young adults with minimal or no symptoms. As opposed to true low-grade lesions such as dysembryoplastic neuroepithelial tumors, they are associated with continuous growth and inevitable malignant transformation.
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What's New in Spinal Coccidioidomycosis?  Voir?

This commentary is written in reference to the article by Martinez-del-Campo et al1 titled “Spinal Coccidioidomycosis: Current Review of Diagnosis and Management.” The purpose of this study was to review the risk factors and clinical presentations, discuss the indications for surgical intervention, and evaluate outcomes and complications after medical and surgical management. A review of the English-language literature yielded 40 articles, of which there were 7 case series and 11 case reports, with a total of 140 patients being reported.

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Nerve Transfers in Patients with Brown-Séquard Pattern of Spinal Cord Injury: Report of 2 Cases  Voir?

Use of distal nerve transfer for improving upper limb function has been well described for patients with tetraplegic spinal cord injury and brachial plexus injuries but has not previously been described for Brown-Séquard type spinal cord injury. We describe our experience with 2 cases of combined Brown-Séquard injury and unilateral brachial amyotrophy.

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Mammillothalamic and Mammillotegmental Tracts as New Targets for Dementia and Epilepsy Treatment  Voir?

Recently, neuromodulation through deep brain stimulation (DBS) has appeared as a new surgical procedure in the treatment of some types of dementia and epilepsy. The mammillothalamic and mammillotegmental tracts are involved among the new targets. To our knowledge, a review article focused specifically on these mammillary body efferents is lacking in the medical literature. Their contribution to memory is, regrettably, often overlooked.

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Decompressive Craniectomy for Spontaneous Intracerebral Hemorrhage: A Systematic Review and Meta-analysis  Voir?

Spontaneous intracerebral hemorrhage (sICH) is a devastating disease with high mortality and morbidity, and the application of decompressive craniectomy (DC) in sICH is controversial. We conducted a systematic review to verify the effects of DC on improving outcome in sICH.
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C2 Body as “Keystone” in Management of C1-C2-C3 Dislocation Secondary to Congenital Absence of C2 Posterior Elements  Voir?

Congenital absence of C2 posterior arch may present with C2-C3 dislocation. Previously these cases were managed by fusing occiput-C1-C4 without including C2 in the construct. Such constructs are likely to immobilize the long segment of the cervical spine, and exclusion of C2 may not yield the best result.

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Readmissions in Patients with Anticoagulated Intracranial Hemorrhage: A Retrospective Review  Voir?

To determine the effect of direct oral anticoagulants (DOACs) compared with warfarin on the 30-day readmission rates in patients with traumatic intracranial hemorrhage (ICH).
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Cerebral Venous Sinus Thrombosis Following Second Transsphenoidal Surgery: Report of a Rare Complication and Review of Literature  Voir?

Cushing disease, induced by a pituitary adrenocorticotropic hormone (ACTH)-secreting adenoma, is associated with high risk of stroke. At present, transsphenoidal surgery remains the first line of therapy. Cerebral venous sinus thrombosis (CVST) is an uncommon form of stroke with variable presentations. There are no previous reports of its occurrence in patients with Cushing disease following transsphenoidal surgery.

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Overcoming End-to-End Vessel Mismatch During Superficial Temporal Artery–Radial Artery–M2 Interposition Grafting for Cerebral Ischemia: Tapering Technique  Voir?

Cerebral revascularization procedures, such as the external carotid–internal carotid bypass, have been used in the clinical management of cerebral ischemic states. Among the most commonly performed bypasses is the superficial temporal artery–middle cerebral artery (STA-MCA) bypass to restore cerebral blood flow. In cases of a foreshortened STA donor vessel, a radial artery (RA) graft is often used as an interposition graft between the STA and MCA. However, addressing the vessel size mismatch between the radial artery and donor can be problematic and challenging.

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Postsurgical Cavity Evolution After Brain Metastasis Resection: How Soon Should Postoperative Radiosurgery Follow?  Voir?

Postoperative stereotactic radiosurgery (SRS) to the cavity after resection of brain metastases improves local control. We hypothesized that significant cavity constriction would occur from the immediate postoperative period to the time of SRS and aimed to elucidate optimal treatment timing.
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Efficacy of Using Intermediate Screws in Short-Segment Fixation for Thoracolumbar Fractures: A Meta-Analysis of Randomized Controlled Trials  Voir?

Some studies have reported that the conventional intersegmental pedicle screws (4-screw fixation [4S]) device for thoracolumbar fractures was associated with inadequate reduction of fractured vertebrae, insufficient correction of kyphosis, and implant failure. Recently, a series of biomechanical studies has confirmed that the addition of intermediate fixation screws (6-screw fixation [6S]) could provide stronger fixation and better reduction of fractured vertebrae. Nevertheless, the clinical and radiologic efficacy of the additional intermediate screws remains unclear.

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Long-Term Follow-Up of Patients with Metastatic Epidural Spinal Cord Compression from Breast Cancer Treated with Surgery Followed by Radiotherapy  Voir?

To evaluate role of surgery plus radiotherapy (RT) in patients with metastatic epidural spinal cord compression from breast cancer with a follow-up >10 years.
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Dwell Time of Stentriever Influences Complete Revascularization and First-Pass TICI 3 Revascularization in Acute Large Vessel Occlusive Stroke  Voir?

In acute ischemic stroke with large vessel occlusion, the interaction between the clot retriever and the stent is critical for achieving successful recanalization. The ideal time of stent deployment (dwell time [DT]) to improve revascularization is currently unknown. We systematically analyzed the effect of different DT on final angiographic and clinical outcomes of patients who underwent mechanical thrombectomy.

