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Sommaires des Revues - New England Journal of Medecine

The New England Journal of Medicine: Search Results in Neurology\Neurosurgery


The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Neurology\Neurosurgery. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.


Case 5-2018: A 63-Year-Old Man with Confusion after Stem-Cell Transplantation  Voir?

Presentation of Case. Dr. Joshua A. Cohen (Medicine): A 63-year-old man was admitted to this hospital with confusion and weakness 5 months after he had undergone allogeneic stem-cell transplantation for chronic lymphocytic leukemia (CLL). The patient had been generally well until 2 years before…

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Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy  Voir?

Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder that is characterized by atrophy and weakness of the skeletal muscles of the limbs and trunk and of the bulbar and respiratory muscles. It is caused by homozygous deletions or loss-of-function mutations in the gene…

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Case 4-2018: A Newborn with Thrombocytopenia, Cataracts, and Hepatosplenomegaly  Voir?

Presentation of Case. Dr. Madeleine I. Matthiesen (Medicine and Pediatrics): A newborn boy was transferred to the neonatal intensive care unit (ICU) of this hospital because of thrombocytopenia and abnormal results on an eye examination for red reflex and on a hearing screening. The patient was…

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Mogamulizumab (Anti-CCR4) in HTLV-1–Associated Myelopathy  Voir?

Human T-lymphotropic virus type 1 (HTLV-1) infects millions of persons worldwide and is the cause of adult T-cell leukemia–lymphoma (ATLL) and HTLV-1–associated myelopathy–tropical spastic paraparesis (HAM–TSP). The extent of infection, as indicated by the proviral load, is well correlated both…

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Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease  Voir?

The neuropathological hallmarks of Alzheimer’s disease include extracellular plaques containing amyloid beta (Aβ) and intracellular neurofibrillary tangles containing hyperphosphorylated tau protein, along with synaptic and neuronal losses. The Aβ hypothesis of the mechanism of Alzheimer’s disease…

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Creutzfeldt–Jakob Disease  Voir?

A 54-year-old man presented to the emergency department with a 3-week history of cognitive deterioration and functional decline. He was disoriented, inattentive, and disinhibited. Neurologic examination revealed horizontal gaze-evoked nystagmus, hyperreflexia on the left side, startle myoclonus,…

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Amyloid-Beta Solubility in the Treatment of Alzheimer’s Disease  Voir?

There is general agreement that Alzheimer’s disease will become a crisis by the middle of the century. The Alzheimer’s Association estimates that 5 million Americans currently have Alzheimer’s disease and that their loved ones devote nearly 18 billion hours annually toward their care. If…

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Monitoring Neuromuscular Function  Voir?

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Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging  Voir?

Endovascular thrombectomy has been shown to be effective for the treatment of acute ischemic stroke in patients with occlusion of the first segment of the middle cerebral artery or occlusion of the internal carotid artery if treatment is initiated within 6 hours. The results of the recently…
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Case 2-2018: A 41-Year-Old Woman with Vision Disturbances and Headache  Voir?

Presentation of Case. Dr. John H. Stone: A 41-year-old woman was evaluated in the rheumatology clinic of this hospital because of headaches and a 6-week history of intermittent, transient vision loss. Four years before the current presentation, a skin eruption on the right foot and a lesion on the…

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In the Balance  Voir?

A 71-year-old man presented to the emergency department with a 3-day history of changes in mental status. His partner noted that the patient had become more irritable than usual and was behaving as if other people were in the room with him when no one else was present. The patient had also had…

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Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain  Voir?

Arteriovenous malformations of the brain are high-flow vascular malformations that occur in approximately 15 per 100,000 persons and cause hemorrhagic stroke in children. They are tortuous, morphologically abnormal vascular channels between arteries and veins that lack an intervening capillary…

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Butterfly Glioma  Voir?

An 83-year-old woman presented to the emergency department with a 5-hour history of weakness in the left arm, drooping on the right side of the face, slurred speech, and urinary incontinence. A 7-week history of progressive functional and cognitive decline was reported. Gadolinium-enhanced magnetic…

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Multiple Sclerosis  Voir?

Multiple sclerosis is the most prevalent chronic inflammatory disease of the central nervous system (CNS), affecting more than 2 million people worldwide (at least 400,000 in the United States), and it is currently incurable. It is punctuated by fully or partially reversible episodes of neurologic…

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Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct  Voir?

Previous randomized trials that involved patients with acute stroke showed that endovascular thrombectomy had a clinical benefit when it was performed within 6 hours after the onset of stroke symptoms and that the benefit diminished as the interval between the time that the patient was last known…

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A New DAWN for Imaging-Based Selection in the Treatment of Acute Stroke  Voir?

Two years ago, the publication of the MR CLEAN trial (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands), which investigated endovascular mechanical thrombectomy for the treatment of acute ischemic stroke, was called "a first step in the…

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Trial of Contralateral Seventh Cervical Nerve Transfer for Spastic Arm Paralysis  Voir?

Spastic limb paralysis due to injury to a cerebral hemisphere from stroke, traumatic brain injury, or cerebral palsy is a cause of long-term disability. It is estimated that 30 to 60% of stroke survivors are unable to use their paralyzed hand. The spastic arm posture impairs activities of daily…

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Rewiring to Regain Function in Patients with Spastic Hemiplegia  Voir?

Spastic hemiplegia results from several relatively common disorders, including stroke, traumatic brain injury, and cerebral palsy. Frequently, upper-limb function is impaired. In this issue of the Journal, Zheng et al. report a new approach to the treatment of this condition: the use of a…
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Case 40-2017: A 32-Year-Old Woman with Headache, Abdominal Pain, Anemia, and Thrombocytopenia  Voir?

Presentation of Case. Dr. Emer McGrath (Neurology): A 32-year-old woman was admitted to this hospital in the fall because of severe headache and loss of peripheral vision. The patient had been in her usual state of health until 4 weeks before admission to this hospital, when she underwent elective…

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Ventriculoperitoneal-Shunt Placement for Normal-Pressure Hydrocephalus  Voir?

Figure 1.
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Dernière mise à jour : 21/02/2018 : 15:17


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