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Neurosurgery in Octogenarians: A Prospective Study of Perioperative Morbidity, Mortality, and Complications in Elderly Patients  Voir?

The aging population in industrialized countries shifts the age limit for neurosurgical interventions toward increasingly older patients. This study investigates whether octogenarians (≥80 years) stand out in outcome and incidence of perioperative complications.
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Evaluation of the Use of Calcium Phosphate Cement for Aesthetic Neurosurgical Cranial Reconstruction  Voir?

The objective of this article is to evaluate whether newly developed calcium phosphate cement (CPC), mounted around the titanium plates, is useful for aesthetic cranial reconstruction by using 2 methods.
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Patients with a Normal Pressure Hydrocephalus Shunt Have Fewer Complications than Do Patients with Other Shunts  Voir?

Ventriculoperitoneal (VP) shunting is a well-established therapy for hydrocephalus. However, complications are frequent. The incidence of idiopathic normal pressure hydrocephalus (NPH) increases with the aging of the population. We evaluated the functional status of patients and the classification of complications associated with VP shunt procedures in our center.

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Surgical Outcomes After Segmental Limited Surgery for Adjacent Segment Disease: The Consequences of Makeshift Surgery  Voir?

To minimize surgical morbidity, surgeons may opt to perform segmental limited surgery instead of fusion extension for adjacent segment disease (ASD) after lumbar fusion surgery. This study evaluated clinical outcomes from segmental limited surgery without fusion extension for ASD and assessed which clinical factors were associated with reoperation after segmental limited surgery.

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Unplanned intraoperative extubations in pediatric neurosurgery: analysis of case series to increase patient safety  Voir?

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Dural Penetration of Cavernous Hemangioma on Skull: Uncommon Clinical Presentation  Voir?

Cavernous hemangioma (CH) of the bone is a rare, benign neoplasm found usually in the vertebral body. This tumor rarely develops in the calvaria, with predilection to occur in the frontal and temporoparietal bones.
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The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion  Voir?

To determine whether preoperative chronic kidney disease (CKD) is associated with inferior perioperative outcomes in patients undergoing lumbar arthrodesis.
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Endoscopic Approach to Clival Chordomas: The Northwestern Experience  Voir?

Chordomas are rare primary bone tumors with a low-grade histology but an aggressive clinical behavior characterized by local invasion and recurrence. When occurring in the skull base, their treatment is limited by proximity to critical neurovascular structures. Open surgical approaches can carry high morbidity, making the development of alternative approaches desirable. We describe our experience with endoscopic endonasal approaches to clival chordomas over 13 years.

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Clinical features of precocious, synchronous, and metachronous brain metastases and the role of tumor resection  Voir?

The purpose of this study was to clarify clinical features, outcomes, and the role of tumor resection in precocious, synchronous, and metachronous brain metastases. Methods Brain metastases were found before primary cancer detection in the precocious group, within 2 months after primary cancer detection in the synchronous group, and 2 months or later after primary cancer detection in the metachronous group.

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Suboccipital Decompressive Craniectomy for Cerebellar Infarction: A Systematic Review and Meta-Analysis  Voir?

Suboccipital decompressive craniectomy (SDC) for cerebellar infarction has been traditionally performed with minimal high-quality evidence. The aim of this systematic review and meta-analysis is to investigate the impact of SDC on functional outcomes, mortality, and adverse events in patients with cerebellar infarcts.

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High Cervical Spinal Cord Compression Associated with Anomaly of Bilateral Vertebral Arteries  Voir?

Anomalies of the vertebral arteries are rare and usually detected incidentally. However, very rarely, they can manifest with clinical symptoms. We describe such a symptomatic case of high cervical spinal cord compression associated with persistent C2 segmental arteries.
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Impact of Operating Room Environment on Postoperative Central Nervous System Infection in a Resource-Limited Neurosurgical Center in South Asia  Voir?

Postoperative central nervous system infections (PCNSIs) are serious complications following neurosurgical intervention. We previously investigated the incidence and causative pathogens of PCNSIs at a resource-limited, neurosurgical center in south Asia. This follow-up study was conducted to analyze differences in PCNSIs at the same institution following only one apparent change: the operating room air filtration system.

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Differentiating Between Primary Central Nervous System Lymphomas and Glioblastomas: Combined Use of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging  Voir?

The purpose of this study was to determine whether combined diffusion-weighted imaging and dynamic susceptibility contrast-enhanced perfusion-weighted imaging magnetic resonance imaging can be used to differentiate between common malignant brain tumors, including lymphomas and high-grade gliomas.
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Anatomic Study of Extracranial Needle Trajectory Using Hartel Technique for Percutaneous Treatment of Trigeminal Neuralgia  Voir?

The aim of this study was to describe the anatomic trajectory of the extracranial needle for percutaneous rhizotomy and correlate this with structures at risk during such a procedure.
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An Evaluation of Commonly Used External Ventricular Drain Securement Methods in a Porcine Model: Recommendations to Improve Practice  Voir?

External ventricular drain (EVD) dislodgement is common and leads to significant morbidity and mortality. Many securement techniques to prevent this are described. There are, however, no objective studies comparing them. This study aimed to determine the most secure method of securing an EVD.
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Surgical Revascularization for Children with Moyamoya Disease: A New Modification to the Pial Synangiosis  Voir?

To summarize therapeutic efficacy of modified pial synangiosis in children with moyamoya disease and our experience with this method.
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“July Effect” on Care for Aneurysmal Subarachnoid Hemorrhage  Voir?

Subarachnoid hemorrhage (SAH) following a ruptured intracranial aneurysm accounts for about 5% of strokes, with an incidence of 10.5 per 100,000 person years (about 27,000 patients per year).1 Outcome after aneurysmal SAH depends on several factors, including the severity of the initial hemorrhage, rebleeding, perioperative medical management, and the timing and technical success for aneurysm exclusion from the cerebral circulation.2 The overall mortality rates range from 32% to 67% with 10%–20% of patients with long-term dependence due to brain damage.

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Presacral Tarlov Cyst as an Unusual Cause of Abdominal Pain: New Case and Literature Review  Voir?

A presacral Tarlov cyst is an unusual cause of abdominal pain. The unusual location of a presacral Tarlov cyst can lead to misdiagnosis and inappropriate treatment. To guide appropriate diagnosis and treatment, we reviewed causes, clinical presentations, radiologic features, and management options of this extremely rare lesion.

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Pituitary Ependymoma: A Case Report and Review of the Literature  Voir?

Pituitary ependymoma is exceptionally rare. Its etiology, clinical presentation, radiologic feature, and treatment strategy are still a matter of debate. Only 7 human cases with limited data were reported in the English literature, and now we described another case of pituitary ependymoma. We also systematically reviewed previously reported cases and described its potential etiology, clinical presentation, radiologic features, pathology, immunohistochemical analysis, and ultrastructural examinations.

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Epidural Steroids at Closure After Microdiscectomy/Laminectomy for Reduction of Postoperative Analgesia: Systematic Review and Meta-Analysis  Voir?

This review assessed the efficacy of epidural steroid administration on the reduction of pain, hospital stay time, and use of opioid analgesics postoperatively.
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Prognostic Factors for the Survival Outcome of Bilateral Thalamic Glioma: An Integrated Survival Analysis  Voir?

The aim of this study was to perform an integrated survival analysis of patients with bilateral thalamic glioma and to assess the influence of various prognostic factors on overall survival.
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Matriderm for Management of Scalp Necrosis Following Surgical Treatment of Giant Parietal Encephalocele  Voir?

Management of encephaloceles is challenging when massive brain herniation is present. In such instances, an expansile cranioplasty may be attempted so as to preserve some herniated brain tissue. Complications such as wound dehiscence, cerebrospinal fluid leak, and scalp necrosis are postoperative concerns. The treatment of scalp necrosis with dural and brain exposure is certainly a challenge due to the complexity of flap techniques in such a young age. Herein we describe the use of a novel technique for the management of a scalp necrosis and dehiscence in an infant.

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Subarachnoid-to-Subarachnoid Shunt for Correction of Nonfunctioning Baclofen Pump in a Severe Case of Chronic Debilitating Post–Spinal Cord Injury Spasticity  Voir?

Perhaps the most disabling condition seen in patients with spinal cord injury (SCI) is spasticity. Spasticity is characterized as hyperreflexia and hypertonicity as a result of damage to the supraspinal tracts in the aftermath of SCI. Intrathecal baclofen (ITB) is the mainstay therapy for spasticity unresponsive to oral baclofen. One of the problems associated with post-SCI spasticity unresponsive to ITB is the development of scar tissue that prevents the diffusion of baclofen in the desired spinal cord area.

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Regression of Giant Calcified Thoracic Disk and Spinal Cord Compression Following Thoracic Laminectomy and Posterior Instrumented Fusion  Voir?

The authors present a case report of a patient with a giant thoracic calcified disc. The patient underwent a posterior thoracic laminectomy and fusion without resection of the disc. The calcified disc regressed in size and lost its calcified component postoperatively.
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Development of Life-Size Patient-Specific 3D-Printed Dural Venous Models for Preoperative Planning  Voir?

Despite significant improvement in clinical care, operative strategies, and technology, neurosurgery is still risky, and optimal preoperative planning and anatomical assessment are necessary to minimize the risks of serious complications. Our purpose was to document the dural venous sinuses (DVS) and their variations identified during routine 3-dimensional (3D) venography created through 3D models for the teaching of complex cerebral anatomy.

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How Early Can We Perform Cranioplasty for Traumatic Brain injury After Decompressive Craniectomy? A Retrospective Multicenter Study  Voir?

Decompressive craniectomy (DC) is used to treat intractable intracranial hypertension after severe traumatic brain injury (TBI). Cranioplasty (CP) is typically performed weeks or months later. However, the optimal timing for CP is unknown. We aimed to determine the earliest possible time point for CP.

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Spontaneously Resolving Symptomatic Subdural Hygromas After Cerebellopontine Angle Tumor Surgery  Voir?

Subdural hygroma is a rare disease most commonly encountered in posttraumatic patients. Even more rarely, it has been described as a complication of cerebellopontine angle tumor requiring surgical evacuation.
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Infection Incidence Associated with External Ventriculostomy Placement: A Comparison of Outcomes in the Emergency Department, Intensive Care Unit, and Operating Room  Voir?

External ventricular drain (EVD) placement is a common neurosurgical procedure used to control acute hydrocephalus and other neurosurgical complications. The infection and complication rates reported in the literature are highly variable, and iatrogenic factors determine the outcome of drain placement. We examined the impact of the setting of EVD placement (emergency department [ED] vs. intensive care unit [ICU] vs. operating room [OR]) and the experience of the operating surgeon on the infection rate, complication rate, EVD replacement, eventual placement of a ventriculoperitoneal shunt, and the need for further surgical intervention.

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Case of Subarachnoid Hemorrhage Caused by Tuberculous Aneurysm  Voir?

Subarachnoid hemorrhage caused by rupture of tuberculosis associated aneurysm is a rare complication. In this paper, we report a case of intracranial tuberculum with adjacent intracerebral inflammatory aneurysm which caused subarachnoid hemorrhage and brain abscess formation.
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Brainstem Cavernous Malformations: Surgical Indications Based on Natural History and Surgical Outcomes  Voir?

Cavernous malformations (CMs) are uncommon lesions occurring in the central nervous system, with an incidence of approximately 0.5% in the general population and constituting 5%–10% of all intracranial vascular malformations. Among CMs, prevalence within the brainstem as reported in the literature has ranged from 4% to 35%. With their precarious location and potentially devastating clinical events, brainstem CMs have attracted attention from neurosurgeons, and with these surgeons' unrelenting efforts, the microsurgical techniques to treat these lesions in the brainstem have greatly improved in recent decades.

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Effect of Progesterone on Cerebral Vasospasm and Neurobehavioral Outcomes in a Rodent Model of Subarachnoid Hemorrhage  Voir?

Subarachnoid hemorrhage (SAH) induces widespread inflammation leading to cellular injury, vasospasm, and ischemia. Evidence suggests that progesterone (PROG) can improve functional recovery in acute brain injury owing to its anti-inflammatory and neuroprotective properties, which could also be beneficial in SAH. We hypothesized that PROG treatment attenuates inflammation-mediated cerebral vasospasm and microglial activation, improves synaptic connectivity, and ameliorates functional recovery after SAH.

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Isolated Transverse Process Spinal Fractures Increase the Likelihood of Incurring Visceral and Pelvic Injuries: A Retrospective Review at a Level-1 Trauma Center  Voir?

Although isolated transverse process fractures (ITPF) do not confer any inherent risk of compromised spinal stability, there is increasing interest in their overall prognostic significance. As a proxy for localized or directional forces in high-energy traumatic mechanisms, ITPF may serve as an indicator for the presence of other coexisting traumatic injuries. Specific injuries may be predicted by the presence of ITPF at specific spinal levels, but few studies have examined this in depth and may not account for confounding variables.

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Tentorial Meningiomas: Reappraisal of Surgical Approaches and Their Outcomes  Voir?

Tentorial meningiomas are notorious for their critical location. Selection of a suitable approach that exposes the multicompartmental growth of tumor is important for a complete and safe resection. This paper discusses about various operative approaches and their overall surgical outcome.
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Systematic Review of Woven EndoBridge for Wide-Necked Bifurcation Aneurysms: Complications, Adequate Occlusion Rate, Morbidity, and Mortality  Voir?

Although the Woven EndoBridge (WEB [Sequent Medical, Aliso Viejo, California, USA]) is a highly innovative technique for the endovascular treatment of wide-necked bifurcation aneurysms (WNBAs), there are no studies available comparing this technique with surgical results or other endovascular results of stent-assisted coiling or balloon-assisted coiling for WNBAs. The purpose of this study was to assess complications, complete occlusion rate, and morbidity and mortality of the WEB in WNBA treatment.

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Prosthetic Replacement of the Ocular Surface Ecosystem Treatment of Ocular Surface Disease After Skull Base Tumor Resection  Voir?

Prosthetic replacement of the ocular surface ecosystem (PROSE) treatment is an effective, nonsurgical therapeutic option for patients with ocular surface disease related to cranial nerve deficits secondary to skull base tumor resection.
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Adolescent Idiopathic Scoliosis Surgery by a Neurosurgeon: Learning Curve for Neurosurgeons  Voir?

To determine a neurosurgeon's learning curve of surgical treatment for adolescent idiopathic scoliosis (AIS) patients.
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Severe Spinal Cord Compression by Pure Giant Intradural Schwannoma of Cervical Spine  Voir?

Giant intradural extramedullary schwannoma of the cervical spine usually causes severe spinal cord compression. This type of tumor has a low incidence. Patients present progressive loss of strength and other functions of the spinal cord. This article shows the clinical images of a 75-year-old male with the diagnosis of giant intradural extramedullary schwannoma and the cases reported in the literature.

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Rapid Progression of Ossification of the Posterior Longitudinal Ligament After Anterior Cervical Discectomy and Fusion  Voir?

Ossification of the posterior longitudinal ligament (OPLL) has a reported incidence of 1.9%–4.3%. Disease progression is associated with surgery, with most studies focusing on OPLL progression after laminoplasty. The continued range of motion following surgery is believed to place strain on adjacent levels, driving calcification of the ligament. We present a case of marked progression of OPLL at levels adjacent to a previous anterior cervical discectomy and fusion.

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Malignant Cerebral Swelling After Cranioplasty: Case Report and Literature Review  Voir?

Cranioplasty is considered a low-risk operation in the field of neurosurgery following decompression craniectomy. Well-known complications after cranioplasty, such as infection, seizure, and titanium plate exposure, may not threaten the lives of patients. Unfortunately, there are many fatal complications that are underreported. In this study, we report a case and perform a literature review to introduce malignant cerebral swelling, which is regarded as a devastating complication.

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Coccidioidomycosis for Neurosurgeons  Voir?

Coccidioidomycosis is a relatively rare, airborne infectious disease, caused by spores of Coccidioides immitis or posadasii. The Coccidioides fungus lives in the top 2–8 inches of soil and is endemic in parts of northern Mexico and Central and South America, as well as the southwestern United States, namely Arizona and California. Also known as “Valley Fever” or “Desert Fever,” the incidence of this disease has been steadily increasing in the past 2 decades. Initially recognized as an individually reportable disease in 1995 in California, the incidence has increased from 8.4 cases per 100,000 population in 2009 to 13.7 cases in 2016.

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The Middle Temporal Artery: Surgical Anatomy and Exposure for Cerebral Revascularization  Voir?

The middle temporal artery (MTA) is the proximal medial branch of the superficial temporal artery (STA), supplying the temporalis muscle along with deep temporal arteries. Its use in vascularized flaps for reconstructive and otologic procedures has been described, yet its potential use in neurosurgery has not been studied. We report a novel technique for exposing the MTA and evaluated its characteristics for extracranial–intracranial cerebrovascular bypass.

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A Critical Analysis of the Utility of Intraoperative Angiography  Voir?

Intraoperative digital subtraction angiography (ioDSA) is touted as the gold standard imaging evaluation for aneurysm clip constructs. Candid evaluations of its limitations are sparse.
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Artificial Stroke Clots: How Wide is the Gap to the Real World?  Voir?

Especially since the establishment of mechanical thrombectomy as part of standard stroke therapy, artificial thrombi have become important in the training of interventionalists as well as for the development and testing of devices. So far, these in vitro clots have lacked direct comparisons with ex vivo thrombi. We therefore compared the histologic appearance of dynamically produced clots with that of stroke thrombi acquired during mechanical recanalization.

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Subarachnoid Hemorrhage and Readmissions: National Rates, Causes, Risk Factors, and Outcomes in 16,001 Hospitalized Patients  Voir?

The acute complications of aneurysmal subarachnoid hemorrhage (aSAH) often lead to readmissions, which are linked to hospital reimbursement. The national rates, causes, risk factors, and outcomes associated with 30-day and 90-day readmission after aSAH have not previously been reported.
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Risk of Recurrence in Operated Parasagittal Meningiomas: A Logistic Binary Regression Model  Voir?

Parasagittal meningiomas arise from the arachnoid cells of the angle formed between the superior sagittal sinus (SSS) and the brain convexity. In this retrospective study, we focused on factors that predict early recurrence and recurrence times.
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The Relationship Between Intracranial Pressure and Age—Chasing Age-Related Reference Values  Voir?

No true reference values for intracranial pressure (ICP) in humans exist; current values are estimated from measurements in adults who undergo treatment in order to correct ICP. We report ICP values in a “pseudonormal” group of children and adults to examine if age affects ICP.
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Independent Association Between Preoperative Cognitive Status and Discharge Location After Surgery: A Strategy to Reduce Resource Use After Surgery for Deformity  Voir?

The aim of this study is to determine whether preoperative scores on a screening measure for cognitive status (the Saint Louis University mental status examination), were associated with discharge to a location other than home in older patients undergoing surgery for deformity.
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Hybrid Assistive Limb Exoskeleton HAL in the Rehabilitation of Chronic Spinal Cord Injury: Proof of Concept; the Results in 21 Patients  Voir?

The use of mobile exoskeletons is becoming more and more common in the field of spinal cord injury (SCI) rehabilitation. The hybrid assistive limb (HAL) exoskeleton provides a tailored support depending on the patient's voluntary drive.
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Predictive Factors of Headache Resolution After Chiari Type 1 Malformation Surgery  Voir?

Headache is the main and often isolated symptom of patients with Chiari type 1 malformation (CM1). Classically described as occipital and exacerbated by cough, headaches may be poorly characterized, making it difficult to establish CM1 as the underlying cause. Current guidelines for surgical posterior fossa decompression are undefined. The challenge is to distinguish headaches related to CM1 from headaches coincidentally coexisting with CM1. We aimed to determine predictive factors of headache resolution after surgery and applied to our cohort the Chiari Severity Index, a recently developed predictive prognostic score.

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5-ALA−Induced Fluorescence in Leptomeningeal Dissemination of Spinal Malignant Glioma  Voir?

5-Aminolevulinic acid (5-ALA)-fluorescence-guided resection of malignant glioma is well established in many neuro-oncology departments. In addition, the use of 5-ALA has been reported for cerebral metastases, meningioma, and spinal tumors. We report a case of a patient with a leptomeningeal spread of a K27M-mutated spinal anaplastic astrocytoma (World Health Organization° [WHO] III), which was detected by its faint 5-ALA-induced fluorescence.

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Unilateral Symptomatic Hypertrophic Olivary Degeneration Secondary to Midline Brainstem Cavernous Angioma: A Case Report and Review of the Literature  Voir?

Hypertrophic olivary degeneration (HOD) is a rare phenomenon in the dento-rubro-olivary pathway caused by lesion or disruption of the fibers of the Guillain-Mollaret triangle. Hemorrhage of pontine and midbrain cavernous angiomas can rarely lead to HOD portending neurologic deterioration and possible concomitant life-threatening complications; for this reason, it may define a poignant consideration in planning intervention.

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Spontaneous Intrauterine Depressed Skull Fractures: Report of 2 Cases Requiring Neurosurgical Intervention and Literature Review  Voir?

Spontaneous intrauterine depressed skull fractures (IDSFs) are rare fractures that often require neurosurgical evaluation and therapy. Most of the reported congenital depressions are secondary to maternal abdominal trauma or instrumentation during delivery. Spontaneous IDSFs occur in the setting of uneventful normal spontaneous vaginal delivery or cesarean section, without obvious predisposing risk factors. The etiology and optimal management of spontaneous IDSFs remain controversial.

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Symptomatic Vasospasms as a Life-Threatening Complication After Transsphenoidal Surgery  Voir?

To identify symptomatic vasospasms as a rare complication after transsphenoidal surgery, with emphasis on management and outcomes.
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Is Vertebral Column Resection Necessary in Correcting Severe and Rigid Thoracic Kyphoscoliosis? A Single-Institution Surgical Experience  Voir?

Three-column spinal osteotomies were developed to address severe and stiff kyphoscoliosis. However, the optimal choice of osteotomy in these patients is still unclear. This retrospective study aims to compare the outcomes and complications between grade 4 and grade 5 osteotomies in patients with severe and stiff thoracic kyphoscoliosis.

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Management of Through-and-Through Penetrating Skull Injury: A Railroad Spike That Transgressed the Anterior Skull Base  Voir?

Penetrating injuries involving foreign objects that transgress the entirety of the human skull present challenges in the management of vascular injuries, infectious risk, cerebrospinal fluid leak, and cosmetic repair. Ultimately, effective management of these injuries requires a multidisciplinary team and judicious surgical planning.

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Spontaneous Fusion of S2/S3 Spondyloptosis in an Adult  Voir?

Spondyloptosis is grade V on the Meyerding classification. Traumatic spondyloptosis can occur throughout the spinal column, particularly at junctional levels, and finding an ideal surgical strategy to address it remains a challenge for spinal surgeons. The sacrum is considered a united bone in adults, and sacral intersegmental spondyloptosis is extremely rare.

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Syrinx to Subarachnoid Shunting for Syringomyelia  Voir?

Surgery for syringomyelia generally aims to treat the underlying cause, if it is known. Optimal management is unclear for idiopathic syringomyelia, or when treatment of the putative cause has failed or is high risk. Syrinx to subarachnoid shunting is an option for these cases; a series is reported to assess the outcomes of this approach.

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Surgical Management of Giant Intracranial Meningioma: Operative Nuances, Challenges, and Outcome  Voir?

The giant intracranial meningioma (GIM) constitutes a different spectrum of brain tumors that invade the vital neurovascular structures, which makes the primary mode of treatment, surgery, a technically challenging one. The surgery for GIM is unique because of the large size of the tumor, prominent vascularity, entangling and limited visualization of various neurovascular structures, and severe cerebral edema. This study reports the authors surgical experience of 80 GIM cases, the operative challenges and surgical outcome.

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The Endoscopic Buccal Fat Pad Flap for Closure of Skull Base Defects: A Report of 5 Cases  Voir?

To demonstrate the clinical utility of the buccal fat pad flap (BFPF) for closing a variety of skull base defects.
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Postnatal Management of Myelomeningocele: Outcome with a Multidisciplinary Team Experience  Voir?

Myelomeningocele (MMC) is a complex neural tube defect. Few studies report the results of modern postnatal management. The goal of this study was to report the long-term outcome of a multidisciplinary approach of patients with MMC.
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Internal Carotid Artery and its Relationship with Structures in Sellar Region: Anatomic Study and Clinical Applications  Voir?

Complications of the internal carotid artery (ICA) in surgery are rare but severe. This study aimed to locate the ICA with 5 stationary bony structures in the sellar region: the anterior clinoid process, the tuberculum sellae, the bottom of the hypophyseal fossa, the posterior edge of the hypophyseal fossa, and the postclinoid process and to do measurements to determine their anatomic relationship with the ICA.

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Improved Microvascular Decompression in Treating Trigeminal Neuralgia: Application of Nest-Shaped Teflon Fibers  Voir?

To develop an improved technique for microvascular decompression (MVD) surgery using nest-shaped Teflon fibers.
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Schwannomas of the Frontal Sinus: Cases and Review of the Literature  Voir?

Although schwannomas are commonly found in the head and neck region, sinonasal tract involvement is extremely rare, estimated as <4%. The presence of these lesions in the frontal sinus is even less common.
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Top 100 Most-Cited Articles on Spontaneous Intracerebral Hemorrhage: A Bibliometric Analysis  Voir?

A bibliometric uses the citation count of an article to determine its impact on the clinical world. There is a paucity of literature concerning top article citations on spontaneous intracerebral hemorrhage (ICH). The main objective of this investigation was to bridge this gap and to provide understanding of the trends on the most influential articles written on this subject.

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Micro-Multileaf Collimator LINAC Radiosurgery for Vestibular Schwannomas  Voir?

This study evaluates the efficacy of linear accelerator (LINAC) radiosurgery using micro multi-leaf collimator technique (μMLC) in the treatment of a consecutive series of patients with vestibular schwannomas.
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WITHDRAWN: The modified impact factor; a letter to the editor  Voir?

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
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WITHDRAWN: Outcomes After Anterior Lumbar Interbody Fusion Versus Transforaminal Lumbar Interbody Fusion for the Treatment of Symptomatic L5–S1 Spondylolisthesis: A Prospective, Multi-Institutional Comparative Effectiveness Study  Voir?

Available online 25 September 2015
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WITHDRAWN: Refining the Role for Evacuation of Spontaneous Intracerebral Hematomas: Results of STICH II  Voir?

The Publisher regrets that this article is an accidental duplication of an article that has already been published, DOI of original article: http://dx.doi.org/10.1016/j.wneu.2014.08.046. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

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Upcoming Events  Voir?

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Editor's Choices  Voir?

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Editorial Board  Voir?

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Contents  Voir?

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Sentence Structure  Voir?

Many non-native English-speaking neurosurgeons struggle with communicating in the English language. I apologize at the outset here for the sole language of WORLD NEUROSURGERY being English. Such, however, is fortunately or unfortunately the case by necessity. The editorial board of WORLD NEUROSURGERY and I struggle along with international authors as we desperately try to assist all authors to craft manuscripts that are presentable in our neurosurgery journal. This, simply stated, is a problem of communication.

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Further Investigation About Copy Number Variations and Methylation of AURKA, KIF4A, and NUSAP1 in Glioblastoma  Voir?

We recently published the article “Identification of Driver Genes and Key Pathways of Glioblastoma Shows JNJ-7706621 as a Novel Antiglioblastoma Drug” in WORLD NEUROSURGERY.1 This article elaborately showed that 4 hub genes (aurora kinase A [AURKA], nuclear division cycle 80 [NDC80], kinesin super-family protein 4A [KIF4A], and nucleolar and spindle-associated protein 1 [NUSAP1]) were significantly overexpressed in glioblastoma (GBM) cells than in human normal glial cells and patients with low expression of these genes had a favorable prognosis.

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In Reply to “Cisternostomy: Surgical Alternative for Patients with Refractory Posttraumatic Intracranial Hypertension”  Voir?

We read with interest the letter to the editor on the subject of cisternostomy for traumatic brain injury (TBI). There is actually a heated debate in the neurosurgical community about the revolutionary technique of “cisternostomy” in cases of primary treatment of TBI and in those that fail maximal medical management of refractory intracranial hypertension following TBI. As the authors state, this technique could have better results when compared with the traditional form of treatment, namely decompressive craniectomy (DC).

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In Reply to “Neurosurgery Elective for Preclinical Medical Students: 6-Year Follow-up”  Voir?

We were pleased to read both the thoughtful response1 to our initial editorial2 and the follow-up article3 written by Zuckerman et al4 regarding the preclinical neurosurgery elective offered at Vanderbilt. We commend the authors and their entire department for their commitment to medical student education and neurosurgical training and appreciate their mutual willingness to foster a discussion regarding the benefits and drawbacks of various styles of exposure and early education in neurosurgery, including organized didactic sessions and one-on-one mentorship.

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Further Investigation About the Expression of SST, GAD2, and PVALB in Medulloblastoma  Voir?

We recently contributed the article titled “Identification of Driver Genes and Key Pathways of Pediatric Brain Tumors and Comparison of Molecular Pathogenesis Based on Pathologic Types” in WORLD NEUROSURGERY.1 This article elaborately proved that SST, GAD2, and PVALB play key roles in the glioma cells. In this letter, we would like to reveal some further verification experimental results in medulloblastoma (MED) cell lines, which is another important component of pediatric brain tumors.2

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In Reply to “In challenging the Myth of the Right Nondominant Hemisphere, Don't Go Too Far, Please”  Voir?

We thank the author for his comments in the letter to the editor “In Challenging the Myth of the Right Nondominant Hemisphere, Don't Go Too Far, Please.” We agree with the fact that motor control is subserved by a bilateral large-scale network: This is in accordance with observations we made during awake surgery using intraoperative electrostimulation mapping.1 However, it is worth noting that, in case of injury involving the circuit that subserves spatial cognition (notably composed of the parietotemporal junction and the part II of the superior longitudinal fasciculus),2 a severe permanent hemineglect is generated in most brain-damaged patients when the lesion is located in the right “nondominant” hemisphere, although rare cases of transient right hemineglect have been reported after a left hemisphere injury, but in fine with a functional recovery.

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In challenging the Myth of the Right Nondominant Hemisphere, Don't Go Too Far, Please  Voir?

As a neurologist with interest in laterality of motor control and hemispheric specialization,1-3 I read “Challenging the Myth of Right Nondominant Hemisphere: Lessons from Corticosubcortical Stimulation Mapping in Awake Surgery and Surgical Implications” by Vilasboas et al4 with interest and wish to record the following observation and comments bearing on the distinction between hemispheres:

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Cisternostomy: Surgical Alternative for Patients with Refractory Posttraumatic Intracranial Hypertension  Voir?

We read with great interest the article “Cisternostomy for Refractory Posttraumatic Intracranial Hypertension” published in a recent issue of WORLD NEUROSURGERY.1 According to the World Health Organization, it is estimated that traumatic brain injury (TBI) by 2020 will be the third cause of morbidity and mortality worldwide. Intracranial hypertension refractory to medical management causes the highest mortality in this patient population. Intracranial hypertension is a frequent complication of severe TBI.

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Craniovertebral Junction Instability–An Overview  Voir?

Mobility and stability are the hallmarks of craniovertebral junction. Whilst occipitoatlantal joint is the most stable joint, atlantoaxial joint is the most mobile joint of the body. Atlantoaxial joint is most mobile joint and it is also most likely to develop instability. On the other hand occipitoatlantal instability is rare and is seen in extreme degree of trauma or in paediatric patients with syndromal affection. In general, craniovertebral junction instability is equivalent to atlantoaxial instability and craniovertebral junction stabilization is equivalent to atlantoaxial stabilization.

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Neurosurgery Elective for Preclinical Medical Students: 6-Year Follow-up  Voir?

During the Spring semesters of 2012 and 2013, Zuckerman et al1 designed and implemented a preclinical elective for medical students to increase early exposure to the field of neurosurgery. At the course's conclusion, students were more likely to consider neurosurgery for a career and felt neurosurgeons had a better work-life balance and collegiality than previously perceived. However, the students' perception of residency difficulty did not change. The most impactful part of the course was the in-depth, open discussions with neurosurgery faculty members about the multiple facets of their lives both in and outside neurosurgery.

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The Decreasing Prevalence of the Arcuate Foramen  Voir?

The arcuate foramen (AF), or ponticulus posticus, is an anatomic variant of the first cervical vertebra that consists of a complete or partial osseous bridge over the groove for the vertebral artery and extends from the posterior aspect of the superior articular facet to the superior lateral border of the posterior arch. The AF has been associated with clinical symptoms, such as headache, migraine, neck pain, shoulder pain, arm pain, and vertebral artery dissection. We aimed to test whether the prevalence of the AF has decreased in the modern human population over the past centuries as a result of reduction in inbreeding and endogamy.

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Letter to the Editor Regarding “Aneurysm Clip Compression Technique in the Surgery of Aneurysms With Hard/Calcified Neck”  Voir?

Recently, we read a clinical trial entitled “Aneurysm Clip Compression Technique in the Surgery of Aneurysms with Hard/Calcified Neck” by Inci et al1 with great interest. In this article, they reported using a technique with a hemostatic clamp in aneurysms with hard/calcified necks.2 We have some concerns about this article. There have been major changes in the practice of neurosurgery,3 resulting in a substantial reduction in morbidity and mortality of aneurysmal subarachnoid hemorrhage.4,5 As a general rule, our clinical practice is usually guided by scientific principles6 including neurosurgical management of aneurysmal subarachnoid hemorrhage.

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Predicting Short-Term Outcome After Surgery for Primary Spinal Tumors Based on Patient Frailty; Methodologic Issues  Voir?

We were interested to read the article by Ahmed et al1 published in 2017. The researchers developed a preoperative frailty index (Spinal Tumor Frailty Index) for patients undergoing surgery for primary spinal column tumors to predict morbidity, mortality, and length of stay. They combined all complications into one category and found that the odds of this combined outcome is higher in patients with frailty compared with patients without frailty. Although the current study makes a valuable contribution to the field, some methodologic issues need to be taken into account.

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Craniovertebral Junction Transoral Approach: Predictive Factors of Complications  Voir?

The transoral approach provides the most direct exposure to extradural lesions of the ventral craniovertebral junction. The morbidity and mortality from this approach greatly limits its use because they are still feared and debated. Using univariable and multivariable logistic regression analyses, this study aims to identify the factors associated with short-term complications in patients undergoing the transoral approach.

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Traumatic Atlantoaxial Spondyloptosis Associated with Displaced Odontoid Fracture: Complete Reduction via Posterior Approach Using “Joint Remodeling” Technique  Voir?

Atlantoaxial spondyloptosis (AAS), which is defined as complete displacement of facets of atlas anterior to the facets of axis such that there is no contact between the 2 articulating surfaces, is an extremely rare manifestation of atlantoaxial instability. The reason for an extreme rarity of traumatic AAS is probably the severity of injury in traumatic AAS that is usually incompatible to life. It represents the most severe form of atlantoaxial dislocation, and complete reduction in such a case presents a real technical challenge because of the interlocking of C1-C2 facets.

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Considerations in Meta-Analysis Regarding Complications of Cortical Bone Trajectory versus Traditional Pedicle Screw Fixation  Voir?

Screw design and implantation have undergone a number of significant developments and advances, one of which includes the cortical bone trajectory (CBT) as an alternative method of pedicle fixation. This technique was initially described in traumatic procedures as the mediolaterosuperior technique1,2 for trauma fixation and later biomechanically via Santoni et al.3 CBT offers potential advantages in terms of reduced soft tissue and muscle dissection, reduced facet injury, and increased pullout strength.

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C1-2 and C2-3 Instability in the Presence of Hypoplastic Posterior Elements of C2 Vertebra: Report of 2 Cases  Voir?

We present 2 cases involving a previously unreported clinical situation in which basilar invagination, atlantoaxial instability, and C2-3 instability were associated with a bifid posterior arch of the axis bone.
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Atlantoaxial Fixation for Odontoid Fracture: Analysis of 124 Surgically Treated Cases  Voir?

The authors analyze 124 cases with fracture of odontoid process. All patients were surgically treated by posterior atlantoaxial fixation.
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Extraspinal-Interdural Surgical Approach for C2 Neurinomas—Report of an Experience with 50 Cases  Voir?

We report our experience with surgery in 50 patients with C2 neurinomas. The anatomic subtleties of these discrete forms of tumors and their surgical implications are analyzed.
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The Alar Ligaments: A Cadaveric and Radiologic Comparison Study  Voir?

A precise anatomical description of the alar ligaments is important to better understand their biomechanical and pathologic implications. Although there are several studies regarding their anatomy, the literature is inconsistent. To our knowledge, there are no reports that compare cadaveric morphologic findings with computed tomography (CT) images of the alar ligaments.

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Radiological Evaluation of 510 Cases of Basilar Invagination with Evidence of Atlantoaxial Instability (Group A Basilar Invagination)  Voir?

To evaluate the musculoskeletal and soft tissue neural alterations in cases with group A basilar invagination.
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Trabecular Anatomy of the Axis Vertebra: A Study of Shaded Volume-Rendered Computed Tomography Images  Voir?

To date, trabecular morphology studies have been conducted on thin-section computed tomography (CT) scans of cadaveric bone. Here we describe the trabecular anatomy of the axis vertebra as revealed by an innovative imaging tool.
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Walk the Line. The Surgical Highways to the Craniovertebral Junction in Endoscopic Approaches: A Historical Perspective  Voir?

We compiled a comprehensive literature review on the anatomic and clinical results of endoscopic approaches to the craniocervical junction (CVJ) to better contribute to identify the best strategy.
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Quality of Life After Craniovertebral Junction Meningioma Resection: Shaping the Real Neurologic and Functional Expectancies About These Surgeries in a Contemporary Large Multicenter Experience  Voir?

Craniovertebral junction (CVJ) meningiomas are one of the most surgically complex conditions in neuro-oncologic surgery. The aim of this work is to correlate our data with clinical outcome to outline factors leading to a worse functional prognosis.
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Transoral Versus Transnasal Approach for Craniovertebral Junction Pathologies: Never Say Never  Voir?

For many years, the microsurgical transoral approach (TOA) has been accepted as the “gold standard” for the surgical treatment of a variety of congenital, developmental, and acquired pathologies affecting the craniovertebral junction. In the present study, we try to investigate both experimental and clinical fronts of such a challenging surgery, starting from the updated literature experience. TOA is actually presented as an “old-fashioned” surgical technique dealing with possible bacterial contamination, the need of postoperative nose gastric tube feeding for a week, the possible nasopharyngeal incompetence, and the postoperative tongue swelling.

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Dernière mise à jour : 21/02/2018 : 15:15


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